AT373248B - Verfahren zur herstellung neuer aminothiazole und deren salzen - Google Patents

Verfahren zur herstellung neuer aminothiazole und deren salzen

Info

Publication number
AT373248B
AT373248B AT0401679A AT401679A AT373248B AT 373248 B AT373248 B AT 373248B AT 0401679 A AT0401679 A AT 0401679A AT 401679 A AT401679 A AT 401679A AT 373248 B AT373248 B AT 373248B
Authority
AT
Austria
Prior art keywords
aminothiazoles
salts
producing new
producing
new
Prior art date
Application number
AT0401679A
Other languages
English (en)
Other versions
ATA401679A (de
Inventor
Joseph George Lombardino
Jasjit Singh Bindra
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ATA401679A publication Critical patent/ATA401679A/de
Application granted granted Critical
Publication of AT373248B publication Critical patent/AT373248B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16BDEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B15/00Nails; Staples
    • F16B15/0023Nail plates
    • F16B2015/0076Nail plates with provisions for additional fastening means, e.g. hooks, holes for separate screws or nails, adhesive
AT0401679A 1978-06-02 1979-06-01 Verfahren zur herstellung neuer aminothiazole und deren salzen AT373248B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91183078A 1978-06-02 1978-06-02

Publications (2)

Publication Number Publication Date
ATA401679A ATA401679A (de) 1983-05-15
AT373248B true AT373248B (de) 1983-12-27

Family

ID=25430923

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0401679A AT373248B (de) 1978-06-02 1979-06-01 Verfahren zur herstellung neuer aminothiazole und deren salzen

Country Status (36)

Country Link
JP (1) JPS5936988B2 (de)
AR (1) AR226285A1 (de)
AT (1) AT373248B (de)
AU (1) AU511242B2 (de)
BE (1) BE876732A (de)
CA (1) CA1117949A (de)
CH (1) CH639653A5 (de)
CS (1) CS216927B2 (de)
DD (1) DD144055A5 (de)
DE (1) DE2922523C2 (de)
DK (1) DK150068C (de)
EG (1) EG14354A (de)
ES (1) ES481220A1 (de)
FI (1) FI68820C (de)
FR (1) FR2427333A1 (de)
GB (1) GB2022085B (de)
GR (1) GR73142B (de)
HK (1) HK66487A (de)
HU (1) HU180045B (de)
IE (1) IE48426B1 (de)
IL (1) IL57450A (de)
IT (1) IT1121238B (de)
KE (1) KE3459A (de)
LU (1) LU81349A1 (de)
MY (1) MY8500318A (de)
NL (1) NL178421C (de)
NO (1) NO150760C (de)
NZ (1) NZ190623A (de)
PH (1) PH17020A (de)
PL (1) PL117515B1 (de)
PT (1) PT69718A (de)
SE (1) SE438333B (de)
SG (1) SG56184G (de)
SU (1) SU843746A3 (de)
YU (1) YU40997B (de)
ZA (1) ZA792729B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001481A1 (en) * 1980-10-24 1982-05-13 Ronald P Hansen Dust mitigation system
JPS57136579A (en) * 1981-01-21 1982-08-23 Mitsui Toatsu Chem Inc Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
EP0068033B1 (de) * 1981-01-08 1985-07-10 Mitsui Toatsu Kagaku Kabushiki Kaisha N-(4-phenyl-2-thiazolyl)karbamatabkömmlinge, verfahren zu deren herstellung und diese enthaltendes arzneimittel
JPS57116067A (en) * 1981-01-12 1982-07-19 Sankyo Kagaku Kk Novel 8-quinolinesulfonyl derivative, its synthesis and use
WO1982002386A1 (en) * 1981-01-13 1982-07-22 Sakano Isao Aminothiazole derivatives,process for their preparation,and medicinal composition containing same
WO1982002383A1 (en) * 1981-01-13 1982-07-22 Sakano Isao Novel thiazole compounds,process for their preparation,and medicinal composition containing same
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
DE3227329A1 (de) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2-n,n-disubstituierten aminothiazolen
WO1986003203A1 (en) * 1984-11-22 1986-06-05 Yoshitomi Pharmaceutical Industries, Ltd. Thienylthiazole derivatives
FR2581063B1 (fr) * 1985-04-30 1987-07-17 Chauvin Blache Lab Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique
JPS63152368A (ja) * 1986-06-03 1988-06-24 Sumitomo Pharmaceut Co Ltd 新規なアミノアゾ−ル誘導体およびその酸付加塩
JPH075579B2 (ja) * 1986-09-01 1995-01-25 吉富製薬株式会社 アミノチアゾ−ル化合物
JPH0753666B2 (ja) * 1987-09-14 1995-06-07 久光製薬株式会社 置換ジフェニルチアゾール誘導体からなる抗炎症剤
US5463524A (en) * 1989-08-10 1995-10-31 Commonwealth Scientific And Industrial Research Organisation Producing electrosuspensions
DE69132293D1 (de) * 1991-03-07 2000-08-10 Hisamitsu Pharmaceutical Co Diphenylthiazolderivate mit antiinflammatorischer aktivität
FR2692893B1 (fr) * 1992-06-24 1994-09-02 Sanofi Elf Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
EP1125932A3 (de) * 1994-07-27 2001-08-29 G.D. Searle & Co. Substituierte Thiazole zur Behandlung von Entzündungen
FR2754258B1 (fr) 1996-10-08 1998-12-31 Sanofi Sa Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
EP1261607B1 (de) * 2000-03-01 2008-11-12 Janssen Pharmaceutica N.V. 2,4-disubstituierte thiazolyl derivate
EP1423113A4 (de) * 2001-08-13 2007-04-18 Phenex Pharmaceuticals Ag Nr1h4-nuklearrezeptorbindende verbindungen
EP1432706A2 (de) * 2001-09-26 2004-06-30 Bayer Pharmaceuticals Corporation 3-pyridyl oder 4-isoquinolinylthiazole als c17,20 lyase-inhibitoren
BR0306811A (pt) 2002-01-11 2004-10-26 Sankyo Co Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero
EP1555264A1 (de) * 2004-01-15 2005-07-20 Sireen AG Fünfringheterocyclische Verbindungen als Inhibitoren der Familie der SRC Proteinkinasen.
KR20110136901A (ko) 2004-02-24 2011-12-21 상꾜 가부시키가이샤 아미노 알코올 화합물
UA92746C2 (en) 2005-05-09 2010-12-10 Акилайон Фармасьютикалз, Инк. Thiazole compounds and methods of use
CA2636077C (en) 2006-01-18 2012-01-03 Amgen Inc. Thiazole compounds as protein kinase b (pkb) inhibitors
WO2009011871A2 (en) 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of pkb
CA2692713A1 (en) 2007-07-17 2009-01-22 Amgen Inc. Heterocyclic modulators of pkb
WO2012170931A2 (en) 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2012170951A2 (en) * 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2013059677A1 (en) 2011-10-19 2013-04-25 Calcimedica, Inc. Compounds that modulate intracellular calcium
CN110590785B (zh) * 2019-09-23 2021-02-02 武汉大学 一种氨基噻唑类化合物及其制备方法与抗肠道病毒71型的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458526A (en) * 1966-09-26 1969-07-29 Upjohn Co Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles

Also Published As

Publication number Publication date
GB2022085B (en) 1983-01-12
FR2427333A1 (fr) 1979-12-28
DD144055A5 (de) 1980-09-24
AU511242B2 (en) 1980-08-07
IT1121238B (it) 1986-03-26
FI791754A (fi) 1979-11-26
FI68820C (fi) 1985-11-11
GB2022085A (en) 1979-12-12
HU180045B (en) 1983-01-28
SU843746A3 (ru) 1981-06-30
FI68820B (fi) 1985-07-31
DK177679A (da) 1979-12-03
DK150068C (da) 1987-06-29
DE2922523C2 (de) 1982-10-21
GR73142B (de) 1984-02-09
YU128879A (en) 1982-10-31
SE7904798L (sv) 1979-12-03
CA1117949A (en) 1982-02-09
PL216030A1 (de) 1980-03-10
NO150760B (no) 1984-09-03
SE438333B (sv) 1985-04-15
IL57450A (en) 1982-11-30
JPS54160369A (en) 1979-12-19
ES481220A1 (es) 1980-09-01
CH639653A5 (fr) 1983-11-30
NL178421C (nl) 1986-03-17
IL57450A0 (en) 1979-09-30
NO791831L (no) 1979-12-04
NL178421B (nl) 1985-10-16
SG56184G (en) 1985-03-08
MY8500318A (en) 1985-12-31
JPS5936988B2 (ja) 1984-09-06
CS216927B2 (en) 1982-12-31
ATA401679A (de) 1983-05-15
NO150760C (no) 1984-12-12
LU81349A1 (fr) 1979-12-07
IE791069L (en) 1979-12-02
NL7904337A (nl) 1979-12-04
FR2427333B1 (de) 1983-05-20
AR226285A1 (es) 1982-06-30
IT7923228A0 (it) 1979-06-01
PH17020A (en) 1984-05-11
HK66487A (en) 1987-09-25
BE876732A (fr) 1979-12-03
NZ190623A (en) 1984-07-06
DK150068B (da) 1986-12-01
PL117515B1 (en) 1981-08-31
PT69718A (en) 1979-07-01
EG14354A (en) 1984-06-30
AU4763479A (en) 1979-12-06
IE48426B1 (en) 1985-01-23
DE2922523A1 (de) 1979-12-06
YU40997B (en) 1986-10-31
ZA792729B (en) 1981-03-25
KE3459A (en) 1984-10-12

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee