PT2897956T - Piridinonas bicíclicas inovadoras - Google Patents

Piridinonas bicíclicas inovadoras

Info

Publication number
PT2897956T
PT2897956T PT137920856T PT13792085T PT2897956T PT 2897956 T PT2897956 T PT 2897956T PT 137920856 T PT137920856 T PT 137920856T PT 13792085 T PT13792085 T PT 13792085T PT 2897956 T PT2897956 T PT 2897956T
Authority
PT
Portugal
Prior art keywords
novel bicyclic
pyridinones
bicyclic pyridinones
novel
bicyclic
Prior art date
Application number
PT137920856T
Other languages
English (en)
Portuguese (pt)
Inventor
William Am Ende Christopher
Eric Green Michael
Scott Johnson Douglas
Wayne Kauffman Gregory
John O'donnell Christopher
Chaturbhai Patel Nandini
Youngjin Pettersson Martin
Friederike Stepan Antonia
Michael Stiff Cory
Subramanyam Chakrapani
Phong Tran Tuan
Robert Verhoest Patrick
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT2897956T publication Critical patent/PT2897956T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
PT137920856T 2012-09-21 2013-09-06 Piridinonas bicíclicas inovadoras PT2897956T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21

Publications (1)

Publication Number Publication Date
PT2897956T true PT2897956T (pt) 2017-01-13

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137920856T PT2897956T (pt) 2012-09-21 2013-09-06 Piridinonas bicíclicas inovadoras

Country Status (46)

Country Link
US (3) US8916564B2 (Direct)
EP (1) EP2897956B1 (Direct)
JP (1) JP5844018B2 (Direct)
KR (1) KR101725696B1 (Direct)
CN (1) CN104662021B (Direct)
AP (1) AP2015008277A0 (Direct)
AR (1) AR092628A1 (Direct)
AU (1) AU2013319845B2 (Direct)
BR (1) BR112015006436A2 (Direct)
CA (1) CA2882386C (Direct)
CL (1) CL2015000717A1 (Direct)
CR (1) CR20150053A (Direct)
CU (1) CU20150021A7 (Direct)
CY (1) CY1118662T1 (Direct)
DK (1) DK2897956T3 (Direct)
DO (1) DOP2015000069A (Direct)
EA (1) EA026668B1 (Direct)
EC (1) ECSP15015594A (Direct)
ES (1) ES2609987T3 (Direct)
GE (1) GEP201706659B (Direct)
GT (1) GT201500069A (Direct)
HR (1) HRP20161558T1 (Direct)
HU (1) HUE031248T2 (Direct)
IL (1) IL237163A (Direct)
IN (1) IN2015DN01119A (Direct)
LT (1) LT2897956T (Direct)
MA (1) MA37886B1 (Direct)
MD (1) MD4583B1 (Direct)
ME (1) ME02571B (Direct)
MX (1) MX360599B (Direct)
MY (1) MY181891A (Direct)
NI (1) NI201500038A (Direct)
NZ (1) NZ704863A (Direct)
PE (1) PE20150686A1 (Direct)
PH (1) PH12015500376B1 (Direct)
PL (1) PL2897956T3 (Direct)
PT (1) PT2897956T (Direct)
RS (1) RS55426B1 (Direct)
SG (1) SG11201501074WA (Direct)
SI (1) SI2897956T1 (Direct)
TN (1) TN2015000084A1 (Direct)
TW (1) TWI500616B (Direct)
UA (1) UA110688C2 (Direct)
UY (1) UY35039A (Direct)
WO (1) WO2014045156A1 (Direct)
ZA (1) ZA201501195B (Direct)

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AU2014206834B2 (en) 2013-01-17 2017-06-22 Janssen Pharmaceutica Nv Novel substituted pyrido-piperazinone derivatives as gamma secretase modulators
ES2742078T3 (es) * 2013-10-04 2020-02-13 Pfizer Piridonas bicíclicas novedosas como moduladores de gamma-secretasa
US10562897B2 (en) 2014-01-16 2020-02-18 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators
KR101886945B1 (ko) * 2014-04-01 2018-08-08 화이자 인코포레이티드 감마-세크레타제 조절제로서의 크로멘 및 1,1a,2,7b-테트라히드로시클로프로파[c]크로멘 피리도피라진디온
PE20171318A1 (es) * 2015-02-03 2017-09-07 Pfizer Ciclopropabenzofuranil-piridopirazindionas novedosas
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KR20190098998A (ko) 2016-12-16 2019-08-23 파이프라인 테라퓨틱스, 아이엔씨. 달팽이관 시냅스질환의 치료 방법
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JOP20220130A1 (ar) 2019-12-06 2023-01-30 Vertex Pharma مجموعات تترا هيدروفيوران بها استبدال في صورة عوامل تعديل لقنوات الصوديوم
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
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