PE61899A1 - Composicion farmaceutica para reducir la hipertension ocular que comprende una prostaglandina y un agente de ajuste de tonicidad no ionico - Google Patents
Composicion farmaceutica para reducir la hipertension ocular que comprende una prostaglandina y un agente de ajuste de tonicidad no ionicoInfo
- Publication number
- PE61899A1 PE61899A1 PE1998000177A PE00017798A PE61899A1 PE 61899 A1 PE61899 A1 PE 61899A1 PE 1998000177 A PE1998000177 A PE 1998000177A PE 00017798 A PE00017798 A PE 00017798A PE 61899 A1 PE61899 A1 PE 61899A1
- Authority
- PE
- Peru
- Prior art keywords
- composition
- mixtures
- conservative
- ionic
- prostaglandine
- Prior art date
Links
- 206010020772 Hypertension Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000002978 peroxides Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- -1 FATTY ACID ESTERS Chemical class 0.000 abstract 1
- SBKRTALNRRAOJP-BWSIXKJUSA-N N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methylheptanamide (6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide sulfuric acid Polymers OS(O)(=O)=O.CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCN)NC1=O)[C@@H](C)O.CC[C@H](C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCN)NC1=O)[C@@H](C)O SBKRTALNRRAOJP-BWSIXKJUSA-N 0.000 abstract 1
- 229920001214 Polysorbate 60 Polymers 0.000 abstract 1
- 150000001642 boronic acid derivatives Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 1
- 229920000136 polysorbate Polymers 0.000 abstract 1
- 229950008882 polysorbate Drugs 0.000 abstract 1
- 229920000053 polysorbate 80 Polymers 0.000 abstract 1
- 229940068968 polysorbate 80 Drugs 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81922197A | 1997-03-17 | 1997-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE61899A1 true PE61899A1 (es) | 1999-06-30 |
Family
ID=38729083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000177A PE61899A1 (es) | 1997-03-17 | 1998-03-13 | Composicion farmaceutica para reducir la hipertension ocular que comprende una prostaglandina y un agente de ajuste de tonicidad no ionico |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP0969846B2 (https=) |
| JP (2) | JP4920124B2 (https=) |
| KR (1) | KR100555818B1 (https=) |
| CN (1) | CN1236775C (https=) |
| AR (2) | AR002194A1 (https=) |
| AT (1) | ATE257385T1 (https=) |
| AU (1) | AU738781B2 (https=) |
| BR (2) | BR9808016A (https=) |
| CA (1) | CA2280089C (https=) |
| CL (1) | CL2009001870A1 (https=) |
| CO (1) | CO4940427A1 (https=) |
| CY (1) | CY2526B1 (https=) |
| CZ (1) | CZ299833B6 (https=) |
| DE (1) | DE69820997T3 (https=) |
| DK (1) | DK0969846T4 (https=) |
| EE (1) | EE04091B1 (https=) |
| ES (1) | ES2214706T5 (https=) |
| HU (1) | HU228896B1 (https=) |
| ID (1) | ID22389A (https=) |
| IL (1) | IL131041A0 (https=) |
| MY (1) | MY122237A (https=) |
| NO (1) | NO327713B1 (https=) |
| NZ (1) | NZ337322A (https=) |
| PE (1) | PE61899A1 (https=) |
| PL (1) | PL197509B1 (https=) |
| PT (1) | PT969846E (https=) |
| RU (1) | RU2197970C2 (https=) |
| SI (1) | SI0969846T2 (https=) |
| TW (1) | TW527187B (https=) |
| UA (1) | UA63938C2 (https=) |
| WO (1) | WO1998041208A1 (https=) |
| ZA (1) | ZA982188B (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6011062A (en) * | 1994-12-22 | 2000-01-04 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
| AR002194A1 (es) * | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
| US6187818B1 (en) | 1998-06-17 | 2001-02-13 | Pharmacia & Upjohn Company | Prostaglandins formulation and process |
| JP4880808B2 (ja) * | 1999-11-15 | 2012-02-22 | 久光製薬株式会社 | 人工涙液型点眼剤組成物 |
| JP4000505B2 (ja) * | 1999-12-01 | 2007-10-31 | 第一三共株式会社 | 緑内障を治療するための併用剤 |
| CA2422031C (en) * | 2000-09-13 | 2011-11-15 | Santen Pharmaceutical Co., Ltd. | Ophthalmic solutions comprising difluoroprostaglandin f2 alpha |
