DK3672962T3 - Morpholinylpyridonforbindelser - Google Patents
Morpholinylpyridonforbindelser Download PDFInfo
- Publication number
- DK3672962T3 DK3672962T3 DK18759105.2T DK18759105T DK3672962T3 DK 3672962 T3 DK3672962 T3 DK 3672962T3 DK 18759105 T DK18759105 T DK 18759105T DK 3672962 T3 DK3672962 T3 DK 3672962T3
- Authority
- DK
- Denmark
- Prior art keywords
- morpholinylpyridone
- compounds
- morpholinylpyridone compounds
- Prior art date
Links
- NMVVTUFCOTZTMF-UHFFFAOYSA-N 3-morpholin-4-yl-1h-pyridin-2-one Chemical class O=C1NC=CC=C1N1CCOCC1 NMVVTUFCOTZTMF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17187567 | 2017-08-23 | ||
| PCT/EP2018/072791 WO2019038390A1 (en) | 2017-08-23 | 2018-08-23 | MORPHOLINYLPYRIDONE COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3672962T3 true DK3672962T3 (da) | 2022-05-02 |
Family
ID=59686888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18759105.2T DK3672962T3 (da) | 2017-08-23 | 2018-08-23 | Morpholinylpyridonforbindelser |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11560374B2 (da) |
| EP (2) | EP4056569A1 (da) |
| JP (2) | JP7199736B2 (da) |
| KR (1) | KR20200044025A (da) |
| CN (3) | CN111108102B (da) |
| AU (2) | AU2018320419B2 (da) |
| CA (1) | CA3073142A1 (da) |
| DK (1) | DK3672962T3 (da) |
| ES (1) | ES2910157T3 (da) |
| HR (1) | HRP20220497T1 (da) |
| HU (1) | HUE058661T2 (da) |
| IL (3) | IL302077A (da) |
| LT (1) | LT3672962T (da) |
| PL (1) | PL3672962T3 (da) |
| PT (1) | PT3672962T (da) |
| RS (1) | RS63109B1 (da) |
| SI (1) | SI3672962T1 (da) |
| TW (2) | TW202348601A (da) |
| WO (1) | WO2019038390A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117241829A (zh) * | 2020-11-25 | 2023-12-15 | 德西费拉制药有限责任公司 | Vps34抑制剂的抗病毒活性 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130130030A (ko) | 2010-12-21 | 2013-11-29 | 노파르티스 아게 | Vps34 억제제로서의 비-헤테로아릴 화합물 |
| DK2655375T3 (da) * | 2010-12-23 | 2015-03-09 | Sanofi Sa | Pyrimidinonderivater, fremstilling og farmaceutisk anvendelse heraf |
| GB201120317D0 (en) | 2011-11-24 | 2012-01-04 | Queen Mary & Westfield College | Screening method |
| FR2992314B1 (fr) | 2012-06-22 | 2015-10-16 | Sanofi Sa | Nouveaux derives de 2,3-dihydro-1h-imidazo{1,2-a}pyrimidin-5-one et 1,2,3,4-tetrahydro-pyrimido{1,2-a}pyrimidin-6-one comportant une morpholine substituee, leur preparation et leur utilisation pharmaceutique |
| JP6074043B2 (ja) * | 2013-08-29 | 2017-02-01 | 富士フイルム株式会社 | 新規なモルホリン誘導体またはその塩 |
| KR20160122736A (ko) | 2014-01-14 | 2016-10-24 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 헤테로아릴 및 이의 용도 |
| EP3094326A4 (en) | 2014-01-14 | 2017-07-26 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| MA39823A (fr) | 2014-04-03 | 2018-01-09 | Janssen Pharmaceutica Nv | Dérivés de pyridine macrocyclique |
| MA39822A (fr) | 2014-04-03 | 2018-02-06 | Janssen Pharmaceutica Nv | Dérivés de pyrimidine bicycle |
| WO2017009751A1 (en) | 2015-07-15 | 2017-01-19 | Pfizer Inc. | Pyrimidine derivatives |
| RS60900B1 (sr) * | 2016-02-19 | 2020-11-30 | Sprint Bioscience Ab | Jedinjenja 6-heterociklil-4-morfolin-4-ilpiridin-2-ona korisna za lečenje kancera i dijabetesa |
| SI3416945T1 (sl) | 2016-02-19 | 2020-11-30 | Sprint Bioscience Ab | Spojine 6-aril-4-(morfolin-4-IL)-1H-piridin-2-ona, uporabne za zdravljenje raka in diabetesa |
-
2018
- 2018-08-23 HU HUE18759105A patent/HUE058661T2/hu unknown
- 2018-08-23 HR HRP20220497TT patent/HRP20220497T1/hr unknown
- 2018-08-23 EP EP22153292.2A patent/EP4056569A1/en active Pending
- 2018-08-23 CN CN201880060742.XA patent/CN111108102B/zh active Active
- 2018-08-23 IL IL302077A patent/IL302077A/en unknown
- 2018-08-23 CN CN202310448700.6A patent/CN116444510A/zh active Pending
- 2018-08-23 RS RS20220357A patent/RS63109B1/sr unknown
- 2018-08-23 PL PL18759105T patent/PL3672962T3/pl unknown
- 2018-08-23 SI SI201830624T patent/SI3672962T1/sl unknown
- 2018-08-23 WO PCT/EP2018/072791 patent/WO2019038390A1/en unknown
- 2018-08-23 TW TW112116474A patent/TW202348601A/zh unknown
- 2018-08-23 AU AU2018320419A patent/AU2018320419B2/en active Active
- 2018-08-23 LT LTEPPCT/EP2018/072791T patent/LT3672962T/lt unknown
- 2018-08-23 CN CN202310448740.0A patent/CN116462674A/zh active Pending
- 2018-08-23 PT PT187591052T patent/PT3672962T/pt unknown
- 2018-08-23 EP EP18759105.2A patent/EP3672962B1/en active Active
- 2018-08-23 TW TW107129499A patent/TWI803511B/zh active
- 2018-08-23 ES ES18759105T patent/ES2910157T3/es active Active
- 2018-08-23 US US16/639,902 patent/US11560374B2/en active Active
- 2018-08-23 KR KR1020207007564A patent/KR20200044025A/ko not_active Application Discontinuation
- 2018-08-23 JP JP2020510087A patent/JP7199736B2/ja active Active
- 2018-08-23 CA CA3073142A patent/CA3073142A1/en active Pending
- 2018-08-23 DK DK18759105.2T patent/DK3672962T3/da active
-
2020
- 2020-02-20 IL IL272815A patent/IL272815B/en unknown
-
2022
- 2022-04-25 IL IL292489A patent/IL292489B2/en unknown
- 2022-12-13 JP JP2022198452A patent/JP2023021268A/ja active Pending
- 2022-12-19 US US18/084,208 patent/US20230234949A1/en active Pending
-
2023
- 2023-12-22 AU AU2023285995A patent/AU2023285995A1/en not_active Abandoned
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