PL3464336T3 - Związki - Google Patents

Związki

Info

Publication number
PL3464336T3
PL3464336T3 PL17807519T PL17807519T PL3464336T3 PL 3464336 T3 PL3464336 T3 PL 3464336T3 PL 17807519 T PL17807519 T PL 17807519T PL 17807519 T PL17807519 T PL 17807519T PL 3464336 T3 PL3464336 T3 PL 3464336T3
Authority
PL
Poland
Prior art keywords
compounds
Prior art date
Application number
PL17807519T
Other languages
English (en)
Inventor
Leen H. Kawas
Jasbir Singh
Lansing Joseph Stewart
William R. Baker
Original Assignee
Athira Pharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Athira Pharma, Inc. filed Critical Athira Pharma, Inc.
Publication of PL3464336T3 publication Critical patent/PL3464336T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0217Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -C(=O)-C-N-C(=O)-N-C-C(=O)-
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL17807519T 2016-06-01 2017-06-01 Związki PL3464336T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662344305P 2016-06-01 2016-06-01
EP17807519.8A EP3464336B1 (en) 2016-06-01 2017-06-01 Compounds
PCT/US2017/035547 WO2017210489A1 (en) 2016-06-01 2017-06-01 Compounds

Publications (1)

Publication Number Publication Date
PL3464336T3 true PL3464336T3 (pl) 2022-05-16

Family

ID=60478958

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17807519T PL3464336T3 (pl) 2016-06-01 2017-06-01 Związki

Country Status (16)

Country Link
US (2) US11021514B2 (pl)
EP (2) EP3464336B1 (pl)
JP (4) JP2019525947A (pl)
CN (3) CN116655730A (pl)
AU (3) AU2017273857B2 (pl)
CA (1) CA3026074A1 (pl)
CY (1) CY1125184T1 (pl)
DK (1) DK3464336T3 (pl)
ES (1) ES2912035T3 (pl)
HR (1) HRP20220479T1 (pl)
LT (1) LT3464336T (pl)
PL (1) PL3464336T3 (pl)
RS (1) RS63143B1 (pl)
SI (1) SI3464336T1 (pl)
SM (1) SMT202200173T1 (pl)
WO (1) WO2017210489A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116655730A (zh) 2016-06-01 2023-08-29 雅斯娜 用于治疗多种疾病的n-己酸-l-酪氨酸-l-异亮氨酸-(6)-氨基己酰胺的衍生物
JP7624924B2 (ja) * 2018-09-29 2025-01-31 江▲蘇▼▲亞▼虹医▲薬▼科技股▲フン▼有限公司 ニトロキソリンプロドラッグ及びその使用
JP2024524679A (ja) * 2021-07-16 2024-07-05 アティラ・ファーマ・インコーポレイテッド アルツハイマー病の処置方法
KR20240038980A (ko) * 2021-07-23 2024-03-26 아티라 파마, 인코포레이티드 파킨슨병 및/또는 루이체 질환 또는 장애(들)의 치료 방법
TW202408503A (zh) 2022-05-04 2024-03-01 美商雅斯娜製藥公司 治療纖維化之方法
KR20250005230A (ko) 2022-05-04 2025-01-09 아티라 파마, 인코포레이티드 신경염증성 병태를 치료하는 방법
CA3248537A1 (en) 2022-05-04 2023-11-09 Athira Pharma, Inc. METHODS OF TREATMENT FOR NEUROPATHIES
CN114907288B (zh) * 2022-05-13 2023-12-08 中国医学科学院医药生物技术研究所 硝基苯类化合物在制备铜绿假单胞菌群体感应抑制剂中的应用
EP4618996A1 (en) 2022-11-18 2025-09-24 Athira Pharma, Inc. Methods of treating inflammatory conditions
WO2024218682A1 (en) 2023-04-18 2024-10-24 Assia Chemical Industries Ltd. Solid state forms of fosgonimeton and salts thereof

