PE20060425A1 - Formulacion de tableta revestida que comprende saxagliptina - Google Patents
Formulacion de tableta revestida que comprende saxagliptinaInfo
- Publication number
- PE20060425A1 PE20060425A1 PE2005000601A PE2005000601A PE20060425A1 PE 20060425 A1 PE20060425 A1 PE 20060425A1 PE 2005000601 A PE2005000601 A PE 2005000601A PE 2005000601 A PE2005000601 A PE 2005000601A PE 20060425 A1 PE20060425 A1 PE 20060425A1
- Authority
- PE
- Peru
- Prior art keywords
- coated
- coating
- coated tablet
- tablet formulation
- degradation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
SE REFIERE A UNA FORMULACION DE TABLETA REVESTIDA, LA CUAL INCLUYE UN NUCLEO DE TABLETA CONFORMADO POR UNO O MAS AGENTES DE VOLUMEN O LLENADORES Y OPCIONALMENTE AGLUTINANTES, DESINTEGRANTES Y/O LUBRICANTES, EL CUAL ES REVESTIDO POR: a) UNA CAPA DE REVESTIMIENTO DE SELLO INTERNO CONSTITUIDO POR UN POLIMERO DE REVESTIMIENTO PREFERIBLEMENTE BASADO EN ALCOHOL POLIVINILICO (PVA); b) UNA SEGUNDA CAPA DE REVESTIMIENTO DISPUESTA SOBRE LA CUBIERTA DE SELLO INTERNO, CONFORMADA POR UN MEDICAMENTO: SAXAGLIPTINA (INHIBIDOR DE DIPEPTIDIL PEPTIDASA-4 DPP4) EL CUAL ES ESTABLE Y PUEDE SER SOMETIDO A DEGRADACION, Y AL MENOS UN POLIMERO DE REVESTIMIENTO, EL CUAL ES PREFERIBLEMENTE EL MISMO DE LA CUBIERTA ANTERIOR; Y OPCIONALMENTE c) UNA CAPA DE REVESTIMIENTO PROTECTORA EXTERIOR DISPUESTA SOBRE LA SEGUNDA CAPA DE REVESTIMIENTO FORMADA POR AL MENOS UN POLIMERO EL CUAL ES PREFERIBLEMENTE EL MISMO POLIMERO DE REVESTIMIENTO UTILIZADO EN LAS ANTERIORES CAPAS. TAMBIEN SE REFIERE A UN PROCESO DE ELABORACION DE LA TABLETA REVESTIDA, EL CUAL ES UTIL PARA EL TRATAMIENTO DE DIABETES MELLITUS TIPO 2
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57531904P | 2004-05-28 | 2004-05-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20060425A1 true PE20060425A1 (es) | 2006-06-01 |
Family
ID=34971747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2005000601A PE20060425A1 (es) | 2004-05-28 | 2005-05-30 | Formulacion de tableta revestida que comprende saxagliptina |
Country Status (33)
Country | Link |
---|---|
US (4) | US7951400B2 (es) |
EP (3) | EP3078369B1 (es) |
JP (1) | JP4901727B2 (es) |
KR (2) | KR20120064141A (es) |
CN (2) | CN1988891B (es) |
AR (2) | AR049062A1 (es) |
AU (1) | AU2005249467B2 (es) |
BR (1) | BRPI0510419B8 (es) |
CA (1) | CA2568391C (es) |
CY (2) | CY1117813T1 (es) |
DK (2) | DK1753406T4 (es) |
ES (3) | ES2582646T5 (es) |
GE (1) | GEP20094639B (es) |
HK (2) | HK1155399A1 (es) |
HR (2) | HRP20160880T4 (es) |
HU (2) | HUE029446T2 (es) |
IL (2) | IL179454A (es) |
LT (1) | LT2298288T (es) |
ME (2) | ME02516B (es) |
MX (1) | MXPA06013711A (es) |
MY (1) | MY147639A (es) |
NO (1) | NO343907B1 (es) |
NZ (1) | NZ551591A (es) |
PE (1) | PE20060425A1 (es) |
PL (2) | PL1753406T5 (es) |
PT (2) | PT1753406E (es) |
RS (2) | RS54929B2 (es) |
RU (1) | RU2372894C2 (es) |
SI (3) | SI1753406T2 (es) |
TW (2) | TWI415635B (es) |
UA (1) | UA88168C2 (es) |
