LT3464336T - Junginiai - Google Patents

Junginiai

Info

Publication number
LT3464336T
LT3464336T LTEPPCT/US2017/035547T LTUS2017035547T LT3464336T LT 3464336 T LT3464336 T LT 3464336T LT US2017035547 T LTUS2017035547 T LT US2017035547T LT 3464336 T LT3464336 T LT 3464336T
Authority
LT
Lithuania
Prior art keywords
compounds
Prior art date
Application number
LTEPPCT/US2017/035547T
Other languages
English (en)
Inventor
Leen Kawas
Jasbir Singh
Lansing Joseph Stewart
William Baker
Original Assignee
Athira Pharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Athira Pharma, Inc. filed Critical Athira Pharma, Inc.
Publication of LT3464336T publication Critical patent/LT3464336T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0217—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -C(=O)-C-N-C(=O)-N-C-C(=O)-
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LTEPPCT/US2017/035547T 2016-06-01 2017-06-01 Junginiai LT3464336T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662344305P 2016-06-01 2016-06-01
PCT/US2017/035547 WO2017210489A1 (en) 2016-06-01 2017-06-01 Compounds

Publications (1)

Publication Number Publication Date
LT3464336T true LT3464336T (lt) 2022-05-10

Family

ID=60478958

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2017/035547T LT3464336T (lt) 2016-06-01 2017-06-01 Junginiai

Country Status (16)

Country Link
US (2) US11021514B2 (lt)
EP (2) EP3464336B1 (lt)
JP (4) JP2019525947A (lt)
CN (3) CN109563144B (lt)
AU (3) AU2017273857B2 (lt)
CA (1) CA3026074A1 (lt)
CY (1) CY1125184T1 (lt)
DK (1) DK3464336T3 (lt)
ES (1) ES2912035T3 (lt)
HR (1) HRP20220479T1 (lt)
LT (1) LT3464336T (lt)
PL (1) PL3464336T3 (lt)
RS (1) RS63143B1 (lt)
SI (1) SI3464336T1 (lt)
SM (1) SMT202200173T1 (lt)
WO (1) WO2017210489A1 (lt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3464336T (lt) 2016-06-01 2022-05-10 Athira Pharma, Inc. Junginiai
MX2021003724A (es) * 2018-09-29 2021-05-14 Jiangsu Yahong Meditech Co Ltd Profarmaco de nitroxolina y su uso.
JP2024524679A (ja) * 2021-07-16 2024-07-05 アティラ・ファーマ・インコーポレイテッド アルツハイマー病の処置方法
KR20240038980A (ko) * 2021-07-23 2024-03-26 아티라 파마, 인코포레이티드 파킨슨병 및/또는 루이체 질환 또는 장애(들)의 치료 방법
TW202402284A (zh) 2022-05-04 2024-01-16 美商雅斯娜製藥公司 治療神經病變之方法
US20250275976A1 (en) 2022-05-04 2025-09-04 Athira Pharma, Inc. Methods of Treating Neuroinflammatory Conditions
WO2023215378A1 (en) 2022-05-04 2023-11-09 Athira Pharma, Inc. Methods of treating fibrosis
CN114907288B (zh) * 2022-05-13 2023-12-08 中国医学科学院医药生物技术研究所 硝基苯类化合物在制备铜绿假单胞菌群体感应抑制剂中的应用
WO2024108090A1 (en) 2022-11-18 2024-05-23 Athira Pharma, Inc. Methods of treating inflammatory conditions
EP4698277A1 (en) 2023-04-18 2026-02-25 Assia Chemical Industries Ltd. Solid state forms of fosgonimeton and salts thereof

Family Cites Families (243)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639456A (en) 1980-06-10 1987-01-27 Omnichem S.A. Vinblastin-23-oyl amino acid derivatives
GB8311286D0 (en) 1983-04-26 1983-06-02 Searle & Co Carboxyalkyl peptide derivatives
DE3320175A1 (de) 1983-06-03 1984-12-06 Boehringer Mannheim Gmbh, 6800 Mannheim Aminosaeure- bzw. peptidderivate, verfahren zu deren herstellung und verwendung als arzneimittel
US4477440A (en) 1983-09-14 1984-10-16 Merck & Co., Inc. Renin inhibitors containing an n-terminal disulfide cycle
EP0163237A3 (en) 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
EP0258289A4 (en) 1986-01-16 1991-01-02 Joseph Dellaria Peptide analogs
