IT1164076B - Composti farmaceutici ad azione antiulcera e procedimento per la loro preparazione - Google Patents

Composti farmaceutici ad azione antiulcera e procedimento per la loro preparazione

Info

Publication number
IT1164076B
IT1164076B IT50977/79A IT5097779A IT1164076B IT 1164076 B IT1164076 B IT 1164076B IT 50977/79 A IT50977/79 A IT 50977/79A IT 5097779 A IT5097779 A IT 5097779A IT 1164076 B IT1164076 B IT 1164076B
Authority
IT
Italy
Prior art keywords
ulter
procedure
preparation
action
pharmaceutical compounds
Prior art date
Application number
IT50977/79A
Other languages
English (en)
Other versions
IT7950977A0 (it
Inventor
Aldo Antonio Algieri
Ronnie Ray Crenshaw
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT7950977A0 publication Critical patent/IT7950977A0/it
Application granted granted Critical
Publication of IT1164076B publication Critical patent/IT1164076B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IT50977/79A 1978-12-18 1979-12-04 Composti farmaceutici ad azione antiulcera e procedimento per la loro preparazione IT1164076B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/970,517 US4200578A (en) 1978-12-18 1978-12-18 Thiazole derivatives

Publications (2)

Publication Number Publication Date
IT7950977A0 IT7950977A0 (it) 1979-12-04
IT1164076B true IT1164076B (it) 1987-04-08

Family

ID=25517073

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50977/79A IT1164076B (it) 1978-12-18 1979-12-04 Composti farmaceutici ad azione antiulcera e procedimento per la loro preparazione

Country Status (24)

Country Link
US (1) US4200578A (it)
JP (1) JPS5583768A (it)
KR (3) KR830001920B1 (it)
AT (1) AT375354B (it)
AU (1) AU533014B2 (it)
BE (1) BE880662A (it)
CA (1) CA1133909A (it)
CH (1) CH642956A5 (it)
DE (1) DE2950838A1 (it)
DK (1) DK533979A (it)
ES (2) ES8101569A1 (it)
FI (1) FI793904A (it)
FR (1) FR2444674B1 (it)
GB (1) GB2038822B (it)
GR (1) GR73586B (it)
HU (1) HU182461B (it)
IE (1) IE49320B1 (it)
IL (1) IL58960A (it)
IT (1) IT1164076B (it)
LU (1) LU82000A1 (it)
NL (1) NL7909054A (it)
SE (1) SE444680B (it)
YU (3) YU292179A (it)
ZA (1) ZA796814B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31588E (en) * 1977-06-03 1984-05-22 Bristol-Myers Company Imidazolylmethylthioethyl alkynyl guanidines
GR71929B (it) * 1979-11-13 1983-08-19 Ici Ltd
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
US4904792A (en) * 1980-10-02 1990-02-27 Eli Lilly And Company N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds
US4382090A (en) * 1980-10-02 1983-05-03 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds
US4760075A (en) * 1980-10-02 1988-07-26 Eli Lilly And Company N-thiazolylmethylthioalkyl-N-alkyl-amidines and related compounds
CA1206151A (en) * 1981-12-28 1986-06-17 Richard P. Pioch Pyrimidone anti-ulcer agents
US4474794A (en) * 1982-03-19 1984-10-02 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds
US4458077A (en) * 1982-11-22 1984-07-03 American Home Products Corporation Heterocyclic anti-ulcer agents
JPS59104370A (ja) * 1982-12-03 1984-06-16 Kotobuki Seiyaku Kk チアゾ−ル誘導体及びその製造方法
DE3486032T2 (de) * 1983-02-07 1993-05-19 Lilly Co Eli Synthese von nizatidin.
IL80961A0 (en) * 1985-12-18 1987-03-31 Lilly Co Eli Synthesis of nizatidine
JPH0247453U (it) * 1988-09-29 1990-03-30
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer
CN111974333B (zh) * 2020-08-19 2023-06-09 宁夏亚东化工有限公司 噻唑生产线及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
BE804144A (en) 1972-09-05 1974-02-28 Smith Kline French Lab H-2-Receptor antihistamines esp gastric acid inhibitors - -N-cyano-N"-(heterocyclyl-alkyl-(thio oxa amino or methylene-alkyl)-guanidines
US4083988A (en) * 1972-09-05 1978-04-11 Smith Kline & French Laboratories Limited Pharmacologically active compounds
GB1421792A (en) 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
GB1553070A (en) 1975-05-21 1979-09-19 Smith Kline French Lab Thiourea guanidine and 1-nitro-2,2-diaminoethylene derivatives
NZ186965A (en) 1977-04-20 1980-02-21 Ici Ltd Guanidino derivatives and pharmaceutical compositions
US4112234A (en) * 1977-08-22 1978-09-05 Bristol-Myers Company Imidazolylmethylthioethyl alkynyl guanidines