WO (1) | WO2005117841A1 (es) |
ZA (1) | ZA200609541B (es) |
Families Citing this family (127)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0487425A (ja) * | 1990-07-31 | 1992-03-19 | Fujitsu Ltd | 回線切り替え装置 |
CN100408579C (zh) * | 2001-02-24 | 2008-08-06 | 贝林格尔英格海姆法玛两合公司 | 黄嘌呤衍生物,其制法及其作为药物组合物的用途 |
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
DK1712547T3 (da) * | 2004-02-05 | 2012-03-19 | Kyorin Seiyaku Kk | Bicycloesterderivat |
US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
TW200534879A (en) * | 2004-03-25 | 2005-11-01 | Bristol Myers Squibb Co | Coated tablet formulation and method |
US7829720B2 (en) * | 2004-05-04 | 2010-11-09 | Bristol-Myers Squibb Company | Process for preparing atazanavir bisulfate and novel forms |
US20050256314A1 (en) * | 2004-05-04 | 2005-11-17 | Soojin Kim | Process employing controlled crystallization in forming crystals of a pharmaceutical |
TWI415635B (zh) | 2004-05-28 | 2013-11-21 | 必治妥施貴寶公司 | 加衣錠片調製物及製備彼之方法 |
DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
GB0526291D0 (en) * | 2005-12-23 | 2006-02-01 | Prosidion Ltd | Therapeutic method |
SI1818057T1 (sl) * | 2006-02-09 | 2010-08-31 | Teva Pharma | Stabilne farmacevtske formulacije montelukast natrija |
EP1995237A4 (en) * | 2006-03-08 | 2011-07-06 | Kyorin Seiyaku Kk | PROCESS FOR PREPARING AN AMINOACETYLPYRROLIDINCARBONITRILE DERIVATIVE AND PRODUCTION PRODUCT THEREOF |
EA015687B1 (ru) | 2006-05-04 | 2011-10-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Полиморфы |
EP1852108A1 (en) * | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
US20070172525A1 (en) * | 2007-03-15 | 2007-07-26 | Ramesh Sesha | Anti-diabetic combinations |
US20080064701A1 (en) * | 2007-04-24 | 2008-03-13 | Ramesh Sesha | Anti-diabetic combinations |
ATE550319T1 (de) * | 2007-03-22 | 2012-04-15 | Kyorin Seiyaku Kk | Verfahren zur herstellung eines aminoacetylpyrrolidincarbonitrilderivats |
PE20090185A1 (es) | 2007-03-22 | 2009-02-28 | Bristol Myers Squibb Co | Formulaciones farmaceuticas que contienen un inhibidor sglt2 |
PE20090696A1 (es) * | 2007-04-20 | 2009-06-20 | Bristol Myers Squibb Co | Formas cristalinas de saxagliptina y procesos para preparar las mismas |
AU2008268537B2 (en) * | 2007-06-22 | 2012-11-01 | Bristol-Myers Squibb Holdings Ireland | Tableted compositions containing atazanavir |
KR20100033379A (ko) * | 2007-06-22 | 2010-03-29 | 브리스톨-마이어스 스큅 컴퍼니 | 아타자나비르를 함유하는 정제 조성물 |
AU2008268625B2 (en) * | 2007-06-22 | 2013-11-28 | Bristol-Myers Squibb Holdings Ireland Unlimited Company | Tableted compositions containing atazanavir |
EP2178511B1 (en) * | 2007-06-22 | 2011-03-02 | Bristol-Myers Squibb Company | Tableted compositions containing atazanavir |
EP2175740B1 (en) * | 2007-07-31 | 2018-06-06 | Cargill, Incorporated | Direct compressible dextrose |
CA2923102C (en) | 2007-08-13 | 2019-10-15 | Abuse Deterrent Pharmaceutical Llc | Abuse resistant drugs, method of use and method of making |