US5378691A (en) 1988-04-14 1995-01-03 Merck Patent Gesellschaft Mit Beschrankter Haftung Amino acid derivatives
JPH04500202A (ja) 1988-08-19 1992-01-16 ジ・アップジョン・カンパニー スレプタン酸またはその誘導体類を含有するレニン抑制ペプチド類
US5180816A (en) 1988-08-24 1993-01-19 Centocor One vial method for labeling protein/linker conjugates with technetium-99M
WO1990005531A1 (en) 1988-11-21 1990-05-31 Abbott Laboratories Method for treating vascular diseases
DE3912829A1 (de) 1989-04-19 1990-10-25 Bayer Ag Verwendung von renininhibitorischen peptiden als mittel gegen retroviren
DE4004820A1 (de) 1989-08-05 1991-04-25 Bayer Ag Renininhibitoren, verfahren zur herstellung und ihre verwendung in arzneimitteln
DE3915361A1 (de) 1989-05-11 1990-11-15 Merck Patent Gmbh Cyclopeptide
US5240913A (en) 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
CA2035917C (en) 1990-02-13 2001-10-02 John L. Krstenansky Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin
US5284828A (en) 1990-05-14 1994-02-08 Fujisawa Pharmaceutical Co. Ltd. Peptide compound and its preparation
AU648140B2 (en) 1991-02-01 1994-04-14 Virtual Drug Development, Inc. Reverse antimicrobial peptides and antimicrobial compositions
US5190924A (en) 1991-02-13 1993-03-02 Boc Health Care, Inc. Peptide amides and amide dimers useful as muscle relaxants
EP0584290B1 (en) 1991-05-16 2000-08-30 Warner-Lambert Company Endothelin antagonists
US5382569A (en) 1991-05-16 1995-01-17 Warner-Lambert Company Endotherlin antagonists
US5190922A (en) 1991-06-04 1993-03-02 Abbott Laboratories Terminally modified tri-, tetra- and pentapeptide anaphylatoxin receptor ligands
EP0519748B1 (en) 1991-06-21 1998-09-02 Merck & Co. Inc. Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme
DE4122885A1 (de) 1991-07-11 1993-01-21 Hoechst Ag Verfahren zur diastereoselektiven reduktiven pinakol-kupplung von homochiralen (alpha)-aminoaldehyden
US6348570B1 (en) 1991-08-16 2002-02-19 Merck & Co., Inc. Chromophore containing compounds and their use in determining interleukin-1β convertase activity
EP0533226A3 (en) 1991-08-16 1993-08-18 Merck & Co. Inc. Novel chromophore containing compounds
JPH05117169A (ja) 1991-10-29 1993-05-14 Mitsubishi Kasei Corp クロロメチルケトンの製法
US5227401A (en) 1991-10-29 1993-07-13 G. D. Searle & Co. Ethynyl alanine amino diol compounds for treatment of hypertension
US5223535A (en) 1991-10-29 1993-06-29 G. D. Searle & Co. Propargyl glycine amino propargyl diol compounds for treatment of hypertension
AU1339092A (en) 1991-12-13 1993-07-19 Corvas International, Inc. Reagents for automated synthesis of peptide analogs
EP0547699A1 (en) 1991-12-19 1993-06-23 Merck & Co. Inc. Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme
JPH05178890A (ja) 1991-12-26 1993-07-20 Banyu Pharmaceut Co Ltd エンドセリン拮抗性化合物
AU3479593A (en) 1992-01-31 1993-09-01 Merck & Co., Inc. Peptidyl derivatives as inhibitors of interleukin-1beta converting enzyme
DE69320176T2 (de) 1992-02-21 1999-04-08 Merck & Co., Inc., Rahway, N.J. Peptidylderivate und inhibitoren des interleukin-1-g(b)-konvertierenden enzyms
US5430062A (en) 1992-05-21 1995-07-04 Research Corporation Technologies, Inc. Stilbene derivatives as anticancer agents
EP0641301A1 (en) 1992-05-21 1995-03-08 Research Corporation Technologies, Inc. Stilbene derivatives as anticancer agents
EP0647239A4 (en) 1992-06-24 1997-07-02 Univ Washington ANGIOTENSIN IV PEPTIDES, AND RECEPTOR.