Also Published As

Publication number Publication date
KR830001263A (ko) 1983-04-29
FI793904A (fi) 1980-06-19
KR840004685A (ko) 1984-10-22
KR840004686A (ko) 1984-10-22
ES493718A0 (es) 1981-09-01
IT7950977A0 (it) 1979-12-04
AU533014B2 (en) 1983-10-27
DE2950838A1 (de) 1980-07-03
GR73586B (it) 1984-03-26
CA1133909A (en) 1982-10-19
CH642956A5 (fr) 1984-05-15
KR840001075B1 (ko) 1984-07-31
SE444680B (sv) 1986-04-28
YU259482A (en) 1983-02-28
IL58960A0 (en) 1980-03-31
FR2444674A1 (fr) 1980-07-18
ATA793779A (de) 1983-12-15
ES487035A0 (es) 1980-12-16
DK533979A (da) 1980-06-19
YU292179A (en) 1983-02-28
FR2444674B1 (fr) 1986-03-28
IL58960A (en) 1983-06-15
ES8106715A1 (es) 1981-09-01
ES8101569A1 (es) 1980-12-16
ZA796814B (en) 1980-11-26
US4200578A (en) 1980-04-29
KR830001920B1 (ko) 1983-09-23
LU82000A1 (de) 1980-07-21
KR840001074B1 (ko) 1984-07-31
AT375354B (de) 1984-07-25
IE49320B1 (en) 1985-09-18
AU5371679A (en) 1980-06-26
JPS639512B2 (it) 1988-02-29
SE7910392L (sv) 1980-06-19
JPS5583768A (en) 1980-06-24
HU182461B (en) 1984-01-30
IE792436L (en) 1980-06-18
GB2038822A (en) 1980-07-30
BE880662A (fr) 1980-06-17
NL7909054A (nl) 1980-06-20
YU259382A (en) 1983-02-28
GB2038822B (en) 1983-01-19

Similar Documents

Publication Publication Date Title
IT1119284B (it) Derivati carbostirilici e procedimento per la loro preparazione
IT1119947B (it) Polisilossani tensioattivi e procedimento per la loro preparazione
IT1122011B (it) Complessi di platino-diammina e procedimento per la loro preparazione ed applicazione antitumorale
FI801876A (fi) Farmaceutiska preparat
IT1119272B (it) Pirimidoni e procedimento per la loro preparazione
IT1164076B (it) Composti farmaceutici ad azione antiulcera e procedimento per la loro preparazione
IT1123120B (it) Cefem derivati e procedimento per la loro preparazione
IT1164735B (it) Derivati adenosinici e procedimento per la loro preparazione
IT1143009B (it) Composti farmaceutici ad azione antisecretiva e procedimento di preparazione
IT7950267A0 (it) Amminoglucosidi loro preparazione eloro applicazione come medicamenti
IT1166756B (it) 1,3-diaril-2-imino-imidazolidine e 2-imino-esaidro-pirimidine sostituite e procedimento per la loro preparazione
IT1121483B (it) Derivati di benzotiepinici e procedimento per la loro preparazione
IT8048615A0 (it) Pirazinobenzodiazepine loro preparazione e loro impiego come medicamenti
IT1115153B (it) Analoghi di cefalosporina e procedimento per la loro preparazione
IT8148952A0 (it) Amminoglucosidi ammidinati procedimento per loro preparazione e loro impiego come medicamenti
IT1160450B (it) Composti nitrosureici e procedimento per la loro preparazione
IT1192795B (it) Analoghi di cefalosporina e procedimento per la loro preparazione
IT1171361B (it) Amminociclopentanon-ammidi e procedimento per la loro preparazione e formulazione farmaceutica
IT1113203B (it) Derivati steroideo-spiro-ossazolidinonici sostituiti e procedimento per la loro preparazione
IT1108793B (it) Antibiotici e procedimento per la loro preparazione
IT1165040B (it) Alcossialchilidenidrazinopiridazione e procedimento per la loro preparazione
IT7950162A0 (it) Amminoalchilguanidine sostituite eprocedimento per la loro preparazione
IT1165187B (it) Analoghi di cefalosporina e procedimento per la loro preparazione
IT1172127B (it) Tioacil - carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono ad azione mucclitica
IT1130215B (it) 3-ariltio-4-idrossipirrolidine 1-sostituite e procedimento per la loro preparazione