PT2456864E - Luciferases de oplophorus sintéticas com débito luminoso aumentado - Google Patents
Luciferases de oplophorus sintéticas com débito luminoso aumentado Download PDFInfo
- Publication number
- PT2456864E PT2456864E PT107170136T PT10717013T PT2456864E PT 2456864 E PT2456864 E PT 2456864E PT 107170136 T PT107170136 T PT 107170136T PT 10717013 T PT10717013 T PT 10717013T PT 2456864 E PT2456864 E PT 2456864E
- Authority
- PT
- Portugal
- Prior art keywords
- quot
- seq
- ogluc
- luciferase
- amino acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
- C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
- C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17483809P | 2009-05-01 | 2009-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2456864E true PT2456864E (pt) | 2016-01-20 |
Family
ID=42358981
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT107170136T PT2456864E (pt) | 2009-05-01 | 2010-05-03 | Luciferases de oplophorus sintéticas com débito luminoso aumentado |
| PT151866522T PT2990478T (pt) | 2009-05-01 | 2010-05-03 | Luciferases de oplophorus sintéticas com débito luminoso aumentado |
| PT181846999T PT3409764T (pt) | 2009-05-01 | 2010-05-03 | Luciferases de oplophorus sintéticas com débito luminoso aumentado |
| PT17154777T PT3181687T (pt) | 2009-05-01 | 2010-05-03 | Luciferases de oplophorus sintéticas com débito luminoso aumentado |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT151866522T PT2990478T (pt) | 2009-05-01 | 2010-05-03 | Luciferases de oplophorus sintéticas com débito luminoso aumentado |
| PT181846999T PT3409764T (pt) | 2009-05-01 | 2010-05-03 | Luciferases de oplophorus sintéticas com débito luminoso aumentado |
| PT17154777T PT3181687T (pt) | 2009-05-01 | 2010-05-03 | Luciferases de oplophorus sintéticas com débito luminoso aumentado |
Country Status (16)
| Country | Link |
|---|---|
| US (7) | US8557970B2 (https=) |
| EP (5) | EP2990478B1 (https=) |
| JP (2) | JP6038649B2 (https=) |
| KR (1) | KR101665352B1 (https=) |
| CN (2) | CN102459579B (https=) |
| AU (1) | AU2010242771B2 (https=) |
| BR (1) | BRPI1010019B1 (https=) |
| CA (1) | CA2758572A1 (https=) |
| DK (4) | DK2456864T3 (https=) |
| ES (5) | ES2795287T3 (https=) |
| IL (3) | IL215697B (https=) |
| LT (1) | LT3409764T (https=) |
| PL (5) | PL3409764T3 (https=) |
| PT (4) | PT2456864E (https=) |
| SG (3) | SG175180A1 (https=) |
| WO (1) | WO2010127368A1 (https=) |
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| ES2795287T3 (es) | 2009-05-01 | 2020-11-23 | Promega Corp | Luciferasas de Oplophorus sintéticas con mayor emisión de luz |
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| CN103180324A (zh) | 2010-11-02 | 2013-06-26 | 普罗美加公司 | 腔肠素衍生物及其使用方法 |
| JP5896679B2 (ja) * | 2011-03-15 | 2016-03-30 | オリンパス株式会社 | オオオバボタル由来ルシフェラーゼ |
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| BR112014020512B1 (pt) | 2012-02-21 | 2022-07-12 | Laboratory Corporation Of America Holdings | Métodos e sistemas para a detecção de microorganismos |
| US10519483B2 (en) | 2012-02-21 | 2019-12-31 | Laboratory Corporation Of America Holdings | Methods and systems for rapid detection of microorganisms using infectious agents |
| US20140099654A1 (en) | 2012-09-26 | 2014-04-10 | Promega Corporation | Real-time monitoring |
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| KR102292431B1 (ko) * | 2012-12-12 | 2021-08-20 | 프로메가 코포레이션 | 세포내 생물발광 공명 에너지 전이를 이용하여 생물활성제에 의한 세포 표적 결합의 인식 |
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| JP6604938B2 (ja) | 2013-03-15 | 2019-11-13 | プロメガ コーポレイション | タンパク質を官能基または固体表面に共有結合的に係留するための基質 |
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| US10168323B2 (en) * | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| AU2014241191A1 (en) | 2013-03-27 | 2015-10-22 | Sample Technologies, Inc. | Recombinant phage and bacterial detection methods |
| JP6040846B2 (ja) | 2013-04-08 | 2016-12-07 | Jnc株式会社 | セレンテラジン類縁体 |
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| JP6256118B2 (ja) * | 2014-03-11 | 2018-01-10 | Jnc株式会社 | エビルシフェラーゼの触媒蛋白質のキメラ遺伝子及びその使用法 |
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| JP6814132B2 (ja) * | 2014-09-12 | 2021-01-13 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | 内部タンパク質タグ |
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| EP3395803A1 (en) | 2017-04-28 | 2018-10-31 | Institut Pasteur | Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins |
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| CN118516381B (zh) * | 2024-07-22 | 2024-11-01 | 北京剂泰医药科技有限公司 | 编码荧光素酶的mRNA及其应用 |
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| ES2795287T3 (es) | 2009-05-01 | 2020-11-23 | Promega Corp | Luciferasas de Oplophorus sintéticas con mayor emisión de luz |
| SG10202103336SA (en) * | 2010-11-02 | 2021-04-29 | Promega Corp | Novel coelenterazine substrates and methods of use |
-
2010
- 2010-05-03 ES ES18184699T patent/ES2795287T3/es active Active
- 2010-05-03 PL PL18184699T patent/PL3409764T3/pl unknown
- 2010-05-03 DK DK10717013.6T patent/DK2456864T3/en active
- 2010-05-03 CA CA2758572A patent/CA2758572A1/en active Pending
- 2010-05-03 DK DK18184699.9T patent/DK3409764T3/da active
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