SG10202002005SA - Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors - Google Patents

Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors

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Publication number
SG10202002005SA
SG10202002005SA SG10202002005SA SG10202002005SA SG10202002005SA SG 10202002005S A SG10202002005S A SG 10202002005SA SG 10202002005S A SG10202002005S A SG 10202002005SA SG 10202002005S A SG10202002005S A SG 10202002005SA SG 10202002005S A SG10202002005S A SG 10202002005SA
Authority
SG
Singapore
Prior art keywords
wnt
carboxamides
indazole
signaling pathway
pathway inhibitors
Prior art date
Application number
SG10202002005SA
Inventor
John Hood
Sunil Kumar Kc
Original Assignee
Samumed Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samumed Llc filed Critical Samumed Llc
Publication of SG10202002005SA publication Critical patent/SG10202002005SA/en

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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SG10202002005SA 2011-09-14 2012-09-13 Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors SG10202002005SA (en)

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US201161534601P 2011-09-14 2011-09-14
US201261624646P 2012-04-16 2012-04-16

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SG11201400666PA SG11201400666PA (en) 2011-09-14 2012-09-13 Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors

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US (6) US9221793B2 (en)
EP (2) EP3473099A1 (en)
JP (2) JP2014526510A (en)
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