PL2041276T3 - Sposób wytwarzania L-aminokwasów za pomocą mutantów genu gltA kodującego syntazę cytranianową - Google Patents

Sposób wytwarzania L-aminokwasów za pomocą mutantów genu gltA kodującego syntazę cytranianową

Info

Publication number
PL2041276T3
PL2041276T3 PL07786778T PL07786778T PL2041276T3 PL 2041276 T3 PL2041276 T3 PL 2041276T3 PL 07786778 T PL07786778 T PL 07786778T PL 07786778 T PL07786778 T PL 07786778T PL 2041276 T3 PL2041276 T3 PL 2041276T3
Authority
PL
Poland
Prior art keywords
amino acid
producing
amino acids
citrate synthase
mutants
Prior art date
Application number
PL07786778T
Other languages
English (en)
Inventor
Brigitte Bathe
Wilfried Claes
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of PL2041276T3 publication Critical patent/PL2041276T3/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/03Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/03001Citrate (Si)-synthase (2.3.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02004Aspartate kinase (2.7.2.4)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
PL07786778T 2006-07-13 2007-06-20 Sposób wytwarzania L-aminokwasów za pomocą mutantów genu gltA kodującego syntazę cytranianową PL2041276T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006032634A DE102006032634A1 (de) 2006-07-13 2006-07-13 Verfahren zur Herstellung von L-Aminosäuren
EP07786778A EP2041276B1 (de) 2006-07-13 2007-06-20 Verfahren zur herstellung von l-aminosäuren mittels mutanten des glta-gens kodierend für citratsynthase
PCT/EP2007/056153 WO2008006680A2 (de) 2006-07-13 2007-06-20 Verfahren zur herstellung von l-aminosäuren mittels mutanten des glta-gens kodierend für citratsynthase

Publications (1)

Publication Number Publication Date
PL2041276T3 true PL2041276T3 (pl) 2012-07-31

Family

ID=38825283

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07786778T PL2041276T3 (pl) 2006-07-13 2007-06-20 Sposób wytwarzania L-aminokwasów za pomocą mutantów genu gltA kodującego syntazę cytranianową

Country Status (8)

Country Link
US (3) US7785840B2 (pl)
EP (1) EP2041276B1 (pl)
AT (1) ATE547516T1 (pl)
DE (1) DE102006032634A1 (pl)
DK (1) DK2041276T3 (pl)
ES (1) ES2382363T3 (pl)
PL (1) PL2041276T3 (pl)
WO (1) WO2008006680A2 (pl)

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DK2865275T3 (da) * 2013-10-24 2020-05-18 Evonik Operations Gmbh Foderstofadditiv indeholdende L-aminosyre
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US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
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US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
DE102017004751A1 (de) * 2017-05-18 2018-11-22 Forschungszentrum Jülich GmbH Pyruvatcarboxylase und für die Pyruvatcarboxylase kodierende DNA, Plasmid enthaltend die DNA, sowie Mikroorganismus zur Produktion und verfahren zur Herstellung von Produkten, deren Bioynthese Oxalacetat als Vorstufe beeinhaltet und Chromosom
EP3746544A4 (en) 2018-02-01 2021-10-27 INVISTA Textiles (U.K.) Limited PROCESS AND MATERIALS FOR THE BIOSYNTHESIS OF COMPOUNDS INVOLVED IN THE TRICARBONIC ACID CYCLE AND THEIR DERIVATIVES AND COMPOUNDS
KR101915433B1 (ko) 2018-02-13 2018-11-05 씨제이제일제당 (주) 시트레이트 신타아제 (Citrate synthase)의 활성이 약화된 변이형 폴리펩타이드 및 이를 이용한 L-아미노산 생산방법
KR102205717B1 (ko) * 2019-04-05 2021-01-22 씨제이제일제당 주식회사 신규 l-트립토판 배출 단백질 변이체 및 이를 이용한 l-트립토판을 생산하는 방법
KR102285951B1 (ko) * 2020-01-30 2021-08-04 씨제이제일제당 주식회사 시트레이트 신타아제의 활성이 약화된 신규한 변이형 폴리펩티드 및 이를 이용한 l-아미노산 생산 방법
JP2023540518A (ja) * 2020-09-03 2023-09-25 デサン・コーポレイション L-リジン生産能が向上したコリネバクテリウムグルタミクム変異株およびこれを用いたl-リジンの生産方法
WO2022050524A1 (ko) * 2020-09-03 2022-03-10 대상 주식회사 L-라이신 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-라이신의 생산 방법
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KR102525072B1 (ko) * 2021-03-10 2023-04-24 씨제이제일제당 주식회사 신규한 시트레이트 신타아제 변이체 및 이를 이용한 l-아미노산 생산 방법
KR102525074B1 (ko) * 2021-03-10 2023-04-24 씨제이제일제당 주식회사 신규한 시트레이트 신타아제 변이체 및 이를 이용한 o-아세틸-l-호모세린 또는 l-메티오닌 생산 방법
KR102525073B1 (ko) * 2021-03-10 2023-04-24 씨제이제일제당 주식회사 신규한 시트레이트 신타아제 변이체 및 이를 이용한 l-발린 생산 방법
JP7683040B2 (ja) * 2021-04-29 2025-05-26 シージェイ チェイルジェダング コーポレイション L-リシン生産能が向上したコリネバクテリウム・グルタミカム変異株及びそれを用いたl-リシンの生産方法
CN113249347B (zh) * 2021-07-14 2021-11-12 中国科学院天津工业生物技术研究所 丙酮酸脱氢酶的突变体及其用于生产l-氨基酸的方法
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CN117327677B (zh) * 2023-09-26 2024-09-20 江南大学 天冬氨酸激酶突变体及其应用

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Also Published As

Publication number Publication date
ES2382363T3 (es) 2012-06-07
EP2041276B1 (de) 2012-02-29
DE102006032634A1 (de) 2008-01-17
ATE547516T1 (de) 2012-03-15
US8202706B2 (en) 2012-06-19
US7785840B2 (en) 2010-08-31
US20100261257A1 (en) 2010-10-14
WO2008006680A3 (de) 2008-07-03
WO2008006680A2 (de) 2008-01-17
EP2041276A2 (de) 2009-04-01
DK2041276T3 (da) 2012-05-29
US20080014618A1 (en) 2008-01-17
WO2008006680A8 (de) 2008-09-25
US20090280542A1 (en) 2009-11-12
US8119372B2 (en) 2012-02-21

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