OA11383A - Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters. - Google Patents
Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters. Download PDFInfo
- Publication number
- OA11383A OA11383A OA1200000146A OA1200000146A OA11383A OA 11383 A OA11383 A OA 11383A OA 1200000146 A OA1200000146 A OA 1200000146A OA 1200000146 A OA1200000146 A OA 1200000146A OA 11383 A OA11383 A OA 11383A
- Authority
- OA
- OAPI
- Prior art keywords
- composition
- agent
- composition according
- disorders
- hydroxyrisperidone
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
- Y10S977/775—Nanosized powder or flake, e.g. nanosized catalyst
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97203568 | 1997-11-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
OA11383A true OA11383A (en) | 2004-01-27 |
Family
ID=8228929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA1200000146A OA11383A (en) | 1997-11-17 | 2000-05-17 | Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters. |
Country Status (35)
Country | Link |
---|---|
US (3) | US6555544B2 (fr) |
EP (1) | EP1033987B1 (fr) |
JP (1) | JP4211965B2 (fr) |
KR (1) | KR100365077B1 (fr) |
CN (1) | CN1160074C (fr) |
AP (1) | AP1228A (fr) |
AR (1) | AR016686A1 (fr) |
AT (1) | ATE239480T1 (fr) |
AU (1) | AU745540B2 (fr) |
BG (1) | BG64747B1 (fr) |
BR (1) | BR9814202A (fr) |
CA (1) | CA2309629C (fr) |
CZ (1) | CZ299107B6 (fr) |
DE (1) | DE69814451T2 (fr) |
DK (1) | DK1033987T3 (fr) |
EA (1) | EA002926B1 (fr) |
EE (1) | EE04144B1 (fr) |
ES (1) | ES2199481T3 (fr) |
HK (1) | HK1029045A1 (fr) |
HR (1) | HRP20000289B1 (fr) |
HU (1) | HU226070B1 (fr) |
ID (1) | ID24981A (fr) |
IL (1) | IL136135A (fr) |
MY (1) | MY117810A (fr) |
NO (1) | NO320384B1 (fr) |
NZ (1) | NZ503295A (fr) |
OA (1) | OA11383A (fr) |
PL (1) | PL192203B1 (fr) |
PT (1) | PT1033987E (fr) |
SI (1) | SI1033987T1 (fr) |
SK (1) | SK285126B6 (fr) |
TR (1) | TR200001282T2 (fr) |
UA (1) | UA72189C2 (fr) |
WO (1) | WO1999025354A2 (fr) |
ZA (1) | ZA9810467B (fr) |
Families Citing this family (64)
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UA72189C2 (uk) * | 1997-11-17 | 2005-02-15 | Янссен Фармацевтика Н.В. | Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот |
EP1227806B1 (fr) * | 1999-11-11 | 2005-08-03 | Pfizer Health AB | Formulation pharmaceutique contenant de la tolterodine et son utilisation |
GB0003048D0 (en) * | 2000-02-11 | 2000-03-29 | Dealler Stephen F | The therapeutic use of polysulphonated polyglycosides or other polyanionic compounds in autism |
JP4848575B2 (ja) * | 2000-03-30 | 2011-12-28 | ゼリア新薬工業株式会社 | アラントインを配合した安定な液剤 |
US6495164B1 (en) | 2000-05-25 | 2002-12-17 | Alkermes Controlled Therapeutics, Inc. I | Preparation of injectable suspensions having improved injectability |
MXPA03006565A (es) * | 2001-01-23 | 2005-07-29 | Gador Sa | Composicion comprendiendo bisfosfonatos para la prevencion y/o tratamiento de enfermedades metabolicas de huesos, proceso para preparar tal composicion y el uso de la misma. |
US7097868B2 (en) * | 2001-08-23 | 2006-08-29 | Bio-Dar Ltd. | Stable coated microcapsules |
CN101912367A (zh) * | 2001-10-30 | 2010-12-15 | 诺瓦提斯公司 | 伊潘立酮和星状聚合物的贮库制剂 |
GB0216416D0 (en) * | 2002-07-15 | 2002-08-21 | Novartis Ag | Organic compounds |
JP4776229B2 (ja) * | 2002-07-16 | 2011-09-21 | エラン ファーマ インターナショナル,リミティド | 安定なナノ粒子活性物質の液体投与組成物 |
JP2006505579A (ja) * | 2002-10-25 | 2006-02-16 | ファイザー・プロダクツ・インク | 懸濁形態でのアリール複素環活性薬物の蓄積製剤 |
