YU46588A - Process for obtaining new derivtives of indolyzine - Google Patents

Process for obtaining new derivtives of indolyzine

Info

Publication number
YU46588A
YU46588A YU00465/88A YU46588A YU46588A YU 46588 A YU46588 A YU 46588A YU 00465/88 A YU00465/88 A YU 00465/88A YU 46588 A YU46588 A YU 46588A YU 46588 A YU46588 A YU 46588A
Authority
YU
Yugoslavia
Prior art keywords
indolyzine
derivtives
obtaining new
obtaining
new
Prior art date
Application number
YU00465/88A
Other languages
English (en)
Inventor
J Gubin
P Chatelain
M Descamps
D Nisato
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of YU46588A publication Critical patent/YU46588A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
YU00465/88A 1986-02-14 1988-03-08 Process for obtaining new derivtives of indolyzine YU46588A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8602045A FR2594438B1 (fr) 1986-02-14 1986-02-14 Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant

Publications (1)

Publication Number Publication Date
YU46588A true YU46588A (en) 1989-08-31

Family

ID=9332147

Family Applications (2)

Application Number Title Priority Date Filing Date
YU00212/87A YU21287A (en) 1986-02-14 1987-02-13 Process for obtaining new derivatives of indolizine
YU00465/88A YU46588A (en) 1986-02-14 1988-03-08 Process for obtaining new derivtives of indolyzine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
YU00212/87A YU21287A (en) 1986-02-14 1987-02-13 Process for obtaining new derivatives of indolizine

Country Status (33)