Family Cites Families (243)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639456A (en) 1980-06-10 1987-01-27 Omnichem S.A. Vinblastin-23-oyl amino acid derivatives
GB8311286D0 (en) 1983-04-26 1983-06-02 Searle & Co Carboxyalkyl peptide derivatives
DE3320175A1 (de) 1983-06-03 1984-12-06 Boehringer Mannheim Gmbh, 6800 Mannheim Aminosaeure- bzw. peptidderivate, verfahren zu deren herstellung und verwendung als arzneimittel
US4477440A (en) 1983-09-14 1984-10-16 Merck & Co., Inc. Renin inhibitors containing an n-terminal disulfide cycle
EP0163237A3 (en) 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
JPS63503380A (ja) 1986-01-16 1988-12-08 アボット・ラボラトリーズ ペプチド類似体
US5378691A (en) 1988-04-14 1995-01-03 Merck Patent Gesellschaft Mit Beschrankter Haftung Amino acid derivatives
WO1990002137A1 (en) 1988-08-19 1990-03-08 The Upjohn Company Renin inhibitory peptides containing suleptanic acid or derivatives thereof
US5180816A (en) 1988-08-24 1993-01-19 Centocor One vial method for labeling protein/linker conjugates with technetium-99M
CA2003382A1 (en) 1988-11-21 1990-05-21 Hollis D. Kleinert Method for treating vascular diseases
DE3912829A1 (de) 1989-04-19 1990-10-25 Bayer Ag Verwendung von renininhibitorischen peptiden als mittel gegen retroviren
DE4004820A1 (de) 1989-08-05 1991-04-25 Bayer Ag Renininhibitoren, verfahren zur herstellung und ihre verwendung in arzneimitteln
DE3915361A1 (de) 1989-05-11 1990-11-15 Merck Patent Gmbh Cyclopeptide
US5240913A (en) 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
CA2035917C (en) 1990-02-13 2001-10-02 John L. Krstenansky Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin
US5284828A (en) 1990-05-14 1994-02-08 Fujisawa Pharmaceutical Co. Ltd. Peptide compound and its preparation
AU648140B2 (en) 1991-02-01 1994-04-14 Virtual Drug Development, Inc. Reverse antimicrobial peptides and antimicrobial compositions
US5190924A (en) 1991-02-13 1993-03-02 Boc Health Care, Inc. Peptide amides and amide dimers useful as muscle relaxants
ATE195948T1 (de) 1991-05-16 2000-09-15 Warner Lambert Co Endothelinantagonisten
US5382569A (en) 1991-05-16 1995-01-17 Warner-Lambert Company Endotherlin antagonists
US5190922A (en) 1991-06-04 1993-03-02 Abbott Laboratories Terminally modified tri-, tetra- and pentapeptide anaphylatoxin receptor ligands
CA2071674C (en) 1991-06-21 2003-08-19 Kevin T. Chapman Peptidyl derivatives as inhibitors of interleukin-1.beta. converting enzyme
DE4122885A1 (de) 1991-07-11 1993-01-21 Hoechst Ag Verfahren zur diastereoselektiven reduktiven pinakol-kupplung von homochiralen (alpha)-aminoaldehyden
EP0533226A3 (en) 1991-08-16 1993-08-18 Merck & Co. Inc. Novel chromophore containing compounds
US6348570B1 (en) 1991-08-16 2002-02-19 Merck & Co., Inc. Chromophore containing compounds and their use in determining interleukin-1β convertase activity
JPH05117169A (ja) 1991-10-29 1993-05-14 Mitsubishi Kasei Corp クロロメチルケトンの製法
US5223535A (en) 1991-10-29 1993-06-29 G. D. Searle & Co. Propargyl glycine amino propargyl diol compounds for treatment of hypertension
US5227401A (en) 1991-10-29 1993-07-13 G. D. Searle & Co. Ethynyl alanine amino diol compounds for treatment of hypertension
WO1993012076A1 (en) 1991-12-13 1993-06-24 Corvas International Inc. Reagents for automated synthesis of peptide analogs
EP0547699A1 (en) 1991-12-19 1993-06-23 Merck & Co. Inc. Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme
JPH05178890A (ja) 1991-12-26 1993-07-20 Banyu Pharmaceut Co Ltd エンドセリン拮抗性化合物
WO1993014777A1 (en) 1992-01-31 1993-08-05 Merck & Co., Inc. PEPTIDYL DERIVATIVES AS INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME
ATE169224T1 (de) 1992-02-21 1998-08-15 Merck & Co Inc Peptidylderivate und inhibitoren des interleukin- 1-g(b)-konvertierenden enzyms
US5430062A (en) 1992-05-21 1995-07-04 Research Corporation Technologies, Inc. Stilbene derivatives as anticancer agents
EP0641301A1 (en) 1992-05-21 1995-03-08 Research Corporation Technologies, Inc. Stilbene derivatives as anticancer agents
EP0647239A4 (en) 1992-06-24 1997-07-02 Univ Washington ANGIOTENSIN IV PEPTIDES, AND RECEPTOR.
CA2144067A1 (en) 1992-09-24 1994-03-31 Ronald N. Zuckermann Synthesis of n-substituted oligomers
EP0600832A1 (de) 1992-11-27 1994-06-08 Ciba-Geigy Ag Diaminobenzoe- und Diaminophthalsäurederivate und ihre Verfahren als Proteinkinase-Inhibitoren
IL107719A0 (en) 1992-12-21 1994-02-27 Du Pont Imidazolones their manufacture and their use as herbicides
JPH06192199A (ja) 1992-12-25 1994-07-12 Mitsubishi Kasei Corp ケトン誘導体
WO1994022906A1 (en) 1993-03-26 1994-10-13 Warner-Lambert Company Inhibitors of endothelin converting enzyme
