FR2650182B1 - Procede de preparation d'une composition pharmaceutique sous forme de microparticules - Google Patents

Procede de preparation d'une composition pharmaceutique sous forme de microparticules

Info

Publication number
FR2650182B1
FR2650182B1 FR909009333A FR9009333A FR2650182B1 FR 2650182 B1 FR2650182 B1 FR 2650182B1 FR 909009333 A FR909009333 A FR 909009333A FR 9009333 A FR9009333 A FR 9009333A FR 2650182 B1 FR2650182 B1 FR 2650182B1
Authority
FR
France
Prior art keywords
microparticles
preparation
pharmaceutical composition
pharmaceutical
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR909009333A
Other languages
English (en)
Other versions
FR2650182A1 (fr
Inventor
Piero Orsolini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Debiopharm SA
Original Assignee
Debiopharm SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm SA filed Critical Debiopharm SA
Publication of FR2650182A1 publication Critical patent/FR2650182A1/fr
Application granted granted Critical
Publication of FR2650182B1 publication Critical patent/FR2650182B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF] (Somatoliberin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
FR909009333A 1989-07-28 1990-07-20 Procede de preparation d'une composition pharmaceutique sous forme de microparticules Expired - Lifetime FR2650182B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2829/89A CH679207A5 (fr) 1989-07-28 1989-07-28

Publications (2)

Publication Number Publication Date
FR2650182A1 FR2650182A1 (fr) 1991-02-01
FR2650182B1 true FR2650182B1 (fr) 1992-05-15

Family

ID=4242536

Family Applications (1)

Application Number Title Priority Date Filing Date
FR909009333A Expired - Lifetime FR2650182B1 (fr) 1989-07-28 1990-07-20 Procede de preparation d'une composition pharmaceutique sous forme de microparticules

Country Status (23)

Country Link
US (1) US5134122A (fr)
JP (1) JPH0662427B2 (fr)
AT (1) AT397197B (fr)
AU (1) AU619996B2 (fr)
BE (1) BE1003093A3 (fr)
CA (1) CA2021767C (fr)
CH (1) CH679207A5 (fr)
DE (1) DE4023134C2 (fr)
DK (1) DK175495B1 (fr)
ES (1) ES2020890A6 (fr)
FI (1) FI97688C (fr)
FR (1) FR2650182B1 (fr)
GB (1) GB2234169B (fr)
GR (1) GR1001215B (fr)
IE (1) IE65397B1 (fr)
IL (1) IL95120A (fr)
IT (1) IT1243357B (fr)
LU (1) LU87772A1 (fr)
NL (1) NL194858C (fr)
NO (1) NO300304B1 (fr)
PT (1) PT94842B (fr)
SE (1) SE504279C2 (fr)
ZA (1) ZA905654B (fr)

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WO1993015722A1 (fr) * 1992-02-07 1993-08-19 Syntex (Usa) Inc. Liberation controlee de produits pharmaceutiques a partir de microparticules poreuses preformees
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
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US5456917A (en) * 1993-04-12 1995-10-10 Cambridge Scientific, Inc. Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
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CA2178592C (fr) * 1993-12-09 2009-07-28 Jurgen Engel Suspensions pour injection a action prolongee et procede de preparation
US5417982A (en) * 1994-02-17 1995-05-23 Modi; Pankaj Controlled release of drugs or hormones in biodegradable polymer microspheres
US5569468A (en) * 1994-02-17 1996-10-29 Modi; Pankaj Vaccine delivery system for immunization, using biodegradable polymer microspheres
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Also Published As

Publication number Publication date
NL194858B (nl) 2003-01-06
GB2234169A (en) 1991-01-30
IE902592A1 (en) 1991-02-27
DK180790A (da) 1991-01-29
DE4023134A1 (de) 1991-01-31
NL9001646A (nl) 1991-02-18
ES2020890A6 (es) 1991-10-01
CA2021767C (fr) 1996-10-22
DE4023134C2 (de) 1997-04-17
FI97688B (fi) 1996-10-31
IT1243357B (it) 1994-06-10
IT9021019A0 (it) 1990-07-23
PT94842B (pt) 1997-04-30
LU87772A1 (fr) 1990-12-11
GB2234169B (en) 1993-02-10
GB9015722D0 (en) 1990-09-05
JPH0662427B2 (ja) 1994-08-17
NO903264L (no) 1991-01-29
BE1003093A3 (fr) 1991-11-19
NO300304B1 (no) 1997-05-12
FR2650182A1 (fr) 1991-02-01
FI97688C (fi) 1997-02-10
ATA154590A (de) 1993-07-15
GR900100568A (en) 1991-12-10
AT397197B (de) 1994-02-25
IT9021019A1 (it) 1992-01-23
AU5910390A (en) 1991-01-31
DK180790D0 (da) 1990-07-27
CH679207A5 (fr) 1992-01-15
NO903264D0 (no) 1990-07-23
AU619996B2 (en) 1992-02-06
GR1001215B (el) 1993-06-21
ZA905654B (en) 1991-05-29
IL95120A0 (en) 1991-06-10
FI903643A0 (fi) 1990-07-19
PT94842A (pt) 1991-03-20
SE9002522L (sv) 1991-01-29
NL194858C (nl) 2003-05-06
IL95120A (en) 1994-10-07
JPH0366625A (ja) 1991-03-22
SE504279C2 (sv) 1996-12-23
IE65397B1 (en) 1995-10-18
DK175495B1 (da) 2004-11-08
CA2021767A1 (fr) 1991-01-29
US5134122A (en) 1992-07-28
SE9002522D0 (sv) 1990-07-27

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