DK0684236T4 - Fremgangsmåde til fremstilling af N-(2-amino-4,6-dichlorpyrimidin-5-yl)formamid - Google Patents

Fremgangsmåde til fremstilling af N-(2-amino-4,6-dichlorpyrimidin-5-yl)formamid

Info

Publication number
DK0684236T4
DK0684236T4 DK95106220T DK95106220T DK0684236T4 DK 0684236 T4 DK0684236 T4 DK 0684236T4 DK 95106220 T DK95106220 T DK 95106220T DK 95106220 T DK95106220 T DK 95106220T DK 0684236 T4 DK0684236 T4 DK 0684236T4
Authority
DK
Denmark
Prior art keywords
formula
amino
alkyl
dichloropyrimidin
formamide
Prior art date
Application number
DK95106220T
Other languages
English (en)
Other versions
DK0684236T3 (da
Inventor
Gerhard Dr Stucky
Rene Dr Imwinkelried
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4207186&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0684236(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lonza Ag filed Critical Lonza Ag
Application granted granted Critical
Publication of DK0684236T3 publication Critical patent/DK0684236T3/da
Publication of DK0684236T4 publication Critical patent/DK0684236T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
DK95106220T 1994-04-27 1995-04-25 Fremgangsmåde til fremstilling af N-(2-amino-4,6-dichlorpyrimidin-5-yl)formamid DK0684236T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH129994 1994-04-27

Publications (2)

Publication Number Publication Date
DK0684236T3 DK0684236T3 (da) 1998-11-02
DK0684236T4 true DK0684236T4 (da) 2008-05-05

Family

ID=4207186

Family Applications (2)

Application Number Title Priority Date Filing Date
DK95106220T DK0684236T4 (da) 1994-04-27 1995-04-25 Fremgangsmåde til fremstilling af N-(2-amino-4,6-dichlorpyrimidin-5-yl)formamid
DK97114001T DK0816344T3 (da) 1994-04-27 1995-04-25 Fremgangsmåde til fremstilling af 2,5-diamino-4,6-dichlorpyrimidin

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK97114001T DK0816344T3 (da) 1994-04-27 1995-04-25 Fremgangsmåde til fremstilling af 2,5-diamino-4,6-dichlorpyrimidin

Country Status (18)

Country Link
US (4) US5583226A (da)
EP (2) EP0684236B2 (da)
JP (2) JP3811966B2 (da)
KR (1) KR100327996B1 (da)
CN (2) CN1193991C (da)
AT (2) ATE167672T1 (da)
CA (1) CA2145928C (da)
CZ (1) CZ287261B6 (da)
DE (2) DE59510726D1 (da)
DK (2) DK0684236T4 (da)
ES (2) ES2201229T3 (da)
FI (2) FI109119B (da)
HU (3) HU219716B (da)
NO (2) NO306461B1 (da)
PL (1) PL190855B1 (da)
PT (1) PT816344E (da)
SK (1) SK282208B6 (da)
TW (1) TW442474B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
CA2145928C (en) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation
KR100606625B1 (ko) 1998-10-30 2006-07-28 론자 아게 4-[(2',5'-디아미노-6'-할로피리미딘-4'-일)아미노]-시클로펜트-2-에닐메탄올의 제조 방법
IL142760A (en) * 1998-10-30 2005-12-18 Lonza Ag Method for producing 4-Ä(2',5'-diamino-6'- halopyrimidine-4' -yl) aminoÜ-cyclopent -2- enyl-methanols
DK1013647T3 (da) 1998-12-21 2003-03-10 Lonza Ag Fremgangsmåde til fremstilling af N-(amino-4,6-dihalogenpyrimidin)-formamider
US6608199B2 (en) 2000-07-07 2003-08-19 Syngenta Limited Synthesis of chlorinated pyrimidines
JP2002223094A (ja) * 2001-01-25 2002-08-09 Yokohama Rubber Co Ltd:The 電波吸収体の構造
US6982331B2 (en) * 2001-06-08 2006-01-03 Syngenta Crop Protection, Inc. Synthesis of chlorinated pyrimidines
FR2849030A1 (fr) * 2002-12-20 2004-06-25 Isochem Sa Procede de preparation des n-(2-amino-4, 6-dihalogenopyrimidin-5-yl) formamides
JPWO2004103979A1 (ja) * 2003-05-26 2006-07-20 住友化学株式会社 Ｎ−（２−アミノ−４，６−ジクロロピリミジン−５−イル）ホルムアミドの製造方法
DE102004002055A1 (de) * 2004-01-15 2005-08-11 Degussa Ag Verfahren zur Herstellung von 2-Amino-4,6-dichlor-5-formamidopyrimidin
CN101003511B (zh) * 2007-01-19 2010-06-09 中国科学院上海有机化学研究所 制备2-氨基-4,6-二氯-5-甲酰氨基嘧啶的方法
CN102127022A (zh) * 2010-12-30 2011-07-20 苏州开元民生科技股份有限公司 2-氨基-4,6-二氯-5-甲酰胺基嘧啶的合成方法
CZ305457B6 (cs) * 2011-02-28 2015-09-30 Ústav organické chemie a biochemie, Akademie věd ČR v. v. i. Pyrimidinové sloučeniny inhibující tvorbu oxidu dusnatého a prostaglandinu E2, způsob výroby a použití
CZ305750B6 (cs) * 2012-01-26 2016-03-02 Ústav Organické Chemie A Biochemie Akademie Věd Čr, V.V.I. Způsob výroby N-9 substituovaných analogů purinu
CN102702110A (zh) * 2012-05-24 2012-10-03 盛世泰科生物医药技术(苏州)有限公司 一种4-氨基-5,6-二氯嘧啶的制备方法
EP2882720A1 (en) * 2012-08-06 2015-06-17 Enantia, S.L. A process for the preparation of an intermediate for a triazolopyrimidine carbonucleoside