KR20080093464A (ko) * | 2003-09-02 | 2008-10-21 | 화이자 프로덕츠 인크. | 지프라시돈 나노입자 |
US20050064045A1 (en) * | 2003-09-18 | 2005-03-24 | Sheng-Ping Zhong | Injectable therapeutic formulations |
US7906125B2 (en) | 2003-09-18 | 2011-03-15 | Boston Scientific Scimed, Inc. | Solid or semi-solid therapeutic formulations |
GB0322994D0 (en) * | 2003-10-01 | 2003-11-05 | Novartis Ag | Organic compounds |
GEP20115205B (en) | 2003-10-23 | 2011-04-26 | Otsuka Pharma Co Ltd | Controlled release sterile injectable aripiprazole formulation and method |
US20080305161A1 (en) * | 2005-04-13 | 2008-12-11 | Pfizer Inc | Injectable depot formulations and methods for providing sustained release of nanoparticle compositions |
CA2603189A1 (fr) * | 2005-04-13 | 2006-10-19 | Pfizer Products Inc. | Formulations de depot injectables et procedes destines a assurer une liberation prolongee de medicaments peu solubles comprenant des nanoparticules |
WO2006114384A1 (fr) * | 2005-04-25 | 2006-11-02 | Janssen Pharmaceutica N.V. | Preparation d'ester de 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4h-pyridio[1,2-a]pyrimidin-4-one palmitate aseptique |
US8263109B2 (en) | 2005-05-09 | 2012-09-11 | Boston Scientific Scimed, Inc. | Injectable bulking compositions |
US20060251581A1 (en) * | 2005-05-09 | 2006-11-09 | Mcintyre Jon T | Method for treatment of uterine fibroid tumors |
US7862552B2 (en) * | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
AR055099A1 (es) * | 2005-07-28 | 2007-08-08 | Alza Corp | Formulaciones liquidas para la administracion controlada de derivados de bencisoxazol |
US20080166411A1 (en) * | 2006-04-10 | 2008-07-10 | Pfizer Inc | Injectable Depot Formulations And Methods For Providing Sustained Release Of Poorly Soluble Drugs Comprising Nanoparticles |
BRPI0713334B1 (pt) * | 2006-06-23 | 2024-02-20 | Janssen Sciences Ireland Uc | Uso de 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]-amino]-2-pirimidinil]-amino]-benzonitrila para tratar ou prevenir infecção por HIV |
DK2154138T3 (en) | 2007-04-19 | 2015-11-02 | Youxin Li | Novel compounds for the treatment of psychotic disorders, methods of preparation and uses thereof |
WO2009026621A1 (fr) * | 2007-08-29 | 2009-03-05 | Alphapharm Pty Ltd | Composé et composition pharmaceutiques |
PL2234617T3 (pl) * | 2007-12-19 | 2021-11-08 | Janssen Pharmaceutica Nv | Schemat dawkowania związany z długodziałającymi estrami paliperydonu do wstrzykiwań |
ES2833035T3 (es) * | 2009-07-31 | 2021-06-14 | Ascendis Pharma As | Hidrogeles biodegradables insolubles en agua a base de polietilenglicol |
AU2010277559B2 (en) | 2009-07-31 | 2016-08-11 | Sanofi-Aventis Deutschland Gmbh | Prodrugs comprising an insulin linker conjugate |
UA108475C2 (uk) | 2009-07-31 | 2015-05-12 | Санофі-Авентіс Дойчланд Гмбх | Композиція інсуліну тривалої дії |
WO2011042453A1 (fr) * | 2009-10-06 | 2011-04-14 | Ascendis Pharma As | Composition sous-cutanée de palipéridone |
WO2011042450A1 (fr) * | 2009-10-06 | 2011-04-14 | Ascendis Pharma As | Promédicaments à base de palipéridone liée à un support |
KR20120116401A (ko) | 2009-10-30 | 2012-10-22 | 얀센 파마슈티카 엔.브이. | 장기-작용성의 주사가능한 팔리페리돈 에스테르와 관련된 투약 요법 |
US9271939B2 (en) | 2010-03-15 | 2016-03-01 | Inventia Healthcare Private Limited | Stabilized prolonged release pharmaceutical composition comprising atypical antipsychotic |
EP2438930A1 (fr) | 2010-09-17 | 2012-04-11 | Sanofi-Aventis Deutschland GmbH | Promédicaments comprenant un conjugué de liaison d'exendine |