CL2008002427A1 (es) | 2007-08-16 | 2009-09-11 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2. |
US8551524B2 (en) * | 2008-03-14 | 2013-10-08 | Iycus, Llc | Anti-diabetic combinations |
AR071175A1 (es) | 2008-04-03 | 2010-06-02 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante |
IT1393244B1 (it) * | 2008-07-18 | 2012-04-12 | Universita' Degli Studi Di Milano | Sistema per il rilascio al colon di farmaci suscettibili di degradazione enzimatica e/o scarsamente assorbiti nel tratto gastrointestinale |
KR20190016601A (ko) | 2008-08-06 | 2019-02-18 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
WO2010016584A1 (ja) * | 2008-08-07 | 2010-02-11 | 杏林製薬株式会社 | ビシクロ[2.2.2]オクチルアミン誘導体の製造方法 |
EP2331080A4 (en) * | 2008-08-12 | 2012-11-07 | Inspirion Delivery Technologies Llc | PHARMACEUTICAL COMPOSITIONS CONFIGURED TO DISSUATE FRACTIONATION OF DOSAGE FORMS |
CN102186474A (zh) * | 2008-08-14 | 2011-09-14 | 杏林制药株式会社 | 稳定的医药组合物 |
CN103816158A (zh) | 2008-08-15 | 2014-05-28 | 勃林格殷格翰国际有限公司 | 用于治疗fab-相关疾病的嘌呤衍生物 |
CA2736421A1 (en) | 2008-09-10 | 2010-03-18 | Boehringer Ingelheim International Gmbh | Combination therapy for the treatment of diabetes and related conditions |
US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
DE102008059206A1 (de) | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum |
CN107011345A (zh) | 2008-12-23 | 2017-08-04 | 勃林格殷格翰国际有限公司 | 有机化合物的盐形式 |
AR074990A1 (es) | 2009-01-07 | 2011-03-02 | Boehringer Ingelheim Int | Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina |
TWI466672B (zh) | 2009-01-29 | 2015-01-01 | Boehringer Ingelheim Int | 小兒科病人糖尿病之治療 |
CN106177958A (zh) | 2009-02-13 | 2016-12-07 | 勃林格殷格翰国际有限公司 | 包含dpp‑4抑制剂(利拉列汀)任选地组合其它抗糖尿病药的抗糖尿病药物 |
UY32441A (es) | 2009-02-13 | 2010-09-30 | Boehringer Ingelheim Int | Composicion farmaceutica, metodos de tratamiento y sus usos |
WO2010110436A1 (ja) | 2009-03-27 | 2010-09-30 | 杏林製薬株式会社 | 塩基性添加剤を含有するマトリックス型徐放性製剤 |
SG10201501882TA (en) | 2009-03-27 | 2015-06-29 | Astrazeneca Ab | Methods for preventing major adverse cardiovascular events with dpp-iv inhibitors |
KR20120006047A (ko) | 2009-04-09 | 2012-01-17 | 산도즈 아게 | 삭사글립틴의 결정 형태 |
DK2498758T3 (en) | 2009-11-13 | 2018-10-15 | Astrazeneca Ab | TWO-LAYER TABLET FORMULATIONS |
DK2498759T3 (en) * | 2009-11-13 | 2018-11-26 | Astrazeneca Ab | TABLE FORMULATIONS WITH IMMEDIATE RELEASE |
EA034869B1 (ru) | 2009-11-27 | 2020-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Лечение генотипированных пациентов с диабетом ингибиторами дпп-4, такими как линаглиптин |
WO2011113947A1 (en) | 2010-03-18 | 2011-09-22 | Boehringer Ingelheim International Gmbh | Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions |
CN102210693B (zh) * | 2010-04-10 | 2013-10-09 | 山东新华制药股份有限公司 | 一种阿司匹林和双嘧达莫多层片的制备方法 |
EP2566469B1 (en) | 2010-05-05 | 2022-12-21 | Boehringer Ingelheim International GmbH | Combination therapy |
JP5373996B2 (ja) | 2010-05-05 | 2013-12-18 | アッシア・ケミカル・インダストリーズ・リミテッド | サクサグリプチン中間体、サクサグリプチン多形及びそれらの調製方法 |
