KR100555818B1 - 안내압 항진을 감소시키기 위한 조성물 및 방법 - Google Patents

안내압 항진을 감소시키기 위한 조성물 및 방법 Download PDF

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Publication number
KR100555818B1
KR100555818B1 KR1019997008431A KR19997008431A KR100555818B1 KR 100555818 B1 KR100555818 B1 KR 100555818B1 KR 1019997008431 A KR1019997008431 A KR 1019997008431A KR 19997008431 A KR19997008431 A KR 19997008431A KR 100555818 B1 KR100555818 B1 KR 100555818B1
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KR
South Korea
Prior art keywords
composition
weight
preservative
prostaglandin
nonionic
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1019997008431A
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English (en)
Korean (ko)
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KR20000076330A (ko
Inventor
리드케네쓰워렌
옌샤우-퐁
소우메리
피콕레지나플린
Original Assignee
노파르티스 아게
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38729083&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100555818(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20000076330A publication Critical patent/KR20000076330A/ko
Application granted granted Critical
Publication of KR100555818B1 publication Critical patent/KR100555818B1/ko
Assigned to 가부시키가이샤 아루떼꾸 우에노 reassignment 가부시키가이샤 아루떼꾸 우에노 권리의 전부이전등록 Assignors: 노파르티스 아게
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019997008431A 1997-03-17 1998-03-13 안내압 항진을 감소시키기 위한 조성물 및 방법 Expired - Fee Related KR100555818B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81922197A 1997-03-17 1997-03-17
US08/819,221 1997-03-17
US8/819,221 1997-03-17
PCT/EP1998/001483 WO1998041208A1 (en) 1997-03-17 1998-03-13 Compositions and methods for reducing ocular hypertension

Publications (2)

Publication Number Publication Date
KR20000076330A KR20000076330A (ko) 2000-12-26
KR100555818B1 true KR100555818B1 (ko) 2006-03-03

Family

ID=38729083

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019997008431A Expired - Fee Related KR100555818B1 (ko) 1997-03-17 1998-03-13 안내압 항진을 감소시키기 위한 조성물 및 방법

Country Status (32)

Country Link
EP (1) EP0969846B2 (https=)
JP (2) JP4920124B2 (https=)
KR (1) KR100555818B1 (https=)
CN (1) CN1236775C (https=)
AR (2) AR002194A1 (https=)
AT (1) ATE257385T1 (https=)
AU (1) AU738781B2 (https=)
BR (2) BR9808016A (https=)
CA (1) CA2280089C (https=)
CL (1) CL2009001870A1 (https=)
CO (1) CO4940427A1 (https=)
CY (1) CY2526B1 (https=)
CZ (1) CZ299833B6 (https=)
DE (1) DE69820997T3 (https=)
DK (1) DK0969846T4 (https=)
EE (1) EE04091B1 (https=)
ES (1) ES2214706T5 (https=)
HU (1) HU228896B1 (https=)
ID (1) ID22389A (https=)
IL (1) IL131041A0 (https=)
MY (1) MY122237A (https=)
NO (1) NO327713B1 (https=)
NZ (1) NZ337322A (https=)
PE (1) PE61899A1 (https=)
PL (1) PL197509B1 (https=)
PT (1) PT969846E (https=)
RU (1) RU2197970C2 (https=)
SI (1) SI0969846T2 (https=)
TW (1) TW527187B (https=)
UA (1) UA63938C2 (https=)
WO (1) WO1998041208A1 (https=)
ZA (1) ZA982188B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101382922B1 (ko) * 2006-03-13 2014-04-08 가부시키가이샤 아루떼꾸 우에노 수성 조성물

