OA10478A - Nitro-benzamides useful as anti-arrhythmic agents - Google Patents

Nitro-benzamides useful as anti-arrhythmic agents Download PDF

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Publication number
OA10478A
OA10478A OA60996A OA60996A OA10478A OA 10478 A OA10478 A OA 10478A OA 60996 A OA60996 A OA 60996A OA 60996 A OA60996 A OA 60996A OA 10478 A OA10478 A OA 10478A
Authority
OA
OAPI
Prior art keywords
formula
compound
group
sait
pharmaceutically acceptable
Prior art date
Application number
OA60996A
Other languages
English (en)
Inventor
Guy Marguerite Marie Ge Nadler
Michel Jean Roger Martin
Original Assignee
Smithkline Beecham Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Lab filed Critical Smithkline Beecham Lab
Publication of OA10478A publication Critical patent/OA10478A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
OA60996A 1994-10-26 1997-04-25 Nitro-benzamides useful as anti-arrhythmic agents OA10478A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9412806A FR2726267B1 (fr) 1994-10-26 1994-10-26 Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer

Publications (1)

Publication Number Publication Date
OA10478A true OA10478A (en) 2002-04-09

Family

ID=9468229

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60996A OA10478A (en) 1994-10-26 1997-04-25 Nitro-benzamides useful as anti-arrhythmic agents

Country Status (36)

Country Link
US (3) US5977179A (es)
EP (1) EP0788474B1 (es)
JP (1) JPH10508013A (es)
KR (1) KR100369958B1 (es)
CN (1) CN1071740C (es)
AP (1) AP694A (es)
AT (1) ATE192428T1 (es)
AU (1) AU697357B2 (es)
BG (1) BG63367B1 (es)
BR (1) BR9509432A (es)
CA (1) CA2203814A1 (es)
CZ (1) CZ290326B6 (es)
DE (1) DE69516708T2 (es)
DK (1) DK0788474T3 (es)
DZ (1) DZ1937A1 (es)
ES (1) ES2145306T3 (es)
FI (1) FI971755A (es)
FR (1) FR2726267B1 (es)
GR (1) GR3033748T3 (es)
HK (1) HK1002764A1 (es)
HU (1) HU222889B1 (es)
ID (1) ID18094A (es)
IL (1) IL115732A (es)
MA (1) MA23706A1 (es)
NO (1) NO971955L (es)
NZ (1) NZ295368A (es)
OA (1) OA10478A (es)
PL (1) PL181936B1 (es)
PT (1) PT788474E (es)
RO (1) RO117174B1 (es)
RU (1) RU2159227C2 (es)
SK (1) SK281743B6 (es)
TR (1) TR199501320A2 (es)
UA (1) UA50722C2 (es)
WO (1) WO1996013479A1 (es)
ZA (1) ZA958984B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2726267B1 (fr) 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
GB9706376D0 (en) * 1997-03-27 1997-05-14 Smithkline Beecham Plc Novel pharmaceutical
GB9923934D0 (en) * 1999-10-08 1999-12-08 Smithkline Beecham Plc Novel pharmaceutical
GB9923933D0 (en) * 1999-10-08 1999-12-08 Smithkline Beecham Lab Novel pharmaceutical
ATE327230T1 (de) 2000-01-20 2006-06-15 Eisai Co Ltd Piperidinverbindungen und diese enthaltenden medikamente
AU2003282464B2 (en) * 2002-10-11 2010-02-25 Baxter International, Inc. Method for cardioprotection and neuroprotection by intravenous administration of halogenated volatile anesthetics
WO2004078715A1 (ja) 2003-03-07 2004-09-16 Astellas Pharma Inc. ２，６－ジ置換スチリルを有する含窒素へテロ環誘導体
RU2700263C1 (ru) * 2019-05-16 2019-09-16 федеральное государственное автономное образовательное учреждение высшего образования «Национальный исследовательский Томский политехнический университет» Средство, обладающее антиаритмическим действием