DE69332524T2 (de) 1992-09-24 2003-04-24 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Synthese von N-substituierten Oligomeren
EP0600832A1 (de) 1992-11-27 1994-06-08 Ciba-Geigy Ag Diaminobenzoe- und Diaminophthalsäurederivate und ihre Verfahren als Proteinkinase-Inhibitoren
IL107719A0 (en) 1992-12-21 1994-02-27 Du Pont Imidazolones their manufacture and their use as herbicides
JPH06192199A (ja) 1992-12-25 1994-07-12 Mitsubishi Kasei Corp ケトン誘導体
WO1994022906A1 (en) 1993-03-26 1994-10-13 Warner-Lambert Company Inhibitors of endothelin converting enzyme
DE4311021A1 (de) 1993-03-31 1994-10-27 Diagnostikforschung Inst Bifunktionelle Chelatbildner, deren Technetium- und Rhenium-Komplexe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende radiopharmazeutische Mittel
WO1994028012A1 (en) 1993-05-28 1994-12-08 Warner-Lambert Company Hydroxamate inhibitors of endothelin converting enzyme
US5854388A (en) 1993-06-24 1998-12-29 Washington State University Research Foundation Angiotensin IV peptides and receptor
DE4321306A1 (de) 1993-06-26 1995-01-05 Sanol Arznei Schwarz Gmbh Disulfide
GB9323165D0 (en) 1993-11-10 1994-01-05 Chiros Ltd Compounds
DE4345062A1 (de) 1993-12-31 1995-07-13 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von Viruserkrankungen
US5686419A (en) 1994-01-21 1997-11-11 Georgia Tech Research Corp. Basic α-aminoalkylphosphonate derivatives
GB2292149A (en) 1994-08-09 1996-02-14 Ferring Res Ltd Peptide inhibitors of pro-interleukin-1beta converting enzyme
US20010046668A1 (en) 1994-10-21 2001-11-29 G.D. Searle & Co. Fluorescence polarization method for determining protease activity
US5831004A (en) 1994-10-27 1998-11-03 Affymax Technologies N.V. Inhibitors of metalloproteases, pharmaceutical compositions comprising same and methods of their use
US5840698A (en) 1994-10-27 1998-11-24 Affymax Technologies N.V. Inhibitors of collagenase-1 and stormelysin-I metalloproteases, pharmaceutical compositions comprising same and methods of their use
CA2200964A1 (en) 1994-11-24 1996-05-30 Takeda Chemical Industries, Ltd. Alpha-ketoamide derivatives as cathepsin l inhibitor
EP0731107A1 (en) 1995-02-13 1996-09-11 Takeda Chemical Industries, Ltd. Production of aldehyde derivatives
JPH08262673A (ja) 1995-03-22 1996-10-11 Fuji Photo Film Co Ltd 銀塩拡散転写法による画像形成方法
US5798442A (en) 1995-04-21 1998-08-25 Merck Frosst Canada, Inc. Peptidyl derivatives as inhibitors of pro-apoptotic cysteine proteinases
WO1996033268A1 (en) 1995-04-21 1996-10-24 Merck & Co., Inc. Apopain
EP0838471A4 (en) 1995-07-07 2000-07-26 Sagami Chem Res PEPTIDE DERIVATIVES AND AGONISTS OF THE ANGIOTENSIN IV RECEPTOR
GB9517060D0 (en) * 1995-08-17 1995-10-25 Ciba Geigy Ag Acylated oligopeptide derivatives
US5763576A (en) 1995-10-06 1998-06-09 Georgia Tech Research Corp. Tetrapeptide α-ketoamides
WO1997016410A1 (en) 1995-10-30 1997-05-09 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5817757A (en) 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
US6121489A (en) 1996-03-05 2000-09-19 Trega Biosciences, Inc. Selectively N-alkylated peptidomimetic combinatorial libraries and compounds therein
EP0910579A1 (en) 1996-04-19 1999-04-28 Novo Nordisk A/S Compounds with growth hormone releasing properties
SE9603461D0 (sv) 1996-09-23 1996-09-23 Astra Ab New compounds
SE9603468D0 (sv) 1996-09-23 1996-09-23 Astra Ab New compounds
GB9623908D0 (en) 1996-11-18 1997-01-08 Hoffmann La Roche Amino acid derivatives
SI9600371B (sl) 1996-12-18 2005-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Etilidenski derivati tricikličnih karbapenemov
DE69728164D1 (de) 1996-12-27 2004-04-22 Boehringer Ingelheim Ca Ltd Peptidomimetische inhibitoren von der protease des menschlichen cytomegalovirus
GB2324529A (en) 1997-02-21 1998-10-28 Merck & Co Inc A combinatorial library based on a tetrapeptide substituted with aminomethylcoumarin for characterizing proteases
EP1038864A1 (en) 1997-12-12 2000-09-27 Fuji Yakuhin Kogyo Kabushiki Kaisha Novel metalloproteinase inhibitors
CA2225325A1 (en) 1997-12-19 1999-06-19 The University Of British Columbia Hemiasterlin analogs
US6468977B1 (en) 1998-03-02 2002-10-22 Apotex Inc. Thiadiazole compounds useful as inhibitors of cysteine activity dependent enzymes
GB9806815D0 (en) 1998-03-30 1998-05-27 Hoffmann La Roche Amino acid derivatives
US6022696A (en) 1998-04-02 2000-02-08 Washington State University Research Foundation Methods of identifying agonists or antagonists of angiotensin IV
GB9809664D0 (en) 1998-05-06 1998-07-01 Hoffmann La Roche a-Ketoamide derivatives