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011062A (en) * 1994-12-22 2000-01-04 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.
US6187818B1 (en) 1998-06-17 2001-02-13 Pharmacia & Upjohn Company Prostaglandins formulation and process
JP4880808B2 (ja) * 1999-11-15 2012-02-22 久光製薬株式会社 人工涙液型点眼剤組成物
JP4000505B2 (ja) * 1999-12-01 2007-10-31 第一三共株式会社 緑内障を治療するための併用剤
CA2422031C (en) * 2000-09-13 2011-11-15 Santen Pharmaceutical Co., Ltd. Ophthalmic solutions comprising difluoroprostaglandin f2 alpha
AU2002218527A1 (en) * 2000-12-05 2002-06-18 Sankyo Company Limited Ocular tension-lowering compositions for topical administration
US20020198209A1 (en) * 2001-05-03 2002-12-26 Allergan Sales Inc. Compositions having enhanced pharmacokinetic characteristics
US7074827B2 (en) 2002-10-24 2006-07-11 Sucampo Ag (Usa) Inc. Method for treating ocular hypertension and glaucoma
RU2266572C1 (ru) * 2004-03-17 2005-12-20 Российский государственный медицинский университет Способ моделирования злокачественной артериальной гипертонии
WO2005089755A1 (en) * 2004-03-18 2005-09-29 R-Tech Ueno, Ltd. Aqueous composition comprising thiazole derivative
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
GB0501192D0 (en) * 2005-01-20 2005-03-02 Resolution Chemicals Ltd Stable prostaglandin-containing compositions
US7851504B2 (en) * 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
DE202005005094U1 (de) * 2005-03-31 2005-07-28 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Ophthalmische Zusammensetzung
EP1916002B1 (en) * 2005-08-02 2014-03-05 Santen Pharmaceutical Co., Ltd. Method for prevention of degradation of thermally unstable substance
JP5252787B2 (ja) * 2005-08-02 2013-07-31 参天製薬株式会社 熱的に不安定な薬物の分解抑制方法
JP2007099647A (ja) * 2005-09-30 2007-04-19 Kobayashi Pharmaceut Co Ltd 粘膜適用組成物
US8168206B1 (en) 2005-10-06 2012-05-01 Allergan, Inc. Animal protein-free pharmaceutical compositions
KR101454674B1 (ko) * 2006-03-17 2014-10-27 존슨 앤드 존슨 비젼 케어, 인코포레이티드 산화에 불안정한 성분을 포함하는 안정화된 안과용 조성물
RU2465898C2 (ru) * 2006-10-31 2012-11-10 Алькон Рисерч, Лтд. Модуляторы связывания pai-1 для лечения глазных болезней
WO2008096804A1 (ja) * 2007-02-07 2008-08-14 Teika Pharmaceutical Co., Ltd. ラタノプロスト含有点眼剤
JP2009073788A (ja) * 2007-09-21 2009-04-09 Teika Seiyaku Kk イソプロピルウノプロストン含有眼用組成物
NZ584275A (en) * 2007-10-08 2012-06-29 Fovea Pharmaceuticals Aqueous cyclosporine ophthalmic formulations
ES2638771T3 (es) * 2008-03-17 2017-10-24 Novartis Ag Composiciones farmacéuticas acuosas que contienen complejos de borato-poliol
TWI544927B (zh) * 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
EP2127638A1 (en) 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
RU2402316C2 (ru) * 2009-01-11 2010-10-27 Пшеничников Виталий Георгиевич Фармацевтическая антиглаукомная композиция
US8952051B2 (en) 2009-11-05 2015-02-10 Allergan, Inc. Ophthalmic formulations containing substituted gamma lactams and methods for use thereof
CN103596572A (zh) * 2011-04-12 2014-02-19 株式会社·R-技术上野 水性眼用组合物
US20130029919A1 (en) * 2011-07-26 2013-01-31 Allergan, Inc. Two part formulation system for opthalmic delivery
EP2567689A1 (en) 2011-09-12 2013-03-13 Visiotact Pharma Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
CA2858574C (en) 2011-12-07 2017-05-30 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
NZ732058A (en) 2014-11-25 2023-06-30 Allergan Inc Stabilized omega-3 ophthalmic compositions
AU2019343188A1 (en) * 2018-09-21 2021-05-20 Aufbau Medical Innovations Limited Compositions and methods for glaucoma
AU2020272127B2 (en) 2019-04-12 2022-12-08 Ecolab Usa Inc. Antimicrobial multi-purpose cleaner and methods of making and using the same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0458587A1 (en) * 1990-05-22 1991-11-27 R-Tech Ueno Ltd. Synergistic combination for ophthalmic use
WO1992013836A1 (en) * 1991-02-07 1992-08-20 Allergan, Inc. 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5767154A (en) * 1991-02-07 1998-06-16 Allergan 5-trans-prostaglandins of the F series and their use as ocular hypotensives
EP0708646A1 (en) * 1994-05-06 1996-05-01 Alcon Laboratories, Inc. Use of vitamin e tocopheryl derivatives in ophthalmic compositions
US5631287A (en) † 1994-12-22 1997-05-20 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0458587A1 (en) * 1990-05-22 1991-11-27 R-Tech Ueno Ltd. Synergistic combination for ophthalmic use
WO1992013836A1 (en) * 1991-02-07 1992-08-20 Allergan, Inc. 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101382922B1 (ko) * 2006-03-13 2014-04-08 가부시키가이샤 아루떼꾸 우에노 수성 조성물

