AR227005A1 - Un metodo para preparar un oxo-(pirido 3,2,1-jk-carbazol o benzo(ij)-quinolizina o pirrolo 3,2,1-ij-quinolina)-carboxamido-2-fenilacetamido-oxo-tia-1-azabiciclo-(heptano u oct-2-ene)-2-acido carboxilico - Google Patents

Un metodo para preparar un oxo-(pirido 3,2,1-jk-carbazol o benzo(ij)-quinolizina o pirrolo 3,2,1-ij-quinolina)-carboxamido-2-fenilacetamido-oxo-tia-1-azabiciclo-(heptano u oct-2-ene)-2-acido carboxilico

Info

Publication number
AR227005A1
AR227005A1 AR276166A AR27616679A AR227005A1 AR 227005 A1 AR227005 A1 AR 227005A1 AR 276166 A AR276166 A AR 276166A AR 27616679 A AR27616679 A AR 27616679A AR 227005 A1 AR227005 A1 AR 227005A1
Authority
AR
Argentina
Prior art keywords
oxo
quinolizina
fenilacetamido
azabiciclo
quinolina
Prior art date
Application number
AR276166A
Other languages
English (en)
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP53043624A external-priority patent/JPS6034957B2/ja
Priority claimed from JP53110464A external-priority patent/JPS6037118B2/ja
Priority claimed from JP53141785A external-priority patent/JPS6037119B2/ja
Priority claimed from JP53145638A external-priority patent/JPS5951959B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of AR227005A1 publication Critical patent/AR227005A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AR276166A 1978-04-12 1979-04-11 Un metodo para preparar un oxo-(pirido 3,2,1-jk-carbazol o benzo(ij)-quinolizina o pirrolo 3,2,1-ij-quinolina)-carboxamido-2-fenilacetamido-oxo-tia-1-azabiciclo-(heptano u oct-2-ene)-2-acido carboxilico AR227005A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP53043624A JPS6034957B2 (ja) 1978-04-12 1978-04-12 ペニシラン酸誘導体
JP53110464A JPS6037118B2 (ja) 1978-09-07 1978-09-07 ペニシラン酸誘導体
JP53141785A JPS6037119B2 (ja) 1978-11-16 1978-11-16 ペニシラン酸誘導体
JP53145638A JPS5951959B2 (ja) 1978-11-24 1978-11-24 ペニシラン酸誘導体

Publications (1)

Publication Number Publication Date
AR227005A1 true AR227005A1 (es) 1982-09-15

Family

ID=27461393

Family Applications (2)

Application Number Title Priority Date Filing Date
AR276166A AR227005A1 (es) 1978-04-12 1979-04-11 Un metodo para preparar un oxo-(pirido 3,2,1-jk-carbazol o benzo(ij)-quinolizina o pirrolo 3,2,1-ij-quinolina)-carboxamido-2-fenilacetamido-oxo-tia-1-azabiciclo-(heptano u oct-2-ene)-2-acido carboxilico
AR284582A AR226883A1 (es) 1978-04-12 1981-03-11 Metodo para preparar un oxo-(pirido(3,2,1-jk)carbazol o benzo(ij)quinolizina o pirrolo(3,2,1-ij)quinolina)-carboxamido-2-fenilacetamido-oxo-tia-1-azabiciclo-(heptano u oct-2-ene)-2-acido carboxilico

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR284582A AR226883A1 (es) 1978-04-12 1981-03-11 Metodo para preparar un oxo-(pirido(3,2,1-jk)carbazol o benzo(ij)quinolizina o pirrolo(3,2,1-ij)quinolina)-carboxamido-2-fenilacetamido-oxo-tia-1-azabiciclo-(heptano u oct-2-ene)-2-acido carboxilico

Country Status (18)