US6242563B1 (en) 1998-07-20 2001-06-05 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Peptide analogues
CA2335341A1 (en) 1998-07-20 2000-02-03 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R Peptide analogues of pacap
US6140342A (en) 1998-09-17 2000-10-31 Pfizer Inc. Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines
GB9828074D0 (en) * 1998-12-18 1999-02-17 Glaxo Group Ltd Therapeutically useful compounds
JP2000250182A (ja) 1999-03-04 2000-09-14 Fuji Photo Film Co Ltd カラー拡散転写写真画像形成方法
EP1059302A1 (en) 1999-06-08 2000-12-13 Aventis Pharma Deutschland GmbH Factor VIIa inhibitors
DE19947154A1 (de) 1999-10-01 2001-10-04 Bayer Ag Substituierte 2-Thio-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung
US20060233748A1 (en) 2002-09-13 2006-10-19 Ahmed Merzouk Mimetics of interleukin-8 and methods of using them in the prevention, treatment, diagnosis, and ameliorization of symptoms of a disease
US20070160574A1 (en) 2000-04-12 2007-07-12 Ahmed Merzouk Design of CXC chemokine analogs for the treatment of human diseases
US20070116669A1 (en) 2002-09-13 2007-05-24 Chemokine Therapeutics Corporation Interferon-inducible protein-10 (IP-10 or CXCL10) chemokine analogs for the treatment of human diseases
EP1275657A4 (en) 2000-04-14 2006-06-28 Nippon Shinyaku Co Ltd PEPTIDE DERIVATIVES AND MEDICINAL COMPOSITIONS
JP2002145898A (ja) 2000-11-09 2002-05-22 Ajinomoto Co Inc 新規グリチルレチン酸誘導体及び甘味剤
FR2816509B1 (fr) 2000-11-15 2004-02-06 Sod Conseils Rech Applic Association d'inhibiteurs de calpaine et de piegeurs des formes reactives de l'oxygene
JP2003040784A (ja) 2001-01-31 2003-02-13 Japan Science & Technology Corp 血糖降下剤
CA2444637A1 (en) 2001-01-16 2002-07-18 Ramot University Authority For Applied Research & Industrial Development Ltd. Hybrid peptides for treatment of bacteremia and septicemia
JP2005518332A (ja) 2001-05-23 2005-06-23 デンドレオン コーポレイション 細胞表面のプロテアーゼにより活性化される結合体およびその治療的使用
TW200301079A (en) 2001-12-21 2003-07-01 Syngenta Participations Ag Avermectin B1 derivatives having an aminosulfonyloxy substituent in the 4"-position
AU2003208105C1 (en) 2002-02-07 2009-08-13 J-Pharma Co., Ltd. Aromatic amino acid derivatives and medicinal compositions
US20040001801A1 (en) 2002-05-23 2004-01-01 Corvas International, Inc. Conjugates activated by cell surface proteases and therapeutic uses thereof
US7056947B2 (en) 2002-07-05 2006-06-06 Georgia Tech Research Corp. Aza-peptide epoxides
US8013014B2 (en) 2002-07-05 2011-09-06 Georgia Tech Research Corporation Aza-peptide epoxides
AU2003248888A1 (en) 2002-07-09 2004-01-23 Palatin Technologies, Inc. Peptide composition for treatment of sexual dysfunction
US7858737B2 (en) 2002-08-26 2010-12-28 Wisconsin Alumni Research Foundation Heterogeneous foldamers containing α, β, and/or γ-amino acids
US20050214859A1 (en) * 2003-03-03 2005-09-29 Dyax Corp. Peptides that specifically bind HGF receptor (cMet) and uses thereof
DE10320453A1 (de) 2003-05-08 2004-11-25 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Bioisostere von Actinonin
MXPA06000508A (es) 2003-07-18 2006-04-05 Amgen Inc Agentes de union especifica al factor del crecimiento de los hepatocitos.
CA2534355A1 (en) 2003-08-07 2005-02-17 Enkam Pharmaceuticals A/S Compounds comprising lpa
US7118747B2 (en) 2003-09-30 2006-10-10 Pacific Northwest Biotechnology Inc. AT4 receptor ligands as angiogenic, anti-angiogenic, and anti-tumor agents
SE0302853D0 (sv) 2003-10-29 2003-10-29 Astrazeneca Ab Chemical compounds
AU2005214388A1 (en) 2004-02-18 2005-09-01 Georgia Tech Research Corporation Propenoyl hydrazides
JP4502115B2 (ja) 2004-04-23 2010-07-14 信越化学工業株式会社 含窒素有機化合物、化学増幅型レジスト材料及びパターン形成方法
EP1740614A2 (en) 2004-04-30 2007-01-10 Theraptosis S.A. Caspase-2 inhibitors and their biological applications
WO2005113580A1 (en) 2004-05-21 2005-12-01 Pfizer Inc. Anticoronviral compounds and compositions, their pharmaceutical uses and materials for their synthesis
US20060063803A1 (en) 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7521427B2 (en) 2004-11-09 2009-04-21 Georgia Tech Research Corporation Peptidyl allyl sulfones
WO2006061714A2 (en) 2004-12-09 2006-06-15 Pfizer Inc. Anticoronaviral compounds and compositions, their pharmaceutical uses and materials for their synthesis
DE102005044319A1 (de) 2005-09-16 2007-03-22 Curacyte Chemistry Gmbh 2-(Aminomethyl)-5-Chlor-Benzylamid-Derivate und ihre Verwendung als Hemmstoffe des Gerinnungsfaktors Xa
US7790745B2 (en) 2005-10-21 2010-09-07 Bristol-Myers Squibb Company Tetrahydroisoquinoline LXR Modulators