DE4311021A1 (de) 1993-03-31 1994-10-27 Diagnostikforschung Inst Bifunktionelle Chelatbildner, deren Technetium- und Rhenium-Komplexe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende radiopharmazeutische Mittel
WO1994028012A1 (en) 1993-05-28 1994-12-08 Warner-Lambert Company Hydroxamate inhibitors of endothelin converting enzyme
US5854388A (en) 1993-06-24 1998-12-29 Washington State University Research Foundation Angiotensin IV peptides and receptor
DE4321306A1 (de) 1993-06-26 1995-01-05 Sanol Arznei Schwarz Gmbh Disulfide
GB9323165D0 (en) 1993-11-10 1994-01-05 Chiros Ltd Compounds
DE4345062A1 (de) 1993-12-31 1995-07-13 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von Viruserkrankungen
US5686419A (en) 1994-01-21 1997-11-11 Georgia Tech Research Corp. Basic α-aminoalkylphosphonate derivatives
GB2292149A (en) 1994-08-09 1996-02-14 Ferring Res Ltd Peptide inhibitors of pro-interleukin-1beta converting enzyme
US20010046668A1 (en) 1994-10-21 2001-11-29 G.D. Searle & Co. Fluorescence polarization method for determining protease activity
US5831004A (en) 1994-10-27 1998-11-03 Affymax Technologies N.V. Inhibitors of metalloproteases, pharmaceutical compositions comprising same and methods of their use
US5840698A (en) 1994-10-27 1998-11-24 Affymax Technologies N.V. Inhibitors of collagenase-1 and stormelysin-I metalloproteases, pharmaceutical compositions comprising same and methods of their use
EP0793673A1 (en) 1994-11-24 1997-09-10 Takeda Chemical Industries, Ltd. Alpha-ketoamide derivatives as cathepsin l inhibitor
EP0731107A1 (en) 1995-02-13 1996-09-11 Takeda Chemical Industries, Ltd. Production of aldehyde derivatives
JPH08262673A (ja) 1995-03-22 1996-10-11 Fuji Photo Film Co Ltd 銀塩拡散転写法による画像形成方法
CA2218679A1 (en) 1995-04-21 1996-10-24 Merck & Co., Inc. Apopain
US5798442A (en) 1995-04-21 1998-08-25 Merck Frosst Canada, Inc. Peptidyl derivatives as inhibitors of pro-apoptotic cysteine proteinases
CN1192746A (zh) 1995-07-07 1998-09-09 财团法人相模中央化学研究所 肽衍生物和血管紧张素iv受体激动剂
GB9517060D0 (en) * 1995-08-17 1995-10-25 Ciba Geigy Ag Acylated oligopeptide derivatives
US5763576A (en) 1995-10-06 1998-06-09 Georgia Tech Research Corp. Tetrapeptide α-ketoamides
WO1997016410A1 (en) 1995-10-30 1997-05-09 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5817757A (en) 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
US6121489A (en) 1996-03-05 2000-09-19 Trega Biosciences, Inc. Selectively N-alkylated peptidomimetic combinatorial libraries and compounds therein
WO1997040071A1 (en) 1996-04-19 1997-10-30 Novo Nordisk A/S Compounds with growth hormone releasing properties
SE9603461D0 (sv) 1996-09-23 1996-09-23 Astra Ab New compounds
SE9603468D0 (sv) 1996-09-23 1996-09-23 Astra Ab New compounds
GB9623908D0 (en) 1996-11-18 1997-01-08 Hoffmann La Roche Amino acid derivatives
SI9600371B (sl) 1996-12-18 2005-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Etilidenski derivati tricikličnih karbapenemov
ATE261988T1 (de) 1996-12-27 2004-04-15 Boehringer Ingelheim Ca Ltd Peptidomimetische inhibitoren von der protease des menschlichen cytomegalovirus
GB2324529A (en) 1997-02-21 1998-10-28 Merck & Co Inc A combinatorial library based on a tetrapeptide substituted with aminomethylcoumarin for characterizing proteases
CA2313649A1 (en) 1997-12-12 1999-06-24 Tadanori Morikawa Novel metalloproteinase inhibitors
CA2225325A1 (en) 1997-12-19 1999-06-19 The University Of British Columbia Hemiasterlin analogs
US6468977B1 (en) 1998-03-02 2002-10-22 Apotex Inc. Thiadiazole compounds useful as inhibitors of cysteine activity dependent enzymes
GB9806815D0 (en) 1998-03-30 1998-05-27 Hoffmann La Roche Amino acid derivatives
US6022696A (en) 1998-04-02 2000-02-08 Washington State University Research Foundation Methods of identifying agonists or antagonists of angiotensin IV
GB9809664D0 (en) 1998-05-06 1998-07-01 Hoffmann La Roche a-Ketoamide derivatives
ES2335827T3 (es) 1998-07-20 2010-04-05 Ipsen Pharma Analogos peptidos de pacap.
US6242563B1 (en) 1998-07-20 2001-06-05 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Peptide analogues
US6140342A (en) 1998-09-17 2000-10-31 Pfizer Inc. Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines
GB9828074D0 (en) * 1998-12-18 1999-02-17 Glaxo Group Ltd Therapeutically useful compounds
JP2000250182A (ja) 1999-03-04 2000-09-14 Fuji Photo Film Co Ltd カラー拡散転写写真画像形成方法
EP1059302A1 (en) 1999-06-08 2000-12-13 Aventis Pharma Deutschland GmbH Factor VIIa inhibitors
DE19947154A1 (de) 1999-10-01 2001-10-04 Bayer Ag Substituierte 2-Thio-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung
US20070160574A1 (en) 2000-04-12 2007-07-12 Ahmed Merzouk Design of CXC chemokine analogs for the treatment of human diseases
