DK149479A - Fremgangsmaade til fremstilling af betalactamforbindelser eller farmaceutisk acceptable salte deraf - Google Patents

Fremgangsmaade til fremstilling af betalactamforbindelser eller farmaceutisk acceptable salte deraf

Info

Publication number
DK149479A
DK149479A DK149479A DK149479A DK149479A DK 149479 A DK149479 A DK 149479A DK 149479 A DK149479 A DK 149479A DK 149479 A DK149479 A DK 149479A DK 149479 A DK149479 A DK 149479A
Authority
DK
Denmark
Prior art keywords
betalactam
compounds
procedure
preparation
acceptable salts
Prior art date
Application number
DK149479A
Other languages
Danish (da)
English (en)
Inventor
H Ishikawa
F Tabusa
K Nakagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP53043624A external-priority patent/JPS6034957B2/ja
Priority claimed from JP53110464A external-priority patent/JPS6037118B2/ja
Priority claimed from JP53141785A external-priority patent/JPS6037119B2/ja
Priority claimed from JP53145638A external-priority patent/JPS5951959B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of DK149479A publication Critical patent/DK149479A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Cephalosporin Compounds (AREA)
DK149479A 1978-04-12 1979-04-10 Fremgangsmaade til fremstilling af betalactamforbindelser eller farmaceutisk acceptable salte deraf DK149479A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP53043624A JPS6034957B2 (ja) 1978-04-12 1978-04-12 ペニシラン酸誘導体
JP53110464A JPS6037118B2 (ja) 1978-09-07 1978-09-07 ペニシラン酸誘導体
JP53141785A JPS6037119B2 (ja) 1978-11-16 1978-11-16 ペニシラン酸誘導体
JP53145638A JPS5951959B2 (ja) 1978-11-24 1978-11-24 ペニシラン酸誘導体

Publications (1)

Publication Number Publication Date
DK149479A true DK149479A (da) 1979-10-13

Family

ID=27461393

Family Applications (1)

Application Number Title Priority Date Filing Date
DK149479A DK149479A (da) 1978-04-12 1979-04-10 Fremgangsmaade til fremstilling af betalactamforbindelser eller farmaceutisk acceptable salte deraf

Country Status (18)

Country Link
US (1) US4317820A (de)
AR (2) AR227005A1 (de)
AT (1) AT368159B (de)
AU (1) AU524795B2 (de)
CA (1) CA1133469A (de)
CH (1) CH642081A5 (de)
DE (1) DE2914218C2 (de)
DK (1) DK149479A (de)
ES (2) ES480281A1 (de)
FI (1) FI70219C (de)
FR (1) FR2422666A1 (de)
IT (1) IT1162605B (de)
MX (1) MX5704E (de)
NL (1) NL180589C (de)
NO (2) NO791223L (de)
PT (1) PT69473A (de)
SE (1) SE7903297L (de)
SU (1) SU1151212A3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792774A (en) * 1996-02-21 1998-08-11 Chiroscience Limited Quinolones and their therapeutic use
US6525049B2 (en) 2000-07-05 2003-02-25 Pharmacia & Upjohn Company Pyrroloquinolones as antiviral agents
PL1954697T3 (pl) * 2005-10-21 2010-07-30 Glaxo Group Ltd Peri skondensowane tricykliczne związki użyteczne jako środki przeciwbakteryjne

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL175419C (nl) * 1971-10-23 1984-11-01 Bayer Ag Werkwijze ter bereiding of vervaardiging van antibiotisch werkzame farmaceutische preparaten, alsmede werkwijze ter bereiding van antibiotisch werkzame alfa-gesubstitueerde 6-(alfa-(3-acylureido)acetylamino) penicillanzuurderivaten.
US3780034A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing substituted cephalosporins
US3778432A (en) * 1971-12-13 1973-12-11 Merck & Co Inc Isocyanates and carbamates of penicillins and 3-cephem-4-carboxylic acids
BE793524A (fr) 1971-12-30 1973-06-29 Riker Laboratories Inc Acides benzoquinolizine-carboxyliques et leurs derives
US3954731A (en) * 1972-07-03 1976-05-04 Eli Lilly And Company Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids
US3917609A (en) 1973-06-27 1975-11-04 Minnesota Mining & Mfg Pyrroloquinoline carboxylic acids and derivatives
US4062842A (en) * 1973-09-06 1977-12-13 E. R. Squibb & Sons, Inc. Method for preparing 7-substituted cephalosporins and 6-substituted penicillins by replacement of sulfur-containing groups
DE2559932C2 (de) 1974-05-09 1983-04-21 Toyama Chemical Co. Ltd., Tokyo Cephalosporine, Verfahren zur Herstellung derselben und Mittel mit einem Gehalt derselben
US3962214A (en) * 1974-07-11 1976-06-08 Eli Lilly And Company Process for preparing amino substituted β-lactam antibiotics