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process
SK279618B6 (sk) * 1992-01-22 1999-01-11 Lonza A.G. (Dir.:Basel) N-5-chránené 2,5-diamino-4,6-dichlórpyrimidíny a s
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
CA2145928C (en) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation

Also Published As

Publication number Publication date
HU0003725D0 (da) 1995-04-26
EP0816344B1 (de) 2003-06-18
HU9501194D0 (en) 1995-06-28
NO984588D0 (no) 1998-10-01
TW442474B (en) 2001-06-23
ATE243200T1 (de) 2003-07-15
JP4525625B2 (ja) 2010-08-18
HU219716B (hu) 2001-06-28
ES2201229T3 (es) 2004-03-16
CN1113237A (zh) 1995-12-13
US5583226A (en) 1996-12-10
HUT70700A (en) 1995-10-30
DK0684236T3 (da) 1998-11-02
US5744601A (en) 1998-04-28
CA2145928A1 (en) 1995-10-28
HU219712B (hu) 2001-06-28
ES2120099T3 (es) 1998-10-16
KR950032143A (ko) 1995-12-20
CN1259517A (zh) 2000-07-12
CN1065862C (zh) 2001-05-16
SK54195A3 (en) 1995-11-08
JPH07300466A (ja) 1995-11-14
JP2006199707A (ja) 2006-08-03
PL190855B1 (pl) 2006-02-28
NO951594D0 (no) 1995-04-26
HU219986B (hu) 2001-10-28
ES2120099T5 (es) 2008-05-16
PT816344E (pt) 2003-10-31
US5693800A (en) 1997-12-02
FI952009A0 (fi) 1995-04-27
FI952009A (fi) 1995-10-28
CZ106795A3 (en) 1995-11-15
PL308394A1 (en) 1995-10-30
DE59502637D1 (de) 1998-07-30
US5663340A (en) 1997-09-02
DE59510726D1 (de) 2003-07-24
EP0816344A1 (de) 1998-01-07
SK282208B6 (sk) 2001-12-03
HU0003724D0 (da) 2000-11-28
DK0816344T3 (da) 2003-10-06
NO306461B1 (no) 1999-11-08
NO306859B1 (no) 2000-01-03
FI109693B (fi) 2002-09-30
EP0684236B2 (de) 2007-12-26
EP0684236A3 (de) 1996-07-17
KR100327996B1 (ko) 2002-07-27
NO951594L (no) 1995-10-30
FI109119B (fi) 2002-05-31
EP0684236B1 (de) 1998-06-24
FI20011433A (fi) 2001-07-02
CZ287261B6 (en) 2000-10-11
CA2145928C (en) 2007-10-09
JP3811966B2 (ja) 2006-08-23
ATE167672T1 (de) 1998-07-15
NO984588L (no) 1995-10-30
EP0684236A2 (de) 1995-11-29
CN1193991C (zh) 2005-03-23

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