CN102971005A (zh) | 2010-06-24 | 2013-03-13 | 贝林格尔.英格海姆国际有限公司 | 糖尿病治疗 |
WO2012017029A1 (en) | 2010-08-06 | 2012-02-09 | Sandoz Ag | Novel salts of saxagrliptin with organic di-acids |
WO2012017028A1 (en) | 2010-08-06 | 2012-02-09 | Sandoz Ag | A novel crystalline compound comprising saxagliptin and phosphoric acid |
KR20130137624A (ko) | 2010-09-03 | 2013-12-17 | 브리스톨-마이어스 스큅 컴퍼니 | 수용성 항산화제를 사용한 약물 제제 |
WO2012047871A1 (en) | 2010-10-04 | 2012-04-12 | Assia Chemical Industries Ltd | Polymorphs of saxagliptin hydrochloride and processes for preparing them |
DK2637668T3 (en) | 2010-11-08 | 2016-08-29 | Albireo Ab | Ibat inhibitors for the treatment of liver diseases |
US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
CN102086172A (zh) * | 2011-01-13 | 2011-06-08 | 廖国超 | 沙格列汀的药用盐及其制备方法 |
RU2607480C2 (ru) * | 2011-02-01 | 2017-01-10 | Бристол-Майерс Сквибб Компани | Фармацевтические композиции, содержащие аминосоединение |
EP2731947B1 (en) | 2011-07-15 | 2019-01-16 | Boehringer Ingelheim International GmbH | Substituted dimeric quinazoline derivative, its preparation and its use in pharmaceutical compositions for the treatment of type i and ii diabetes |
EP2741736B1 (en) | 2011-08-12 | 2017-11-22 | Boehringer Ingelheim Vetmedica GmbH | Taste masked pharmaceutical composition |
US20140302150A1 (en) | 2011-09-07 | 2014-10-09 | Umit Cifter | Dpp-iv inhibitor formulations |
US9446000B2 (en) | 2011-09-08 | 2016-09-20 | Masdar Institute Of Science And Technology | Cellulosic gel material as a pharmaceutical excipient |
ES2487271T3 (es) | 2011-10-06 | 2014-08-20 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Formulaciones de dosificación sólidas inhibidoras de DPP-IV |
US20130189358A1 (en) | 2012-01-10 | 2013-07-25 | Roey Solomonovich | Saxagliptin pharmaceutical formulations |
WO2013130785A2 (en) | 2012-03-01 | 2013-09-06 | Bristol-Myers Squibb Company | Extended release pharmaceutical formulations of water-soluble active pharmaceutical ingredients and methods for making the same |
US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
BR112014027618A2 (pt) | 2012-05-07 | 2017-06-27 | Bayer Pharma AG | processo para a fabricação de uma forma de dosagem farmacêutica compreendendo nifedipina e candesartan cilexetil |
JP6224084B2 (ja) | 2012-05-14 | 2017-11-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 糸球体上皮細胞関連障害及び/又はネフローゼ症候群の治療に用いるdpp−4阻害薬としてのキサンチン誘導体 |
WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
WO2013179307A2 (en) * | 2012-05-29 | 2013-12-05 | Mylan Laboratories Limited | Stabilized pharmaceutical compositions of saxagliptin |
WO2014030051A1 (en) | 2012-08-23 | 2014-02-27 | Aurobindo Pharma Limited | Stable pharmaceutical compositions comprising saxagliptin |
WO2014065427A1 (ja) * | 2012-10-26 | 2014-05-01 | 株式会社 三和化学研究所 | アナグリプチン含有固形製剤 |
WO2014096982A1 (en) | 2012-12-21 | 2014-06-26 | Wockhardt Limited | Stable pharmaceutical compositions of saxagliptin or salts thereof |
