PL117515B1 - Process for preparing novel,substituted aminothiazoles - Google Patents

Process for preparing novel,substituted aminothiazoles Download PDF

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Publication number
PL117515B1
PL117515B1 PL1979216030A PL21603079A PL117515B1 PL 117515 B1 PL117515 B1 PL 117515B1 PL 1979216030 A PL1979216030 A PL 1979216030A PL 21603079 A PL21603079 A PL 21603079A PL 117515 B1 PL117515 B1 PL 117515B1
Authority
PL
Poland
Prior art keywords
phenyl
group
formula
hydrogen
compounds
Prior art date
Application number
PL1979216030A
Other languages
English (en)
Polish (pl)
Other versions
PL216030A1 (cs
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PL216030A1 publication Critical patent/PL216030A1/xx
Publication of PL117515B1 publication Critical patent/PL117515B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16BDEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B15/00Nails; Staples
    • F16B15/0023Nail plates
    • F16B2015/0076Nail plates with provisions for additional fastening means, e.g. hooks, holes for separate screws or nails, adhesive

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL1979216030A 1978-06-02 1979-06-01 Process for preparing novel,substituted aminothiazoles PL117515B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91183078A 1978-06-02 1978-06-02

Publications (2)

Publication Number Publication Date
PL216030A1 PL216030A1 (cs) 1980-03-10
PL117515B1 true PL117515B1 (en) 1981-08-31

Family

ID=25430923

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1979216030A PL117515B1 (en) 1978-06-02 1979-06-01 Process for preparing novel,substituted aminothiazoles

Country Status (36)

Country Link
JP (1) JPS5936988B2 (cs)
AR (1) AR226285A1 (cs)
AT (1) AT373248B (cs)
AU (1) AU511242B2 (cs)
BE (1) BE876732A (cs)
CA (1) CA1117949A (cs)
CH (1) CH639653A5 (cs)
CS (1) CS216927B2 (cs)
DD (1) DD144055A5 (cs)
DE (1) DE2922523C2 (cs)
DK (1) DK150068C (cs)
EG (1) EG14354A (cs)
ES (1) ES481220A1 (cs)
FI (1) FI68820C (cs)
FR (1) FR2427333A1 (cs)
GB (1) GB2022085B (cs)
GR (1) GR73142B (cs)
HK (1) HK66487A (cs)
HU (1) HU180045B (cs)
IE (1) IE48426B1 (cs)
IL (1) IL57450A (cs)
IT (1) IT1121238B (cs)
KE (1) KE3459A (cs)
LU (1) LU81349A1 (cs)
MY (1) MY8500318A (cs)
NL (1) NL178421C (cs)
NO (1) NO150760C (cs)
NZ (1) NZ190623A (cs)
PH (1) PH17020A (cs)
PL (1) PL117515B1 (cs)
PT (1) PT69718A (cs)
SE (1) SE438333B (cs)
SG (1) SG56184G (cs)
SU (1) SU843746A3 (cs)
YU (1) YU40997B (cs)
ZA (1) ZA792729B (cs)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063575A4 (en) * 1980-10-24 1983-02-14 Ronald Peter Hansen DUST REDUCTION SYSTEM.
WO1982002384A1 (en) * 1981-01-08 1982-07-22 Sakano Isao Their preparation,and medicinal composition containing same
JPS57136579A (en) * 1981-01-21 1982-08-23 Mitsui Toatsu Chem Inc Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
JPS57116067A (en) * 1981-01-12 1982-07-19 Sankyo Kagaku Kk Novel 8-quinolinesulfonyl derivative, its synthesis and use
WO1982002383A1 (en) * 1981-01-13 1982-07-22 Sakano Isao Novel thiazole compounds,process for their preparation,and medicinal composition containing same
WO1982002386A1 (en) * 1981-01-13 1982-07-22 Sakano Isao Aminothiazole derivatives,process for their preparation,and medicinal composition containing same
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
DE3227329A1 (de) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2-n,n-disubstituierten aminothiazolen
WO1986003203A1 (fr) * 1984-11-22 1986-06-05 Yoshitomi Pharmaceutical Industries, Ltd. Derives de thienylthiazole
FR2581063B1 (fr) * 1985-04-30 1987-07-17 Chauvin Blache Lab Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique
JPS63152368A (ja) * 1986-06-03 1988-06-24 Sumitomo Pharmaceut Co Ltd 新規なアミノアゾ−ル誘導体およびその酸付加塩
JPH075579B2 (ja) * 1986-09-01 1995-01-25 吉富製薬株式会社 アミノチアゾ−ル化合物
JPH0753666B2 (ja) * 1987-09-14 1995-06-07 久光製薬株式会社 置換ジフェニルチアゾール誘導体からなる抗炎症剤
SG43845A1 (en) * 1989-08-10 1997-11-14 Commw Scient Ind Res Org Apparatus for production electrosuspensions
EP0592664B1 (en) * 1991-03-07 2000-07-05 Hisamitsu Pharmaceutical Co., Inc. Derivatives of diphenylthiazole with antiinflammatory activity
FR2692893B1 (fr) * 1992-06-24 1994-09-02 Sanofi Elf Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
AU3201095A (en) * 1994-07-27 1996-02-22 G.D. Searle & Co. Substituted thiazoles for the treatment of inflammation
FR2754258B1 (fr) 1996-10-08 1998-12-31 Sanofi Sa Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
US7105550B2 (en) * 2000-03-01 2006-09-12 Christopher Love 2,4-disubstituted thiazolyl derivatives
WO2003015777A1 (en) * 2001-08-13 2003-02-27 Lion Bioscience Ag Nr1h4 nuclear receptor binding compounds
WO2003027101A1 (en) * 2001-09-26 2003-04-03 Bayer Pharmaceuticals Corporation Substituted 3-pyridyl pyrroles and 3-pyridyl pyrazoles as c17,20 lyase inhibitors
AU2003202495B2 (en) 2002-01-11 2006-07-20 Sankyo Company, Limited Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
EP1555264A1 (en) * 2004-01-15 2005-07-20 Sireen AG Five-membered heterocyclic compounds as inhibitors of SRC family protein kinase.
KR20110136901A (ko) 2004-02-24 2011-12-21 상꾜 가부시키가이샤 아미노 알코올 화합물
MX2007013955A (es) * 2005-05-09 2008-02-05 Achillion Pharmaceuticals Inc Compuestos de tiazol y metodos de uso.
WO2007084391A2 (en) 2006-01-18 2007-07-26 Amgen Inc. Thiazole compounds as protein kinase b ( pkb) inhibitors
WO2009011871A2 (en) 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of pkb
WO2009011880A2 (en) 2007-07-17 2009-01-22 Amgen Inc. Heterocyclic modulators of pkb
US20130143927A1 (en) * 2011-06-10 2013-06-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2012170931A2 (en) 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2013059677A1 (en) 2011-10-19 2013-04-25 Calcimedica, Inc. Compounds that modulate intracellular calcium
CN110590785B (zh) * 2019-09-23 2021-02-02 武汉大学 一种氨基噻唑类化合物及其制备方法与抗肠道病毒71型的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458526A (en) * 1966-09-26 1969-07-29 Upjohn Co Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles

