NO332191B1 - Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi - Google Patents

Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi Download PDF

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Publication number
NO332191B1
NO332191B1 NO20040822A NO20040822A NO332191B1 NO 332191 B1 NO332191 B1 NO 332191B1 NO 20040822 A NO20040822 A NO 20040822A NO 20040822 A NO20040822 A NO 20040822A NO 332191 B1 NO332191 B1 NO 332191B1
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NO
Norway
Prior art keywords
photosensitizing agent
pharmaceutically acceptable
acceptable salt
cells
photosensitizing
Prior art date
Application number
NO20040822A
Other languages
English (en)
Norwegian (no)
Other versions
NO20040822L (no
Inventor
Kristian Berg
N N
Diem Tran
Pal Kristian Selbo
Original Assignee
Pci Biotech As
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Publication date
Application filed by Pci Biotech As filed Critical Pci Biotech As
Publication of NO20040822L publication Critical patent/NO20040822L/no
Publication of NO332191B1 publication Critical patent/NO332191B1/no

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/008Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Detergent Compositions (AREA)
NO20040822A 2001-08-30 2004-02-25 Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi NO332191B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0121023.6A GB0121023D0 (en) 2001-08-30 2001-08-30 Compound
PCT/GB2002/003973 WO2003020309A2 (en) 2001-08-30 2002-08-30 Compound

Publications (2)

Publication Number Publication Date
NO20040822L NO20040822L (no) 2004-04-29
NO332191B1 true NO332191B1 (no) 2012-07-23

Family

ID=9921225

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20040822A NO332191B1 (no) 2001-08-30 2004-02-25 Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi

Country Status (20)

Country Link
US (2) US7662807B2 (pt)
EP (1) EP1420824B1 (pt)
JP (1) JP5068920B2 (pt)
KR (1) KR100883927B1 (pt)
CN (1) CN100438909C (pt)
AT (1) ATE327768T1 (pt)
BR (1) BRPI0212172B8 (pt)
CA (1) CA2457856C (pt)
DE (1) DE60211918T2 (pt)
ES (1) ES2265047T3 (pt)
GB (1) GB0121023D0 (pt)
HK (1) HK1060974A1 (pt)
HU (1) HU229623B1 (pt)
MX (1) MXPA04001813A (pt)
NO (1) NO332191B1 (pt)
NZ (1) NZ531598A (pt)
PL (1) PL206900B1 (pt)
PT (1) PT1420824E (pt)
RU (1) RU2323940C2 (pt)
WO (1) WO2003020309A2 (pt)

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GB0415263D0 (en) * 2004-07-07 2004-08-11 Norwegian Radium Hospital Res Method
FR2877943B1 (fr) 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
CN100361994C (zh) * 2004-12-10 2008-01-16 吉林大学 四苯基卟啉衍生物及其在有机电致发光器件中的应用
GB0613753D0 (en) 2006-07-11 2006-08-23 Norwegian Radium Hospital Res Method
CN101153085B (zh) * 2006-09-25 2010-05-12 中国科学院化学研究所 具有可逆手性的超分子手性膜及其制备方法
WO2008102669A1 (ja) * 2007-02-19 2008-08-28 Rei Medical Co., Ltd. 新規な糖連結クロリン誘導体及びその製造方法
GB0811955D0 (en) 2008-06-30 2008-07-30 Pci Biotech As Method
KR100972504B1 (ko) * 2008-07-14 2010-07-26 김현종 휴대가 가능한 접철식 노트북 받침대
EP3459955B1 (en) * 2008-09-18 2022-11-02 biolitec Unternehmensberatungs II AG Novel method and application of unsymmetrically meso-substituted porphyrins and chlorins for pdt
GB0819594D0 (en) * 2008-10-24 2008-12-03 Univ Coimbrra Process
GB0914286D0 (en) * 2009-08-14 2009-09-30 Pci Biotech As Method
GB0914287D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Compositions
CN102260269B (zh) * 2010-05-25 2013-11-06 苏州和健医药科技有限公司 一种含有卟啉或二氢卟吩的树状化合物及其应用
CN102653541B (zh) * 2011-03-04 2014-01-15 国家纳米科学中心 一种卟啉化合物及其制备方法和应用
CN102786526B (zh) * 2011-05-20 2014-07-16 国家纳米科学中心 一种卟啉-酞菁二连体及其制备方法和应用
US8907081B2 (en) 2011-05-27 2014-12-09 Sharp Laboratories Of America, Inc. Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
GB201208548D0 (en) 2012-05-15 2012-06-27 Pci Biotech As Compound and method
CN102952143B (zh) * 2012-11-08 2015-12-02 唐江涛 一种四苯基卟吩的制备方法
US20160040128A1 (en) * 2013-03-15 2016-02-11 Pci Biotech As Method
US10610582B2 (en) 2013-08-28 2020-04-07 Pci Biotech As Compound and method for vaccination and immunisation
WO2015028575A1 (en) * 2013-08-28 2015-03-05 Pci Biotech As Immunisation method by photochemical internalisation
US10537639B2 (en) 2014-08-28 2020-01-21 Pci Biotech As Compound and method
CN104459099B (zh) * 2014-12-18 2016-04-13 东南大学 卟啉衍生物在制备检测炎症相关疾病试剂中的应用
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
CA3040344A1 (en) * 2016-10-14 2018-04-19 Pci Biotech As Treatment of cholangiocarcinoma with tpcs-2a induced photochemical internalisation of gemcitabine
GB201718631D0 (en) 2017-11-10 2017-12-27 Pci Biotech As Method
JP2021531345A (ja) 2018-07-16 2021-11-18 ディーシープライム・ベスローテン・フェンノートシャップDcprime B.V. 腫瘍ワクチン接種に用いるための組合せ製品
US11052144B2 (en) 2019-04-25 2021-07-06 Dcprime B.V. Methods of tumor vaccination
CN112898310A (zh) * 2019-12-03 2021-06-04 中国石油天然气股份有限公司 地质卟啉加氢衍生化方法、所得加氢产物及同位素分析法
AU2021243864A1 (en) 2020-03-27 2022-11-03 Mendus B.V. Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
CA3172447A1 (en) 2020-03-27 2021-09-30 Erik Hans MANTING In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
EP4240405A1 (en) 2020-11-05 2023-09-13 Mendus B.V. Use of tumor-independent antigens in immunotherapies
CA3212351A1 (en) 2021-03-12 2022-09-15 Mendus B.V. Methods of vaccination and use of cd47 blockade

