NO752731L - - Google Patents

Info

Publication number
NO752731L
NO752731L NO752731A NO752731A NO752731L NO 752731 L NO752731 L NO 752731L NO 752731 A NO752731 A NO 752731A NO 752731 A NO752731 A NO 752731A NO 752731 L NO752731 L NO 752731L
Authority
NO
Norway
Application number
NO752731A
Other languages
Norwegian (no)
Other versions
NO143460B (no
NO143460C (no
Inventor
H Merz
A Langbein
G Walther
K Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of NO752731L publication Critical patent/NO752731L/no
Publication of NO143460B publication Critical patent/NO143460B/no
Publication of NO143460C publication Critical patent/NO143460C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO752731A 1974-08-05 1975-08-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner. NO143460C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2437610A DE2437610A1 (de) 1974-08-05 1974-08-05 Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (3)

Publication Number Publication Date
NO752731L true NO752731L (pt) 1976-02-06
NO143460B NO143460B (no) 1980-11-10
NO143460C NO143460C (no) 1981-02-18

Family

ID=5922448

Family Applications (1)

Application Number Title Priority Date Filing Date
NO752731A NO143460C (no) 1974-08-05 1975-08-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner.

Country Status (27)

Country Link
US (1) US3982005A (pt)
JP (1) JPS60358B2 (pt)
AT (1) AT348140B (pt)
BE (1) BE832099R (pt)
BG (3) BG25088A3 (pt)
CA (1) CA1049008A (pt)
CH (7) CH613963A5 (pt)
CS (1) CS189717B2 (pt)
DD (1) DD122685A5 (pt)
DE (1) DE2437610A1 (pt)
DK (1) DK138992C (pt)
ES (6) ES452766A1 (pt)
FI (1) FI63229C (pt)
FR (1) FR2320096A2 (pt)
GB (1) GB1513950A (pt)
HU (1) HU177952B (pt)
IE (1) IE42216B1 (pt)
IL (1) IL47860A (pt)
LU (1) LU73138A1 (pt)
NL (1) NL7509249A (pt)
NO (1) NO143460C (pt)
PH (1) PH13687A (pt)
PL (3) PL99816B1 (pt)
RO (3) RO67390A (pt)
SE (1) SE425392B (pt)
SU (3) SU591147A3 (pt)
ZA (1) ZA754997B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
NL7804509A (nl) * 1978-04-26 1979-10-30 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
JPS5636521A (en) * 1979-08-31 1981-04-09 Shin Etsu Chem Co Ltd Production of alkenyloxy group-containing organopolysiloxane
ATE554078T1 (de) 2007-07-26 2012-05-15 Vitae Pharmaceuticals Inc Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern
CL2008003407A1 (es) 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
AR071236A1 (es) 2008-05-01 2010-06-02 Vitae Pharmaceuticals Inc Inhibidores ciclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
AR071609A1 (es) 2008-05-01 2010-06-30 Vitae Pharmaceuticals Inc Inhibidores ciclicos de 11(beta) -hidroxiesteroide deshidrogenasa 1
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
WO2010010157A2 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
CA2730499A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) * 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives
CN116507689A (zh) 2020-11-26 2023-07-28 信越化学工业株式会社 室温固化性有机聚硅氧烷组合物及物品以及水解性有机硅烷化合物及其制造方法
WO2023032745A1 (ja) 2021-09-03 2023-03-09 信越化学工業株式会社 オルガノポリシロキサン化合物、室温硬化性オルガノポリシロキサン組成物、及び物品

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (pt) * 1958-09-22
US3700734A (en) * 1969-01-23 1972-10-24 Merck & Co Inc 2{40 -hydroxy-2,3,5-trimethyl-6,7-benzomorphan
DE2105743C3 (de) * 1971-02-08 1979-11-29 Boehringer Sohn Ingelheim 2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung
CS166804B2 (pt) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
DE2200596A1 (de) * 1972-01-07 1973-07-12 Boehringer Sohn Ingelheim N-(furyl-methyl)-2'-hydroxy-5-phenyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2217420C3 (de) * 1972-04-12 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2229695A1 (de) * 1972-06-19 1974-01-31 Boehringer Sohn Ingelheim 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
IE42216B1 (en) 1980-07-02
RO72736A (ro) 1982-09-09
RO72735A (ro) 1982-09-09
PH13687A (en) 1980-09-01
RO67390A (ro) 1981-06-30
HU177952B (en) 1982-02-28
BG25088A3 (en) 1978-07-12
ES452764A1 (es) 1977-10-16
NO143460B (no) 1980-11-10
PL99819B1 (pl) 1978-08-31
FR2320096A2 (fr) 1977-03-04
NL7509249A (nl) 1976-02-09
SU587858A3 (ru) 1978-01-05
SE425392B (sv) 1982-09-27
DK352875A (da) 1976-02-06
PL99816B1 (pl) 1978-08-31
IL47860A0 (en) 1975-11-25
ES452765A1 (es) 1977-10-16
JPS60358B2 (ja) 1985-01-07
DE2437610A1 (de) 1976-02-26
GB1513950A (en) 1978-06-14
CH615679A5 (pt) 1980-02-15
CH615677A5 (pt) 1980-02-15
BE832099R (fr) 1976-02-04
DD122685A5 (pt) 1976-10-20
CA1049008A (en) 1979-02-20
CH616421A5 (pt) 1980-03-31
CH615678A5 (pt) 1980-02-15
ES452767A1 (es) 1977-10-01
IL47860A (en) 1979-01-31
CH616420A5 (pt) 1980-03-31
SU591147A3 (ru) 1978-01-30
AU8364675A (en) 1977-02-10
SU587859A3 (ru) 1978-01-05
FI63229C (fi) 1983-05-10
ZA754997B (en) 1977-04-27
AT348140B (de) 1979-01-25
ES452768A1 (es) 1977-10-01
ATA523775A (de) 1978-06-15
ES452763A1 (es) 1977-10-01
JPS5139673A (en) 1976-04-02
CH615680A5 (pt) 1980-02-15
FR2320096B2 (pt) 1978-09-01
NO143460C (no) 1981-02-18
CS189717B2 (en) 1979-04-30
BG25090A3 (en) 1978-07-12
ES452766A1 (es) 1977-10-01
FI63229B (fi) 1983-01-31
DK138992B (da) 1978-11-27
PL99838B1 (pl) 1978-08-31
US3982005A (en) 1976-09-21
IE42216L (en) 1976-02-05
SE7508789L (sv) 1976-02-10
LU73138A1 (pt) 1977-04-13
BG25089A3 (en) 1978-07-12
CH613963A5 (pt) 1979-10-31
FI752211A (pt) 1976-02-06
DK138992C (da) 1979-04-30

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