NO996316L - Faktor Xa-inhibitorer med en noeytral P1-spesifisitetsgruppe - Google Patents
Faktor Xa-inhibitorer med en noeytral P1-spesifisitetsgruppeInfo
- Publication number
- NO996316L NO996316L NO996316A NO996316A NO996316L NO 996316 L NO996316 L NO 996316L NO 996316 A NO996316 A NO 996316A NO 996316 A NO996316 A NO 996316A NO 996316 L NO996316 L NO 996316L
- Authority
- NO
- Norway
- Prior art keywords
- inhibitors
- factor
- specificity group
- neutral
- somewhat neutral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87888597A | 1997-06-19 | 1997-06-19 | |
| US7669198P | 1998-02-27 | 1998-02-27 | |
| PCT/US1998/012681 WO1998057937A2 (en) | 1997-06-19 | 1998-06-18 | Inhibitors of factor xa with a neutral p1 specificity group |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO996316L true NO996316L (no) | 1999-12-17 |
| NO996316D0 NO996316D0 (no) | 1999-12-17 |
Family
ID=26758382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO996316A NO996316D0 (no) | 1997-06-19 | 1999-12-17 | Faktor Xa-inhibitorer med en noeytral P1-spesifisitetsgruppe |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0991625B1 (de) |
| JP (1) | JP2002507968A (de) |
| KR (1) | KR20010013977A (de) |
| AR (1) | AR015906A1 (de) |
| AT (1) | ATE296805T1 (de) |
| AU (1) | AU8150398A (de) |
| BR (1) | BR9810151A (de) |
| CA (1) | CA2290982A1 (de) |
| DE (1) | DE69830403T2 (de) |
| EA (1) | EA200000048A1 (de) |
| EE (1) | EE9900584A (de) |
| ES (1) | ES2239806T3 (de) |
| HR (1) | HRP980334A2 (de) |
| HU (1) | HUP0003906A2 (de) |
| IL (1) | IL133526A0 (de) |
| LV (1) | LV12516B (de) |
| NO (1) | NO996316D0 (de) |
| PL (1) | PL337831A1 (de) |
| PT (1) | PT991625E (de) |
| SI (1) | SI20208A (de) |
| SK (1) | SK174699A3 (de) |
| WO (1) | WO1998057937A2 (de) |
Families Citing this family (104)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1012150A4 (de) * | 1997-05-19 | 2002-05-29 | Sugen Inc | Heteroarylcarboxamid-verbindungen die gegen durch protein-tyrosin-kinase verursachte krankheiten wirksam sind |
| US6271237B1 (en) | 1997-12-22 | 2001-08-07 | Dupont Pharmaceuticals Company | Nitrogen containing heteromatics with ortho-substituted P1s as factor Xa inhabitors |
| EP1042299A1 (de) * | 1997-12-22 | 2000-10-11 | Du Pont Pharmaceuticals Company | Stickstoffenthaltende heteroaromaten mit ortho-substituierten p1 gruppen als faktor-xa-inhibitoren |
| US6358960B1 (en) | 1998-02-17 | 2002-03-19 | Ono Pharmaceutical Co., Ltd. | Amidino derivatives and drugs containing the same as the active ingredient |
| WO1999050255A2 (en) * | 1998-03-27 | 1999-10-07 | Du Pont Pharmaceuticals Company | Disubstituted pyrazolines and triazolines as factor xa inhibitors |
| EP1101759A4 (de) | 1998-07-31 | 2001-12-12 | Nippon Soda Co | Phenylazol-derivate, verfahren zu ihrer herstellung und medikamente für hyperlipemie |
| CA2320730A1 (en) * | 1998-12-23 | 2000-07-06 | Renhua Li | Thrombin or factor xa inhibitors |
