PH24830A - Indolize compounds and compositions containing them - Google Patents

Indolize compounds and compositions containing them

Info

Publication number
PH24830A
PH24830A PH34827A PH34827A PH24830A PH 24830 A PH24830 A PH 24830A PH 34827 A PH34827 A PH 34827A PH 34827 A PH34827 A PH 34827A PH 24830 A PH24830 A PH 24830A
Authority
PH
Philippines
Prior art keywords
indolize
compounds
compositions containing
compositions
indolize compounds
Prior art date
Application number
PH34827A
Other languages
English (en)
Inventor
Jean Gubin
Pierre Chatelain
Marcel Descamps
Dino Nisato
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PH24830A publication Critical patent/PH24830A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH34827A 1986-02-14 1987-02-06 Indolize compounds and compositions containing them PH24830A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8602045A FR2594438B1 (fr) 1986-02-14 1986-02-14 Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant

Publications (1)

Publication Number Publication Date
PH24830A true PH24830A (en) 1990-10-30

Family

ID=9332147

Family Applications (1)

Application Number Title Priority Date Filing Date
PH34827A PH24830A (en) 1986-02-14 1987-02-06 Indolize compounds and compositions containing them

Country Status (33)

Country Link
US (5) US4957925A (de)
EP (1) EP0235111B1 (de)
JP (1) JP2547004B2 (de)
KR (1) KR870007931A (de)
AR (1) AR245127A1 (de)
AT (1) ATE62485T1 (de)
AU (1) AU587525B2 (de)
BE (1) BE1006666A4 (de)
CA (1) CA1310965C (de)
CZ (1) CZ281209B6 (de)
DD (1) DD264436A5 (de)
DE (1) DE3769174D1 (de)
DK (1) DK170403B1 (de)
ES (1) ES2040276T3 (de)
FI (1) FI84353C (de)
FR (1) FR2594438B1 (de)
GR (1) GR3001883T3 (de)
HU (1) HU196401B (de)
IE (1) IE59656B1 (de)
IL (1) IL81358A (de)
MA (1) MA20878A1 (de)
MY (1) MY101541A (de)
NO (1) NO165344C (de)
NZ (1) NZ219274A (de)
OA (1) OA08481A (de)
PH (1) PH24830A (de)
PL (2) PL152609B1 (de)
PT (1) PT84277B (de)
SK (1) SK279557B6 (de)
SU (2) SU1486064A3 (de)
TN (1) TNSN87021A1 (de)
YU (2) YU21287A (de)
ZA (1) ZA87471B (de)

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US5182291A (en) * 1986-02-14 1993-01-26 Sanofi Pyrozala-pyridyl aminoabkoxyphenol compounds
US5215988A (en) * 1986-02-14 1993-06-01 Sanofi Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2594438B1 (fr) * 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
FR2633622B1 (fr) * 1988-07-04 1991-05-17 Sanofi Sa Derives de sulfonyl indolizine, leur procede de preparation et leur utilisation comme intermediaires de synthese
CA2008985A1 (en) * 1989-02-06 1990-08-06 Jean Gubin Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2642755B1 (de) * 1989-02-07 1993-11-05 Sanofi
FR2642756B1 (fr) * 1989-02-07 1994-03-04 Sanofi Derives cycloaminoalkoxyphenyle, leur procede de preparation ainsi que les compositions pharmaceutiques ou veterinaires en contenant
JPH07103105B2 (ja) * 1989-05-12 1995-11-08 杏林製薬株式会社 インドール誘導体及びその製造方法
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
US5118707A (en) * 1990-10-31 1992-06-02 The Procter & Gamble Company Compositions for regulating skin wrinkles comprising a benzofuran derivative
DE69224850T2 (de) * 1991-08-09 1998-09-24 Nycomed Innovation Ab Verwendung von dauerhafte frei radikalen zur bilderzeugung mittels magnetischer resonanz
FR2692574B1 (fr) * 1992-06-23 1995-06-23 Sanofi Elf Derives hydroxy-4 benzenethio, leur preparation ainsi que leur utilisation pour la preparation de derives aminoalkoxybenzenesulfonyles.
FR2692578B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Derives d'indolizines, procede de preparation et utilisation pour la preparation de composes aminoalkoxybenzenesulfonyl-indolizines a activite pharmaceutique.
US5922773A (en) * 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment
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US6482854B1 (en) 1999-03-25 2002-11-19 Massachusetts Eye And Ear Infirmary Glaucoma treatment
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WO2002083863A2 (en) * 2001-04-17 2002-10-24 Sepracor, Inc. Thiazole and other heterocyclic ligands and use thereof
ES2366082T3 (es) * 2001-04-27 2011-10-17 EISAI R&D MANAGEMENT CO., LTD. Pirazolo 1,5-a piridinas y medicinas que las contienen.
FR2838123B1 (fr) 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
US20060052597A1 (en) * 2002-10-22 2006-03-09 Best Desmond J Aryloxyalkylamine derivatives as h3 receptor ligands
CN100528883C (zh) * 2003-01-31 2009-08-19 日本曹达株式会社 形成光变换性有机薄膜的新型化合物和有机薄膜形成体
NZ617083A (en) 2003-08-27 2015-04-24 Ophthotech Corp Combination therapy for the treatment of ocular neovascular disorders
US20060141049A1 (en) * 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
AU2005209201B2 (en) 2004-01-20 2010-06-03 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
US20050244461A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Controlled release drug delivery systems and methods for treatment of an eye
US20070059336A1 (en) * 2004-04-30 2007-03-15 Allergan, Inc. Anti-angiogenic sustained release intraocular implants and related methods
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US20050244465A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Drug delivery systems and methods for treatment of an eye
US7771742B2 (en) 2004-04-30 2010-08-10 Allergan, Inc. Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US8455656B2 (en) 2004-04-30 2013-06-04 Allergan, Inc. Kinase inhibitors
US20050244466A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Photodynamic therapy in conjunction with intraocular implants
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US20050244471A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Estradiol derivative and estratopone containing sustained release intraocular implants and related methods
US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US8512738B2 (en) 2004-04-30 2013-08-20 Allergan, Inc. Biodegradable intravitreal tyrosine kinase implants
WO2005110374A1 (en) * 2004-04-30 2005-11-24 Allergan, Inc. Intraocular drug delivery systems containing a therapeutic component, a cyclodextrin, and a polymeric component
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US20050244478A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Anti-excititoxic sustained release intraocular implants and related methods
US20050244463A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US20050244458A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular neuropathies
US8119154B2 (en) 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
US8425929B2 (en) * 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
US8591885B2 (en) * 2004-04-30 2013-11-26 Allergan, Inc. Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
US20050244462A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Devices and methods for treating a mammalian eye
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US8147865B2 (en) 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
WO2006017347A2 (en) * 2004-07-12 2006-02-16 Allergan, Inc. Opthalmic compositions and methods for treating ophthalmic conditions
WO2006043965A1 (en) * 2004-10-14 2006-04-27 Allergan, Inc. Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods
US20070293456A9 (en) * 2004-12-30 2007-12-20 Anthony Hayford Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds
CN101400349A (zh) * 2006-03-01 2009-04-01 罗斯坎普研究有限责任公司 抑制β-淀粉样蛋白产生的化合物
US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
EP2120557A4 (de) * 2006-12-08 2010-02-10 Roskamp Res Llc Polyhydrochinolinverbindungen und dihydropyridinverbindungen zur hemmung der beta-amyloid-produktion
US7911053B2 (en) * 2007-04-19 2011-03-22 Marvell World Trade Ltd. Semiconductor packaging with internal wiring bus
PT2266990E (pt) * 2008-04-15 2012-12-27 Eisai R&D Man Co Ltd Composto de 3-fenilpirazolo[5,1-b]tiazole
WO2011043387A1 (ja) * 2009-10-08 2011-04-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピラゾロオキサゾール化合物
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
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CA2901280A1 (en) 2013-02-15 2014-08-21 Allergan, Inc. Sustained drug delivery implant
CN108084186B (zh) * 2016-11-16 2021-06-25 江苏新元素医药科技有限公司 Urat1抑制剂及其应用
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FR2376145A1 (fr) * 1977-01-03 1978-07-28 Thea Therapeutiques Applic Sa Nouveaux derives de chromones a activite medicamenteuse et leur preparation
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IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them