Country Link
US (5) US4957925A (xx)
EP (1) EP0235111B1 (xx)
JP (1) JP2547004B2 (xx)
KR (1) KR870007931A (xx)
AR (1) AR245127A1 (xx)
AT (1) ATE62485T1 (xx)
AU (1) AU587525B2 (xx)
BE (1) BE1006666A4 (xx)
CA (1) CA1310965C (xx)
CZ (1) CZ281209B6 (xx)
DD (1) DD264436A5 (xx)
DE (1) DE3769174D1 (xx)
DK (1) DK170403B1 (xx)
ES (1) ES2040276T3 (xx)
FI (1) FI84353C (xx)
FR (1) FR2594438B1 (xx)
GR (1) GR3001883T3 (xx)
HU (1) HU196401B (xx)
IE (1) IE59656B1 (xx)
IL (1) IL81358A (xx)
MA (1) MA20878A1 (xx)
MY (1) MY101541A (xx)
NO (1) NO165344C (xx)
NZ (1) NZ219274A (xx)
OA (1) OA08481A (xx)
PH (1) PH24830A (xx)
PL (2) PL153650B1 (xx)
PT (1) PT84277B (xx)
SK (1) SK97787A3 (xx)
SU (2) SU1486064A3 (xx)
TN (1) TNSN87021A1 (xx)
YU (2) YU21287A (xx)
ZA (1) ZA87471B (xx)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
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FR2594438B1 (fr) * 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
US5182291A (en) * 1986-02-14 1993-01-26 Sanofi Pyrozala-pyridyl aminoabkoxyphenol compounds
US5215988A (en) * 1986-02-14 1993-06-01 Sanofi Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
FR2633622B1 (fr) * 1988-07-04 1991-05-17 Sanofi Sa Derives de sulfonyl indolizine, leur procede de preparation et leur utilisation comme intermediaires de synthese
CA2008985A1 (en) * 1989-02-06 1990-08-06 Jean Gubin Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2642756B1 (fr) * 1989-02-07 1994-03-04 Sanofi Derives cycloaminoalkoxyphenyle, leur procede de preparation ainsi que les compositions pharmaceutiques ou veterinaires en contenant
FR2642755B1 (xx) * 1989-02-07 1993-11-05 Sanofi
JPH07103105B2 (ja) * 1989-05-12 1995-11-08 杏林製薬株式会社 インドール誘導体及びその製造方法
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
US5118707A (en) * 1990-10-31 1992-06-02 The Procter & Gamble Company Compositions for regulating skin wrinkles comprising a benzofuran derivative
DE69224850T2 (de) * 1991-08-09 1998-09-24 Nycomed Innovation Ab Verwendung von dauerhafte frei radikalen zur bilderzeugung mittels magnetischer resonanz
FR2692578B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Derives d'indolizines, procede de preparation et utilisation pour la preparation de composes aminoalkoxybenzenesulfonyl-indolizines a activite pharmaceutique.
FR2692574B1 (fr) * 1992-06-23 1995-06-23 Sanofi Elf Derives hydroxy-4 benzenethio, leur preparation ainsi que leur utilisation pour la preparation de derives aminoalkoxybenzenesulfonyles.
US5922773A (en) * 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment
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US6514971B1 (en) 1996-03-15 2003-02-04 Zeneca Limited Cinnoline derivatives and use as medicine
US6482854B1 (en) 1999-03-25 2002-11-19 Massachusetts Eye And Ear Infirmary Glaucoma treatment
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ES2366082T3 (es) * 2001-04-27 2011-10-17 EISAI R&D MANAGEMENT CO., LTD. Pirazolo 1,5-a piridinas y medicinas que las contienen.
FR2838123B1 (fr) * 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
AU2003274053A1 (en) * 2002-10-22 2004-05-13 Glaxo Group Limited Aryloxyalkylamine derivates as h3 receptor ligands
US7470803B2 (en) * 2003-01-31 2008-12-30 Nippon Soda Co., Ltd. Compounds for forming photoconvertible organic thin film and organic thin film formed body
CA2876822C (en) 2003-08-27 2015-11-17 David Shima Combination therapy for the treatment of ocular neovascular disorders
US20070224278A1 (en) * 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US20050250737A1 (en) * 2003-11-12 2005-11-10 Allergan, Inc. Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods
US20060141049A1 (en) * 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20050101582A1 (en) * 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
CN100548271C (zh) 2004-01-20 2009-10-14 阿勒根公司 用于眼部的局部治疗、并优选包括有曲安奈德及透明质酸的组合物
US20070059336A1 (en) * 2004-04-30 2007-03-15 Allergan, Inc. Anti-angiogenic sustained release intraocular implants and related methods
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US20050244462A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Devices and methods for treating a mammalian eye
US8512738B2 (en) 2004-04-30 2013-08-20 Allergan, Inc. Biodegradable intravitreal tyrosine kinase implants
US20050244458A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular neuropathies
US20050244466A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Photodynamic therapy in conjunction with intraocular implants
US20050244465A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Drug delivery systems and methods for treatment of an eye
US20050244463A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US20050244478A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Anti-excititoxic sustained release intraocular implants and related methods
US20050244471A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Estradiol derivative and estratopone containing sustained release intraocular implants and related methods
US8455656B2 (en) 2004-04-30 2013-06-04 Allergan, Inc. Kinase inhibitors
US8425929B2 (en) * 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
US8591885B2 (en) * 2004-04-30 2013-11-26 Allergan, Inc. Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
US20050244472A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Intraocular drug delivery systems containing excipients with reduced toxicity and related methods
US8147865B2 (en) * 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US20050244461A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Controlled release drug delivery systems and methods for treatment of an eye
US7771742B2 (en) 2004-04-30 2010-08-10 Allergan, Inc. Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US8119154B2 (en) 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
WO2006017347A2 (en) * 2004-07-12 2006-02-16 Allergan, Inc. Opthalmic compositions and methods for treating ophthalmic conditions
WO2006073938A2 (en) * 2004-12-30 2006-07-13 East Carolina University Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds
AU2007223556A1 (en) * 2006-03-01 2007-09-13 Roskamp Research Llc Compounds for inhibiting beta-amyloid production
US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
EP2120557A4 (en) * 2006-12-08 2010-02-10 Roskamp Res Llc POLYHYDROQUINOLINE COMPOUNDS AND DIHYDROPYRIDINE COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION
US7911053B2 (en) * 2007-04-19 2011-03-22 Marvell World Trade Ltd. Semiconductor packaging with internal wiring bus
WO2009128383A1 (ja) * 2008-04-15 2009-10-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 ３－フェニルピラゾロ［５，１－ｂ］チアゾール化合物
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
WO2011043387A1 (ja) * 2009-10-08 2011-04-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピラゾロオキサゾール化合物
WO2011057129A2 (en) 2009-11-09 2011-05-12 Allergan, Inc. Compositions and methods for stimulating hair growth
JP6511401B2 (ja) 2013-02-15 2019-05-15 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 持続型薬物送達インプラント
CN108084186B (zh) * 2016-11-16 2021-06-25 江苏新元素医药科技有限公司 Urat1抑制剂及其应用
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US3485835A (en) * 1968-04-10 1969-12-23 Haessle Ab 2-benzoyl-3-tertiaryamino alkoxy benzofuran derivatives
IL32186A (en) * 1968-05-24 1974-10-22 Fisons Ltd 5-benzofuranyl compounds,their preparation,and physiologically active compositions containing them
US3860609A (en) * 1969-05-27 1975-01-14 Novo Terapeutisk Labor As 3-aminoalkyloxyindoles
US3859305A (en) * 1970-03-10 1975-01-07 Degussa Indole aminoketones
SE379196B (xx) * 1971-06-24 1975-09-29 Sandoz Ag
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FI61030C (fi) * 1976-02-19 1982-05-10 Sanofi Sa Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat
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FR2376145A1 (fr) * 1977-01-03 1978-07-28 Thea Therapeutiques Applic Sa Nouveaux derives de chromones a activite medicamenteuse et leur preparation
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FR2584723B1 (fr) * 1985-07-09 1988-02-12 Adir Nouveaux derives du dihydro-2,3 benzofuranne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
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FR2594438B1 (fr) * 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
US4873259A (en) * 1987-06-10 1989-10-10 Abbott Laboratories Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them

