CN104086497B - 三唑希夫碱类化合物、其制备方法和用途 - Google Patents
三唑希夫碱类化合物、其制备方法和用途 Download PDFInfo
- Publication number
- CN104086497B CN104086497B CN201410352080.7A CN201410352080A CN104086497B CN 104086497 B CN104086497 B CN 104086497B CN 201410352080 A CN201410352080 A CN 201410352080A CN 104086497 B CN104086497 B CN 104086497B
- Authority
- CN
- China
- Prior art keywords
- compound
- general formula
- preparation
- defines
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 0 CC(C)N(C(SCC(C(C1)=CC(N2CCOCC2)=C(*)C1C(C)(C)C)=O)=NN)N=Cc1ccccc1 Chemical compound CC(C)N(C(SCC(C(C1)=CC(N2CCOCC2)=C(*)C1C(C)(C)C)=O)=NN)N=Cc1ccccc1 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410352080.7A CN104086497B (zh) | 2014-07-23 | 2014-07-23 | 三唑希夫碱类化合物、其制备方法和用途 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410352080.7A CN104086497B (zh) | 2014-07-23 | 2014-07-23 | 三唑希夫碱类化合物、其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104086497A CN104086497A (zh) | 2014-10-08 |
CN104086497B true CN104086497B (zh) | 2016-03-02 |
Family
ID=51634287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410352080.7A Active CN104086497B (zh) | 2014-07-23 | 2014-07-23 | 三唑希夫碱类化合物、其制备方法和用途 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104086497B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104529928A (zh) * | 2015-01-13 | 2015-04-22 | 佛山市赛维斯医药科技有限公司 | 一类恶二唑亚砜化合物、其制备方法和用途 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102442965A (zh) * | 2010-09-30 | 2012-05-09 | 天津药物研究院 | 用于治疗血栓性疾病的par-1拮抗剂及其制备方法和用途 |
CN103613553A (zh) * | 2013-12-09 | 2014-03-05 | 兴义民族师范学院 | 均三唑席夫碱双酰胺衍生物及制备方法和用途 |
CN103739594A (zh) * | 2012-10-17 | 2014-04-23 | 南京大学 | 一类含吡嗪环和三氮唑结构的席夫碱类衍生物及其制法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9810151A (pt) * | 1997-06-19 | 2000-08-08 | Du Pont Pharm Co | Composto, composição farmacêutica e método para tratamento ou prevenção de uma desordem tromoboembólica |
-
2014
- 2014-07-23 CN CN201410352080.7A patent/CN104086497B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102442965A (zh) * | 2010-09-30 | 2012-05-09 | 天津药物研究院 | 用于治疗血栓性疾病的par-1拮抗剂及其制备方法和用途 |
CN103739594A (zh) * | 2012-10-17 | 2014-04-23 | 南京大学 | 一类含吡嗪环和三氮唑结构的席夫碱类衍生物及其制法 |
CN103613553A (zh) * | 2013-12-09 | 2014-03-05 | 兴义民族师范学院 | 均三唑席夫碱双酰胺衍生物及制备方法和用途 |
Non-Patent Citations (4)
Title |
---|
3-甲基-4-氨基-5-乙氧羰基甲硫基三唑席夫碱的合成及生物活性;杨清翠,等.;《化学通报》;20131231;第76卷(第8期);758-761 * |
Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(Ⅱ), Ni(Ⅱ) and Cu(Ⅱ) complexes with 1,2,4-triazole Schiff bases;Gangadhar B. Bagihalli,et al.;《European Journal of Medicinal Chemistry》;20081231;第43卷;2639-2649 * |
Thrombin Receptor(Protease Activated Receptor-1) Antagonists as Potent Antithrombotic Agents with Strong Antiplatelet Effects;Samuel Chackalamannil;《Journal of Medicinal Chemistry》;20060907;第49卷(第18期);5389-5403 * |
三唑类席夫碱衍生物的研究新进展;陶燕,等.;《应用化工》;20090531;第38卷(第5期);721-723,728 * |
Also Published As
Publication number | Publication date |
---|---|
CN104086497A (zh) | 2014-10-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104072434B (zh) | 间位取代的四氮唑苯乙酮化合物、其制备方法和用途 | |
CN104072436B (zh) | 对位取代的四氮唑苯乙酮化合物、其制备方法和用途 | |
CN104098520B (zh) | 苯基三唑希夫碱类化合物、其制备方法和用途 | |
CN104529927B (zh) | 一类含卤代苯的恶二唑亚砜化合物、其制备方法和用途 | |
CN104086503B (zh) | Par-1拮抗剂及其用途 | |
CN104072438B (zh) | 二烷氧代四氮唑苯乙酮化合物、其制备方法和用途 | |
CN104072437B (zh) | 双取代的四氮唑苯乙酮化合物、其制备方法和用途 | |
CN104072439B (zh) | 卤素取代的四氮唑苯乙酮化合物、其制备方法和用途 | |
CN104086500B (zh) | 一种par-1拮抗剂及其用途 | |
CN104086497B (zh) | 三唑希夫碱类化合物、其制备方法和用途 | |
CN104072432B (zh) | 含苯基取代三唑希夫碱类结构的化合物、其制备方法和用途 | |
CN104086498B (zh) | 末端取代的三唑希夫碱类结构的化合物、其制备方法和用途 | |
CN104072431B (zh) | 烷氧基取代的苯基三唑希夫碱结构的化合物及用途 | |
CN104086494B (zh) | 末端双取代的甲基三唑希夫碱结构化合物、其制备方法和用途 | |
CN104086495B (zh) | 末端双取代的三唑希夫碱结构化合物、其制备方法和用途 | |
CN104140398B (zh) | 甲基三唑希夫碱类结构的化合物、其制备方法和用途 | |
CN104086502B (zh) | 卤代四氮唑苯乙酮化合物、其制备方法和用途 | |
CN104072435B (zh) | 双烷基取代的四氮唑苯乙酮化合物和用途 | |
CN104086496B (zh) | 一种抗血栓化合物、其制备方法和用途 | |
CN104529931B (zh) | 一类含烷氧对位取代苯的恶二唑亚砜化合物、其制备方法和用途 | |
CN104513212B (zh) | 一类含硝基苯的恶二唑亚砜化合物、其制备方法和用途 | |
CN104529929B (zh) | 含烷氧取代苯的恶二唑亚砜化合物、其制备方法和用途 | |
CN104529930B (zh) | 一类含腈基苯的噁二唑亚砜化合物、其制备方法和用途 | |
CN104496925B (zh) | 二烯四氮唑类化合物、其制备方法和用途 | |
CN104086493A (zh) | 末端取代的苯基三唑希夫碱结构的化合物及其用途 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20180925 Address after: 226499 No. twelve, group twelve, Hong Yuan village, dugong Town, Rudong County, Jiangsu Patentee after: Xi Jinming Address before: 528000 floor 5, Pu Lan Road, Chancheng District, Foshan, Guangdong. Patentee before: Zhang Yuanqiang |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20200316 Address after: 233000 Huahai Jinxiu facade, 3rd road, Guzhen County, Bengbu City, Anhui Province 2 uff03 105 Patentee after: Bengbu Geshi Intellectual Property Operations Co., Ltd. Address before: 226499 No. twelve, No. 20, rainbow Yuan village, dug Town, Jiangsu County, Rudong Patentee before: Xi Jinming |
|
TR01 | Transfer of patent right |