US20060233748A1 (en) 2002-09-13 2006-10-19 Ahmed Merzouk Mimetics of interleukin-8 and methods of using them in the prevention, treatment, diagnosis, and ameliorization of symptoms of a disease
US20070116669A1 (en) 2002-09-13 2007-05-24 Chemokine Therapeutics Corporation Interferon-inducible protein-10 (IP-10 or CXCL10) chemokine analogs for the treatment of human diseases
WO2001079263A1 (en) 2000-04-14 2001-10-25 Nippon Shinyaku Co., Ltd. Peptide derivatives and medicinal compositions
JP2002145898A (ja) 2000-11-09 2002-05-22 Ajinomoto Co Inc 新規グリチルレチン酸誘導体及び甘味剤
FR2816509B1 (fr) 2000-11-15 2004-02-06 Sod Conseils Rech Applic Association d'inhibiteurs de calpaine et de piegeurs des formes reactives de l'oxygene
JP2003040784A (ja) 2001-01-31 2003-02-13 Japan Science & Technology Corp 血糖降下剤
EP1351992B1 (en) 2001-01-16 2011-03-02 Ramot at Tel Aviv University Ltd. Hybrid peptides for treatment of bacteremia and septicemia
KR20040004642A (ko) 2001-05-23 2004-01-13 덴드레온 샌 디에고 엘엘씨 세포 표면 프로테아제에 의해 활성화되는 접합체 및 이의치료학적 용도
AR037938A1 (es) 2001-12-21 2004-12-22 Syngenta Participations Ag Derivados de avermectina b1 que tienen un substituyente de aminosulfoniloxilo en la posicion 4''
AU2003208105C1 (en) 2002-02-07 2009-08-13 J-Pharma Co., Ltd. Aromatic amino acid derivatives and medicinal compositions
US20040001801A1 (en) 2002-05-23 2004-01-01 Corvas International, Inc. Conjugates activated by cell surface proteases and therapeutic uses thereof
US7056947B2 (en) 2002-07-05 2006-06-06 Georgia Tech Research Corp. Aza-peptide epoxides
US8013014B2 (en) 2002-07-05 2011-09-06 Georgia Tech Research Corporation Aza-peptide epoxides
BR0305628A (pt) 2002-07-09 2004-09-08 Palatin Technologies Inc Composição farmacêutica para tratar disfunção sexual num mamìfero compreendendo peptìdeo e seu uso
WO2004018644A2 (en) 2002-08-26 2004-03-04 Wisconsin Alumni Research Foundation HETEROGENEOUS FOLDAMERS CONTAINING α, β, AND/OR Ϝ-AMINO ACIDS
DK2949658T3 (en) * 2003-03-03 2018-10-01 Dyax Corp Peptides that specifically bind HGF receptor (cMet) and uses thereof
DE10320453A1 (de) 2003-05-08 2004-11-25 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Bioisostere von Actinonin
PT1648998E (pt) * 2003-07-18 2014-11-04 Amgen Inc Agentes de ligação específica ao factor de crescimento do hepatócito
ATE469921T1 (de) 2003-08-07 2010-06-15 Enkam Pharmaceuticals As Lpa-haltige verbindungen
US7118747B2 (en) 2003-09-30 2006-10-10 Pacific Northwest Biotechnology Inc. AT4 receptor ligands as angiogenic, anti-angiogenic, and anti-tumor agents
SE0302853D0 (sv) 2003-10-29 2003-10-29 Astrazeneca Ab Chemical compounds
EP1723124A1 (en) 2004-02-18 2006-11-22 Georgia Tech Research Corporation Propenoyl hydrazides
JP4502115B2 (ja) 2004-04-23 2010-07-14 信越化学工業株式会社 含窒素有機化合物、化学増幅型レジスト材料及びパターン形成方法
MXPA06012391A (es) 2004-04-30 2007-01-31 Theraptosis S A Inhibidores de caspasa-2 y sus aplicaciones biologicas.
WO2005113580A1 (en) 2004-05-21 2005-12-01 Pfizer Inc. Anticoronviral compounds and compositions, their pharmaceutical uses and materials for their synthesis
US20060063803A1 (en) 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7521427B2 (en) 2004-11-09 2009-04-21 Georgia Tech Research Corporation Peptidyl allyl sulfones
WO2006061714A2 (en) 2004-12-09 2006-06-15 Pfizer Inc. Anticoronaviral compounds and compositions, their pharmaceutical uses and materials for their synthesis
DE102005044319A1 (de) 2005-09-16 2007-03-22 Curacyte Chemistry Gmbh 2-(Aminomethyl)-5-Chlor-Benzylamid-Derivate und ihre Verwendung als Hemmstoffe des Gerinnungsfaktors Xa
US7790745B2 (en) 2005-10-21 2010-09-07 Bristol-Myers Squibb Company Tetrahydroisoquinoline LXR Modulators
GB0522061D0 (en) 2005-10-28 2005-12-07 Glaxo Group Ltd Chemical process
US7705009B2 (en) 2005-11-22 2010-04-27 Hoffman-La Roche Inc. 4-aminopyrimidine-5-thione derivatives
US20080090760A2 (en) 2005-12-09 2008-04-17 Todd Hembrough Compositions and Methods for Inhibiting Cellular Proliferation
JP5079265B2 (ja) 2006-06-13 2012-11-21 ポリプラスチックス株式会社 安定化ポリアセタール樹脂の製造方法
EP1873527A1 (en) 2006-06-30 2008-01-02 Schwarz Pharma Ag Method for identifying CRMP modulators
TWI397417B (zh) 2006-06-15 2013-06-01 Ucb Pharma Gmbh 具有協同抗驚厥功效之醫藥組成物
CN101466390B (zh) 2006-06-15 2014-03-12 优时比制药有限公司 用于治疗难治性癫痫持续状态的肽类化合物
CA2692240C (en) 2006-06-22 2018-03-13 Biosurface Engineering Technologies, Inc. Composition and method for delivery of bmp-2 amplifier/co-activator for enhancement of osteogenesis
US8236761B2 (en) 2006-07-07 2012-08-07 Washington State University Research Foundation C-Met receptor regulation by angiotensin IV (AT4) receptor ligands