Also Published As

Publication number Publication date
FI84353C (fi) 1991-11-25
NO165344C (no) 1991-01-30
CZ97787A3 (en) 1996-07-17
KR870007931A (ko) 1987-09-23
JP2547004B2 (ja) 1996-10-23
GR3001883T3 (en) 1992-11-23
FI84353B (fi) 1991-08-15
IE59656B1 (en) 1994-03-09
OA08481A (fr) 1988-07-29
HU196401B (en) 1988-11-28
SK279557B6 (sk) 1998-12-02
AR245127A1 (es) 1993-12-30
NO165344B (no) 1990-10-22
TNSN87021A1 (fr) 1990-01-01
AU587525B2 (en) 1989-08-17
CA1310965C (en) 1992-12-01
ZA87471B (en) 1988-09-28
JPS62192380A (ja) 1987-08-22
US5039700A (en) 1991-08-13
ATE62485T1 (de) 1991-04-15
SU1528321A3 (ru) 1989-12-07
NZ219274A (en) 1989-04-26
DE3769174D1 (de) 1991-05-16
US4957925A (en) 1990-09-18
IL81358A (en) 1991-03-10
FR2594438B1 (fr) 1990-01-26
BE1006666A4 (fr) 1994-11-16
DK74087A (da) 1987-08-15
FR2594438A1 (fr) 1987-08-21
NO870579D0 (no) 1987-02-13
AU6884687A (en) 1987-08-20
SU1486064A3 (ru) 1989-06-07
MA20878A1 (fr) 1987-10-01
PL152609B1 (en) 1991-01-31
SK97787A3 (en) 1998-12-02
IE870345L (en) 1987-08-14
FI870629A (fi) 1987-08-15
EP0235111B1 (fr) 1991-04-10
YU21287A (en) 1988-08-31
PH24830A (en) 1990-10-30
HUT43604A (en) 1987-11-30
NO870579L (no) 1987-08-17
US5017579A (en) 1991-05-21
MY101541A (en) 1991-12-17
EP0235111A1 (fr) 1987-09-02
FI870629A0 (fi) 1987-02-13
US5147878A (en) 1992-09-15
PT84277B (pt) 1989-09-14
ES2040276T3 (es) 1993-10-16
IL81358A0 (en) 1987-08-31
PL264078A1 (en) 1988-07-21
DK170403B1 (da) 1995-08-21
DD264436A5 (de) 1989-02-01
PL153650B1 (en) 1991-05-31
CZ281209B6 (cs) 1996-07-17
US4994474A (en) 1991-02-19
PT84277A (en) 1987-03-01
DK74087D0 (da) 1987-02-13

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