NO331734B1 - Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. - Google Patents
Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. Download PDFInfo
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- NO331734B1 NO331734B1 NO20011308A NO20011308A NO331734B1 NO 331734 B1 NO331734 B1 NO 331734B1 NO 20011308 A NO20011308 A NO 20011308A NO 20011308 A NO20011308 A NO 20011308A NO 331734 B1 NO331734 B1 NO 331734B1
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- Prior art keywords
- acid
- acceptable salts
- physiologically acceptable
- nme
- cyclo
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19842415A DE19842415A1 (de) | 1998-09-16 | 1998-09-16 | Pharmazeutische Zubereitung |
| PCT/EP1999/006654 WO2000015244A2 (de) | 1998-09-16 | 1999-09-09 | Pharmazeutische zubereitung enthaltend ein cyclo-peptide und ein chemotherapeutikum oder einen angiogeneseinhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20011308D0 NO20011308D0 (no) | 2001-03-15 |
| NO20011308L NO20011308L (no) | 2001-03-15 |
| NO331734B1 true NO331734B1 (no) | 2012-03-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20011308A NO331734B1 (no) | 1998-09-16 | 2001-03-15 | Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6683051B1 (cs) |
| EP (2) | EP1466615B1 (cs) |
| JP (2) | JP2002524526A (cs) |
| KR (1) | KR100703253B1 (cs) |
| CN (2) | CN1201812C (cs) |
| AR (2) | AR022382A1 (cs) |
| AT (2) | ATE292470T1 (cs) |
| AU (1) | AU765073B2 (cs) |
| BR (1) | BR9913737A (cs) |
| CA (1) | CA2344151A1 (cs) |
| CO (1) | CO5140070A1 (cs) |
| CZ (1) | CZ302908B6 (cs) |
| DE (3) | DE19842415A1 (cs) |
| DK (2) | DK1113809T3 (cs) |
| ES (2) | ES2327331T3 (cs) |
| HU (1) | HUP0103521A3 (cs) |
| ID (1) | ID29226A (cs) |
| IL (2) | IL141516A0 (cs) |
| MY (1) | MY129572A (cs) |
| NO (1) | NO331734B1 (cs) |
| NZ (1) | NZ510040A (cs) |
| PE (1) | PE20001046A1 (cs) |
| PL (1) | PL201902B1 (cs) |
| PT (2) | PT1113809E (cs) |
| RU (1) | RU2227041C2 (cs) |
| SI (1) | SI1113809T1 (cs) |
| SK (1) | SK287012B6 (cs) |
| TR (1) | TR200100765T2 (cs) |
| TW (1) | TW576744B (cs) |
| WO (1) | WO2000015244A2 (cs) |
| ZA (1) | ZA200103073B (cs) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7740841B1 (en) * | 2000-01-28 | 2010-06-22 | Sunnybrook Health Science Center | Therapeutic method for reducing angiogenesis |
| KR100983997B1 (ko) * | 2001-01-09 | 2010-09-28 | 메르크 파텐트 게엠베하 | 수용체 타이로신 키나아제 저해제 및 혈관형성 저해제를 사용하는 병용 요법 |
| AU2003211594A1 (en) * | 2002-03-05 | 2003-09-16 | Eisai Co., Ltd. | Antitumor agent comprising combination of sulfonamide-containing heterocyclic compound with angiogenesis inhibitor |
| JP5223072B2 (ja) | 2004-04-02 | 2013-06-26 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ａｖβ５インテグリンに関連のある疾患を治療および予防するための方法および組成物 |
| NZ567837A (en) * | 2005-11-02 | 2011-11-25 | Univ Texas | Concurrent chemotherapy and immunotherapy with EGFRvIII peptide and temozolomide |
| WO2007084670A2 (en) * | 2006-01-18 | 2007-07-26 | Merck Patent Gmbh | Specific therapy using integrin ligands for treating cancer |
| US20110165150A1 (en) * | 2006-01-18 | 2011-07-07 | Merck Patent Gmbh | Isolated organ perfusion combination therapy of cancer |
| DK2101805T3 (da) | 2007-01-18 | 2013-01-21 | Merck Patent Gmbh | Integrinligander til anvendelse i behandling af cancer |
| PL2167128T3 (pl) | 2007-07-17 | 2013-03-29 | Merck Patent Gmbh | Skonstruowane metodami inżynierii hybrydowe przeciwciała skierowane przeciwko integrynie alfa-v |
| WO2010051667A1 (zh) * | 2008-11-10 | 2010-05-14 | 复旦大学 | 一种环肽纳米管药物组合物及其应用 |