US7910555B2 (en) 2006-07-07 2011-03-22 Washington State University Research Foundation C-Met receptor regulation by angiotensin IV (AT4 ) receptor ligands
US9066901B2 (en) 2006-07-07 2015-06-30 Washington State University C-Met receptor regulation by angiotensin IV (AT4) receptor ligands
EP1961765A1 (en) 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
DE602006012515D1 (de) 2006-12-15 2010-04-08 Giuseppe Campiani Neuartige mit Taxan verwandte Peptide und deren Verwendung
EP1977765A1 (en) 2007-04-03 2008-10-08 Diatos Peptide prodrugs
EP2162451A4 (en) 2007-06-25 2012-04-18 Neurogen Corp PIPERAZINYL-OXOALKYL-TETRAHYDRO-BETA-CARBOLINE AND RELATED ANALOGUE
CA2691662A1 (en) 2007-07-02 2009-01-08 F. Hoffmann-La Roche Ag Imidazole derivatives as ccr2 receptor antagonists
CA2700691A1 (en) 2007-10-01 2009-04-09 F. Hoffmann-La Roche Ag New biaryl derivatives
WO2009059002A2 (en) 2007-10-30 2009-05-07 The Regents Of The University Of Michigan Office Of Technology Transfer Macrocyclization of compounds from solid support using thioesterases
EP2083009A1 (de) 2008-01-22 2009-07-29 Grünenthal GmbH Substituierte Tethrahydroimidazopyridin-Verbindungen und deren Verwendung in Arzneimitteln
US9096649B2 (en) 2008-02-08 2015-08-04 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
CA2714251C (en) 2008-02-08 2017-08-15 Aileron Therapeutics, Inc. Therapeutic peptidomimetic macrocycles
WO2009105782A1 (en) 2008-02-21 2009-08-27 Sequoia Pharmaceuticals, Inc. Hiv protease inhibitor and cytochrome p450 inhibitor combinations
ES2428716T3 (es) 2008-02-22 2013-11-11 F. Hoffmann-La Roche Ag Moduladores de beta-amiloide
AU2009225984A1 (en) 2008-03-21 2009-09-24 Chlorion Pharma, Inc. Substituted pyrrolidine and piperidine compounds, derivatives thereof, and methods for treating pain
US8367680B2 (en) 2008-03-28 2013-02-05 Wisconsin Alumni Research Foundation Antibacterial small molecules and methods for their synthesis
WO2010014179A1 (en) 2008-07-31 2010-02-04 Duke University Photolabile caged transition metal complexes and methods of using the same
EP2331112A1 (en) 2008-08-19 2011-06-15 Ferring B.V. Peptidic pth receptor agonists
WO2010039461A2 (en) 2008-10-03 2010-04-08 The Johns Hopkins University Methods for synthesis and uses of inhibitors of ghrelin o-acyltransferase as potential therapeutic agents for obesity and diabetes
ES2567455T3 (es) 2008-10-10 2016-04-22 Dara Biosciences, Inc. Nanoemulsiones que comprenden derivados de espicamicina para su uso en el tratamiento del dolor
WO2010080609A1 (en) 2008-12-19 2010-07-15 Indiana University Research And Technology Corporation Amide-based insulin prodrugs
WO2010080605A1 (en) 2008-12-19 2010-07-15 Indiana University Research And Technology Corporation Dipeptide linked medicinal agents
US20120142786A1 (en) 2009-02-20 2012-06-07 Regina Goralczyk Oregano extract for alertness
US8835602B2 (en) 2009-03-06 2014-09-16 Indian Institute Of Science Templates for nucleation and propagation of peptide secondary structure
US20120157401A1 (en) 2009-05-27 2012-06-21 Ptc Therapeutics, Inc. Methods for treating neurofibromatosis
US8703726B2 (en) 2009-05-27 2014-04-22 Ptc Therapeutics, Inc. Methods for treating prostate conditions
US20120157402A1 (en) 2009-05-27 2012-06-21 Liangxian Cao Methods for treating brain tumors
WO2010138652A1 (en) 2009-05-27 2010-12-02 Ptc Therapeutics, Inc. Methods for treating kaposi sarcoma
EP2434891B9 (en) 2009-05-27 2021-05-05 PTC Therapeutics, Inc. Methods for treating cancer and non-neoplastic conditions
US20120202801A1 (en) 2009-05-27 2012-08-09 Liangxian Cao Methods for treating breast cancer
US8658600B2 (en) 2009-06-26 2014-02-25 Brandeis University Antineoplastic hydrogels, and enzyme-instructed preparations thereof
AR077765A1 (es) 2009-07-21 2011-09-21 Gilead Sciences Inc Inhibidores de los virus flaviviridae
CA2768466C (en) 2009-07-22 2018-08-14 The Board Of Trustees Of The University Of Illinois Hdac inhibitors and therapeutic methods using the same
US8546523B2 (en) 2009-09-25 2013-10-01 Alcon Research, Ltd. NPR-B agonists
US8551938B2 (en) 2009-09-25 2013-10-08 Alcon Research, Ltd. NPR-B agonists
WO2011075471A2 (en) 2009-12-18 2011-06-23 Alcon Research, Ltd. Novel npr-b agonists and methods of use for the treatment of c-type natriuretic peptide-mediated disorders
EA021196B1 (ru) 2010-01-15 2015-04-30 Джилид Сайэнс, Инк. Ингибиторы вирусов flaviviridae
GB201013513D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
US9102712B2 (en) 2010-08-27 2015-08-11 New York University Dendrimeric peptides, pharmaceutical compositions and methods of using the same