WO2014096983A1 (en) | 2012-12-21 | 2014-06-26 | Wockhardt Limited | Stable pharmaceutical compositions of saxagliptin or salts thereof |
WO2014146093A2 (en) | 2013-03-15 | 2014-09-18 | Inspirion Delivery Technologies, Llc | Abuse deterrent compositions and methods of use |
WO2014193528A1 (en) * | 2013-04-29 | 2014-12-04 | Anovel Pharmaceuticals, Llc | Amorphous dosage forms and methods |
CN103316056B (zh) * | 2013-06-24 | 2015-07-08 | 江苏鹏鹞药业有限公司 | 一种板蓝根包衣分散片及其制备方法 |
WO2015071889A1 (en) | 2013-11-18 | 2015-05-21 | Ranbaxy Laboratories Limited | Oral compositions of saxagliptin |
WO2015071887A1 (en) | 2013-11-18 | 2015-05-21 | Ranbaxy Laboratories Limited | Oral pharmaceutical compositions of saxagliptin |
CN105916598B (zh) * | 2014-01-21 | 2020-07-17 | Bpsi控股有限责任公司 | 含有中链甘油酯的即释型膜包衣及用其包被的基质 |
JP6615109B2 (ja) | 2014-02-28 | 2019-12-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Dpp−4阻害薬の医学的使用 |
US10709755B2 (en) * | 2014-06-25 | 2020-07-14 | Elobix Ab | Solid formulation and method for preventing or reducing coloration thereof |
US10729685B2 (en) | 2014-09-15 | 2020-08-04 | Ohemo Life Sciences Inc. | Orally administrable compositions and methods of deterring abuse by intranasal administration |
CN105520913B (zh) * | 2014-09-28 | 2020-06-23 | 石药集团中奇制药技术(石家庄)有限公司 | 一种包含沙格列汀的微丸、其用途及其制备方法 |
CN105497023B (zh) * | 2014-10-15 | 2021-05-25 | 北京福元医药股份有限公司 | 一种沙格列汀药物制剂 |
EP3012252A1 (en) | 2014-10-24 | 2016-04-27 | Ferring BV | Crystal modifications of elobixibat |
CN104557943B (zh) * | 2014-12-23 | 2017-05-03 | 扬子江药业集团四川海蓉药业有限公司 | 一种维格列汀杂质的制备方法 |
CN105796503B (zh) * | 2014-12-30 | 2019-05-07 | 深圳翰宇药业股份有限公司 | 一种沙格列汀微丸及其制剂 |
CN104672243B (zh) * | 2015-02-10 | 2017-09-22 | 华润赛科药业有限责任公司 | 维格列汀降解杂质的制备方法 |
KR20170132325A (ko) | 2015-04-02 | 2017-12-01 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | 뮤 오피오이드 수용체 길항제 및 오피오이드 제제의 조합 제형 |
CN106176661B (zh) * | 2015-04-29 | 2019-02-01 | 四川科伦药物研究院有限公司 | 一种沙格列汀或其盐的胶囊及其制备方法 |
KR20180021814A (ko) * | 2015-06-30 | 2018-03-05 | 제넨테크, 인크. | 약물을 포함하는 속방성 정제 및 상기 정제의 형성 공정 |
CN106924207A (zh) * | 2015-12-31 | 2017-07-07 | 深圳翰宇药业股份有限公司 | 一种维格列汀片剂及其制备方法 |
US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
WO2017211979A1 (en) | 2016-06-10 | 2017-12-14 | Boehringer Ingelheim International Gmbh | Combinations of linagliptin and metformin |
EP3664781A1 (en) | 2017-08-09 | 2020-06-17 | Albireo AB | Cholestyramine granules, oral cholestyramine formulations and use thereof |
CN108822820B (zh) * | 2018-05-22 | 2020-11-03 | 东莞理工学院 | 一种隔离型水合物动力学抑制胶囊及其制备方法与应用 |
US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
WO2019234077A1 (en) | 2018-06-05 | 2019-12-12 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
SG11202012151XA (en) | 2018-06-20 | 2021-01-28 | Albireo Ab | Crystal modifications of odevixibat |
US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
WO2020098904A1 (en) | 2018-11-12 | 2020-05-22 | Pharmaceutical Oriented Services Ltd | Dosage form containing metformin and a dipeptidyl peptidase iv inhibitor |