Also Published As

Publication number Publication date
FR2422666A1 (fr) 1979-11-09
AR227005A1 (es) 1982-09-15
MX5704E (es) 1983-12-16
FI70219C (fi) 1986-09-15
NL180589C (nl) 1987-03-16
CH642081A5 (de) 1984-03-30
ES8200339A1 (es) 1981-11-16
FR2422666B1 (de) 1983-02-04
NL180589B (nl) 1986-10-16
FI70219B (fi) 1986-02-28
IT1162605B (it) 1987-04-01
CA1133469A (en) 1982-10-12
AT368159B (de) 1982-09-27
ATA269079A (de) 1982-01-15
FI791190A (fi) 1979-10-13
AR226883A1 (es) 1982-08-31
AU524795B2 (en) 1982-10-07
IT7948691A0 (it) 1979-04-10
US4317820A (en) 1982-03-02
NO791223L (no) 1979-10-15
SE7903297L (sv) 1979-12-21
ES480281A1 (es) 1980-08-16
AU4603879A (en) 1979-10-18
DE2914218C2 (de) 1985-10-24
SU1151212A3 (ru) 1985-04-15
ES488833A0 (es) 1981-11-16
PT69473A (en) 1979-05-01
DE2914218A1 (de) 1979-10-25
NL7902906A (nl) 1979-10-16
NO840617L (no) 1979-10-15

Similar Documents

Publication Publication Date Title
DK160940C (da) Analogifremgangsmaade til fremstilling af benzoheterocycliske forbindelser eller farmaceutisk acceptable salte deraf
DK152495C (da) Analogifremgangsmaade til fremstilling af n2-arylsulfonyl-l-argininamider eller farmaceutisk tolerable salte deraf
DK158225C (da) Analogifremgangsmaade til fremstilling af carbostyrilderivater
DK127982A (da) Fremgangsmaade til fremstilling af flercycliske forbindelser eller salte,estre eller amider deraf
DK15279A (da) Fremgangsmaade til fremstilling af tetrahydropyridinylindolderivater eller additionssalte deraf
DK152114C (da) Analogifremgangsmaade til fremstilling af propenylaminer eller farmaceutisk acceptable salte deraf
DK552581A (da) Fremgangsmaade til fremstilling af 3-pyridylaklyl-indol-forbindelser eller farmaceutisk acceptable salte deraf
DK273479A (da) Fremgangsmaade til fremstilling af 5-phenylpyrazol-forbindelser eller salte deraf
DK503080A (da) Fremgangsmaade til fremstilling af imdazolderivater eller salte deraf
DK158658C (da) Analogifremgangsmaade til fremstilling af 9-aminoalkylfluorener eller farmaceutisk acceptable salte deraf
DK155670C (da) Analogifremgangsmaade til fremstilling af sesquiterpenderivater eller farmaceutisk acceptable salte deraf
DK27078A (da) Fremgangsmaade til fremstilling af imidazoquinoliner eller salte deraf
DK324979A (da) Fremgangsmaade til fremstilling af imidazoquinoxaliner eller salte deraf
DK232777A (da) Fremgangsmade til fremstilling af imidazothiaziner eller farmaceutisk acceptable salte deraf
DK511878A (da) Fremgangsmaade til fremstilling af imidazobenzoazepiner eller salte deraf
DK223177A (da) Fremgangsmade til fremstilling af p-acylaminobenzamid-forbindelser eller salte deraf
DK115379A (da) Fremgangsmaade til fremstilling af dilignoler eller dilignollignende forbindelser eller salte heraf
DK162102C (da) Analogifremgangsmaade til fremstilling af 3-o-(beta-d-glucoronopyranosyl)-sojasapogenol b eller farmaceutisk acceptable salte deraf
DK232677A (da) Fremgangsmade til fremstilling af dihydro eller tetrahydroiminothiaziner eller farmaceutisk acceptable salte deraf
DK232877A (da) Fremgangsmade til fremstilling af 2-imino-3-aminothiazolidiner eller farmaceutisk acceptable salte deraf
DK150521C (da) Analogifremgangsmaade til fremstilling af n2-arylsulfonyl-l-argininamider eller farmaceutisk acceptable salte deraf
DK157021C (da) Analogifremgangsmaade til fremstilling af 2,3-polymethylen-4-oxo-4h-pyrido- eller -azepinooe1,2-aaapyrimidiner eller farmaceutisk acceptable syreadditionssalte eller kvaternaere salte deraf
DK149823C (da) Fremgangsmaade til fremstilling af kijanimicin eller farmaceutisk acceptable salte heraf
DK151254C (da) Analogifremgangsmaade til fremstilling af 2-hydroxymethyl-pyrazin-derivater eller farmaceutisk acceptable salte deraf
DK224381A (da) Fremgangsmaade til fremstilling af benzazolderivater eller salte deraf

Legal Events

Date Code Title Description
ARF Application refused
PHB Application deemed withdrawn due to non-payment or other reasons