| CA2360740A1 (en) | 1999-03-02 | 2000-09-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compounds useful as reversible inhibitors of cathepsin s |
| DE60003025T2 (de) | 1999-04-02 | 2004-03-18 | Bristol-Myers Squibb Pharma Co. | Arylsulfonyle als faktor xa inhibitoren |
| US7125875B2 (en) | 1999-04-15 | 2006-10-24 | Bristol-Myers Squibb Company | Cyclic protein tyrosine kinase inhibitors |
| BR0009721A (pt) * | 1999-04-15 | 2002-02-13 | Bristol Myers Squibb Co | Inibidores de tirosina quinase de proteìna cìclica |
| DE60011430T2 (de) | 1999-07-16 | 2005-07-07 | Bristol-Myers Squibb Pharma Co. | Stickstoff enthaltende heterobicyclen als factor xa inhibitoren |
| US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
| WO2001032628A1 (en) * | 1999-11-03 | 2001-05-10 | Bristol-Myers Squibb Pharma Company | Cyano compounds as factor xa inhibitors |
| US6407256B1 (en) | 1999-11-03 | 2002-06-18 | Bristol Myers Squibb Co | Cyano-pyrrole, cyano-imidazole, cyano-pyrazole, and cyano-triazole compounds as factor Xa inhibitors |
| MY138097A (en) | 2000-03-22 | 2009-04-30 | Du Pont | Insecticidal anthranilamides |
| AU2001268712A1 (en) | 2000-06-23 | 2002-01-08 | Bristol-Myers Squibb Company | 1 - (heteroaryl-phenyl) - condensed pyrazol derivatives as factor Xa inhibitors |
| JP2004501913A (ja) | 2000-06-23 | 2004-01-22 | ブリストル−マイヤーズ スクイブ ファーマ カンパニー | ヘテロアリール−フェニル置換Ｘａ因子阻害剤 |
| WO2002002519A2 (en) * | 2000-06-29 | 2002-01-10 | Bristol-Myers Squibb Pharma Company | THROMBIN OR FACTOR Xa INHIBITORS |
| WO2002037937A2 (en) | 2000-11-07 | 2002-05-16 | Bristol-Myers Squibb Company | Acid derivatives useful as serine protease inhibitors |
| US6642252B2 (en) | 2000-11-07 | 2003-11-04 | Bristol-Myers Squibb Company | Acid derivatives useful as serine protease inhibitors |
| US6906192B2 (en) | 2000-11-07 | 2005-06-14 | Bristol Myers Squibb Company | Processes for the preparation of acid derivatives useful as serine protease inhibitors |
| TWI312274B (en) | 2001-08-13 | 2009-07-21 | Du Pont | Method for controlling particular insect pests by applying anthranilamide compounds |
| AR036872A1 (es) | 2001-08-13 | 2004-10-13 | Du Pont | Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados |
| EP1417204B1 (de) | 2001-08-15 | 2006-01-18 | E. I. du Pont de Nemours and Company | Mit heterocyclen ortho-substituierte aryl amide zur bekämpfung wirbelloser schädlinge |
| AU2002331706B2 (en) | 2001-08-15 | 2009-01-22 | E.I. Du Pont De Nemours And Company | Ortho-substituted aryl amides for controlling invertebrate pests |
| EP1417176B1 (de) | 2001-08-16 | 2008-12-17 | E.I. Du Pont De Nemours And Company | Substituierte anthranilamide und ihre verwendung als pesticide |
| TWI331526B (en) | 2001-09-21 | 2010-10-11 | Bristol Myers Squibb Pharma Co | Lactam-containing compounds and derivatives thereof as factor xa inhibitors |
| CA2726702A1 (en) | 2001-09-21 | 2003-04-03 | Bristol-Myers Squibb Company | Lactam-containing compounds and derivatives thereof as factor xa inhibitors |