GB0522061D0 (en) 2005-10-28 2005-12-07 Glaxo Group Ltd Chemical process
US7705009B2 (en) 2005-11-22 2010-04-27 Hoffman-La Roche Inc. 4-aminopyrimidine-5-thione derivatives
US20080090760A2 (en) 2005-12-09 2008-04-17 Todd Hembrough Compositions and Methods for Inhibiting Cellular Proliferation
JP5079265B2 (ja) 2006-06-13 2012-11-21 ポリプラスチックス株式会社 安定化ポリアセタール樹脂の製造方法
CN101466390B (zh) 2006-06-15 2014-03-12 优时比制药有限公司 用于治疗难治性癫痫持续状态的肽类化合物
EP1873527A1 (en) 2006-06-30 2008-01-02 Schwarz Pharma Ag Method for identifying CRMP modulators
ES2531118T5 (es) 2006-06-15 2022-06-14 Ucb Pharma Gmbh Composición farmacéutica que comprende lacosamida y levetiracetamo para uso en el tratamiento de la epilepsia
EP2046350A4 (en) 2006-06-22 2011-09-14 Biosurface Eng Tech Inc COMPOSITION AND METHOD FOR DELIVERING AMPLIFIER / CO-ACTIVATOR OF BMP-2 TO ENHANCE OSTEOGENESIS
US7910555B2 (en) 2006-07-07 2011-03-22 Washington State University Research Foundation C-Met receptor regulation by angiotensin IV (AT4 ) receptor ligands
US9066901B2 (en) 2006-07-07 2015-06-30 Washington State University C-Met receptor regulation by angiotensin IV (AT4) receptor ligands
US8236761B2 (en) 2006-07-07 2012-08-07 Washington State University Research Foundation C-Met receptor regulation by angiotensin IV (AT4) receptor ligands
WO2010094761A2 (en) 2009-02-20 2010-08-26 Dsm Ip Assets B.V. Oregano extract for alertness
EP1961765A1 (en) 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
ATE458749T1 (de) 2006-12-15 2010-03-15 Giuseppe Campiani Neuartige mit taxan verwandte peptide und deren verwendung
EP1977765A1 (en) 2007-04-03 2008-10-08 Diatos Peptide prodrugs
WO2009003003A2 (en) 2007-06-25 2008-12-31 Neurogen Corporation Piperazinyl oxoalkyl tetrahydro-beta-carbolines and related analogues
EP2173735B1 (en) 2007-07-02 2012-01-11 F. Hoffmann-La Roche AG Imidazole derivatives as ccr2 receptor antagonists
WO2009043747A2 (en) 2007-10-01 2009-04-09 F. Hoffmann-La Roche Ag N-heterocyclic biaryl carboxamides as ccr receptor antagonists
WO2009059002A2 (en) 2007-10-30 2009-05-07 The Regents Of The University Of Michigan Office Of Technology Transfer Macrocyclization of compounds from solid support using thioesterases
EP2083009A1 (de) 2008-01-22 2009-07-29 Grünenthal GmbH Substituierte Tethrahydroimidazopyridin-Verbindungen und deren Verwendung in Arzneimitteln
US9096649B2 (en) 2008-02-08 2015-08-04 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
EP2242503A4 (en) 2008-02-08 2012-04-25 Aileron Therapeutics Inc THERAPEUTIC PEPTIDOMIMETIC MACROCYCLES
US8673970B2 (en) 2008-02-21 2014-03-18 Sequoia Pharmaceuticals, Inc. HIV protease inhibitor and cytochrome p450 inhibitor combinations
KR101247840B1 (ko) 2008-02-22 2013-03-26 에프. 호프만-라 로슈 아게 아밀로이드 베타 조절제
WO2009114950A1 (en) 2008-03-21 2009-09-24 Chlorion Pharma, Inc. Substituted pyrrolidine and piperidine compounds, derivatives thereof, and methods for treating pain
US8367680B2 (en) 2008-03-28 2013-02-05 Wisconsin Alumni Research Foundation Antibacterial small molecules and methods for their synthesis
US8440827B2 (en) 2008-07-31 2013-05-14 Duke University Photolabile caged transition metal complexes and methods of using the same
US20110195900A1 (en) 2008-08-19 2011-08-11 Ferring B.V. Peptidic pth receptor agonists
WO2010039461A2 (en) 2008-10-03 2010-04-08 The Johns Hopkins University Methods for synthesis and uses of inhibitors of ghrelin o-acyltransferase as potential therapeutic agents for obesity and diabetes
ES2567455T3 (es) 2008-10-10 2016-04-22 Dara Biosciences, Inc. Nanoemulsiones que comprenden derivados de espicamicina para su uso en el tratamiento del dolor
CN102245624B (zh) 2008-12-19 2016-08-10 印第安纳大学研究及科技有限公司 基于酰胺的胰岛素前药
KR20110114568A (ko) 2008-12-19 2011-10-19 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 디펩티드 링크된 약효 물질
US8835602B2 (en) 2009-03-06 2014-09-16 Indian Institute Of Science Templates for nucleation and propagation of peptide secondary structure
US20120202801A1 (en) 2009-05-27 2012-08-09 Liangxian Cao Methods for treating breast cancer
WO2010138695A1 (en) 2009-05-27 2010-12-02 Ptc Therapeutics, Inc. Methods for treating neurofibromatosis
WO2010138659A1 (en) 2009-05-27 2010-12-02 Ptc Therapeutics, Inc. Methods for treating brain tumors
US8703726B2 (en) 2009-05-27 2014-04-22 Ptc Therapeutics, Inc. Methods for treating prostate conditions
MX373926B (es) 2009-05-27 2020-07-10 Ptc Therapeutics Inc Metodos para tratar cancer y estados no neoplasicos.
