PE20141678A1 - Indazol-3-carboxamidas y su uso como inhibidores de la ruta de senalizacion de wnt/b-catenina - Google Patents

Indazol-3-carboxamidas y su uso como inhibidores de la ruta de senalizacion de wnt/b-catenina

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Publication number
PE20141678A1
PE20141678A1 PE2014000356A PE2014000356A PE20141678A1 PE 20141678 A1 PE20141678 A1 PE 20141678A1 PE 2014000356 A PE2014000356 A PE 2014000356A PE 2014000356 A PE2014000356 A PE 2014000356A PE 20141678 A1 PE20141678 A1 PE 20141678A1
Authority
PE
Peru
Prior art keywords
alkyl
indazol
wnt
carboxamides
inhibitors
Prior art date
Application number
PE2014000356A
Other languages
English (en)
Spanish (es)
Inventor
John Hood
Sunil Kumar Kc
Original Assignee
Samumed Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samumed Llc filed Critical Samumed Llc
Publication of PE20141678A1 publication Critical patent/PE20141678A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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PE2014000356A 2011-09-14 2012-09-13 Indazol-3-carboxamidas y su uso como inhibidores de la ruta de senalizacion de wnt/b-catenina PE20141678A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161534601P 2011-09-14 2011-09-14
US201261624646P 2012-04-16 2012-04-16

Publications (1)

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PE20141678A1 true PE20141678A1 (es) 2014-11-21

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US (6) US9221793B2 (OSRAM)
EP (2) EP3473099A1 (OSRAM)
JP (2) JP2014526510A (OSRAM)
KR (1) KR102010611B1 (OSRAM)
CN (2) CN103929963A (OSRAM)
AU (2) AU2012308570B2 (OSRAM)
BR (1) BR112014006127A2 (OSRAM)
CA (1) CA2848659C (OSRAM)
CL (1) CL2014000642A1 (OSRAM)
CO (1) CO6940416A2 (OSRAM)
CY (1) CY1122795T1 (OSRAM)
DK (1) DK2755483T3 (OSRAM)
ES (1) ES2711777T3 (OSRAM)
HR (1) HRP20190281T1 (OSRAM)
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