DK74087A - Indolizinderivater og fremgangsmaade til fremstilling deraf samt midler indeholdende derivaterne - Google Patents

Indolizinderivater og fremgangsmaade til fremstilling deraf samt midler indeholdende derivaterne

Info

Publication number
DK74087A
DK74087A DK074087A DK74087A DK74087A DK 74087 A DK74087 A DK 74087A DK 074087 A DK074087 A DK 074087A DK 74087 A DK74087 A DK 74087A DK 74087 A DK74087 A DK 74087A
Authority
DK
Denmark
Prior art keywords
derivatives
procedures
preparing
indolicine
mentals
Prior art date
Application number
DK074087A
Other languages
English (en)
Other versions
DK74087D0 (da
DK170403B1 (da
Inventor
Jean Gubin
Pierre Chatelain
Marcel Descamps
Dino Nisato
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK74087D0 publication Critical patent/DK74087D0/da
Publication of DK74087A publication Critical patent/DK74087A/da
Application granted granted Critical
Publication of DK170403B1 publication Critical patent/DK170403B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK074087A 1986-02-14 1987-02-13 Terapeutisk aktive indolizinderivater og fremgangsmåder til fremstilling deraf samt midler indeholdende derivaterne DK170403B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8602045A FR2594438B1 (fr) 1986-02-14 1986-02-14 Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
FR8602045 1986-02-14

Publications (3)

Publication Number Publication Date
DK74087D0 DK74087D0 (da) 1987-02-13
DK74087A true DK74087A (da) 1987-08-15
DK170403B1 DK170403B1 (da) 1995-08-21

Family

ID=9332147

Family Applications (1)

Application Number Title Priority Date Filing Date
DK074087A DK170403B1 (da) 1986-02-14 1987-02-13 Terapeutisk aktive indolizinderivater og fremgangsmåder til fremstilling deraf samt midler indeholdende derivaterne

Country Status (33)

Country Link
US (5) US4957925A (da)
EP (1) EP0235111B1 (da)
JP (1) JP2547004B2 (da)
KR (1) KR870007931A (da)
AR (1) AR245127A1 (da)
AT (1) ATE62485T1 (da)
AU (1) AU587525B2 (da)
BE (1) BE1006666A4 (da)
CA (1) CA1310965C (da)
CZ (1) CZ97787A3 (da)
DD (1) DD264436A5 (da)
DE (1) DE3769174D1 (da)
DK (1) DK170403B1 (da)
ES (1) ES2040276T3 (da)
FI (1) FI84353C (da)
FR (1) FR2594438B1 (da)
GR (1) GR3001883T3 (da)
HU (1) HU196401B (da)
IE (1) IE59656B1 (da)
IL (1) IL81358A (da)
MA (1) MA20878A1 (da)
MY (1) MY101541A (da)
NO (1) NO165344C (da)
NZ (1) NZ219274A (da)
OA (1) OA08481A (da)
PH (1) PH24830A (da)
PL (2) PL153650B1 (da)
PT (1) PT84277B (da)
SK (1) SK97787A3 (da)
SU (2) SU1486064A3 (da)
TN (1) TNSN87021A1 (da)
YU (2) YU21287A (da)
ZA (1) ZA87471B (da)

Families Citing this family (65)