Also Published As

Publication number Publication date
CA2280089C (en) 2009-03-03
HUP0002194A2 (hu) 2000-12-28
CN1249687A (zh) 2000-04-05
PE61899A1 (es) 1999-06-30
EP0969846B2 (en) 2010-08-25
DE69820997D1 (de) 2004-02-12
TW527187B (en) 2003-04-11
HK1026841A1 (en) 2000-12-29
JP2010043110A (ja) 2010-02-25
DE69820997T3 (de) 2011-10-06
NZ337322A (en) 2001-05-25
ATE257385T1 (de) 2004-01-15
SI0969846T2 (sl) 2010-12-31
CA2280089A1 (en) 1998-09-24
JP4920124B2 (ja) 2012-04-18
SI0969846T1 (en) 2004-06-30
PL197509B1 (pl) 2008-04-30
DE69820997T2 (de) 2004-12-09
KR20000076330A (ko) 2000-12-26
EE04091B1 (et) 2003-08-15
EP0969846A1 (en) 2000-01-12
UA63938C2 (uk) 2004-02-16
CZ299833B6 (cs) 2008-12-10
AR011192A1 (es) 2000-08-02
AR002194A1 (es) 1998-01-07
CY2526B1 (en) 2006-02-08
NO994481L (no) 1999-09-16
ID22389A (id) 1999-10-07
WO1998041208A1 (en) 1998-09-24
AU738781B2 (en) 2001-09-27
NO994481D0 (no) 1999-09-16
ES2214706T3 (es) 2004-09-16
MY122237A (en) 2006-04-29
JP2001515502A (ja) 2001-09-18
DK0969846T4 (da) 2010-12-20
BRPI9816218B1 (pt) 2016-04-12
AU7035398A (en) 1998-10-12
CZ325799A3 (cs) 2000-01-12
HUP0002194A3 (en) 2012-08-28
ES2214706T5 (es) 2011-02-02
PT969846E (pt) 2004-05-31
BR9808016A (pt) 2000-03-08
NO327713B1 (no) 2009-09-14
RU2197970C2 (ru) 2003-02-10
CO4940427A1 (es) 2000-07-24
CN1236775C (zh) 2006-01-18
ZA982188B (en) 1998-09-17
EP0969846B1 (en) 2004-01-07
IL131041A0 (en) 2001-01-28
CL2009001870A1 (es) 2010-01-22
HU228896B1 (en) 2013-06-28
PL335168A1 (en) 2000-04-10
DK0969846T3 (da) 2004-04-13
EE9900410A (et) 2000-04-17

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