Also Published As

Publication number Publication date
FI791754A7 (fi) 1979-11-26
JPS5936988B2 (ja) 1984-09-06
EG14354A (en) 1984-06-30
HU180045B (en) 1983-01-28
ZA792729B (en) 1981-03-25
AR226285A1 (es) 1982-06-30
BE876732A (fr) 1979-12-03
ES481220A1 (es) 1980-09-01
AU511242B2 (en) 1980-08-07
NL178421C (nl) 1986-03-17
DK150068B (da) 1986-12-01
SG56184G (en) 1985-03-08
GR73142B (cs) 1984-02-09
FI68820B (fi) 1985-07-31
IE48426B1 (en) 1985-01-23
AT373248B (de) 1983-12-27
MY8500318A (en) 1985-12-31
GB2022085B (en) 1983-01-12
CH639653A5 (fr) 1983-11-30
DK150068C (da) 1987-06-29
DE2922523C2 (de) 1982-10-21
FR2427333A1 (fr) 1979-12-28
PT69718A (en) 1979-07-01
DE2922523A1 (de) 1979-12-06
YU40997B (en) 1986-10-31
IT7923228A0 (it) 1979-06-01
PL216030A1 (cs) 1980-03-10
NZ190623A (en) 1984-07-06
FI68820C (fi) 1985-11-11
SE438333B (sv) 1985-04-15
NO791831L (no) 1979-12-04
IL57450A (en) 1982-11-30
ATA401679A (de) 1983-05-15
NL178421B (nl) 1985-10-16
FR2427333B1 (cs) 1983-05-20
YU128879A (en) 1982-10-31
HK66487A (en) 1987-09-25
SE7904798L (sv) 1979-12-03
NL7904337A (nl) 1979-12-04
IT1121238B (it) 1986-03-26
DD144055A5 (de) 1980-09-24
KE3459A (en) 1984-10-12
NO150760C (no) 1984-12-12
SU843746A3 (ru) 1981-06-30
LU81349A1 (fr) 1979-12-07
IE791069L (en) 1979-12-02
NO150760B (no) 1984-09-03
PH17020A (en) 1984-05-11
GB2022085A (en) 1979-12-12
JPS54160369A (en) 1979-12-19
AU4763479A (en) 1979-12-06
CA1117949A (en) 1982-02-09
DK177679A (da) 1979-12-03
IL57450A0 (en) 1979-09-30
CS216927B2 (en) 1982-12-31

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