WO2010138652A1 (en) 2009-05-27 2010-12-02 Ptc Therapeutics, Inc. Methods for treating kaposi sarcoma
US8658600B2 (en) 2009-06-26 2014-02-25 Brandeis University Antineoplastic hydrogels, and enzyme-instructed preparations thereof
AU2010276441B2 (en) 2009-07-21 2015-07-02 Gilead Sciences, Inc. Inhibitors of Flaviviridae viruses
CA2768466C (en) 2009-07-22 2018-08-14 The Board Of Trustees Of The University Of Illinois Hdac inhibitors and therapeutic methods using the same
MX354005B (es) 2009-09-25 2018-02-08 Shire Orphan Therapies Gmbh Agonistas npr-b novedosos.
WO2011038066A2 (en) 2009-09-25 2011-03-31 Alcon Research, Ltd. Novel npr-b agonists
WO2011075471A2 (en) 2009-12-18 2011-06-23 Alcon Research, Ltd. Novel npr-b agonists and methods of use for the treatment of c-type natriuretic peptide-mediated disorders
AU2011205744B2 (en) 2010-01-15 2015-06-25 Gilead Sciences, Inc. Inhibitors of Flaviviridae viruses
GB201013513D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
WO2012026988A2 (en) 2010-08-27 2012-03-01 New York University Dendrimeric peptides, pharmaceutical compositions and methods of using the same
EP2428503B1 (de) 2010-09-10 2014-12-10 Justus-Liebig-Universität Gießen Synthese von tripodalen Catecholderivaten mit einem flexiblen Grundgerüst zur Funktionalisierung von Oberflächen
WO2012122420A2 (en) 2011-03-09 2012-09-13 Pharmacofore, Inc. Opioid prodrugs with heterocyclic linkers
BR112013022946A2 (pt) 2011-03-09 2017-07-18 Signature Therapeutics Inc pró-fármacos de agentes ativos com ligantes heterocíclocos
CA2832113C (en) * 2011-04-02 2020-07-21 Washington State University Research Foundation Hepatocyte growth factor mimics as therapeutic agents
US9051351B2 (en) * 2011-04-02 2015-06-09 Washington State University Hepatocyte growth factor mimics as therapeutic agents
CN102838523A (zh) 2011-06-23 2012-12-26 南开大学 抗肠病毒71(ev71)戊内酰胺类化合物及其制备方法和用途
GB201110938D0 (en) 2011-06-27 2011-08-10 Iti Scotland Ltd Compounds
WO2013030569A2 (en) 2011-08-30 2013-03-07 Michael John Gait Peptides
MX363734B (es) 2011-10-27 2019-03-29 Massachusetts Inst Technology Derivados de aminoacidos funcionalizados en la terminal n capaces de formar microesferas encapsuladoras de farmaco.
MX357561B (es) 2012-02-16 2018-07-13 Rqx Pharmaceuticals Inc Antibióticos peptídicos lineales.
