IL58960A - N-thiazolylmethylthioalkylguanidine(or aminoethenamine)derivatives and their preparation - Google Patents

N-thiazolylmethylthioalkylguanidine(or aminoethenamine)derivatives and their preparation

Info

Publication number
IL58960A
IL58960A IL58960A IL5896079A IL58960A IL 58960 A IL58960 A IL 58960A IL 58960 A IL58960 A IL 58960A IL 5896079 A IL5896079 A IL 5896079A IL 58960 A IL58960 A IL 58960A
Authority
IL
Israel
Prior art keywords
thiazolylmethylthioalkylguanidine
aminoethenamine
derivatives
preparation
Prior art date
Application number
IL58960A
Other languages
English (en)
Other versions
IL58960A0 (en
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IL58960A0 publication Critical patent/IL58960A0/xx
Publication of IL58960A publication Critical patent/IL58960A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IL58960A 1978-12-18 1979-12-14 N-thiazolylmethylthioalkylguanidine(or aminoethenamine)derivatives and their preparation IL58960A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/970,517 US4200578A (en) 1978-12-18 1978-12-18 Thiazole derivatives

Publications (2)

Publication Number Publication Date
IL58960A0 IL58960A0 (en) 1980-03-31
IL58960A true IL58960A (en) 1983-06-15

Family

ID=25517073

Family Applications (1)

Application Number Title Priority Date Filing Date
IL58960A IL58960A (en) 1978-12-18 1979-12-14 N-thiazolylmethylthioalkylguanidine(or aminoethenamine)derivatives and their preparation

Country Status (24)

Country Link
US (1) US4200578A (xx)
JP (1) JPS5583768A (xx)
KR (3) KR830001920B1 (xx)
AT (1) AT375354B (xx)
AU (1) AU533014B2 (xx)
BE (1) BE880662A (xx)
CA (1) CA1133909A (xx)
CH (1) CH642956A5 (xx)
DE (1) DE2950838A1 (xx)
DK (1) DK533979A (xx)
ES (2) ES487035A0 (xx)
FI (1) FI793904A (xx)
FR (1) FR2444674B1 (xx)
GB (1) GB2038822B (xx)
GR (1) GR73586B (xx)
HU (1) HU182461B (xx)
IE (1) IE49320B1 (xx)
IL (1) IL58960A (xx)
IT (1) IT1164076B (xx)
LU (1) LU82000A1 (xx)
NL (1) NL7909054A (xx)
SE (1) SE444680B (xx)
YU (3) YU292179A (xx)
ZA (1) ZA796814B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31588E (en) * 1977-06-03 1984-05-22 Bristol-Myers Company Imidazolylmethylthioethyl alkynyl guanidines
GR71929B (xx) * 1979-11-13 1983-08-19 Ici Ltd
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
US4760075A (en) * 1980-10-02 1988-07-26 Eli Lilly And Company N-thiazolylmethylthioalkyl-N-alkyl-amidines and related compounds
US4382090A (en) * 1980-10-02 1983-05-03 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds
US4904792A (en) * 1980-10-02 1990-02-27 Eli Lilly And Company N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds
NZ202797A (en) * 1981-12-28 1985-08-30 Lilly Co Eli Pyrimidine derivatives and pharmaceutical compositions
US4474794A (en) * 1982-03-19 1984-10-02 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds
US4458077A (en) * 1982-11-22 1984-07-03 American Home Products Corporation Heterocyclic anti-ulcer agents
JPS59104370A (ja) * 1982-12-03 1984-06-16 Kotobuki Seiyaku Kk チアゾ−ル誘導体及びその製造方法
IE56763B1 (en) * 1983-02-07 1991-12-04 Lilly Co Eli Improvements in or relating to the synthesis of nizatidine
ZA869438B (en) * 1985-12-18 1988-07-27 Lilly Co Eli Synthesis of nizatidine
JPH0247453U (xx) * 1988-09-29 1990-03-30
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer
CN111974333B (zh) * 2020-08-19 2023-06-09 宁夏亚东化工有限公司 噻唑生产线及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
BE804144A (en) 1972-09-05 1974-02-28 Smith Kline French Lab H-2-Receptor antihistamines esp gastric acid inhibitors - -N-cyano-N"-(heterocyclyl-alkyl-(thio oxa amino or methylene-alkyl)-guanidines
US4083988A (en) * 1972-09-05 1978-04-11 Smith Kline & French Laboratories Limited Pharmacologically active compounds
GB1421792A (en) 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
GB1553070A (en) 1975-05-21 1979-09-19 Smith Kline French Lab Thiourea guanidine and 1-nitro-2,2-diaminoethylene derivatives
ZA782129B (en) 1977-04-20 1979-03-28 Ici Ltd Hertocyclic derivatives
US4112234A (en) * 1977-08-22 1978-09-05 Bristol-Myers Company Imidazolylmethylthioethyl alkynyl guanidines

Also Published As

Publication number Publication date
IT7950977A0 (it) 1979-12-04
NL7909054A (nl) 1980-06-20
FR2444674B1 (fr) 1986-03-28
AU5371679A (en) 1980-06-26
SE7910392L (sv) 1980-06-19
BE880662A (fr) 1980-06-17
AT375354B (de) 1984-07-25
ZA796814B (en) 1980-11-26
GR73586B (xx) 1984-03-26
ES8101569A1 (es) 1980-12-16
GB2038822A (en) 1980-07-30
ES493718A0 (es) 1981-09-01
IT1164076B (it) 1987-04-08
HU182461B (en) 1984-01-30
JPS639512B2 (xx) 1988-02-29
FR2444674A1 (fr) 1980-07-18
LU82000A1 (de) 1980-07-21
KR840001074B1 (ko) 1984-07-31
IE49320B1 (en) 1985-09-18
KR840001075B1 (ko) 1984-07-31
KR840004685A (ko) 1984-10-22
KR840004686A (ko) 1984-10-22
KR830001920B1 (ko) 1983-09-23
FI793904A (fi) 1980-06-19
CA1133909A (en) 1982-10-19
YU259382A (en) 1983-02-28
SE444680B (sv) 1986-04-28
DE2950838A1 (de) 1980-07-03
US4200578A (en) 1980-04-29
IE792436L (en) 1980-06-18
ATA793779A (de) 1983-12-15
IL58960A0 (en) 1980-03-31
DK533979A (da) 1980-06-19
YU292179A (en) 1983-02-28
AU533014B2 (en) 1983-10-27
YU259482A (en) 1983-02-28
KR830001263A (ko) 1983-04-29
GB2038822B (en) 1983-01-19
CH642956A5 (fr) 1984-05-15
ES8106715A1 (es) 1981-09-01
JPS5583768A (en) 1980-06-24
ES487035A0 (es) 1980-12-16

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