US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
CN109999006A (zh) * | 2019-04-28 | 2019-07-12 | 江苏豪森药业集团有限公司 | 沙格列汀包衣片及其制备方法 |
US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
EP4069359B1 (en) | 2019-12-04 | 2024-01-03 | Albireo AB | Benzothia(di)azepine compounds and their use as bile acid modulators |
EP4069361B1 (en) | 2019-12-04 | 2024-01-03 | Albireo AB | Benzothia(di)azepine compounds and their use as bile acid modulators |
JP2023504645A (ja) | 2019-12-04 | 2023-02-06 | アルビレオ・アクチボラグ | ベンゾチア(ジ)アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
CN114761018A (zh) | 2019-12-04 | 2022-07-15 | 阿尔比里奥公司 | 苯并硫杂二氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
JP2022003016A (ja) | 2020-06-23 | 2022-01-11 | 沢井製薬株式会社 | サキサグリプチン含有製剤及びその製造方法 |
EP4188541A1 (en) | 2020-08-03 | 2023-06-07 | Albireo AB | Benzothia(di)azepine compounds and their use as bile acid modulators |
EP4243831A1 (en) | 2020-11-12 | 2023-09-20 | Albireo AB | Odevixibat for treating progressive familial intrahepatic cholestasis (pfic) |
BR112023010799A2 (pt) | 2020-12-04 | 2023-10-03 | Albireo Ab | Compostos de benzotia(di)azepina e seus usos como moduladores de ácidos biliares |
KR20220165346A (ko) | 2021-06-08 | 2022-12-15 | 동아에스티 주식회사 | 에보글립틴의 안정성이 개선된 제제 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3696188A (en) * | 1971-06-16 | 1972-10-03 | Schering Corp | Laminated tablets |
DE3403329A1 (de) * | 1984-02-01 | 1985-08-01 | Horst Dr. 4019 Monheim Zerbe | Pharmazeutisches produkt in form von pellets mit kontinuierlicher, verzoegerter wirkstoffabgabe |
JPS6186211A (ja) | 1984-10-04 | 1986-05-01 | 日本碍子株式会社 | セラミックス複合構造体及びその製造法 |
FR2623810B2 (fr) | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
US5158777A (en) | 1990-02-16 | 1992-10-27 | E. R. Squibb & Sons, Inc. | Captopril formulation providing increased duration of activity |
CA2068402C (en) | 1991-06-14 | 1998-09-22 | Michael R. Hoy | Taste mask coatings for preparation of chewable pharmaceutical tablets |
US5428048A (en) | 1993-11-08 | 1995-06-27 | American Home Products Corporation | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents |
GB9407386D0 (en) | 1994-04-14 | 1994-06-08 | Smithkline Beecham Plc | Pharmaceutical formulation |
TW483763B (en) * | 1994-09-02 | 2002-04-21 | Astra Ab | Pharmaceutical composition comprising of ramipril and dihydropyridine compound |
US5849911A (en) | 1996-04-22 | 1998-12-15 | Novartis Finance Corporation | Antivirally active heterocyclic azahexane derivatives |
TW522014B (en) | 1997-02-07 | 2003-03-01 | Sepracor Inc | Lactose-free, non-hygroscopic and anhydrous pharmaceutical unit dosage form containing descarboethoxyloratadine |
GB9715896D0 (en) | 1997-07-28 | 1997-10-01 | Sca Packaging Ltd | Containers |
US6087383A (en) | 1998-01-20 | 2000-07-11 | Bristol-Myers Squibb Company | Bisulfate salt of HIV protease inhibitor |