| WO2010057596A2 (en) * | 2008-11-20 | 2010-05-27 | Merck Patent Gmbh | New therapy and medicament using integrin ligands for treating cancer |
| US20120130146A1 (en) | 2009-05-25 | 2012-05-24 | Merck Patent Gmbh | Continuous administration of cilengitide in cancer treatments |
| EP2456460A4 (en) | 2009-07-24 | 2013-02-20 | Univ California | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING INEGRINE V ASSOCIATED DISEASES |
| EA022700B1 (ru) | 2009-12-10 | 2016-02-29 | Мерк Патент Гмбх | Фармацевтическая композиция, содержащая олигопептиды |
| CN103153328A (zh) | 2010-07-16 | 2013-06-12 | 默克专利股份有限公司 | 肽在乳腺癌和/或骨转移灶的治疗中的用途 |
| WO2012069149A1 (en) | 2010-11-23 | 2012-05-31 | Merck Patent Gmbh | Solution comprising cyclic oligopeptides |
| SI2672994T1 (sl) | 2011-02-11 | 2018-09-28 | Merck Patent Gmbh | Protitelo proti alfa-v integrinu za zdravljenje raka prostate |
| WO2012110200A1 (en) * | 2011-02-18 | 2012-08-23 | Merck Patent Gmbh | Cyclic peptide cyclo (l -arginyl - glycyl - l -aspartyl - d - phenylalanyl - n-methyl - l -valyl), compositions thereof, and use thereof in methods for treating graft -versus - host disease |
| JP2014516996A (ja) * | 2011-06-09 | 2014-07-17 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | キャリア中のシレンギチドの懸濁液による癌および転移の処置 |
| US20130230485A1 (en) * | 2012-03-01 | 2013-09-05 | Kathleen E. Rodgers | Methods for Treating Patients Undergoing Multi-Cycle Chemotherapy |
| CN103333227B (zh) * | 2013-06-07 | 2015-10-07 | 东南大学 | 转移肿瘤缺失蛋白小分子环肽抑制剂及其制备方法与应用 |
| EP3510407A1 (en) | 2016-09-08 | 2019-07-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing and treating nephrotic syndrome |
| JP2019208422A (ja) * | 2018-06-04 | 2019-12-12 | コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー | ヒアルロニダーゼを含む新規な組換えエキソソーム及びその用途 |
| GB201911816D0 (en) * | 2019-08-16 | 2019-10-02 | Univ London Queen Mary | Treatment |
| GB202103122D0 (en) * | 2021-03-05 | 2021-04-21 | Univ London Queen Mary | Treatment |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH04367367A (ja) | 1991-06-11 | 1992-12-18 | Nkk Corp | ロータリノズル |
| CA2144762A1 (en) | 1992-10-14 | 1994-04-28 | George D. Hartman | Fibrinogen receptor antagonists |
| EP0673247A4 (en) | 1992-12-01 | 1996-05-01 | Merck & Co Inc | FIBRINOGEN RECEPTOR ANTAGONISTS. |
| WO1995032710A1 (en) | 1994-05-27 | 1995-12-07 | Merck & Co., Inc. | Compounds for inhibiting osteoclast-mediated bone resorption |
| JPH10504808A (ja) | 1994-06-29 | 1998-05-12 | スミスクライン・ビーチャム・コーポレイション | ビトロネクチン受容体拮抗物質 |
| JPH10504807A (ja) | 1994-06-29 | 1998-05-12 | スミスクライン・ビーチャム・コーポレイション | ビトロネクチン受容体拮抗剤 |
| DK0710657T3 (da) | 1994-11-02 | 1999-05-25 | Merck Patent Gmbh | Adhæsionsreceptor-antagonister |
| DE19534177A1 (de) * | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| DE19548709A1 (de) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosinderivate |
| JPH09208571A (ja) * | 1996-02-02 | 1997-08-12 | Takeda Chem Ind Ltd | アルキリデンシクロヘキサン誘導体 |
| AU2438297A (en) * | 1996-05-09 | 1997-11-26 | Alcon Laboratories, Inc. | Combinations of angiostatic compounds |
| US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
| DK0951295T3 (da) * | 1996-05-31 | 2010-09-13 | Scripps Research Inst | Sammensætninger til anvendelse ved inhibering af alfa-v-beta3-medieret angiogenese |
| JPH1081631A (ja) * | 1996-07-17 | 1998-03-31 | Takeda Chem Ind Ltd | 癌転移または再発抑制剤 |
| DE19629817A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| DE19629816A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Cycloalkyl-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| UA60311C2 (uk) * | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