Country Link
US (1) US4317820A (es)
AR (2) AR227005A1 (es)
AT (1) AT368159B (es)
AU (1) AU524795B2 (es)
CA (1) CA1133469A (es)
CH (1) CH642081A5 (es)
DE (1) DE2914218C2 (es)
DK (1) DK149479A (es)
ES (2) ES480281A1 (es)
FI (1) FI70219C (es)
FR (1) FR2422666A1 (es)
IT (1) IT1162605B (es)
MX (1) MX5704E (es)
NL (1) NL180589C (es)
NO (2) NO791223L (es)
PT (1) PT69473A (es)
SE (1) SE7903297L (es)
SU (1) SU1151212A3 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792774A (en) * 1996-02-21 1998-08-11 Chiroscience Limited Quinolones and their therapeutic use
US6525049B2 (en) 2000-07-05 2003-02-25 Pharmacia & Upjohn Company Pyrroloquinolones as antiviral agents
PL1954697T3 (pl) * 2005-10-21 2010-07-30 Glaxo Group Ltd Peri skondensowane tricykliczne związki użyteczne jako środki przeciwbakteryjne

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL175419C (nl) * 1971-10-23 1984-11-01 Bayer Ag Werkwijze ter bereiding of vervaardiging van antibiotisch werkzame farmaceutische preparaten, alsmede werkwijze ter bereiding van antibiotisch werkzame alfa-gesubstitueerde 6-(alfa-(3-acylureido)acetylamino) penicillanzuurderivaten.
US3780034A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing substituted cephalosporins
US3778432A (en) * 1971-12-13 1973-12-11 Merck & Co Inc Isocyanates and carbamates of penicillins and 3-cephem-4-carboxylic acids
BE793524A (fr) 1971-12-30 1973-06-29 Riker Laboratories Inc Acides benzoquinolizine-carboxyliques et leurs derives
US3954731A (en) * 1972-07-03 1976-05-04 Eli Lilly And Company Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids
US3917609A (en) 1973-06-27 1975-11-04 Minnesota Mining & Mfg Pyrroloquinoline carboxylic acids and derivatives
US4062842A (en) * 1973-09-06 1977-12-13 E. R. Squibb & Sons, Inc. Method for preparing 7-substituted cephalosporins and 6-substituted penicillins by replacement of sulfur-containing groups
DE2559932C2 (de) 1974-05-09 1983-04-21 Toyama Chemical Co. Ltd., Tokyo Cephalosporine, Verfahren zur Herstellung derselben und Mittel mit einem Gehalt derselben
US3962214A (en) * 1974-07-11 1976-06-08 Eli Lilly And Company Process for preparing amino substituted β-lactam antibiotics

Also Published As

Publication number Publication date
NO791223L (no) 1979-10-15
CA1133469A (en) 1982-10-12
FI70219C (fi) 1986-09-15
DE2914218A1 (de) 1979-10-25
ES8200339A1 (es) 1981-11-16
ATA269079A (de) 1982-01-15
IT1162605B (it) 1987-04-01
ES480281A1 (es) 1980-08-16
FI70219B (fi) 1986-02-28
SU1151212A3 (ru) 1985-04-15
PT69473A (en) 1979-05-01
NO840617L (no) 1979-10-15
ES488833A0 (es) 1981-11-16
NL7902906A (nl) 1979-10-16
NL180589B (nl) 1986-10-16
AU524795B2 (en) 1982-10-07
US4317820A (en) 1982-03-02
NL180589C (nl) 1987-03-16
SE7903297L (sv) 1979-12-21
FI791190A (fi) 1979-10-13
DK149479A (da) 1979-10-13
FR2422666A1 (fr) 1979-11-09
AU4603879A (en) 1979-10-18
MX5704E (es) 1983-12-16
AT368159B (de) 1982-09-27
DE2914218C2 (de) 1985-10-24
FR2422666B1 (es) 1983-02-04
AR226883A1 (es) 1982-08-31
IT7948691A0 (it) 1979-04-10
CH642081A5 (de) 1984-03-30

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