| AU2002218527A1 (en) * | 2000-12-05 | 2002-06-18 | Sankyo Company Limited | Ocular tension-lowering compositions for topical administration |
| US20020198209A1 (en) * | 2001-05-03 | 2002-12-26 | Allergan Sales Inc. | Compositions having enhanced pharmacokinetic characteristics |
| US7074827B2 (en) | 2002-10-24 | 2006-07-11 | Sucampo Ag (Usa) Inc. | Method for treating ocular hypertension and glaucoma |
| RU2266572C1 (ru) * | 2004-03-17 | 2005-12-20 | Российский государственный медицинский университет | Способ моделирования злокачественной артериальной гипертонии |
| WO2005089755A1 (en) * | 2004-03-18 | 2005-09-29 | R-Tech Ueno, Ltd. | Aqueous composition comprising thiazole derivative |
| US8569367B2 (en) | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| GB0501192D0 (en) * | 2005-01-20 | 2005-03-02 | Resolution Chemicals Ltd | Stable prostaglandin-containing compositions |
| US7851504B2 (en) * | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
| DE202005005094U1 (de) * | 2005-03-31 | 2005-07-28 | Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh | Ophthalmische Zusammensetzung |
| EP1916002B1 (en) * | 2005-08-02 | 2014-03-05 | Santen Pharmaceutical Co., Ltd. | Method for prevention of degradation of thermally unstable substance |
| JP5252787B2 (ja) * | 2005-08-02 | 2013-07-31 | 参天製薬株式会社 | 熱的に不安定な薬物の分解抑制方法 |
| JP2007099647A (ja) * | 2005-09-30 | 2007-04-19 | Kobayashi Pharmaceut Co Ltd | 粘膜適用組成物 |
| US8168206B1 (en) | 2005-10-06 | 2012-05-01 | Allergan, Inc. | Animal protein-free pharmaceutical compositions |
| CN101400354B (zh) * | 2006-03-13 | 2014-10-22 | 株式会社·R-技术上野 | 水性组合物 |
| KR101454674B1 (ko) * | 2006-03-17 | 2014-10-27 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | 산화에 불안정한 성분을 포함하는 안정화된 안과용 조성물 |
| RU2465898C2 (ru) * | 2006-10-31 | 2012-11-10 | Алькон Рисерч, Лтд. | Модуляторы связывания pai-1 для лечения глазных болезней |
| WO2008096804A1 (ja) * | 2007-02-07 | 2008-08-14 | Teika Pharmaceutical Co., Ltd. | ラタノプロスト含有点眼剤 |
| JP2009073788A (ja) * | 2007-09-21 | 2009-04-09 | Teika Seiyaku Kk | イソプロピルウノプロストン含有眼用組成物 |
| NZ584275A (en) * | 2007-10-08 | 2012-06-29 | Fovea Pharmaceuticals | Aqueous cyclosporine ophthalmic formulations |
| ES2638771T3 (es) * | 2008-03-17 | 2017-10-24 | Novartis Ag | Composiciones farmacéuticas acuosas que contienen complejos de borato-poliol |
| TWI544927B (zh) * | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| RU2402316C2 (ru) * | 2009-01-11 | 2010-10-27 | Пшеничников Виталий Георгиевич | Фармацевтическая антиглаукомная композиция |
| US8952051B2 (en) | 2009-11-05 | 2015-02-10 | Allergan, Inc. | Ophthalmic formulations containing substituted gamma lactams and methods for use thereof |
| CN103596572A (zh) * | 2011-04-12 | 2014-02-19 | 株式会社·R-技术上野 | 水性眼用组合物 |
| US20130029919A1 (en) * | 2011-07-26 | 2013-01-31 | Allergan, Inc. | Two part formulation system for opthalmic delivery |
| EP2567689A1 (en) | 2011-09-12 | 2013-03-13 | Visiotact Pharma | Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid |
| US8957048B2 (en) | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
| CA2858574C (en) | 2011-12-07 | 2017-05-30 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| NZ732058A (en) | 2014-11-25 | 2023-06-30 | Allergan Inc | Stabilized omega-3 ophthalmic compositions |
| AU2019343188A1 (en) * | 2018-09-21 | 2021-05-20 | Aufbau Medical Innovations Limited | Compositions and methods for glaucoma |
| AU2020272127B2 (en) | 2019-04-12 | 2022-12-08 | Ecolab Usa Inc. | Antimicrobial multi-purpose cleaner and methods of making and using the same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69100171T2 (de) * | 1990-05-22 | 1993-10-28 | Ueno Seiyaku Oyo Kenkyujo Kk | Synergistische Kombination zur ophthalmischen Verwendung. |