EP2428503B1 (de) 2010-09-10 2014-12-10 Justus-Liebig-Universität Gießen Synthese von tripodalen Catecholderivaten mit einem flexiblen Grundgerüst zur Funktionalisierung von Oberflächen
WO2012122420A2 (en) 2011-03-09 2012-09-13 Pharmacofore, Inc. Opioid prodrugs with heterocyclic linkers
US9139612B2 (en) 2011-03-09 2015-09-22 Signature Therapeutics, Inc. Active agent prodrugs with heterocyclic linkers
EP2709650B1 (en) 2011-04-02 2017-02-08 Washington State University Hepatocyte growth factor mimics as therapeutic agents
US9051351B2 (en) * 2011-04-02 2015-06-09 Washington State University Hepatocyte growth factor mimics as therapeutic agents
CN102838523A (zh) 2011-06-23 2012-12-26 南开大学 抗肠病毒71(ev71)戊内酰胺类化合物及其制备方法和用途
GB201110938D0 (en) 2011-06-27 2011-08-10 Iti Scotland Ltd Compounds
BR112014004902B1 (pt) 2011-08-30 2022-02-08 United Kingdom Research And Innovation Peptídeo, composição farmacêutica ou medicamento compreendendo o dito peptídeo e uso do mesmo para tratar distrofia muscular de duchenne
EP2771319B1 (en) 2011-10-27 2022-03-02 Massachusetts Institute of Technology Amino acid derivatives functionalized on the n- terminal capable of forming drug incapsulating microspheres
KR20140132367A (ko) 2012-02-16 2014-11-17 알큐엑스 파마슈티컬스, 인크. 선형 펩티드 항생제
WO2013128003A1 (en) 2012-03-01 2013-09-06 Novo Nordisk A/S N-terminally modified oligopeptides and uses thereof
US20140094413A1 (en) * 2012-04-02 2014-04-03 Washington State University Hepatocyte growth factor (hgf) mimics as therapeutic agents
IN2014KN02410A (pl) 2012-04-05 2015-05-01 Vertex Pharma
JO3109B1 (ar) 2012-05-10 2017-09-20 Ferring Bv منبهات لمستقبلات v1a
CN104583194A (zh) 2012-05-11 2015-04-29 艾伯维公司 作为nampt抑制剂的哒嗪和吡啶衍生物
EP2852585A1 (en) 2012-05-11 2015-04-01 AbbVie Inc. Nampt inhibitors
WO2013190520A2 (en) 2012-06-22 2013-12-27 The General Hospital Corporation Gh-releasing agents in the treatment of vascular stenosis and associated conditions
AR092873A1 (es) 2012-09-26 2015-05-06 Cadila Healthcare Ltd Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon
EP2914734A1 (en) 2012-11-01 2015-09-09 Evonik Degussa GmbH Process for the enzymatic formation of amide bonds
US20150306232A1 (en) 2012-11-08 2015-10-29 Brandeis University Hydrogelators comprising d-amino acids
UA111925C2 (uk) 2012-12-11 2016-06-24 Федора Фармасьютікалз Інк. БІЦИКЛІЧНІ СПОЛУКИ ТА ЇХ ВИКОРИСТАННЯ ЯК АНТИБАКТЕРІАЛЬНИХ АГЕНТІВ ТА ІНГІБІТОРІВ β-ЛАКТАМАЗИ
EP2746262A1 (en) 2012-12-19 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds for combating phytopathogenic fungi
US8957078B2 (en) 2013-03-15 2015-02-17 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
HK1222864A1 (zh) 2013-03-15 2017-07-14 阿达拉塔合夥有限公司 Pcsk9的小分子调节剂和其使用方法
KR102306490B1 (ko) 2013-03-15 2021-09-28 리제너론 파아마슈티컬스, 인크. 생물학적 활성 분자, 그의 접합체 및 치료 용도
CA2911914A1 (en) 2013-05-08 2014-11-13 Board Of Regents, The University Of Texas System Stat6 inhibitors
US9221872B2 (en) 2013-06-24 2015-12-29 Canbas Co., Ltd. Peptides and peptidomimetics in combination uses and treatments for cancer patient subpopulations
EP3033352A4 (en) 2013-08-14 2017-04-19 RQX Pharmaceuticals, Inc. Linear peptide antibiotics
US10123960B2 (en) 2013-11-15 2018-11-13 Pcr Technology Holdings, Lc Methods for treating of skin conditions with retinoid double conjugate compounds
AU2014368591A1 (en) 2013-12-20 2016-07-07 Laboratorios Del Dr. Esteve S.A. Disabled Fused imidazolyl derivatives, their preparation and use as medicaments
JP6295702B2 (ja) 2014-02-14 2018-03-20 東洋インキScホールディングス株式会社 反応性単量体、およびそれを用いた重合性組成物
EP2910236B1 (de) 2014-02-24 2020-02-12 Ivoclar Vivadent AG Dentalmaterialien auf der Basis von geruchsarmen Thiolen
US20170191031A1 (en) 2014-04-30 2017-07-06 University Of Oslo Systems and methods for stem cell differentiation
CN105392498A (zh) 2014-05-15 2016-03-09 J制药股份有限公司 抗恶性肿瘤剂组合物
US9475854B2 (en) * 2014-05-23 2016-10-25 Washington State University Lead compound for otoprotection: targeting HGF signaling with dihexa
JP6158754B2 (ja) 2014-06-04 2017-07-05 信越化学工業株式会社 レジスト下層膜形成用組成物、及びパターン形成方法
EP3164476A1 (en) 2014-07-03 2017-05-10 Novozymes A/S Improved stabilization of non-protease enzyme
TWI515225B (zh) 2014-07-10 2016-01-01 國立交通大學 胜肽分子材料
EP2975046A1 (en) 2014-07-16 2016-01-20 The Provost, Fellows, Foundation Scholars, and The Other Members of Board, of The College of The Holy and Undivided Trinity of Queen Elizabeth Novel compounds
CN110938076B (zh) 2014-08-15 2021-08-10 正大天晴药业集团股份有限公司 作为tlr7激动剂的吡咯并嘧啶化合物
CN107001441A (zh) 2014-09-24 2017-08-01 印第安纳大学研究及科技有限公司 脂质化的基于酰胺的胰岛素前药
US9388214B2 (en) 2014-11-05 2016-07-12 Ferring B.V. V1A receptor agonists
WO2016097352A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Protease variants and polynucleotides encoding same
