PL359969A1 - Sposób wytwarzania citalopramu - Google Patents

Sposób wytwarzania citalopramu

Info

Publication number
PL359969A1
PL359969A1 PL35996901A PL35996901A PL359969A1 PL 359969 A1 PL359969 A1 PL 359969A1 PL 35996901 A PL35996901 A PL 35996901A PL 35996901 A PL35996901 A PL 35996901A PL 359969 A1 PL359969 A1 PL 359969A1
Authority
PL
Poland
Prior art keywords
citalopram
preparation
Prior art date
Application number
PL35996901A
Other languages
English (en)
Inventor
Hans Petersen
Haleh Ahmadian
Robert Dancer
Original Assignee
H.Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H.Lundbeck A/S filed Critical H.Lundbeck A/S
Publication of PL359969A1 publication Critical patent/PL359969A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL35996901A 2000-08-18 2001-08-14 Sposób wytwarzania citalopramu PL359969A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001231 2000-08-18
PCT/DK2001/000542 WO2002016342A1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
PL359969A1 true PL359969A1 (pl) 2004-09-06

Family

ID=8159660

Family Applications (2)

Application Number Title Priority Date Filing Date
PL35982501A PL359825A1 (pl) 2000-08-18 2001-08-14 Sposób wytwarzania citalopramu
PL35996901A PL359969A1 (pl) 2000-08-18 2001-08-14 Sposób wytwarzania citalopramu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL35982501A PL359825A1 (pl) 2000-08-18 2001-08-14 Sposób wytwarzania citalopramu

Country Status (41)

Country Link
US (2) US6509483B2 (pl)
EP (2) EP1309582B1 (pl)
JP (2) JP2004506730A (pl)
KR (2) KR100887206B1 (pl)
CN (3) CN1159307C (pl)
AR (3) AR029597A1 (pl)
AT (4) ATE281447T1 (pl)
AU (6) AU2001279608B2 (pl)
BE (2) BE1013443A6 (pl)
BG (2) BG65964B1 (pl)
CA (2) CA2354880C (pl)
CH (2) CH691969A5 (pl)
CL (2) CL2008002412A1 (pl)
CZ (2) CZ294746B6 (pl)
DE (4) DE60106932T2 (pl)
DK (4) DK1309581T3 (pl)
EA (2) EA005811B1 (pl)
ES (4) ES2230347T3 (pl)
FI (2) FI20011621A7 (pl)
FR (2) FR2813077B1 (pl)
GB (2) GB2362647B (pl)
GR (1) GR1004074B (pl)
HK (2) HK1044538B (pl)
HR (2) HRP20030065A2 (pl)
HU (2) HUP0103291A3 (pl)
IE (2) IES20010760A2 (pl)
IL (2) IL144817A0 (pl)
IS (2) IS2120B (pl)
ME (2) MEP2208A (pl)
MX (2) MXPA03001329A (pl)
NL (2) NL1018775C1 (pl)
NO (2) NO326570B1 (pl)
NZ (2) NZ523877A (pl)
PL (2) PL359825A1 (pl)
PT (2) PT1309582E (pl)
RS (2) RS50287B (pl)
SI (2) SI1309581T1 (pl)
SK (2) SK287236B6 (pl)
UA (2) UA71676C2 (pl)
WO (2) WO2002016341A1 (pl)
ZA (1) ZA200106683B (pl)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
MXPA01010134A (es) 1999-04-14 2002-04-15 Lundbeck & Co As H Metodo para la preparacion de citalopram.
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
DK1298124T3 (da) 1999-10-25 2007-07-09 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
SK9282002A3 (en) 1999-12-28 2002-11-06 Lundbeck & Co As H Method for the preparation of citalopram, pharmaceutical composition comprising same and intermediates
ES2207312T3 (es) 1999-12-30 2004-05-16 H. Lundbeck A/S Metodo para la preparacion de citalopram.
UA72569C2 (uk) * 2000-01-14 2005-03-15 Х. Луннбек А/С Спосіб одержання 5-ціанофталіду
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
HUP0300273A2 (hu) * 2000-03-13 2003-06-28 H. Lundbeck A/S Eljárás 5-szubsztituált 1-(4-fluorfenil)-1,3-dihidroizobenzofurán-származékok lépésenkénti alkilezésére
KR20020080481A (ko) 2000-03-13 2002-10-23 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조 방법
EA005094B1 (ru) 2000-03-14 2004-10-28 Х.Лундбекк А/С Способ получения циталопрама
WO2001068632A1 (en) * 2000-03-16 2001-09-20 H. Lundbeck A/S Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
ES2228824T3 (es) 2000-12-22 2005-04-16 H. Lundbeck A/S Metodo de preparacion de citalopram puro.
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
AR040970A1 (es) 2002-08-12 2005-04-27 Lundbeck & Co As H Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
US20100087664A1 (en) * 2008-10-07 2010-04-08 Ravindra Vedantham Preparation of citalopram and salts thereof
JP6222973B2 (ja) * 2013-04-19 2017-11-01 日本テルペン化学株式会社 ジベンジルトリチオカーボネート誘導体
CN103936702A (zh) * 2014-05-07 2014-07-23 成都诺维尔生物医药有限公司 艾司西酞普兰杂质j的合成方法
EP3207018B1 (en) * 2014-10-14 2018-07-25 Syngenta Participations AG Process for the preparation of 1-(3,5-dichloro-4-fluoro-phenyl)-2,2,2-trifluoro-ethanone