US20150038435A1 (en) 2012-03-01 2015-02-05 Novo Nordisk A/S N-terminally modified oligopeptides and uses thereof
US20140094413A1 (en) * 2012-04-02 2014-04-03 Washington State University Hepatocyte growth factor (hgf) mimics as therapeutic agents
PT2833973T (pt) 2012-04-05 2017-12-21 Vertex Pharma Compostos úteis como inibidores da cinase atr e terapias de combinação dos mesmos
JO3109B1 (ar) 2012-05-10 2017-09-20 Ferring Bv منبهات لمستقبلات v1a
CN104583194A (zh) 2012-05-11 2015-04-29 艾伯维公司 作为nampt抑制剂的哒嗪和吡啶衍生物
WO2013170113A1 (en) 2012-05-11 2013-11-14 Abbvie Inc. Nampt inhibitors
WO2013190520A2 (en) 2012-06-22 2013-12-27 The General Hospital Corporation Gh-releasing agents in the treatment of vascular stenosis and associated conditions
AR092873A1 (es) 2012-09-26 2015-05-06 Cadila Healthcare Ltd Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon
DE112013005259T5 (de) 2012-11-01 2015-09-24 Evonik Degussa Gmbh Verfahren zur enzymatischen Bildung von Amidbindungen
WO2014074789A1 (en) 2012-11-08 2014-05-15 Brandeis University Hydrogelators comprising d-amino acids
UA111925C2 (uk) 2012-12-11 2016-06-24 Федора Фармасьютікалз Інк. БІЦИКЛІЧНІ СПОЛУКИ ТА ЇХ ВИКОРИСТАННЯ ЯК АНТИБАКТЕРІАЛЬНИХ АГЕНТІВ ТА ІНГІБІТОРІВ β-ЛАКТАМАЗИ
EP2746262A1 (en) 2012-12-19 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds for combating phytopathogenic fungi
EP2970289A1 (en) 2013-03-15 2016-01-20 Vertex Pharmaceuticals Inc. Compounds useful as inhibitors of atr kinase
KR20150132362A (ko) 2013-03-15 2015-11-25 에이다에레이타, 리미티드 파트너쉽 Pcsk9의 소분자 조절물질 및 그것의 사용 방법
AU2014233385C1 (en) 2013-03-15 2019-09-19 Regeneron Pharmaceuticals, Inc. Biologically active molecules, conjugates thereof, and therapeutic uses
US9765099B2 (en) 2013-05-08 2017-09-19 Board Of Regents, The University Of Texas System STAT6 inhibitors
CA2916136C (en) 2013-06-24 2022-10-18 Canbas Co., Ltd. Peptides and peptidomimetics in combination uses and treatments for cancer patient subpopulations
MX2016001927A (es) 2013-08-14 2016-09-08 Rqx Pharmaceuticals Inc Antibióticos de péptidos lineales.
WO2015073769A1 (en) 2013-11-15 2015-05-21 Us Cosmeceutechs Llc Retinoid double conjugate compounds, compositions thereof, and methods for treating of skin conditions
CN105916858B (zh) 2013-12-20 2018-09-14 埃斯特韦制药股份公司 稠合咪唑基衍生物、其制备和作为药物的用途
JP6295702B2 (ja) 2014-02-14 2018-03-20 東洋インキＳｃホールディングス株式会社 反応性単量体、およびそれを用いた重合性組成物
EP2910236B1 (de) 2014-02-24 2020-02-12 Ivoclar Vivadent AG Dentalmaterialien auf der Basis von geruchsarmen Thiolen
EP3137597A1 (en) 2014-04-30 2017-03-08 University Of Oslo Systems and methods for stem cell differentiation
KR20170001962A (ko) 2014-05-15 2017-01-06 제이 파마 가부시끼가이샤 항 악성 종양제 조성물
US9475854B2 (en) * 2014-05-23 2016-10-25 Washington State University Lead compound for otoprotection: targeting HGF signaling with dihexa
JP6158754B2 (ja) 2014-06-04 2017-07-05 信越化学工業株式会社 レジスト下層膜形成用組成物、及びパターン形成方法
US20170121646A1 (en) 2014-07-03 2017-05-04 Novozymes A/S Improved Stabilization of Non-Protease Enzyme
TWI515225B (zh) 2014-07-10 2016-01-01 國立交通大學 胜肽分子材料
EP2975046A1 (en) 2014-07-16 2016-01-20 The Provost, Fellows, Foundation Scholars, and The Other Members of Board, of The College of The Holy and Undivided Trinity of Queen Elizabeth Novel compounds
LT3190113T (lt) 2014-08-15 2021-08-25 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Pirolopirimidino junginiai, naudotini kaip tlr7 agonistai
EP3197912B1 (en) 2014-09-24 2023-01-04 Indiana University Research & Technology Corporation Lipidated amide-based insulin prodrugs
US9388214B2 (en) 2014-11-05 2016-07-12 Ferring B.V. V1A receptor agonists
DK3234093T3 (da) 2014-12-19 2020-08-17 Novozymes As Proteasevarianter og polynukleotider, som koder for dem
JP6858712B2 (ja) 2015-01-30 2021-04-14 リーバー インスティテュート フォー ブレイン ディベロップメントＬｉｅｂｅｒ Ｉｎｓｔｉｔｕｔｅ Ｆｏｒ Ｂｒａｉｎ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏｍｔ阻害方法及び組成物
BR112017019286B1 (pt) 2015-03-11 2023-02-14 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Derivados de 2h-pirazol substituídos ou um sal farmacêuticamente aceitável dos mesmos
EP3274361A1 (en) 2015-03-23 2018-01-31 Polyphor Ag Beta-hairpin peptidomimetics
CN104788537B (zh) 2015-03-31 2018-03-13 中国科学院长春应用化学研究所 一种四肽化合物及其制备方法和应用