WO2016123576A1 (en) 2015-01-30 2016-08-04 Lieber Institute For Brain Development Comt inhibiting methods and compositions
RU2722363C2 (ru) 2015-03-11 2020-05-29 Чиа Тай Тяньцинь Фармасьютикал Груп Ко., Лтд. Замещенное производное 2н-пиразола
EA201791948A1 (ru) 2015-03-23 2018-04-30 Полифор Аг Бета-шпилечные пептидомиметики
CN104788537B (zh) 2015-03-31 2018-03-13 中国科学院长春应用化学研究所 一种四肽化合物及其制备方法和应用
MX2017013928A (es) 2015-05-01 2018-01-15 Ironwood Pharmaceuticals Inc Composiciones para limpieza de colon y tratamiento de trastornos gastrointestinales.
WO2016182898A1 (en) 2015-05-08 2016-11-17 Xenoport, Inc. Methods of use for monomethyl fumarate and prodrugs thereof
AU2016290654C1 (en) 2015-07-09 2021-11-11 Mimetogen Pharmaceuticals, Inc. Solution phase synthesis and crystallization of beta-turn peptidomimetic cyclic salts
US20170022149A1 (en) 2015-07-25 2017-01-26 Mark Quang Nguyen Fumarate compounds, pharmaceutical compositions thereof, and methods of use
RU2747581C2 (ru) 2015-12-18 2021-05-11 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Конъюгированные иммуноглобулины с c-концевым лизином
MX2018008321A (es) 2016-01-11 2018-09-21 Syndevrx Inc Tratamiento de tumores ocasionados por disfuncion metabolica.
WO2017129331A1 (en) 2016-01-28 2017-08-03 Novozymes A/S Method for cleaning a medical or dental instrument
WO2017151587A1 (en) 2016-02-29 2017-09-08 Ohio State Innovation Foundation Aza-peptide aldehydes and ketones
US20190022165A1 (en) 2016-03-02 2019-01-24 Stealth Biotherapeutics Corp Methods and compositions for the treatment and prevention of pulmonary arterial hypertension
US20190083574A1 (en) 2016-03-29 2019-03-21 Ohio State Innovation Foundation Thermogenic compositions and methods
EP3442955B1 (en) 2016-04-14 2021-09-29 The United States of America, as represented by the Secretary, Department of Health and Human Services Selective d3 dopamine receptor agonists and methods of their use
WO2017201433A1 (en) 2016-05-19 2017-11-23 Stealth Biotherapeutics Corp Compositions and methods for the prevention and treatment of mitochondrial myopathies
WO2017210188A1 (en) 2016-05-31 2017-12-07 Novozymes A/S Stabilized liquid peroxide compositions
CN116655730A (zh) 2016-06-01 2023-08-29 雅斯娜 用于治疗多种疾病的n-己酸-l-酪氨酸-l-异亮氨酸-(6)-氨基己酰胺的衍生物
BR112018076309A8 (pt) 2016-06-17 2022-06-28 Univ Erasmus Med Ct Rotterdam Compostos de geminóide e seus usos
US10398760B2 (en) 2016-06-30 2019-09-03 Gabriel Rusanescu Method of treating pain using agents that promote neuronal differentiation
AU2017297550B2 (en) 2016-07-12 2019-07-11 Guangdong Raynovent Biotech Co., Ltd. Pyrrolidine derivative serving as PPAR agonist
JP6883882B2 (ja) 2016-07-22 2021-06-09 シージャーズォアン サガシティ ニュー ドラッグ デベロップメント カンパニー リミテッド S1p1アゴニスト及びその応用
US9611297B1 (en) 2016-08-26 2017-04-04 Thrasos Therapeutics Inc. Compositions and methods for the treatment of cast nephropathy and related conditions
WO2018035615A1 (en) 2016-08-26 2018-03-01 Thrasos Therapeutics Inc. Compositions and methods for the treatment of inflammatory bowel diseases
WO2018035617A1 (en) 2016-08-26 2018-03-01 Thrasos Therapeutics Inc. Antibiotic carrier conjugates for the treatment of kidney infections
EP3512833B1 (en) 2016-09-15 2020-07-29 Boehringer Ingelheim International GmbH Heteroaryl carboxamide compounds as inhibitors of ripk2
EP3519548A1 (en) 2016-09-29 2019-08-07 Novozymes A/S Use of enzyme for washing, method for washing and warewashing composition
EP3342779A1 (en) 2016-12-27 2018-07-04 Zedira GmbH Inhibitors of transglutaminases
EP3345917B1 (en) 2017-01-05 2021-11-17 Bacoba AG Antiprotozoal compounds
AU2018210174B2 (en) 2017-01-18 2022-04-07 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
CA3054089A1 (en) 2017-02-22 2018-08-30 Universite De Montreal Novel minor histocompatibility antigens and uses thereof
WO2018174831A1 (en) 2017-03-24 2018-09-27 Agency For Science, Technology And Research Stapled peptides
US20200054622A1 (en) 2017-04-05 2020-02-20 Alkahest, Inc. Methods and Compositions for Treating Aging-Associated Impairments Using CCR3-Inhibitors
US10738082B2 (en) 2017-04-07 2020-08-11 University Of South Florida One-bead-two-compound macrocyclic library and methods of preparation and use
US20180340008A1 (en) 2017-05-24 2018-11-29 Bioxiness Pharmaceuticals, Inc. Antibiotic oligopeptide mimetics
CN108117582A (zh) 2017-12-30 2018-06-05 浙江大学 大环环氧酮肽类化合物及其制备方法和医药用途
JP2021513560A (ja) 2018-02-12 2021-05-27 ザ スクリップス リサーチ インスティテュートThe Scripps Research Institute パーキンソン病およびシヌクレイノパチーに関連する方法
KR20240038980A (ko) 2021-07-23 2024-03-26 아티라 파마, 인코포레이티드 파킨슨병 및/또는 루이체 질환 또는 장애(들)의 치료 방법