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (pl) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE3926765A1 (de) 1989-08-12 1991-02-14 Hoechst Ag Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
KR100357975B1 (ko) 1997-07-08 2002-10-25 하. 룬트벡 아크티에 셀스카브 시탈로프램의 제조방법
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
DK1042310T3 (da) * 1997-11-11 2002-12-02 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
CA2291134C (en) 1998-10-20 2006-05-23 H. Lundbeck A/S Method for the preparation of citalopram
AU764161B2 (en) 1998-12-23 2003-08-14 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
MXPA01010134A (es) 1999-04-14 2002-04-15 Lundbeck & Co As H Metodo para la preparacion de citalopram.
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
WO2000012044A2 (en) 1999-10-25 2000-03-09 H. Lundbeck A/S Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
FR2805812A1 (fr) 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) * 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
ES2228824T3 (es) 2000-12-22 2005-04-16 H. Lundbeck A/S Metodo de preparacion de citalopram puro.
DE60100016T2 (de) 2000-12-28 2003-04-17 H. Lundbeck A/S, Valby Verfahren zur herstellung von reinem citalopram

Also Published As

Publication number Publication date
BG107584A (bg) 2004-01-30
NO20013943D0 (no) 2001-08-14
SK3222003A3 (en) 2003-08-05
EP1309582A1 (en) 2003-05-14
HUP0103295A3 (en) 2005-01-28
IES20010761A2 (en) 2002-02-20
CH691969A5 (de) 2001-12-14
BE1013444A6 (fr) 2002-01-15
AU2001100278A4 (en) 2001-09-13
DE60106933D1 (de) 2004-12-09
PL359825A1 (pl) 2004-09-06
EP1309582B1 (en) 2004-11-03
NO20013943L (no) 2002-02-19
CN1339436A (zh) 2002-03-13
FI20011621L (fi) 2002-02-19
DE10140029A1 (de) 2002-05-02
AR066694A2 (es) 2009-09-09
DK200101216A (da) 2002-02-19
US20020025982A1 (en) 2002-02-28
GB0119734D0 (en) 2001-10-03
US20020026062A1 (en) 2002-02-28
CN1339435A (zh) 2002-03-13
CZ20012958A3 (cs) 2002-04-17
AU7960901A (en) 2002-03-04
SK287236B6 (sk) 2010-04-07
DE60106932T2 (de) 2005-11-03
GB2362647A (en) 2001-11-28
IS2120B (is) 2006-06-15
MEP2208A (xx) 2010-02-10
AU2001100271A4 (en) 2001-09-13
BG65965B1 (bg) 2010-07-30
US6426422B1 (en) 2002-07-30
KR100887207B1 (ko) 2009-03-06
NO326772B1 (no) 2009-02-16
HK1047086A1 (en) 2003-02-07
DK1309581T3 (da) 2005-03-14
NL1018776C1 (nl) 2001-10-24
NL1018775C1 (nl) 2001-10-24
FI20011622A0 (fi) 2001-08-09
NO20013942D0 (no) 2001-08-14
DE10140028A1 (de) 2002-04-18
FR2813078A1 (fr) 2002-02-22
AU2001100278B4 (en) 2001-11-29
SI1309581T1 (en) 2005-04-30
AU2001100271B4 (en) 2001-11-29
IS6047A (is) 2001-10-20
EA005811B1 (ru) 2005-06-30
IES20010760A2 (en) 2002-02-20
KR20030022385A (ko) 2003-03-15
GB2365865B (en) 2002-07-17