| TWI283164B (en) | 2001-09-21 | 2007-07-01 | Du Pont | Anthranilamide arthropodicide treatment |
| EP1443930A1 (de) | 2001-10-25 | 2004-08-11 | AstraZeneca AB | Isoxazolinderivative verwendbar als antimikrobielle agenzien |
| WO2003062226A1 (en) | 2002-01-22 | 2003-07-31 | E. I. Du Pont De Nemours And Company | Quinazoline(di) ones for invertebrate pest control |
| AU2003273179A1 (en) | 2002-05-10 | 2003-12-12 | Bristol-Myers Squibb Company | 1,1-disubstituted cycloalkyl derivatives as factor xa inhibitors |
| KR20050009747A (ko) | 2002-06-13 | 2005-01-25 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 피라졸카르복사미드 살충제 |
| DE10229070A1 (de) * | 2002-06-28 | 2004-01-15 | Merck Patent Gmbh | Phenylderivate 5 |
| JP4648705B2 (ja) | 2002-11-15 | 2011-03-09 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 新規アントラニルアミド殺虫剤 |
| DK1569912T3 (en) | 2002-12-03 | 2015-06-29 | Pharmacyclics Inc | 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors. |
| US7071355B2 (en) | 2002-12-23 | 2006-07-04 | 4 Sc Ag | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
| US7247736B2 (en) | 2002-12-23 | 2007-07-24 | 4Sc Ag | Method of identifying inhibitors of DHODH |
| EP1581477B1 (de) * | 2002-12-23 | 2009-12-02 | 4Sc Ag | Cycloalken-dicarbonsäure-verbindungen als entzündungshemmende, immunmodulatorische und antiproliferative mittel |
| US7365094B2 (en) | 2002-12-23 | 2008-04-29 | 4Sc Ag | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
| PL209772B1 (pl) | 2003-01-28 | 2011-10-31 | Du Pont | Antraniloamidy, środek do zwalczania szkodnika będącego bezkręgowcem i sposób zwalczania szkodnika będącego bezkręgowcem |
| US7122557B2 (en) | 2003-03-18 | 2006-10-17 | Bristol-Myers Squibb Company | Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors |
| US20040220170A1 (en) * | 2003-05-01 | 2004-11-04 | Atkinson Robert N. | Pyrazole-amides and sulfonamides as sodium channel modulators |
| CA2525325A1 (en) * | 2003-05-01 | 2004-11-18 | Abbott Laboratories | Pyrazole-amides and sulfonamides as sodium channel modulators |
| PL2256106T3 (pl) | 2003-07-22 | 2015-08-31 | Astex Therapeutics Ltd | Związki 3,4-pochodne 1h-pirazolu i ich zastosowanie jako kinazy zależne od cyklin (cdk) i modulatory kinazy syntazy glikogenu-3 (gsk-3) |
| CA2533594C (en) * | 2003-07-23 | 2013-04-02 | Synta Pharmaceuticals, Corp. | Compounds for inflammation and immune-related uses |
| EP3002283B1 (de) | 2003-12-26 | 2017-06-14 | Kyowa Hakko Kirin Co., Ltd. | Thiazol-derivate |
| ES2526614T3 (es) | 2004-03-05 | 2015-01-13 | Nissan Chemical Industries, Ltd. | Compuesto de benzamida sustituida con isoxazolina y agente de control de organismos nocivos |
| AU2005223483B2 (en) | 2004-03-18 | 2009-04-23 | Zoetis Llc | N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides |
| GT200500179AA (es) | 2004-07-01 | 2008-10-29 | Mezclas sinergistas de agentes de antranilamida para el control de plagas de invertebrados | |
