FR2634397B2 - Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules - Google Patents

Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules

Info

Publication number
FR2634397B2
FR2634397B2 FR888808871A FR8808871A FR2634397B2 FR 2634397 B2 FR2634397 B2 FR 2634397B2 FR 888808871 A FR888808871 A FR 888808871A FR 8808871 A FR8808871 A FR 8808871A FR 2634397 B2 FR2634397 B2 FR 2634397B2
Authority
FR
France
Prior art keywords
nanoparticles
protein
preparation
colloidal systems
dispersible colloidal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR888808871A
Other languages
English (en)
Other versions
FR2634397A2 (fr
Inventor
Serge Stainmesse
Hatem Fessi
Jean-Philippe Devissaguet
Francis Puisieux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8618446A external-priority patent/FR2608988B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR888808871A priority Critical patent/FR2634397B2/fr
Priority to EP89401856A priority patent/EP0349428B1/fr
Priority to AT89401856T priority patent/ATE84710T1/de
Priority to ES89401856T priority patent/ES2054052T3/es
Priority to DE8989401856T priority patent/DE68904483T2/de
Priority to KR1019890009022A priority patent/KR960014870B1/ko
Priority to JP1169743A priority patent/JPH062224B2/ja
Priority to US07/374,246 priority patent/US5133908A/en
Publication of FR2634397A2 publication Critical patent/FR2634397A2/fr
Publication of FR2634397B2 publication Critical patent/FR2634397B2/fr
Application granted granted Critical
Priority to GR930400469T priority patent/GR3007248T3/el
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/12Powdering or granulating
    • C08J3/14Powdering or granulating by precipitation from solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/773Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/778Nanostructure within specified host or matrix material, e.g. nanocomposite films
    • Y10S977/786Fluidic host/matrix containing nanomaterials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/84Manufacture, treatment, or detection of nanostructure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR888808871A 1986-12-31 1988-06-30 Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules Expired - Lifetime FR2634397B2 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR888808871A FR2634397B2 (fr) 1986-12-31 1988-06-30 Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules
EP89401856A EP0349428B1 (fr) 1988-06-30 1989-06-28 Procédé de préparation de systèmes colloidaux dispersibles d'une protéine, sous forme de nanoparticules
AT89401856T ATE84710T1 (de) 1988-06-30 1989-06-28 Verfahren zur herstellung von kolloidalen dispergierbaren proteinsystemen, wie nanopartikeln.
ES89401856T ES2054052T3 (es) 1988-06-30 1989-06-28 Procedimiento de preparacion de sistemas coloidales dispersables de una proteina en forma de nanoparticulas.
DE8989401856T DE68904483T2 (de) 1988-06-30 1989-06-28 Verfahren zur herstellung von kolloidalen dispergierbaren proteinsystemen, wie nanopartikeln.
KR1019890009022A KR960014870B1 (ko) 1988-06-30 1989-06-29 나노 입자형 단백질의 분산성 교질상 시스템의 제조방법
JP1169743A JPH062224B2 (ja) 1988-06-30 1989-06-30 極小粒子形の蛋白質の分散性コロイド系の調製方法
US07/374,246 US5133908A (en) 1986-12-31 1989-06-30 Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles
GR930400469T GR3007248T3 (fr) 1988-06-30 1993-03-05

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8618446A FR2608988B1 (fr) 1986-12-31 1986-12-31 Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
FR888808871A FR2634397B2 (fr) 1986-12-31 1988-06-30 Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules

Publications (2)

Publication Number Publication Date
FR2634397A2 FR2634397A2 (fr) 1990-01-26
FR2634397B2 true FR2634397B2 (fr) 1991-04-19

Family

ID=26225686

Family Applications (1)

Application Number Title Priority Date Filing Date
FR888808871A Expired - Lifetime FR2634397B2 (fr) 1986-12-31 1988-06-30 Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules

Country Status (2)

Country Link
US (1) US5133908A (fr)
FR (1) FR2634397B2 (fr)

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FR2634397A2 (fr) 1990-01-26

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