| EP1007026A4 (en) * | 1997-01-17 | 2002-08-07 | Merck & Co Inc | INTEGRIN ANTAGONISTS |
| DE19850131A1 (de) | 1998-10-30 | 2000-05-04 | Merck Patent Gmbh | Chromenon- und Chromanonderivate |
-
1998
- 1998-09-16 DE DE19842415A patent/DE19842415A1/de not_active Withdrawn
-
1999
- 1999-09-09 US US09/787,374 patent/US6683051B1/en not_active Expired - Lifetime
- 1999-09-09 BR BR9913737-2A patent/BR9913737A/pt not_active Application Discontinuation
- 1999-09-09 ID IDW20010746A patent/ID29226A/id unknown
- 1999-09-09 NZ NZ510040A patent/NZ510040A/en not_active IP Right Cessation
- 1999-09-09 IL IL14151699A patent/IL141516A0/xx unknown
- 1999-09-09 RU RU2001110104/15A patent/RU2227041C2/ru not_active IP Right Cessation
- 1999-09-09 ES ES04006076T patent/ES2327331T3/es not_active Expired - Lifetime
- 1999-09-09 DE DE59911881T patent/DE59911881D1/de not_active Expired - Lifetime
- 1999-09-09 DK DK99969031T patent/DK1113809T3/da active
- 1999-09-09 PT PT99969031T patent/PT1113809E/pt unknown
- 1999-09-09 HU HU0103521A patent/HUP0103521A3/hu unknown
- 1999-09-09 CN CNB998133876A patent/CN1201812C/zh not_active Expired - Fee Related
- 1999-09-09 EP EP04006076A patent/EP1466615B1/de not_active Expired - Lifetime
- 1999-09-09 WO PCT/EP1999/006654 patent/WO2000015244A2/de active IP Right Grant
- 1999-09-09 KR KR1020017003238A patent/KR100703253B1/ko not_active IP Right Cessation
- 1999-09-09 CN CNB2004100834955A patent/CN100352494C/zh not_active Expired - Fee Related
- 1999-09-09 AT AT99969031T patent/ATE292470T1/de active
- 1999-09-09 SK SK337-2001A patent/SK287012B6/sk not_active IP Right Cessation
- 1999-09-09 EP EP99969031A patent/EP1113809B1/de not_active Expired - Lifetime
- 1999-09-09 DK DK04006076T patent/DK1466615T3/da active
- 1999-09-09 AT AT04006076T patent/ATE432707T1/de active
- 1999-09-09 PL PL348026A patent/PL201902B1/pl not_active IP Right Cessation
- 1999-09-09 SI SI9930792T patent/SI1113809T1/xx unknown
- 1999-09-09 TR TR2001/00765T patent/TR200100765T2/xx unknown
- 1999-09-09 PT PT04006076T patent/PT1466615E/pt unknown
- 1999-09-09 CA CA002344151A patent/CA2344151A1/en not_active Abandoned
- 1999-09-09 ES ES99969031T patent/ES2241363T3/es not_active Expired - Lifetime
- 1999-09-09 DE DE59915033T patent/DE59915033D1/de not_active Expired - Lifetime
- 1999-09-09 JP JP2000569828A patent/JP2002524526A/ja active Pending
- 1999-09-09 AU AU59758/99A patent/AU765073B2/en not_active Ceased
- 1999-09-09 CZ CZ20010932A patent/CZ302908B6/cs not_active IP Right Cessation
- 1999-09-13 PE PE1999000926A patent/PE20001046A1/es not_active Application Discontinuation
- 1999-09-13 MY MYPI99003955A patent/MY129572A/en unknown
- 1999-09-15 AR ARP990104617A patent/AR022382A1/es not_active Application Discontinuation
- 1999-09-16 TW TW088116003A patent/TW576744B/zh not_active IP Right Cessation
- 1999-09-16 CO CO99058733A patent/CO5140070A1/es unknown
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2001
- 2001-02-19 IL IL141516A patent/IL141516A/en not_active IP Right Cessation
- 2001-03-15 NO NO20011308A patent/NO331734B1/no not_active IP Right Cessation
- 2001-04-12 ZA ZA200103073A patent/ZA200103073B/en unknown
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2010
- 2010-09-15 AR ARP100103356A patent/AR078175A2/es not_active Application Discontinuation
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2011
- 2011-08-12 JP JP2011176480A patent/JP2011252012A/ja active Pending
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