| JP2008512364A (ja) * | 2004-09-06 | 2008-04-24 | エフ．ホフマン−ラ ロシュ アーゲー | ４−アミノメチルベンズアミジン誘導体及び第ＶＩＩａ因子阻害剤としてのその使用 |
| KR20070107022A (ko) | 2005-01-07 | 2007-11-06 | 신타 파마슈티칼스 코프. | 염증 및 면역 관련 용도를 위한 화합물 |
| US8404718B2 (en) | 2005-01-21 | 2013-03-26 | Astex Therapeutics Limited | Combinations of pyrazole kinase inhibitors |
| AR054425A1 (es) | 2005-01-21 | 2007-06-27 | Astex Therapeutics Ltd | Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico. |
| US20100280023A1 (en) | 2005-06-23 | 2010-11-04 | Kyowa Hakko Kogyo Co., Ltd. | Thiazole derivatives |
| BRPI0613045A2 (pt) * | 2005-07-15 | 2010-12-14 | Hoffmann La Roche | aminas cÍclicas fundidas a heteroarila |
| EP1924575A1 (de) | 2005-08-24 | 2008-05-28 | E.I.Du pont de nemours and company | Anthranilamide zur kontrolle von wirbellosen schädlingen |
| TWI324908B (en) | 2006-01-05 | 2010-05-21 | Du Pont | Liquid formulations of carboxamide arthropodicides |
| CN101379049B (zh) * | 2006-01-31 | 2012-01-04 | 同和药品株式会社 | 新型的苄脒衍生物，它的制备方法，和包含该衍生物的药物组合物 |
| CA2658523C (en) * | 2006-07-31 | 2012-06-12 | Activesite Pharmaceuticals, Inc. | Inhibitors of plasma kallikrein |
| EP1894928A1 (de) | 2006-08-29 | 2008-03-05 | PheneX Pharmaceuticals AG | Fxr bindende heterocyclische verbindungen |
| WO2008059335A1 (en) | 2006-11-13 | 2008-05-22 | Pfizer Products Inc. | Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof |
| AR072297A1 (es) | 2008-06-27 | 2010-08-18 | Novartis Ag | Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona. |
| AU2009316786A1 (en) * | 2008-11-19 | 2010-05-27 | Merck Sharp & Dohme Corp. | Inhibitors of diacylglycerol acyltransferase |
| MX2012006723A (es) | 2009-12-15 | 2012-06-28 | Bayer Cropscience Ag | Procedimiento para la preparacion de derivados de acido 1-alquil-/1-aril-5-pirazolcarboxilico. |
| US8609866B2 (en) | 2009-12-18 | 2013-12-17 | Activesite Pharmaceuticals, Inc. | Prodrugs of inhibitors of plasma kallikrein |
| NZ610331A (en) * | 2010-10-20 | 2015-01-30 | Biota Scient Management | Viral polymerase inhibitors |
| KR101373185B1 (ko) * | 2010-12-17 | 2014-03-13 | 주식회사경농 | 인다졸 유도체 및 이를 함유하는 살충제 조성물 |
| JP5968999B2 (ja) | 2011-03-31 | 2016-08-10 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | 除草剤としておよび殺菌剤として活性な３−フェニルイソオキサゾリン−５−カルボキサミドおよび３−フェニルイソオキサゾリン−５−チオアミド |
| EP2697196A1 (de) | 2011-04-13 | 2014-02-19 | Activesite Pharmaceuticals, Inc. | Prodrugs von plasmakallikreinhemmern |
| US9199975B2 (en) | 2011-09-30 | 2015-12-01 | Asana Biosciences, Llc | Biaryl imidazole derivatives for regulating CYP17 |
| BR112014007694B1 (pt) | 2011-10-03 | 2022-09-27 | Respivert Limited | Compostos de 1-(3-(tert-butil)-1-(p-tolil)-1h-pirazol-5-il)-3-(4-((2-(fenilamino) pirimidin-4-il)óxi) naftalen-1-il)ureia, seus usos, composição e formulação farmacêutica compreendendo os mesmos |
| EP2578582A1 (de) | 2011-10-03 | 2013-04-10 | Respivert Limited | 1-Pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl) Harnstoffe als p38 MAP Kinasehemmer |
