NO984588L - FremgangsmÕte for fremstilling av 2,5-di-amino-4,6-diklorpyrimidin - Google Patents

FremgangsmÕte for fremstilling av 2,5-di-amino-4,6-diklorpyrimidin

Info

Publication number
NO984588L
NO984588L NO984588A NO984588A NO984588L NO 984588 L NO984588 L NO 984588L NO 984588 A NO984588 A NO 984588A NO 984588 A NO984588 A NO 984588A NO 984588 L NO984588 L NO 984588L
Authority
NO
Norway
Prior art keywords
formula
alkyl
dichloropyrimidine
amino
diamino
Prior art date
Application number
NO984588A
Other languages
English (en)
Other versions
NO984588D0 (no
NO306859B1 (no
Inventor
Gerhard Stucky
Renu Imwinkelried
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4207186&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO984588(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of NO984588L publication Critical patent/NO984588L/no
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of NO984588D0 publication Critical patent/NO984588D0/no
Publication of NO306859B1 publication Critical patent/NO306859B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO984588A 1994-04-27 1998-10-01 Fremgangsmåte for fremstilling av 2,5-di-amino-4,6-diklorpyrimidin NO306859B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH129994 1994-04-27

Publications (3)

Publication Number Publication Date
NO984588L true NO984588L (no) 1995-10-30
NO984588D0 NO984588D0 (no) 1998-10-01
NO306859B1 NO306859B1 (no) 2000-01-03

Family

ID=4207186

Family Applications (2)

Application Number Title Priority Date Filing Date
NO951594A NO306461B1 (no) 1994-04-27 1995-04-26 N-(2-amino-4,6-diklorpyrimidin-5-yl) formamid samt fremgangsmÕte ved fremstilling derav
NO984588A NO306859B1 (no) 1994-04-27 1998-10-01 Fremgangsmåte for fremstilling av 2,5-di-amino-4,6-diklorpyrimidin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO951594A NO306461B1 (no) 1994-04-27 1995-04-26 N-(2-amino-4,6-diklorpyrimidin-5-yl) formamid samt fremgangsmÕte ved fremstilling derav

Country Status (18)

Country Link
US (4) US5583226A (no)
EP (2) EP0816344B1 (no)
JP (2) JP3811966B2 (no)
KR (1) KR100327996B1 (no)
CN (2) CN1065862C (no)
AT (2) ATE167672T1 (no)
CA (1) CA2145928C (no)
CZ (1) CZ287261B6 (no)
DE (2) DE59502637D1 (no)
DK (2) DK0816344T3 (no)
ES (2) ES2201229T3 (no)
FI (2) FI109119B (no)
HU (3) HU219986B (no)
NO (2) NO306461B1 (no)
PL (1) PL190855B1 (no)
PT (1) PT816344E (no)
SK (1) SK282208B6 (no)
TW (1) TW442474B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9402161D0 (en) 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
CA2145928C (en) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation
KR100606625B1 (ko) 1998-10-30 2006-07-28 론자 아게 4-[(2',5'-디아미노-6'-할로피리미딘-4'-일)아미노]-시클로펜트-2-에닐메탄올의 제조 방법
CA2348374C (en) * 1998-10-30 2009-04-07 Lonza Ag Method for producing 4- [(2',5'- diamino-6'- halopyrimidine- 4'-yl)amino]- cyclopent- 2-enylmethanols
ES2187112T3 (es) * 1998-12-21 2003-05-16 Lonza Ag Procedimiento para la preparacion de n-(amino-4,6-dihalogenopirimidin)-formamidas.
US6608199B2 (en) 2000-07-07 2003-08-19 Syngenta Limited Synthesis of chlorinated pyrimidines
JP2002223094A (ja) * 2001-01-25 2002-08-09 Yokohama Rubber Co Ltd:The 電波吸収体の構造
US6982331B2 (en) * 2001-06-08 2006-01-03 Syngenta Crop Protection, Inc. Synthesis of chlorinated pyrimidines
FR2849030A1 (fr) * 2002-12-20 2004-06-25 Isochem Sa Procede de preparation des n-(2-amino-4, 6-dihalogenopyrimidin-5-yl) formamides
WO2004103979A1 (ja) * 2003-05-26 2004-12-02 Sumitomo Chemical Company, Limited Ｎ－（２－アミノ－４，６－ジクロロピリミジン－５－イル）ホルムアミドの製造方法
DE102004002055A1 (de) * 2004-01-15 2005-08-11 Degussa Ag Verfahren zur Herstellung von 2-Amino-4,6-dichlor-5-formamidopyrimidin
CN101003511B (zh) * 2007-01-19 2010-06-09 中国科学院上海有机化学研究所 制备2-氨基-4,6-二氯-5-甲酰氨基嘧啶的方法
CN102127022A (zh) * 2010-12-30 2011-07-20 苏州开元民生科技股份有限公司 2-氨基-4,6-二氯-5-甲酰胺基嘧啶的合成方法
CZ305457B6 (cs) * 2011-02-28 2015-09-30 Ústav organické chemie a biochemie, Akademie věd ČR v. v. i. Pyrimidinové sloučeniny inhibující tvorbu oxidu dusnatého a prostaglandinu E2, způsob výroby a použití
CZ305750B6 (cs) * 2012-01-26 2016-03-02 Ústav Organické Chemie A Biochemie Akademie Věd Čr, V.V.I. Způsob výroby N-9 substituovaných analogů purinu
CN102702110A (zh) * 2012-05-24 2012-10-03 盛世泰科生物医药技术(苏州)有限公司 一种4-氨基-5,6-二氯嘧啶的制备方法
WO2014023681A1 (en) * 2012-08-06 2014-02-13 Enantia, S.L. A process for the preparation of an intermediate for a triazolopyrimidine carbonucleoside