US20010055613A1 (en) * | 1998-10-21 | 2001-12-27 | Beth A. Burnside | Oral pulsed dose drug delivery system |
WO2000056719A1 (en) | 1999-03-22 | 2000-09-28 | Bristol-Myers Squibb Company | FUSED PYRIDOPYRIDAZINE INHIBITORS OF cGMP PHOSPHODIESTERASE |
US6414002B1 (en) | 1999-09-22 | 2002-07-02 | Bristol-Myers Squibb Company | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method |
WO2001034148A1 (fr) | 1999-11-11 | 2001-05-17 | Kyorin Pharmaceutical Co., Ltd. | Preparations solides pour administration orale |
US6569456B2 (en) * | 2000-01-13 | 2003-05-27 | Osmotica Corp. | Osmotic device containing diltiazem and an ACE inhibitor or diuretic |
AU2001237321A1 (en) | 2000-01-21 | 2001-07-31 | Novartis Ag | Combinations comprising dipeptidylpeptidase - iv inhibitor |
US6254888B1 (en) | 2000-01-28 | 2001-07-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for coating pharmaceutical dosage forms |
US6395767B2 (en) | 2000-03-10 | 2002-05-28 | Bristol-Myers Squibb Company | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method |
IL145106A0 (en) | 2000-08-30 | 2002-06-30 | Pfizer Prod Inc | Intermittent administration of a geowth hormone secretagogue |
US6670344B2 (en) | 2000-09-14 | 2003-12-30 | Bristol-Myers Squibb Company | Combretastatin A-4 phosphate prodrug mono- and di-organic amine salts, mono- and di- amino acid salts, and mono- and di-amino acid ester salts |
US6867300B2 (en) | 2000-11-17 | 2005-03-15 | Bristol-Myers Squibb Company | Methods for the preparation of pyrrolotriazine compounds useful as kinase inhibitors |
US6670334B2 (en) | 2001-01-05 | 2003-12-30 | University Of Virginia Patent Foundation | Method and compositions for treating the inflammatory response |
JP2004530676A (ja) | 2001-04-18 | 2004-10-07 | ノストラム・ファーマスーティカルズ・インコーポレイテッド | 持続放出性薬学的組成物のための新規コーティング |
US20030035839A1 (en) * | 2001-05-15 | 2003-02-20 | Peirce Management, Llc | Pharmaceutical composition for both intraoral and oral administration |
EP1467717A1 (en) | 2002-01-15 | 2004-10-20 | Ranbaxy Laboratories Limited | Stable pharmaceutical compositions comprising ace inhibitor(s) |
KR100456833B1 (ko) | 2002-08-01 | 2004-11-10 | 주식회사 대웅 | 아목시실린 및 클라불라네이트를 함유하는 유핵정 |
US7670624B2 (en) | 2004-01-29 | 2010-03-02 | Astella Pharma Inc. | Gastrointestinal-specific multiple drug release system |
TW200534879A (en) | 2004-03-25 | 2005-11-01 | Bristol Myers Squibb Co | Coated tablet formulation and method |
US20050256314A1 (en) | 2004-05-04 | 2005-11-17 | Soojin Kim | Process employing controlled crystallization in forming crystals of a pharmaceutical |
US7829720B2 (en) | 2004-05-04 | 2010-11-09 | Bristol-Myers Squibb Company | Process for preparing atazanavir bisulfate and novel forms |
US20050288343A1 (en) | 2004-05-19 | 2005-12-29 | Andrew Rusowicz | Process of preparing substituted carbamates and intermediates thereof |
TWI415635B (zh) | 2004-05-28 | 2013-11-21 | 必治妥施貴寶公司 | 加衣錠片調製物及製備彼之方法 |
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