| KR102040740B1 (ko) * | 2012-09-25 | 2019-11-05 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 제초 및 살진균성 5-옥시-치환된 3-페닐이속사졸린-5-카복사미드 및 5-옥시-치환된 3-페닐이속사졸린-5-티오아미드 |
| CN108477173B (zh) | 2012-10-02 | 2021-07-02 | 拜耳农作物科学股份公司 | 作为杀虫剂的杂环化合物 |
| TW201444798A (zh) | 2013-02-28 | 2014-12-01 | 必治妥美雅史谷比公司 | 作爲強效ｒｏｃｋ１及ｒｏｃｋ２抑制劑之苯基吡唑衍生物 |
| EP2961746B1 (de) | 2013-02-28 | 2018-01-03 | Bristol-Myers Squibb Company | Phenylpyrazolderivate als potente rock1- und rock2-inhibitoren |
| SG11201607267SA (en) | 2014-03-07 | 2016-09-29 | Biocryst Pharm Inc | Human plasma kallikrein inhibitors |
| CN104086492B (zh) * | 2014-07-23 | 2015-12-30 | 张远强 | 抗血栓化合物、其制备方法和用途 |
| CN104072431B (zh) * | 2014-07-23 | 2015-11-18 | 张远强 | 烷氧基取代的苯基三唑希夫碱结构的化合物及用途 |
| CN104086497B (zh) * | 2014-07-23 | 2016-03-02 | 张远强 | 三唑希夫碱类化合物、其制备方法和用途 |
| CN104072434B (zh) * | 2014-07-23 | 2015-12-02 | 张远强 | 间位取代的四氮唑苯乙酮化合物、其制备方法和用途 |
| CN104072435B (zh) * | 2014-07-23 | 2015-11-04 | 张远强 | 双烷基取代的四氮唑苯乙酮化合物和用途 |
| CN104072437B (zh) * | 2014-07-23 | 2015-10-14 | 张远强 | 双取代的四氮唑苯乙酮化合物、其制备方法和用途 |
| CN104072436B (zh) * | 2014-07-23 | 2015-10-14 | 张远强 | 对位取代的四氮唑苯乙酮化合物、其制备方法和用途 |
| CN104086502B (zh) * | 2014-07-23 | 2015-10-14 | 张远强 | 卤代四氮唑苯乙酮化合物、其制备方法和用途 |
| CN104072439B (zh) * | 2014-07-23 | 2015-11-04 | 张远强 | 卤素取代的四氮唑苯乙酮化合物、其制备方法和用途 |
| CN104072432B (zh) * | 2014-07-23 | 2015-12-30 | 张远强 | 含苯基取代三唑希夫碱类结构的化合物、其制备方法和用途 |
| CN104086503B (zh) * | 2014-07-23 | 2015-10-14 | 张远强 | Par-1拮抗剂及其用途 |
| CN104072438B (zh) * | 2014-07-23 | 2015-10-14 | 张远强 | 二烷氧代四氮唑苯乙酮化合物、其制备方法和用途 |
| CN104086501B (zh) * | 2014-07-23 | 2016-02-17 | 张远强 | 一种par-1拮抗剂、其制备方法和用途 |
| CN104086498B (zh) * | 2014-07-23 | 2015-11-18 | 张远强 | 末端取代的三唑希夫碱类结构的化合物、其制备方法和用途 |
| CN104086500B (zh) * | 2014-07-23 | 2015-08-26 | 张远强 | 一种par-1拮抗剂及其用途 |
| CN104086493B (zh) * | 2014-07-23 | 2016-05-18 | 张远强 | 末端取代的苯基三唑希夫碱结构的化合物及其用途 |
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| BR112020003266A2 (pt) | 2017-08-17 | 2020-10-13 | Bayer Aktiengesellschaft | 3-fenil-5-trifluorometilisoxazolina-5-carboxamidas herbicidamente ativas de ésteres e ácidos ciclopentilcarboxílicos |
| US20220306591A1 (en) | 2018-01-25 | 2022-09-29 | Bayer Aktiengesellschaft | Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentenylcarboxylic acid derivatives |
| EP3937637B1 (de) | 2019-03-12 | 2023-04-19 | Bayer Aktiengesellschaft | Herbizid wirksame 3-phenylisoxazolin-5-carboxamide von s-haltigen cyclopentenylcarbonsäureestern |
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| HUT74690A (en) * | 1993-11-24 | 1997-01-28 | Du Pont Merck Pharma | Novel isoxazoline and isoxazole fibrinogen receptor antagonists process for producing them and pharmaceutical compositions containing them |
| US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
| US5563158A (en) * | 1993-12-28 | 1996-10-08 | The Dupont Merck Pharmaceutical Company | Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists |
| DE4405207A1 (de) * | 1994-02-18 | 1995-08-24 | Bayer Ag | N-Pyrazolylaniline und N-Pyrazolylaminopyridine |
| CA2214685C (en) * | 1995-03-10 | 2008-05-20 | Berlex Laboratories, Inc. | Benzamidine derivatives their preparation and their use as anti-coagulants |
| IL118007A0 (en) | 1995-05-24 | 1996-08-04 | Du Pont Merck Pharma | Isoxazoline compounds pharmaceutical compositions containing them and their use |
-
1998
- 1998-06-18 KR KR19997012003A patent/KR20010013977A/ko not_active Application Discontinuation
- 1998-06-18 AT AT98931355T patent/ATE296805T1/de not_active IP Right Cessation
- 1998-06-18 SI SI9820043A patent/SI20208A/sl not_active IP Right Cessation
- 1998-06-18 SK SK1746-99A patent/SK174699A3/sk unknown
- 1998-06-18 IL IL13352698A patent/IL133526A0/xx unknown
- 1998-06-18 EA EA200000048A patent/EA200000048A1/ru unknown
- 1998-06-18 AU AU81503/98A patent/AU8150398A/en not_active Abandoned
- 1998-06-18 BR BR9810151-0A patent/BR9810151A/pt not_active IP Right Cessation
- 1998-06-18 EE EEP199900584A patent/EE9900584A/xx unknown
- 1998-06-18 ES ES98931355T patent/ES2239806T3/es not_active Expired - Lifetime
- 1998-06-18 HU HU0003906A patent/HUP0003906A2/hu unknown
- 1998-06-18 DE DE69830403T patent/DE69830403T2/de not_active Expired - Lifetime
- 1998-06-18 PL PL98337831A patent/PL337831A1/xx not_active Application Discontinuation
- 1998-06-18 CA CA002290982A patent/CA2290982A1/en not_active Abandoned
- 1998-06-18 WO PCT/US1998/012681 patent/WO1998057937A2/en active IP Right Grant
- 1998-06-18 PT PT98931355T patent/PT991625E/pt unknown
- 1998-06-18 EP EP98931355A patent/EP0991625B1/de not_active Revoked
- 1998-06-18 JP JP50478699A patent/JP2002507968A/ja active Pending
- 1998-06-18 HR HR60/076,691A patent/HRP980334A2/hr not_active Application Discontinuation
- 1998-06-19 AR ARP980102939A patent/AR015906A1/es unknown
-
1999
- 1999-12-16 LV LVP-99-177A patent/LV12516B/en unknown
- 1999-12-17 NO NO996316A patent/NO996316D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002507968A (ja) | 2002-03-12 |
| WO1998057937A2 (en) | 1998-12-23 |
| SK174699A3 (en) | 2000-08-14 |
| LV12516B (en) | 2001-03-20 |
| AU8150398A (en) | 1999-01-04 |
| EA200000048A1 (ru) | 2000-08-28 |
| DE69830403D1 (de) | 2005-07-07 |
| EE9900584A (et) | 2000-08-15 |
| EP0991625B1 (de) | 2005-06-01 |
| AR015906A1 (es) | 2001-05-30 |
| KR20010013977A (ko) | 2001-02-26 |
| PT991625E (pt) | 2005-10-31 |
| PL337831A1 (en) | 2000-09-11 |
| IL133526A0 (en) | 2001-04-30 |
| ATE296805T1 (de) | 2005-06-15 |
| ES2239806T3 (es) | 2005-10-01 |
| HUP0003906A2 (hu) | 2001-05-28 |
| LV12516A (en) | 2000-07-20 |
| HRP980334A2 (en) | 1999-04-30 |
| SI20208A (sl) | 2000-10-31 |
| DE69830403T2 (de) | 2006-02-02 |
| WO1998057937A3 (en) | 1999-03-18 |
| NO996316D0 (no) | 1999-12-17 |
| CA2290982A1 (en) | 1998-12-23 |
| EP0991625A2 (de) | 2000-04-12 |
| BR9810151A (pt) | 2000-08-08 |
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