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process
CZ287049B6 (cs) * 1992-01-22 2000-08-16 Lonza A. G. N-5-chráněné 2,5-diamino-4,6-dichlorpyrimidiny a způsob jejich přípravy
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
CA2145928C (en) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation

Also Published As

Publication number Publication date
CN1113237A (zh) 1995-12-13
KR100327996B1 (ko) 2002-07-27
NO984588D0 (no) 1998-10-01
PL308394A1 (en) 1995-10-30
EP0684236A3 (de) 1996-07-17
KR950032143A (ko) 1995-12-20
CA2145928C (en) 2007-10-09
HU0003725D0 (no) 1995-04-26
HU9501194D0 (en) 1995-06-28
NO306461B1 (no) 1999-11-08
NO306859B1 (no) 2000-01-03
US5663340A (en) 1997-09-02
FI109693B (fi) 2002-09-30
FI20011433A (fi) 2001-07-02
PT816344E (pt) 2003-10-31
JP3811966B2 (ja) 2006-08-23
CZ287261B6 (en) 2000-10-11
JP4525625B2 (ja) 2010-08-18
NO951594D0 (no) 1995-04-26
US5744601A (en) 1998-04-28
CA2145928A1 (en) 1995-10-28
HUT70700A (en) 1995-10-30
ATE167672T1 (de) 1998-07-15
EP0684236B2 (de) 2007-12-26
EP0684236A2 (de) 1995-11-29
EP0816344B1 (de) 2003-06-18
JP2006199707A (ja) 2006-08-03
EP0684236B1 (de) 1998-06-24
HU219712B (hu) 2001-06-28
EP0816344A1 (de) 1998-01-07
FI952009A0 (fi) 1995-04-27
SK54195A3 (en) 1995-11-08
DE59502637D1 (de) 1998-07-30
CZ106795A3 (en) 1995-11-15
US5583226A (en) 1996-12-10
ATE243200T1 (de) 2003-07-15
SK282208B6 (sk) 2001-12-03
DK0684236T4 (da) 2008-05-05
ES2120099T3 (es) 1998-10-16
US5693800A (en) 1997-12-02
CN1259517A (zh) 2000-07-12
FI952009A (fi) 1995-10-28
CN1193991C (zh) 2005-03-23
HU0003724D0 (no) 2000-11-28
HU219716B (hu) 2001-06-28
CN1065862C (zh) 2001-05-16
FI109119B (fi) 2002-05-31
ES2120099T5 (es) 2008-05-16
JPH07300466A (ja) 1995-11-14
DK0684236T3 (da) 1998-11-02
NO951594L (no) 1995-10-30
DK0816344T3 (da) 2003-10-06
DE59510726D1 (de) 2003-07-24
HU219986B (hu) 2001-10-28
TW442474B (en) 2001-06-23
PL190855B1 (pl) 2006-02-28
ES2201229T3 (es) 2004-03-16

Similar Documents

Publication Publication Date Title
NO306859B1 (no) Fremgangsmåte for fremstilling av 2,5-di-amino-4,6-diklorpyrimidin
DE69214925T2 (de) Verfahren zur Herstellung von Pyrrolo (2,3-d)Pyrimidinen
GR3030364T3 (en) Indole-7-carboxamide derivatives as analgesics.
DK184388A (da) 3h-1,2,3-triazolooe4,5-daapyrimidiner
MX9705649A (es) Compuestos de fenilo substituidos como antagonistas de endotelinas.
ATE78473T1 (de) Verfahren zur herstellung von 2,4-diamino-6-(1piperidinyl)-pyramidin-n-oxid.
HUT71096A (en) Process for the preparation of 2-amino-4,6-dichloro-pyrimidine
ATE123025T1 (de) 2-amino-n-(((4-(aminocarbonyl)pyrimidin-2- yl>amino>alkyl>-pyrimidin-4- carbonsäureamidderivate, ihre herstellung und ihre anwendung in der therapeutica.
EA199800090A1 (ru) Способ получения 4,6-диметокси-2-((феноксикарбонил)амино)пиримидина
DE59307402D1 (de) Lösliche Salze von 4-Amino-2-(4,4-dimethyl-imidazolidin-2-on-1-yl)-pyrimidin-5 -carbonsäure- N-methyl-N-(3-trifluormethyl-phenyl)- amid, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und Ausgangsprodukte
ZA944951B (en) A process for preparing 5-chloro-4-hydroxypyrimidines, 2-chloro enamines as intermediates in this process and their use.
ES8800929A1 (es) Procedimiento para la obtencion de la 3,3-dimetil-n-(4-(4-(2-pirimidinil)-1-piperazinil)butil)glutarimida

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees