DK74087A - Indolizinderivater og fremgangsmaade til fremstilling deraf samt midler indeholdende derivaterne - Google Patents

Indolizinderivater og fremgangsmaade til fremstilling deraf samt midler indeholdende derivaterne

Info

Publication number
DK74087A
DK74087A DK074087A DK74087A DK74087A DK 74087 A DK74087 A DK 74087A DK 074087 A DK074087 A DK 074087A DK 74087 A DK74087 A DK 74087A DK 74087 A DK74087 A DK 74087A
Authority
DK
Denmark
Prior art keywords
derivatives
procedures
preparing
indolicine
mentals
Prior art date
Application number
DK074087A
Other languages
English (en)
Other versions
DK74087D0 (da
DK170403B1 (da
Inventor
Jean Gubin
Pierre Chatelain
Marcel Descamps
Dino Nisato
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK74087D0 publication Critical patent/DK74087D0/da
Publication of DK74087A publication Critical patent/DK74087A/da
Application granted granted Critical
Publication of DK170403B1 publication Critical patent/DK170403B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK074087A 1986-02-14 1987-02-13 Terapeutisk aktive indolizinderivater og fremgangsmåder til fremstilling deraf samt midler indeholdende derivaterne DK170403B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8602045 1986-02-14
FR8602045A FR2594438B1 (fr) 1986-02-14 1986-02-14 Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant

Publications (3)

Publication Number Publication Date
DK74087D0 DK74087D0 (da) 1987-02-13
DK74087A true DK74087A (da) 1987-08-15
DK170403B1 DK170403B1 (da) 1995-08-21

Family

ID=9332147

Family Applications (1)

Application Number Title Priority Date Filing Date
DK074087A DK170403B1 (da) 1986-02-14 1987-02-13 Terapeutisk aktive indolizinderivater og fremgangsmåder til fremstilling deraf samt midler indeholdende derivaterne

Country Status (33)

Country Link
US (5) US4957925A (da)
EP (1) EP0235111B1 (da)
JP (1) JP2547004B2 (da)
KR (1) KR870007931A (da)
AR (1) AR245127A1 (da)
AT (1) ATE62485T1 (da)
AU (1) AU587525B2 (da)
BE (1) BE1006666A4 (da)
CA (1) CA1310965C (da)
CZ (1) CZ97787A3 (da)
DD (1) DD264436A5 (da)
DE (1) DE3769174D1 (da)
DK (1) DK170403B1 (da)
ES (1) ES2040276T3 (da)
FI (1) FI84353C (da)
FR (1) FR2594438B1 (da)
GR (1) GR3001883T3 (da)
HU (1) HU196401B (da)
IE (1) IE59656B1 (da)
IL (1) IL81358A (da)
MA (1) MA20878A1 (da)
MY (1) MY101541A (da)
NO (1) NO165344C (da)
NZ (1) NZ219274A (da)
OA (1) OA08481A (da)
PH (1) PH24830A (da)
PL (2) PL152609B1 (da)
PT (1) PT84277B (da)
SK (1) SK97787A3 (da)
SU (2) SU1486064A3 (da)
TN (1) TNSN87021A1 (da)
YU (2) YU21287A (da)
ZA (1) ZA87471B (da)

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FR2594438B1 (fr) * 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
US5215988A (en) * 1986-02-14 1993-06-01 Sanofi Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
US5182291A (en) * 1986-02-14 1993-01-26 Sanofi Pyrozala-pyridyl aminoabkoxyphenol compounds
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
FR2633622B1 (fr) * 1988-07-04 1991-05-17 Sanofi Sa Derives de sulfonyl indolizine, leur procede de preparation et leur utilisation comme intermediaires de synthese
CA2008985A1 (en) * 1989-02-06 1990-08-06 Jean Gubin Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2642755B1 (da) * 1989-02-07 1993-11-05 Sanofi
FR2642756B1 (fr) * 1989-02-07 1994-03-04 Sanofi Derives cycloaminoalkoxyphenyle, leur procede de preparation ainsi que les compositions pharmaceutiques ou veterinaires en contenant
JPH07103105B2 (ja) * 1989-05-12 1995-11-08 杏林製薬株式会社 インドール誘導体及びその製造方法
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
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US6482854B1 (en) 1999-03-25 2002-11-19 Massachusetts Eye And Ear Infirmary Glaucoma treatment
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NZ546088A (en) 2003-08-27 2009-10-30 Ophthotech Corp Combination therapy for the treatment of ocular neovascular disorders using a PDGF antagonist and a VEGF antagonist
US20050101582A1 (en) * 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US20060141049A1 (en) * 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20050250737A1 (en) * 2003-11-12 2005-11-10 Allergan, Inc. Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods
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US7993634B2 (en) * 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US7771742B2 (en) 2004-04-30 2010-08-10 Allergan, Inc. Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US8455656B2 (en) 2004-04-30 2013-06-04 Allergan, Inc. Kinase inhibitors
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US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
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US20050244458A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular neuropathies
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US20050244472A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Intraocular drug delivery systems containing excipients with reduced toxicity and related methods
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
BRPI0510485A (pt) 2004-04-30 2007-11-13 Allergan Inc implantes inibidores de tirosina cinase intravìtreos biodegradáveis
US20070059336A1 (en) * 2004-04-30 2007-03-15 Allergan, Inc. Anti-angiogenic sustained release intraocular implants and related methods
US8425929B2 (en) * 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
US8147865B2 (en) * 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
US20050244478A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Anti-excititoxic sustained release intraocular implants and related methods
US20050244463A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US20050244465A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Drug delivery systems and methods for treatment of an eye
US8591885B2 (en) * 2004-04-30 2013-11-26 Allergan, Inc. Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
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US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
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Also Published As

Publication number Publication date
FI84353C (fi) 1991-11-25
AU6884687A (en) 1987-08-20
US4994474A (en) 1991-02-19
GR3001883T3 (en) 1992-11-23
MA20878A1 (fr) 1987-10-01
OA08481A (fr) 1988-07-29
EP0235111A1 (fr) 1987-09-02
HUT43604A (en) 1987-11-30
IL81358A0 (en) 1987-08-31
IE870345L (en) 1987-08-14
TNSN87021A1 (fr) 1990-01-01
DK74087D0 (da) 1987-02-13
SK279557B6 (sk) 1998-12-02
PL152609B1 (en) 1991-01-31
FI84353B (fi) 1991-08-15
SU1528321A3 (ru) 1989-12-07
NO870579D0 (no) 1987-02-13
YU21287A (en) 1988-08-31
FR2594438B1 (fr) 1990-01-26
NO870579L (no) 1987-08-17
SK97787A3 (en) 1998-12-02
PL264078A1 (en) 1988-07-21
KR870007931A (ko) 1987-09-23
FI870629A (fi) 1987-08-15
FR2594438A1 (fr) 1987-08-21
JPS62192380A (ja) 1987-08-22
JP2547004B2 (ja) 1996-10-23
US5017579A (en) 1991-05-21
YU46588A (en) 1989-08-31
HU196401B (en) 1988-11-28
IL81358A (en) 1991-03-10
ATE62485T1 (de) 1991-04-15
DE3769174D1 (de) 1991-05-16
ES2040276T3 (es) 1993-10-16
AR245127A1 (es) 1993-12-30
ZA87471B (en) 1988-09-28
US4957925A (en) 1990-09-18
PL153650B1 (en) 1991-05-31
US5039700A (en) 1991-08-13
PT84277A (en) 1987-03-01
AU587525B2 (en) 1989-08-17
IE59656B1 (en) 1994-03-09
CZ281209B6 (cs) 1996-07-17
FI870629A0 (fi) 1987-02-13
NO165344C (no) 1991-01-30
NZ219274A (en) 1989-04-26
SU1486064A3 (ru) 1989-06-07
BE1006666A4 (fr) 1994-11-16
PH24830A (en) 1990-10-30
US5147878A (en) 1992-09-15
MY101541A (en) 1991-12-17
NO165344B (no) 1990-10-22
DK170403B1 (da) 1995-08-21
EP0235111B1 (fr) 1991-04-10
DD264436A5 (de) 1989-02-01
PT84277B (pt) 1989-09-14
CA1310965C (en) 1992-12-01
CZ97787A3 (en) 1996-07-17

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