NZ542097A - 5,7-Diaminopyrazolo[4,3-d]pyrimidines useful in the treatment of hypertension - Google Patents

5,7-Diaminopyrazolo[4,3-d]pyrimidines useful in the treatment of hypertension

Info

Publication number
NZ542097A
NZ542097A NZ542097A NZ54209704A NZ542097A NZ 542097 A NZ542097 A NZ 542097A NZ 542097 A NZ542097 A NZ 542097A NZ 54209704 A NZ54209704 A NZ 54209704A NZ 542097 A NZ542097 A NZ 542097A
Authority
NZ
New Zealand
Prior art keywords
optionally substituted
compound according
compound
alkyl
ethyl
Prior art date
Application number
NZ542097A
Other languages
English (en)
Inventor
Andrew Simon Bell
David Graham Brown
David Nathan Abraham Fox
Ian Roger Marsh
Andrew Ian Morrell
Michael John Palmer
Carol Ann Winslow
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0327748.0A external-priority patent/GB0327748D0/en
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of NZ542097A publication Critical patent/NZ542097A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
NZ542097A 2003-04-29 2004-04-22 5,7-Diaminopyrazolo[4,3-d]pyrimidines useful in the treatment of hypertension NZ542097A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0309780 2003-04-29
GBGB0327748.0A GB0327748D0 (en) 2003-11-28 2003-11-28 Novel pharmaceuticals
PCT/IB2004/001433 WO2004096810A1 (en) 2003-04-29 2004-04-22 5,7-diaminopyrazolo`4,3-d!pyrimidines useful in the treatment of hypertension

Publications (1)

Publication Number Publication Date
NZ542097A true NZ542097A (en) 2008-12-24

Family

ID=33420887

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ542097A NZ542097A (en) 2003-04-29 2004-04-22 5,7-Diaminopyrazolo[4,3-d]pyrimidines useful in the treatment of hypertension

Country Status (31)

Country Link
US (2) US7262192B2 (enExample)
EP (1) EP1620437B1 (enExample)
JP (2) JP4015176B2 (enExample)
KR (1) KR100824193B1 (enExample)
AR (1) AR044116A1 (enExample)
AT (1) ATE433978T1 (enExample)
AU (1) AU2004234158B2 (enExample)
BR (1) BRPI0409903A (enExample)
CA (1) CA2523831C (enExample)
CL (1) CL2004000889A1 (enExample)
CO (1) CO5640118A2 (enExample)
CR (1) CR8051A (enExample)
DE (1) DE602004021585D1 (enExample)
DK (1) DK1620437T3 (enExample)
EA (1) EA008596B1 (enExample)
EC (1) ECSP056130A (enExample)
ES (1) ES2326119T3 (enExample)
GE (1) GEP20084329B (enExample)
IS (1) IS8009A (enExample)
MA (1) MA27771A1 (enExample)
MX (1) MXPA05011643A (enExample)
NL (1) NL1026074C2 (enExample)
NO (1) NO333850B1 (enExample)
NZ (1) NZ542097A (enExample)
OA (1) OA13050A (enExample)
PA (1) PA8601701A1 (enExample)
PE (1) PE20050462A1 (enExample)
RS (1) RS20050810A (enExample)
TW (1) TWI273908B (enExample)
UY (1) UY28290A1 (enExample)
WO (1) WO2004096810A1 (enExample)

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GB0327319D0 (en) 2003-11-24 2003-12-24 Pfizer Ltd Novel pharmaceuticals
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