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FR2594438B1 (fr) * 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
FR2633622B1 (fr) * 1988-07-04 1991-05-17 Sanofi Sa Derives de sulfonyl indolizine, leur procede de preparation et leur utilisation comme intermediaires de synthese
CA2008985A1 (en) * 1989-02-06 1990-08-06 Jean Gubin Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2642755B1 (da) * 1989-02-07 1993-11-05 Sanofi
FR2642756B1 (fr) * 1989-02-07 1994-03-04 Sanofi Derives cycloaminoalkoxyphenyle, leur procede de preparation ainsi que les compositions pharmaceutiques ou veterinaires en contenant
JPH07103105B2 (ja) * 1989-05-12 1995-11-08 杏林製薬株式会社 インドール誘導体及びその製造方法
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
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US5435991A (en) * 1991-08-09 1995-07-25 Nycomed Innovation Ab Use of persistent heterocyclic free-radicals in magnetic resonance imaging
FR2692574B1 (fr) * 1992-06-23 1995-06-23 Sanofi Elf Derives hydroxy-4 benzenethio, leur preparation ainsi que leur utilisation pour la preparation de derives aminoalkoxybenzenesulfonyles.
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US6482854B1 (en) 1999-03-25 2002-11-19 Massachusetts Eye And Ear Infirmary Glaucoma treatment
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FR2838123B1 (fr) 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
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US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US20050101582A1 (en) * 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20060141049A1 (en) * 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
AU2005209201B2 (en) 2004-01-20 2010-06-03 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US20050244471A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Estradiol derivative and estratopone containing sustained release intraocular implants and related methods
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US20050244478A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Anti-excititoxic sustained release intraocular implants and related methods
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US8455656B2 (en) 2004-04-30 2013-06-04 Allergan, Inc. Kinase inhibitors
US8147865B2 (en) 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
US20070059336A1 (en) * 2004-04-30 2007-03-15 Allergan, Inc. Anti-angiogenic sustained release intraocular implants and related methods
US8425929B2 (en) * 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US20050244472A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Intraocular drug delivery systems containing excipients with reduced toxicity and related methods
US20050244461A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Controlled release drug delivery systems and methods for treatment of an eye
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US20050244466A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Photodynamic therapy in conjunction with intraocular implants
US20050244462A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Devices and methods for treating a mammalian eye
US8591885B2 (en) * 2004-04-30 2013-11-26 Allergan, Inc. Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
US20050244465A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Drug delivery systems and methods for treatment of an eye
US7771742B2 (en) 2004-04-30 2010-08-10 Allergan, Inc. Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US20050244463A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US8119154B2 (en) * 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
US8512738B2 (en) 2004-04-30 2013-08-20 Allergan, Inc. Biodegradable intravitreal tyrosine kinase implants
US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
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WO2006073938A2 (en) * 2004-12-30 2006-07-13 East Carolina University Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds
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US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
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US7911053B2 (en) * 2007-04-19 2011-03-22 Marvell World Trade Ltd. Semiconductor packaging with internal wiring bus
SI2266990T1 (sl) * 2008-04-15 2013-01-31 Eisai R&D Management Co. Ltd. Spojina 3-fenilpirazolo(5,1-b)tiazola
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
JPWO2011043387A1 (ja) * 2009-10-08 2013-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピラゾロオキサゾール化合物
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JP6511401B2 (ja) 2013-02-15 2019-05-15 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 持続型薬物送達インプラント
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IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them

Also Published As

Publication number Publication date
IE870345L (en) 1987-08-14
SU1486064A3 (ru) 1989-06-07
FI870629A (fi) 1987-08-15
GR3001883T3 (en) 1992-11-23
SK279557B6 (sk) 1998-12-02
MA20878A1 (fr) 1987-10-01
TNSN87021A1 (fr) 1990-01-01
KR870007931A (ko) 1987-09-23
EP0235111A1 (fr) 1987-09-02
IL81358A0 (en) 1987-08-31
DK74087D0 (da) 1987-02-13
YU46588A (en) 1989-08-31
DE3769174D1 (de) 1991-05-16
CZ281209B6 (cs) 1996-07-17
JPS62192380A (ja) 1987-08-22
HUT43604A (en) 1987-11-30
US5039700A (en) 1991-08-13
NO165344B (no) 1990-10-22
CZ97787A3 (en) 1996-07-17
NO870579D0 (no) 1987-02-13
PT84277B (pt) 1989-09-14
US5147878A (en) 1992-09-15
CA1310965C (en) 1992-12-01
EP0235111B1 (fr) 1991-04-10
PL264078A1 (en) 1988-07-21
JP2547004B2 (ja) 1996-10-23
US4957925A (en) 1990-09-18
US4994474A (en) 1991-02-19
SU1528321A3 (ru) 1989-12-07
OA08481A (fr) 1988-07-29
US5017579A (en) 1991-05-21
FR2594438B1 (fr) 1990-01-26
AR245127A1 (es) 1993-12-30
PH24830A (en) 1990-10-30
DD264436A5 (de) 1989-02-01
FI84353C (fi) 1991-11-25
FI870629A0 (fi) 1987-02-13
FI84353B (fi) 1991-08-15
AU587525B2 (en) 1989-08-17
BE1006666A4 (fr) 1994-11-16
AU6884687A (en) 1987-08-20
PT84277A (en) 1987-03-01
PL152609B1 (en) 1991-01-31
HU196401B (en) 1988-11-28
ATE62485T1 (de) 1991-04-15
FR2594438A1 (fr) 1987-08-21
IL81358A (en) 1991-03-10
SK97787A3 (en) 1998-12-02
DK170403B1 (da) 1995-08-21
NO165344C (no) 1991-01-30
PL153650B1 (en) 1991-05-31
ZA87471B (en) 1988-09-28
YU21287A (en) 1988-08-31
NZ219274A (en) 1989-04-26
ES2040276T3 (es) 1993-10-16
NO870579L (no) 1987-08-17
MY101541A (en) 1991-12-17
IE59656B1 (en) 1994-03-09

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