WO2016178979A1 (en) 2015-05-01 2016-11-10 Ironwood Pharmaceuticals, Inc. Compositions for colon cleansing and the treatment of gastrointestinal disorders
WO2016182898A1 (en) 2015-05-08 2016-11-17 Xenoport, Inc. Methods of use for monomethyl fumarate and prodrugs thereof
EP4549450A3 (en) 2015-07-09 2025-07-02 Mimetogen Pharmaceuticals, Inc. Solution phase synthesis and crystallization of beta-turn peptidomimetic cyclic salts
US20170022149A1 (en) 2015-07-25 2017-01-26 Mark Quang Nguyen Fumarate compounds, pharmaceutical compositions thereof, and methods of use
ES2910699T3 (es) 2015-12-18 2022-05-13 Eisai R&D Man Co Ltd Inmunoglobulinas conjugadas con lisina C-terminal
EP3402529A1 (en) 2016-01-11 2018-11-21 Syndevrx, Inc. Treatment for tumors driven by metabolic dysfunction
ES2906780T3 (es) 2016-01-28 2022-04-20 Novozymes As Método de limpieza de un instrumento médico o dental
EP3423468A4 (en) 2016-02-29 2019-10-23 Ohio State Innovation Foundation AZA PEPTIDE ALDEHYDE AND KETONE
US20190022165A1 (en) 2016-03-02 2019-01-24 Stealth Biotherapeutics Corp Methods and compositions for the treatment and prevention of pulmonary arterial hypertension
US20190083574A1 (en) 2016-03-29 2019-03-21 Ohio State Innovation Foundation Thermogenic compositions and methods
EP3442955B1 (en) 2016-04-14 2021-09-29 The United States of America, as represented by the Secretary, Department of Health and Human Services Selective d3 dopamine receptor agonists and methods of their use
EP4000690A1 (en) 2016-05-19 2022-05-25 Stealth BioTherapeutics Inc. Compositions and methods for the prevention and treatment of mitochondrial myopathies
US20190218479A1 (en) 2016-05-31 2019-07-18 Novozymes A/S Stabilized Liquid Peroxide Compositions
LT3464336T (lt) 2016-06-01 2022-05-10 Athira Pharma, Inc. Junginiai
BR112018076309A8 (pt) 2016-06-17 2022-06-28 Univ Erasmus Med Ct Rotterdam Compostos de geminóide e seus usos
US10398760B2 (en) 2016-06-30 2019-09-03 Gabriel Rusanescu Method of treating pain using agents that promote neuronal differentiation
AU2017297550B2 (en) 2016-07-12 2019-07-11 Guangdong Raynovent Biotech Co., Ltd. Pyrrolidine derivative serving as PPAR agonist
EP3492465B1 (en) 2016-07-22 2021-03-24 Shijiazhuang Sagacity New Drug Development Co., Ltd. S1p1 agonist and application thereof
WO2018035617A1 (en) 2016-08-26 2018-03-01 Thrasos Therapeutics Inc. Antibiotic carrier conjugates for the treatment of kidney infections
WO2018035615A1 (en) 2016-08-26 2018-03-01 Thrasos Therapeutics Inc. Compositions and methods for the treatment of inflammatory bowel diseases
US9611297B1 (en) 2016-08-26 2017-04-04 Thrasos Therapeutics Inc. Compositions and methods for the treatment of cast nephropathy and related conditions
BR112019003320B1 (pt) 2016-09-15 2024-02-20 Boehringer Ingelheim International Gmbh Compostos de heteroaril carboxamida, sal farmaceuticamente aceitável dos mesmos, composição farmacêutica e seus usos como inibidores de ripk2
CN110023474A (zh) 2016-09-29 2019-07-16 诺维信公司 酶用于洗涤的用途、洗涤方法和器皿洗涤组合物
EP3342779A1 (en) 2016-12-27 2018-07-04 Zedira GmbH Inhibitors of transglutaminases
EP3345917B1 (en) 2017-01-05 2021-11-17 Bacoba AG Antiprotozoal compounds
WO2018136646A1 (en) 2017-01-18 2018-07-26 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
AU2018225825A1 (en) 2017-02-22 2019-09-12 Université de Montréal Novel minor histocompatibility antigens and uses thereof
WO2018174831A1 (en) 2017-03-24 2018-09-27 Agency For Science, Technology And Research Stapled peptides
US20200054622A1 (en) 2017-04-05 2020-02-20 Alkahest, Inc. Methods and Compositions for Treating Aging-Associated Impairments Using CCR3-Inhibitors
US10738082B2 (en) 2017-04-07 2020-08-11 University Of South Florida One-bead-two-compound macrocyclic library and methods of preparation and use
US20180340008A1 (en) 2017-05-24 2018-11-29 Bioxiness Pharmaceuticals, Inc. Antibiotic oligopeptide mimetics
CN108117582A (zh) 2017-12-30 2018-06-05 浙江大学 大环环氧酮肽类化合物及其制备方法和医药用途
US20210032369A1 (en) 2018-02-12 2021-02-04 The Scripps Research Institute Methods related to parkinson?s disease and synucleinopathies
KR20240038980A (ko) 2021-07-23 2024-03-26 아티라 파마, 인코포레이티드 파킨슨병 및/또는 루이체 질환 또는 장애(들)의 치료 방법

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