CN103249416B (zh) | 2010-10-18 | 2019-06-04 | 大日本住友制药株式会社 | 注射用缓释制剂 |
CN103561746B (zh) | 2011-03-18 | 2018-05-29 | 奥克梅斯制药爱尔兰有限公司 | 包含脱水山梨糖醇酯的药物组合物 |
WO2013046225A2 (fr) * | 2011-08-10 | 2013-04-04 | Glenmark Generics Limited | Procédé de préparation de palmitate de palipéridone |
CN102993200B (zh) * | 2011-09-10 | 2016-02-03 | 鲁翠涛 | 帕潘立酮氨基酸酯及其制备方法 |
EP2827868B8 (fr) | 2012-03-19 | 2019-12-18 | Alkermes Pharma Ireland Limited | Compositions pharmaceutiques comprenant des esters d'acides gras |
US9999670B2 (en) | 2012-03-19 | 2018-06-19 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising benzyl alcohol |
ES2764383T3 (es) | 2012-03-19 | 2020-06-03 | Alkermes Pharma Ireland Ltd | Composiciones farmacéuticas que comprenden ésteres de glicerol |
NZ748572A (en) | 2012-09-19 | 2020-07-31 | Alkermes Pharma Ireland Ltd | Pharmaceutical compositions having improved storage stability |
CA2891122C (fr) | 2012-11-14 | 2021-07-20 | The Johns Hopkins University | Methodes et compositions pour le traitement de la schizophrenie |
BR112015022587A2 (pt) | 2013-03-13 | 2017-10-24 | Eleven Biotherapeutics Inc | formulações de citocina quimérica para entrega ocular |
US11160785B2 (en) | 2013-03-15 | 2021-11-02 | Agenebio Inc. | Methods and compositions for improving cognitive function |
EP3827820A1 (fr) | 2013-03-15 | 2021-06-02 | The Johns Hopkins University | Brivaracetam pour améliorer la fonction cognitive |
GB2513172A (en) * | 2013-04-18 | 2014-10-22 | Nupharm Lab Ltd | Liquid dosage form and delivery system |
US10525057B2 (en) | 2013-09-24 | 2020-01-07 | Otsuka Pharmaceutical Co., Ltd. | Method of providing aripiprazole to patients having impaired CYP2D6 or CYP3A4 enzyme function |
CA2943213C (fr) | 2014-03-20 | 2022-07-05 | Alkermes Pharma Ireland Limited | Formulations d'aripiprazole presentant des vitesses d'injection plus elevees |
WO2016157061A1 (fr) | 2015-03-31 | 2016-10-06 | Wockhardt Limited | Procédé de broyage humide aseptique pour le palmitate de palipéridone |
EA037185B1 (ru) | 2015-04-07 | 2021-02-17 | Янссен Фармацевтика Н.В. | Способ лечения психоза, шизофрении или биполярного расстройства |
CN112843005B (zh) | 2015-05-22 | 2023-02-21 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
EP3700531A1 (fr) | 2017-10-27 | 2020-09-02 | Shandong Luye Pharmaceutical Co., Ltd. | Schéma posologique d'une suspension injectable à libération prolongée de palmitate de palipéridone |
EP3723760A4 (fr) * | 2017-12-14 | 2021-10-13 | SpecGx LLC | Procédé de broyage en une étape pour préparer des esters de palipéridone micronisés |
CA3092335A1 (fr) | 2018-03-05 | 2019-09-12 | Alkermes Pharma Ireland Limited | Strategie de dosage d'aripiprazole |
CN113024546B (zh) * | 2019-12-25 | 2022-06-10 | 江苏晶立信医药科技有限公司 | 一种小粒径棕榈酸帕利哌酮的制备方法 |
CA3203567A1 (fr) | 2020-11-30 | 2022-06-02 | Janssen Pharmaceutica Nv | Procedes destines a assurer la resuspension de formulations de palmitate de paliperidone |
US11324751B1 (en) | 2020-11-30 | 2022-05-10 | Janssen Pharmaceutica Nv | Dosing regimens associated with extended release paliperidone injectable formulations |
IL303252A (en) | 2020-11-30 | 2023-07-01 | Janssen Pharmaceutica Nv | Dosing regimens associated with delayed-release injectable formulations of paliperidone |
JP2023552329A (ja) | 2020-11-30 | 2023-12-15 | ヤンセン ファーマシューティカ エヌ.ベー. | 持続放出パリペリドン注射可能製剤に関連する投与レジメン |
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