| WO1992013836A1 (en) * | 1991-02-07 | 1992-08-20 | Allergan, Inc. | 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f derivatives |
| US5767154A (en) * | 1991-02-07 | 1998-06-16 | Allergan | 5-trans-prostaglandins of the F series and their use as ocular hypotensives |
| EP0708646A1 (en) * | 1994-05-06 | 1996-05-01 | Alcon Laboratories, Inc. | Use of vitamin e tocopheryl derivatives in ophthalmic compositions |
| US5631287A (en) † | 1994-12-22 | 1997-05-20 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
| US5558876A (en) * | 1995-03-29 | 1996-09-24 | Alcon Laboratories, Inc. | Topical ophthalmic acidic drug formulations |
| AR002194A1 (es) * | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
-
1996
- 1996-06-03 AR ARP960102868A patent/AR002194A1/es unknown
-
1998
- 1998-03-09 MY MYPI98001017A patent/MY122237A/en unknown
- 1998-03-13 WO PCT/EP1998/001483 patent/WO1998041208A1/en not_active Ceased
- 1998-03-13 KR KR1019997008431A patent/KR100555818B1/ko not_active Expired - Fee Related
- 1998-03-13 HU HU0002194A patent/HU228896B1/hu not_active IP Right Cessation
- 1998-03-13 CA CA002280089A patent/CA2280089C/en not_active Expired - Fee Related
- 1998-03-13 EE EEP199900410A patent/EE04091B1/xx not_active IP Right Cessation
- 1998-03-13 CZ CZ0325799A patent/CZ299833B6/cs not_active IP Right Cessation
- 1998-03-13 BR BR9808016-4A patent/BR9808016A/pt not_active Application Discontinuation
- 1998-03-13 AU AU70353/98A patent/AU738781B2/en not_active Ceased
- 1998-03-13 CO CO98014184A patent/CO4940427A1/es unknown
- 1998-03-13 EP EP98916948A patent/EP0969846B2/en not_active Expired - Lifetime
- 1998-03-13 PT PT98916948T patent/PT969846E/pt unknown
- 1998-03-13 DE DE69820997T patent/DE69820997T3/de not_active Expired - Lifetime
- 1998-03-13 CN CNB988030195A patent/CN1236775C/zh not_active Expired - Fee Related
- 1998-03-13 PE PE1998000177A patent/PE61899A1/es not_active Application Discontinuation
- 1998-03-13 RU RU99121641/14A patent/RU2197970C2/ru not_active IP Right Cessation
- 1998-03-13 AR ARP980101150A patent/AR011192A1/es not_active Application Discontinuation
- 1998-03-13 BR BRPI9816218A patent/BRPI9816218B1/pt not_active IP Right Cessation
- 1998-03-13 IL IL13104198A patent/IL131041A0/xx not_active IP Right Cessation
- 1998-03-13 DK DK98916948.7T patent/DK0969846T4/da active
- 1998-03-13 ID IDW991029A patent/ID22389A/id unknown
- 1998-03-13 AT AT98916948T patent/ATE257385T1/de active
- 1998-03-13 PL PL335168A patent/PL197509B1/pl unknown
- 1998-03-13 UA UA99095110A patent/UA63938C2/uk unknown
- 1998-03-13 NZ NZ337322A patent/NZ337322A/en not_active IP Right Cessation
- 1998-03-13 JP JP54012698A patent/JP4920124B2/ja not_active Expired - Lifetime
- 1998-03-13 ES ES98916948T patent/ES2214706T5/es not_active Expired - Lifetime
- 1998-03-13 SI SI9830616T patent/SI0969846T2/sl unknown
- 1998-03-16 ZA ZA982188A patent/ZA982188B/xx unknown
- 1998-03-16 TW TW087103809A patent/TW527187B/zh not_active IP Right Cessation
-
1999
- 1999-09-16 NO NO19994481A patent/NO327713B1/no not_active IP Right Cessation
-
2005
- 2005-05-26 CY CY0500033A patent/CY2526B1/xx unknown
-
2009
- 2009-09-16 CL CL2009001870A patent/CL2009001870A1/es unknown
- 2009-10-09 JP JP2009235214A patent/JP2010043110A/ja active Pending
Also Published As
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| FR2790953B1 (fr) | Composition a phase aqueuse continue renfermant de l'acide l-2-oxothiazolidine 4-carboxylique | |
| ES2163528T3 (es) | Una solucion acuosa para infusion, estable al almacenamiento, que contiene un inhibidor de trombina. | |
| SE8705064D0 (sv) | Emulsion for parenteral administrering |
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