NO791223L - Fremgangsmaate for fremstilling av beta-laktamforbindelser - Google Patents

Fremgangsmaate for fremstilling av beta-laktamforbindelser

Info

Publication number
NO791223L
NO791223L NO79791223A NO791223A NO791223L NO 791223 L NO791223 L NO 791223L NO 79791223 A NO79791223 A NO 79791223A NO 791223 A NO791223 A NO 791223A NO 791223 L NO791223 L NO 791223L
Authority
NO
Norway
Prior art keywords
oxo
carboxylic acid
thia
mixture
added
Prior art date
Application number
NO79791223A
Other languages
English (en)
Norwegian (no)
Inventor
Hiroshi Ishikawa
Fujio Tabusa
Kazuyuki Nakagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP53043624A external-priority patent/JPS6034957B2/ja
Priority claimed from JP53110464A external-priority patent/JPS6037118B2/ja
Priority claimed from JP53141785A external-priority patent/JPS6037119B2/ja
Priority claimed from JP53145638A external-priority patent/JPS5951959B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO791223L publication Critical patent/NO791223L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
NO79791223A 1978-04-12 1979-04-10 Fremgangsmaate for fremstilling av beta-laktamforbindelser NO791223L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP53043624A JPS6034957B2 (ja) 1978-04-12 1978-04-12 ペニシラン酸誘導体
JP53110464A JPS6037118B2 (ja) 1978-09-07 1978-09-07 ペニシラン酸誘導体
JP53141785A JPS6037119B2 (ja) 1978-11-16 1978-11-16 ペニシラン酸誘導体
JP53145638A JPS5951959B2 (ja) 1978-11-24 1978-11-24 ペニシラン酸誘導体

Publications (1)

Publication Number Publication Date
NO791223L true NO791223L (no) 1979-10-15

Family

ID=27461393

Family Applications (2)

Application Number Title Priority Date Filing Date
NO79791223A NO791223L (no) 1978-04-12 1979-04-10 Fremgangsmaate for fremstilling av beta-laktamforbindelser
NO84840617A NO840617L (no) 1978-04-12 1984-02-20 Analogifremgangsmaate for fremstilling av farmakologisk aktive cefalosporinderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO84840617A NO840617L (no) 1978-04-12 1984-02-20 Analogifremgangsmaate for fremstilling av farmakologisk aktive cefalosporinderivater

Country Status (18)

Country Link
US (1) US4317820A (de)
AR (2) AR227005A1 (de)
AT (1) AT368159B (de)
AU (1) AU524795B2 (de)
CA (1) CA1133469A (de)
CH (1) CH642081A5 (de)
DE (1) DE2914218C2 (de)
DK (1) DK149479A (de)
ES (2) ES480281A1 (de)
FI (1) FI70219C (de)
FR (1) FR2422666A1 (de)
IT (1) IT1162605B (de)
MX (1) MX5704E (de)
NL (1) NL180589C (de)
NO (2) NO791223L (de)
PT (1) PT69473A (de)
SE (1) SE7903297L (de)
SU (1) SU1151212A3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792774A (en) * 1996-02-21 1998-08-11 Chiroscience Limited Quinolones and their therapeutic use
US6525049B2 (en) 2000-07-05 2003-02-25 Pharmacia & Upjohn Company Pyrroloquinolones as antiviral agents
ES2340531T3 (es) * 2005-10-21 2010-06-04 Glaxo Group Limited Compuestos triciclos peri-condensados utiles como agentes antibacterianos.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL175419C (nl) * 1971-10-23 1984-11-01 Bayer Ag Werkwijze ter bereiding of vervaardiging van antibiotisch werkzame farmaceutische preparaten, alsmede werkwijze ter bereiding van antibiotisch werkzame alfa-gesubstitueerde 6-(alfa-(3-acylureido)acetylamino) penicillanzuurderivaten.
US3780034A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing substituted cephalosporins
US3778432A (en) * 1971-12-13 1973-12-11 Merck & Co Inc Isocyanates and carbamates of penicillins and 3-cephem-4-carboxylic acids
BE793524A (fr) 1971-12-30 1973-06-29 Riker Laboratories Inc Acides benzoquinolizine-carboxyliques et leurs derives
US3954731A (en) * 1972-07-03 1976-05-04 Eli Lilly And Company Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids
US3917609A (en) 1973-06-27 1975-11-04 Minnesota Mining & Mfg Pyrroloquinoline carboxylic acids and derivatives
US4062842A (en) * 1973-09-06 1977-12-13 E. R. Squibb & Sons, Inc. Method for preparing 7-substituted cephalosporins and 6-substituted penicillins by replacement of sulfur-containing groups
DE2559932C2 (de) 1974-05-09 1983-04-21 Toyama Chemical Co. Ltd., Tokyo Cephalosporine, Verfahren zur Herstellung derselben und Mittel mit einem Gehalt derselben
US3962214A (en) * 1974-07-11 1976-06-08 Eli Lilly And Company Process for preparing amino substituted β-lactam antibiotics

Also Published As

Publication number Publication date
SE7903297L (sv) 1979-12-21
ES480281A1 (es) 1980-08-16
DK149479A (da) 1979-10-13
MX5704E (es) 1983-12-16
FR2422666B1 (de) 1983-02-04
NL180589B (nl) 1986-10-16
CA1133469A (en) 1982-10-12
NO840617L (no) 1979-10-15
NL7902906A (nl) 1979-10-16
IT1162605B (it) 1987-04-01
CH642081A5 (de) 1984-03-30
DE2914218A1 (de) 1979-10-25
AU4603879A (en) 1979-10-18
US4317820A (en) 1982-03-02
PT69473A (en) 1979-05-01
AU524795B2 (en) 1982-10-07
AR226883A1 (es) 1982-08-31
FI70219B (fi) 1986-02-28
AR227005A1 (es) 1982-09-15
FI791190A (fi) 1979-10-13
FI70219C (fi) 1986-09-15
NL180589C (nl) 1987-03-16
ATA269079A (de) 1982-01-15
DE2914218C2 (de) 1985-10-24
ES8200339A1 (es) 1981-11-16
IT7948691A0 (it) 1979-04-10
SU1151212A3 (ru) 1985-04-15
FR2422666A1 (fr) 1979-11-09
AT368159B (de) 1982-09-27
ES488833A0 (es) 1981-11-16

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