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE242344C (es)
US3139456A (en) * 1960-07-27 1964-06-30 Searle & Co Nu-(substituted phenoxyalkyl)-aralkylamines
DE3242344A1 (de) * 1982-11-16 1984-05-17 Dr. Karl Thomae Gmbh, 7950 Biberach Neue alkylendiaminoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
EG18188A (en) * 1986-05-01 1992-09-30 Pfizer Ltd Process for preparation anti-arhythmia agents
GB8706662D0 (en) * 1987-03-20 1987-04-23 Pfizer Ltd Anti-arrhythmia agents
CZ283038B6 (cs) * 1991-01-11 1997-12-17 Laboratoires Glaxo Sa Akridinové deriváty, způsob výroby a farmaceutické prostředky s jejich obsahem
US5208252A (en) * 1992-07-24 1993-05-04 Ortho Pharmaceutical Corporation Aminoethylthiophene derivatives
DE4422517A1 (de) * 1994-06-28 1996-01-04 Dresden Arzneimittel Neue (2-(3,4-Dimethoxy-phenyl)-ethyl)-(2-phenoxy-ethyl)-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
JP3904599B2 (ja) * 1994-08-04 2007-04-11 シー・アンド・シー・リサーチ・ラブズ 新規なアミン誘導体、その製造方法及び抗不整脈剤としての用途
FR2726267B1 (fr) 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer

Also Published As

Publication number Publication date
IL115732A (en) 2000-08-31
EP0788474B1 (en) 2000-05-03
KR100369958B1 (ko) 2003-04-08
FI971755A0 (fi) 1997-04-24
HUT77004A (hu) 1998-03-02
UA50722C2 (uk) 2002-11-15
RO117174B1 (ro) 2001-11-30
BR9509432A (pt) 1998-01-06
DE69516708T2 (de) 2000-09-28
GR3033748T3 (en) 2000-10-31
CA2203814A1 (en) 1996-05-09
US20010025054A1 (en) 2001-09-27
DE69516708D1 (de) 2000-06-08
AU697357B2 (en) 1998-10-01
MA23706A1 (fr) 1996-07-01
AU3869995A (en) 1996-05-23
FR2726267B1 (fr) 1998-01-02
ATE192428T1 (de) 2000-05-15
US6570037B2 (en) 2003-05-27
AP694A (en) 1998-11-18
SK50597A3 (en) 1997-11-05
EP0788474A1 (en) 1997-08-13
IL115732A0 (en) 1996-05-14
PT788474E (pt) 2000-08-31
NZ295368A (en) 1998-12-23
CZ125297A3 (en) 1997-10-15
HK1002764A1 (en) 1998-09-18
CN1071740C (zh) 2001-09-26
ZA958984B (en) 1997-04-24
ES2145306T3 (es) 2000-07-01
CN1170402A (zh) 1998-01-14
CZ290326B6 (cs) 2002-07-17
AP9700965A0 (en) 1997-04-30
DK0788474T3 (da) 2000-09-11
PL181936B1 (pl) 2001-10-31
RU2159227C2 (ru) 2000-11-20
HU222889B1 (hu) 2003-12-29
BG101501A (en) 1998-01-30
DZ1937A1 (fr) 2002-02-17
ID18094A (id) 1998-02-26
NO971955L (no) 1997-06-25
SK281743B6 (sk) 2001-07-10
MX9703112A (es) 1997-07-31
NO971955D0 (no) 1997-04-25
FR2726267A1 (fr) 1996-05-03
FI971755A (fi) 1997-06-23
PL319904A1 (en) 1997-09-01
BG63367B1 (bg) 2001-11-30
US20020107243A1 (en) 2002-08-08
WO1996013479A1 (en) 1996-05-09
JPH10508013A (ja) 1998-08-04
TR199501320A2 (tr) 1996-06-21
US5977179A (en) 1999-11-02

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