NZ535381A - 5HT2c receptor modulators to treat obesity in a mammal - Google Patents

5HT2c receptor modulators to treat obesity in a mammal

Info

Publication number
NZ535381A
NZ535381A NZ535381A NZ53538103A NZ535381A NZ 535381 A NZ535381 A NZ 535381A NZ 535381 A NZ535381 A NZ 535381A NZ 53538103 A NZ53538103 A NZ 53538103A NZ 535381 A NZ535381 A NZ 535381A
Authority
NZ
New Zealand
Prior art keywords
benzazepine
tetrahydro
methyl
compound according
methoxy
Prior art date
Application number
NZ535381A
Other languages
English (en)
Inventor
Brian Smith
Jeffrey Smith
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29255581&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ535381(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of NZ535381A publication Critical patent/NZ535381A/en

Links

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • C—CHEMISTRY; METALLURGY
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    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
NZ535381A 2002-04-12 2003-04-11 5HT2c receptor modulators to treat obesity in a mammal NZ535381A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37205802P 2002-04-12 2002-04-12
US40549502P 2002-08-23 2002-08-23
US43460702P 2002-12-18 2002-12-18
US10/410,991 US6953787B2 (en) 2002-04-12 2003-04-10 5HT2C receptor modulators
PCT/US2003/011076 WO2003086306A2 (en) 2002-04-12 2003-04-11 5ht2c receptor modulators

Publications (1)

Publication Number Publication Date
NZ535381A true NZ535381A (en) 2006-07-28

Family

ID=29255581

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ535381A NZ535381A (en) 2002-04-12 2003-04-11 5HT2c receptor modulators to treat obesity in a mammal

Country Status (28)

Country Link
US (11) US6953787B2 (enExample)
EP (4) EP1557409A1 (enExample)
JP (5) JP4155926B2 (enExample)
KR (3) KR100908166B1 (enExample)
CN (5) CN100486967C (enExample)
AT (1) ATE294781T1 (enExample)
AU (1) AU2003221866B2 (enExample)
BR (2) BR122017023795B8 (enExample)
CA (1) CA2481723C (enExample)
CR (2) CR7503A (enExample)
DE (1) DE60300610T2 (enExample)
DK (1) DK1411881T3 (enExample)
ES (2) ES2242165T3 (enExample)
GE (1) GEP20074197B (enExample)
IL (1) IL164162A0 (enExample)
IS (1) IS2134B (enExample)
MX (1) MXPA04009965A (enExample)
MY (1) MY141476A (enExample)
NO (1) NO323528B1 (enExample)
NZ (1) NZ535381A (enExample)
PL (4) PL211314B1 (enExample)
PT (1) PT1411881E (enExample)
RU (1) RU2317982C2 (enExample)
SI (1) SI1411881T1 (enExample)
TW (1) TWI252105B (enExample)
UA (1) UA77788C2 (enExample)
WO (1) WO2003086306A2 (enExample)
ZA (1) ZA200408506B (enExample)

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US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
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PT1572215E (pt) 2002-12-20 2009-12-09 Glaxo Group Ltd Derivados de benzo[d]azepina para o tratamento de perturbações neurológicas
CN1805938B (zh) * 2003-06-17 2010-06-16 艾尼纳制药公司 用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
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WO2005042490A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
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RU2006117366A (ru) * 2003-10-23 2007-12-10 Ф.Хоффманн-Ля Рош Аг (Ch) Производные бензазепина в качестве ингибиторов мао-в
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JP4960235B2 (ja) * 2004-09-03 2012-06-27 アサーシス， インク． セロトニン受容体調節剤としての三環ヘテロアリールのピペラジン化合物、ピロリジン化合物およびアゼチジン化合物
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US20090203750A1 (en) * 2005-08-24 2009-08-13 Alan Kozikowski 5-HT2C Receptor Agonists as Anorectic Agents
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