Also Published As

Publication number Publication date
IL81358A (en) 1991-03-10
PL153650B1 (en) 1991-05-31
MA20878A1 (fr) 1987-10-01
YU46588A (en) 1989-08-31
EP0235111B1 (de) 1991-04-10
US4957925A (en) 1990-09-18
NZ219274A (en) 1989-04-26
DE3769174D1 (de) 1991-05-16
US5147878A (en) 1992-09-15
JP2547004B2 (ja) 1996-10-23
NO165344C (no) 1991-01-30
TNSN87021A1 (fr) 1990-01-01
GR3001883T3 (en) 1992-11-23
ATE62485T1 (de) 1991-04-15
YU21287A (en) 1988-08-31
FR2594438B1 (fr) 1990-01-26
CZ97787A3 (en) 1996-07-17
OA08481A (fr) 1988-07-29
ZA87471B (en) 1988-09-28
MY101541A (en) 1991-12-17
CA1310965C (en) 1992-12-01
JPS62192380A (ja) 1987-08-22
US5017579A (en) 1991-05-21
FI84353C (fi) 1991-11-25
SU1486064A3 (ru) 1989-06-07
DK74087D0 (da) 1987-02-13
ES2040276T3 (es) 1993-10-16
IE870345L (en) 1987-08-14
DK170403B1 (da) 1995-08-21
AU587525B2 (en) 1989-08-17
AR245127A1 (es) 1993-12-30
IE59656B1 (en) 1994-03-09
PL264078A1 (en) 1988-07-21
SU1528321A3 (ru) 1989-12-07
SK97787A3 (en) 1998-12-02
SK279557B6 (sk) 1998-12-02
HU196401B (en) 1988-11-28
IL81358A0 (en) 1987-08-31
AU6884687A (en) 1987-08-20
BE1006666A4 (fr) 1994-11-16
NO870579D0 (no) 1987-02-13
US4994474A (en) 1991-02-19
NO870579L (no) 1987-08-17
PT84277A (en) 1987-03-01
EP0235111A1 (de) 1987-09-02
KR870007931A (ko) 1987-09-23
US5039700A (en) 1991-08-13
DK74087A (da) 1987-08-15
FI84353B (fi) 1991-08-15
PT84277B (pt) 1989-09-14
FI870629A (fi) 1987-08-15
HUT43604A (en) 1987-11-30
FI870629A0 (fi) 1987-02-13
CZ281209B6 (cs) 1996-07-17
PL152609B1 (en) 1991-01-31
NO165344B (no) 1990-10-22
DD264436A5 (de) 1989-02-01
FR2594438A1 (fr) 1987-08-21

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