CA2354877A1 (en) 2002-02-18
FI20011622L (fi) 2002-02-19
AU2001279608B2 (en) 2006-10-05
MXPA03001329A (es) 2003-06-06
CL2008002412A1 (es) 2009-01-02
CZ20012959A3 (cs) 2002-04-17
DE60106933T2 (de) 2005-12-01
ES2170734A1 (es) 2002-08-01
GR1004074B (el) 2002-11-26
HRP20030065A2 (en) 2005-02-28
DK1309582T3 (da) 2005-03-14
WO2002016341A1 (en) 2002-02-28
FR2813077B1 (fr) 2004-08-20
GB2362647B (en) 2002-09-18
YU6903A (sh) 2006-05-25
AR029597A1 (es) 2003-07-10
CN1159307C (zh) 2004-07-28
RS50287B (sr) 2009-09-08
SK3202003A3 (en) 2003-08-05
KR20030022378A (ko) 2003-03-15
DK200101219A (da) 2002-02-19
HK1044538B (zh) 2006-07-07
RS50258B (sr) 2009-07-15
ES2230347T3 (es) 2005-05-01
YU11503A (sh) 2006-05-25
HK1047086B (zh) 2005-04-22
GR20010100398A (el) 2002-05-24
EP1309581A1 (en) 2003-05-14
CH691968A5 (de) 2001-12-14
GB2365865A (en) 2002-02-27
IL144817A0 (en) 2002-06-30
ES2170735B2 (es) 2003-09-16
FI20011621A0 (fi) 2001-08-09
NZ523853A (en) 2004-07-30
BE1013443A6 (fr) 2002-01-15
CL2008002673A1 (es) 2009-01-02
ES2228920T3 (es) 2005-04-16
UA71676C2 (en) 2004-12-15
WO2002016342A1 (en) 2002-02-28
IS6048A (is) 2001-10-19
UA72340C2 (uk) 2005-02-15
CN1222517C (zh) 2005-10-12
JP2004506729A (ja) 2004-03-04
ZA200106683B (en) 2002-08-05
JP2004506730A (ja) 2004-03-04
CZ295863B6 (cs) 2005-11-16
BG65964B1 (bg) 2010-07-30
SI1309582T1 (en) 2005-06-30
US6509483B2 (en) 2003-01-21
EA005946B1 (ru) 2005-08-25
ATE281448T1 (de) 2004-11-15
HK1044538A1 (en) 2002-10-25
FR2813077A1 (fr) 2002-02-22
HRP20030064A2 (en) 2005-02-28
CN1239490C (zh) 2006-02-01
NO326570B1 (no) 2009-01-12
IL144816A0 (en) 2002-06-30
CZ294746B6 (cs) 2005-03-16
HUP0103291A2 (hu) 2002-05-29
MEP2308A (xx) 2010-02-10
AU7960801A (en) 2002-03-04
CA2354880C (en) 2003-06-03
KR100887206B1 (ko) 2009-03-06
ES2170735A1 (es) 2002-08-01
NZ523877A (en) 2004-08-27
GB0119733D0 (en) 2001-10-03
IS2121B (is) 2006-06-15
EP1309581B1 (en) 2004-11-03
DE60106932D1 (de) 2004-12-09
PT1309582E (pt) 2005-03-31
ES2170734B2 (es) 2003-09-16
IL144816A (en) 2005-09-25
CA2354877C (en) 2006-05-02
CA2354880A1 (en) 2002-01-22
AR029598A1 (es) 2003-07-10
HK1068069A1 (en) 2005-04-22
AU2001279609B2 (en) 2007-09-06
FI20011621A7 (fi) 2002-02-19
HUP0103291A3 (en) 2003-02-28
HUP0103295A2 (hu) 2002-05-29
CN1515564A (zh) 2004-07-28
HU0103291D0 (en) 2001-10-28
AT4946U1 (de) 2002-01-25
ATE281447T1 (de) 2004-11-15
EA200300279A1 (ru) 2003-08-28
PT1309581E (pt) 2005-03-31
BG107583A (bg) 2004-01-30
EA200300277A1 (ru) 2003-08-28
AT5026U1 (de) 2002-02-25
NO20013942L (no) 2002-02-19
SK287008B6 (sk) 2009-09-07
FI20011622A7 (fi) 2002-02-19
FR2813078B1 (fr) 2004-04-02
MXPA03000913A (es) 2003-06-24

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