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Publication number Priority date Publication date Assignee Title
HU204856B (en) 1987-08-12 1992-02-28 Orszagos Mueszaki Fejlesztesi Process for releasing cell mixtures and tissues from undesired populations and for producing monoclonal antibody - hematoporphyrin conjugates
JPH05253466A (ja) * 1992-03-12 1993-10-05 Res Dev Corp Of Japan 磁気異方性薄膜の製造方法
NO180167C (no) * 1994-09-08 1997-02-26 Photocure As Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol
GB9700396D0 (en) 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
JP2000007693A (ja) * 1998-06-26 2000-01-11 Lederle Japan Ltd クロリン誘導体
GB9905911D0 (en) 1999-03-15 1999-05-05 Photocure As Method
AU4139600A (en) * 1999-04-14 2000-11-14 University Of British Columbia, The 1,3-dipolar cycloadditions to polypyrrolic macrocycles

Also Published As

Publication number Publication date
BRPI0212172B1 (pt) 2019-03-06
RU2323940C2 (ru) 2008-05-10
DE60211918T2 (de) 2007-01-18
ATE327768T1 (de) 2006-06-15
BRPI0212172A8 (pt) 2018-12-18
KR100883927B1 (ko) 2009-02-18
RU2004109228A (ru) 2005-04-10
CN100438909C (zh) 2008-12-03
WO2003020309A3 (en) 2003-10-30
GB0121023D0 (en) 2001-10-24
PL206900B1 (pl) 2010-10-29
HK1060974A1 (en) 2004-09-03
KR20040032983A (ko) 2004-04-17
MXPA04001813A (es) 2005-03-07
US20100121255A1 (en) 2010-05-13
CA2457856A1 (en) 2003-03-13
CN1549729A (zh) 2004-11-24
WO2003020309A2 (en) 2003-03-13
PL369289A1 (en) 2005-04-18
EP1420824B1 (en) 2006-05-31
EP1420824A2 (en) 2004-05-26
JP5068920B2 (ja) 2012-11-07
CA2457856C (en) 2011-01-25
HU229623B1 (en) 2014-03-28
BRPI0212172B8 (pt) 2021-05-25
HUP0401434A2 (hu) 2004-12-28
BR0212172A (pt) 2004-07-20
ES2265047T3 (es) 2007-02-01
AU2002313562B2 (en) 2006-09-07
US7662807B2 (en) 2010-02-16
US8096419B2 (en) 2012-01-17
PT1420824E (pt) 2006-08-31
JP2005507383A (ja) 2005-03-17
NZ531598A (en) 2005-09-30
DE60211918D1 (en) 2006-07-06
HUP0401434A3 (en) 2008-05-28
US20060052433A1 (en) 2006-03-09
NO20040822L (no) 2004-04-29

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