Also Published As

Publication number Publication date
JP2025020295A (ja) 2025-02-12
CY1125184T1 (el) 2024-12-13
CN116655730A (zh) 2023-08-29
ES2912035T3 (es) 2022-05-24
EP4067368A1 (en) 2022-10-05
AU2023285937A1 (en) 2024-01-25
LT3464336T (lt) 2022-05-10
AU2017273857B2 (en) 2021-08-19
CA3026074A1 (en) 2017-12-07
HRP20220479T1 (hr) 2022-05-27
SMT202200173T1 (it) 2022-05-12
JP2023036883A (ja) 2023-03-14
CN109563144A (zh) 2019-04-02
US20210340176A1 (en) 2021-11-04
JP2019525947A (ja) 2019-09-12
EP3464336A1 (en) 2019-04-10
RS63143B1 (sr) 2022-05-31
US20200010504A1 (en) 2020-01-09
EP3464336B1 (en) 2022-03-16
JP7203943B2 (ja) 2023-01-13
JP2022051738A (ja) 2022-04-01
US11021514B2 (en) 2021-06-01
WO2017210489A1 (en) 2017-12-07
CN116731101A (zh) 2023-09-12
DK3464336T3 (da) 2022-05-09
EP3464336A4 (en) 2020-01-15
SI3464336T1 (sl) 2022-06-30
AU2021266222A1 (en) 2021-12-02
CN109563144B (zh) 2023-03-28
AU2021266222B2 (en) 2023-10-05
US12421276B2 (en) 2025-09-23
AU2017273857A1 (en) 2018-12-20

Similar Documents

Publication Publication Date Title
GB201610147D0 (en) Novel compounds
GB201604647D0 (en) Novel compounds
GB201604638D0 (en) Novel compounds
GB201602854D0 (en) Novel compounds
GB201603779D0 (en) Novel compounds
GB201602934D0 (en) Compounds
GB201620119D0 (en) Compounds
GB201619694D0 (en) Compounds
GB201604027D0 (en) Compounds
GB201604020D0 (en) Compounds
SI3464336T1 (sl) Spojine
GB201610854D0 (en) Compounds
IL263228A (en) Benzoxaborole compounds
GB201608777D0 (en) Compounds
GB201613946D0 (en) Compounds
GB201604022D0 (en) Compounds
GB201604030D0 (en) Compounds
GB201713217D0 (en) Compounds
GB201621520D0 (en) Compounds
GB201622362D0 (en) Compounds
GB201604029D0 (en) Compounds
GB201601301D0 (en) Novel compounds
GB201622365D0 (en) Compounds
GB201604031D0 (en) Compounds
GB201600899D0 (en) Intermediate compounds