AT375354B - Verfahren zur herstellung von neuen thiazolylmethylthioderivaten und von deren salzen - Google Patents

Verfahren zur herstellung von neuen thiazolylmethylthioderivaten und von deren salzen

Info

Publication number
AT375354B
AT375354B AT0793779A AT793779A AT375354B AT 375354 B AT375354 B AT 375354B AT 0793779 A AT0793779 A AT 0793779A AT 793779 A AT793779 A AT 793779A AT 375354 B AT375354 B AT 375354B
Authority
AT
Austria
Prior art keywords
thioderivatives
salts
producing new
thiazolyl methyl
new thiazolyl
Prior art date
Application number
AT0793779A
Other languages
English (en)
Other versions
ATA793779A (de
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ATA793779A publication Critical patent/ATA793779A/de
Application granted granted Critical
Publication of AT375354B publication Critical patent/AT375354B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT0793779A 1978-12-18 1979-12-17 Verfahren zur herstellung von neuen thiazolylmethylthioderivaten und von deren salzen AT375354B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/970,517 US4200578A (en) 1978-12-18 1978-12-18 Thiazole derivatives

Publications (2)

Publication Number Publication Date
ATA793779A ATA793779A (de) 1983-12-15
AT375354B true AT375354B (de) 1984-07-25

Family

ID=25517073

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0793779A AT375354B (de) 1978-12-18 1979-12-17 Verfahren zur herstellung von neuen thiazolylmethylthioderivaten und von deren salzen

Country Status (24)

Country Link
US (1) US4200578A (de)
JP (1) JPS5583768A (de)
KR (3) KR830001920B1 (de)
AT (1) AT375354B (de)
AU (1) AU533014B2 (de)
BE (1) BE880662A (de)
CA (1) CA1133909A (de)
CH (1) CH642956A5 (de)
DE (1) DE2950838A1 (de)
DK (1) DK533979A (de)
ES (2) ES487035A0 (de)
FI (1) FI793904A (de)
FR (1) FR2444674B1 (de)
GB (1) GB2038822B (de)
GR (1) GR73586B (de)
HU (1) HU182461B (de)
IE (1) IE49320B1 (de)
IL (1) IL58960A (de)
IT (1) IT1164076B (de)
LU (1) LU82000A1 (de)
NL (1) NL7909054A (de)
SE (1) SE444680B (de)
YU (3) YU292179A (de)
ZA (1) ZA796814B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31588E (en) * 1977-06-03 1984-05-22 Bristol-Myers Company Imidazolylmethylthioethyl alkynyl guanidines
GR71929B (de) * 1979-11-13 1983-08-19 Ici Ltd
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
US4760075A (en) * 1980-10-02 1988-07-26 Eli Lilly And Company N-thiazolylmethylthioalkyl-N-alkyl-amidines and related compounds
US4382090A (en) * 1980-10-02 1983-05-03 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds
US4904792A (en) * 1980-10-02 1990-02-27 Eli Lilly And Company N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds
NZ202797A (en) * 1981-12-28 1985-08-30 Lilly Co Eli Pyrimidine derivatives and pharmaceutical compositions
US4474794A (en) * 1982-03-19 1984-10-02 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds
US4458077A (en) * 1982-11-22 1984-07-03 American Home Products Corporation Heterocyclic anti-ulcer agents
JPS59104370A (ja) * 1982-12-03 1984-06-16 Kotobuki Seiyaku Kk チアゾ−ル誘導体及びその製造方法
IE56763B1 (en) * 1983-02-07 1991-12-04 Lilly Co Eli Improvements in or relating to the synthesis of nizatidine
ZA869438B (en) * 1985-12-18 1988-07-27 Lilly Co Eli Synthesis of nizatidine
JPH0247453U (de) * 1988-09-29 1990-03-30
EP4196793A1 (de) 2020-08-11 2023-06-21 Université de Strasbourg Auf lebermakrophagen abzielende h2-blocker zur prävention und behandlung von lebererkrankungen und krebs
CN111974333B (zh) * 2020-08-19 2023-06-09 宁夏亚东化工有限公司 噻唑生产线及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
BE804144A (en) 1972-09-05 1974-02-28 Smith Kline French Lab H-2-Receptor antihistamines esp gastric acid inhibitors - -N-cyano-N"-(heterocyclyl-alkyl-(thio oxa amino or methylene-alkyl)-guanidines
US4083988A (en) * 1972-09-05 1978-04-11 Smith Kline & French Laboratories Limited Pharmacologically active compounds
GB1421792A (en) 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
GB1553070A (en) 1975-05-21 1979-09-19 Smith Kline French Lab Thiourea guanidine and 1-nitro-2,2-diaminoethylene derivatives
ZA782129B (en) 1977-04-20 1979-03-28 Ici Ltd Hertocyclic derivatives
US4112234A (en) * 1977-08-22 1978-09-05 Bristol-Myers Company Imidazolylmethylthioethyl alkynyl guanidines

Also Published As

Publication number Publication date
IT7950977A0 (it) 1979-12-04
NL7909054A (nl) 1980-06-20
FR2444674B1 (fr) 1986-03-28
AU5371679A (en) 1980-06-26
SE7910392L (sv) 1980-06-19
BE880662A (fr) 1980-06-17
IL58960A (en) 1983-06-15
ZA796814B (en) 1980-11-26
GR73586B (de) 1984-03-26
ES8101569A1 (es) 1980-12-16
GB2038822A (en) 1980-07-30
ES493718A0 (es) 1981-09-01
IT1164076B (it) 1987-04-08
HU182461B (en) 1984-01-30
JPS639512B2 (de) 1988-02-29
FR2444674A1 (fr) 1980-07-18
LU82000A1 (de) 1980-07-21
KR840001074B1 (ko) 1984-07-31
IE49320B1 (en) 1985-09-18
KR840001075B1 (ko) 1984-07-31
KR840004685A (ko) 1984-10-22
KR840004686A (ko) 1984-10-22
KR830001920B1 (ko) 1983-09-23
FI793904A (fi) 1980-06-19
CA1133909A (en) 1982-10-19
YU259382A (en) 1983-02-28
SE444680B (sv) 1986-04-28
DE2950838A1 (de) 1980-07-03
US4200578A (en) 1980-04-29
IE792436L (en) 1980-06-18
ATA793779A (de) 1983-12-15
IL58960A0 (en) 1980-03-31
DK533979A (da) 1980-06-19
YU292179A (en) 1983-02-28
AU533014B2 (en) 1983-10-27
YU259482A (en) 1983-02-28
KR830001263A (ko) 1983-04-29
GB2038822B (en) 1983-01-19
CH642956A5 (fr) 1984-05-15
ES8106715A1 (es) 1981-09-01
JPS5583768A (en) 1980-06-24
ES487035A0 (es) 1980-12-16

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Legal Events

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ELJ Ceased due to non-payment of the annual fee