NO325518B1 - Nye fettsyrederivater - Google Patents

Nye fettsyrederivater Download PDF

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Publication number
NO325518B1
NO325518B1 NO19993563A NO993563A NO325518B1 NO 325518 B1 NO325518 B1 NO 325518B1 NO 19993563 A NO19993563 A NO 19993563A NO 993563 A NO993563 A NO 993563A NO 325518 B1 NO325518 B1 NO 325518B1
Authority
NO
Norway
Prior art keywords
lipophilic
acid
compound
cis
derivative according
Prior art date
Application number
NO19993563A
Other languages
English (en)
Norwegian (no)
Other versions
NO993563D0 (no
NO993563L (no
Inventor
Bernt Borretzen
Are Dalen
Finn Myhren
Marit Liland Sandvold
Original Assignee
Conpharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conpharma As filed Critical Conpharma As
Publication of NO993563D0 publication Critical patent/NO993563D0/no
Publication of NO993563L publication Critical patent/NO993563L/no
Publication of NO325518B1 publication Critical patent/NO325518B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03Monocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C07C69/72Acetoacetic acid esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO19993563A 1997-01-24 1999-07-21 Nye fettsyrederivater NO325518B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9701441A GB2321455A (en) 1997-01-24 1997-01-24 Lipophilic derivatives of biologically active compounds
PCT/NO1998/000021 WO1998032718A1 (en) 1997-01-24 1998-01-23 New fatty acid derivatives

Publications (3)

Publication Number Publication Date
NO993563D0 NO993563D0 (no) 1999-07-21
NO993563L NO993563L (no) 1999-09-17
NO325518B1 true NO325518B1 (no) 2008-06-02

Family

ID=10806515

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993563A NO325518B1 (no) 1997-01-24 1999-07-21 Nye fettsyrederivater

Country Status (23)

Country Link
US (3) US20010006962A1 (cs)
EP (1) EP0977725B1 (cs)
JP (2) JP4698773B2 (cs)
KR (1) KR100546457B1 (cs)
AT (1) ATE269292T1 (cs)
AU (1) AU733370B2 (cs)
CA (1) CA2276694C (cs)
CZ (1) CZ299815B6 (cs)
DE (1) DE69824574T2 (cs)
DK (1) DK0977725T3 (cs)
ES (1) ES2224356T3 (cs)
GB (1) GB2321455A (cs)
HU (1) HU225664B1 (cs)
IL (1) IL130853A (cs)
NO (1) NO325518B1 (cs)
NZ (1) NZ336724A (cs)
PL (1) PL196831B1 (cs)
RU (1) RU2227794C2 (cs)
SK (1) SK284803B6 (cs)
TW (1) TWI231209B (cs)
UA (1) UA65557C2 (cs)
WO (1) WO1998032718A1 (cs)
ZA (1) ZA98579B (cs)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6576636B2 (en) * 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US6207700B1 (en) * 1999-01-07 2001-03-27 Vanderbilt University Amide derivatives for antiangiogenic and/or antitumorigenic use
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
AU2002305099A1 (en) * 2001-03-23 2002-10-08 Protarga, Inc. Fatty alcohol drug conjugates
AU2002303164A1 (en) 2001-03-23 2002-10-08 Protarga, Inc. Fatty amine drug conjugates
NZ537716A (en) * 2002-07-08 2007-05-31 Glaxosmithkline Zagreb Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use
RS20050008A (en) * 2002-07-08 2007-06-04 Pliva-Istraživački Institut D.O.O., New compounds,compositions and methods for treatment of inflammatory diseases and conditions
CN1665831A (zh) * 2002-07-08 2005-09-07 普利瓦研究院有限公司 作为甾类/非甾类抗炎、抗肿瘤和抗病毒活性分子载体的新化合物、组合物
US20040235811A1 (en) 2002-10-08 2004-11-25 Sepracor Inc. Fatty acid modified forms of glucocorticoids
US7196082B2 (en) * 2002-11-08 2007-03-27 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
GB0304927D0 (en) 2003-03-04 2003-04-09 Resolution Chemicals Ltd Process for the production of tibolone
CA2562783A1 (en) 2004-04-26 2005-12-01 Vanderbilt University Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity
NO324263B1 (no) 2005-12-08 2007-09-17 Clavis Pharma Asa Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
US8497292B2 (en) * 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
EP2040699A4 (en) 2006-06-19 2013-03-13 Vanderbilt University Medical Ct METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND THERAPEUTIC TARGETING OF COX-2
NO331891B1 (no) * 2007-03-20 2012-04-30 Clavis Pharma Asa Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS
MX2010003002A (es) * 2007-09-26 2010-07-05 Sinai School Medicine Analogos de azacitidina y sus usos.
WO2010028458A1 (en) * 2008-09-12 2010-03-18 Parnell Laboratories (Aust) Pty Ltd Prodrugs of isoxazolyl penicillins and uses thereof
KR101759360B1 (ko) * 2009-08-26 2017-07-18 바스프 에스이 항미생물성 아미노-살리실산 유도체
WO2012174121A2 (en) * 2011-06-13 2012-12-20 The University Of Kansas Decoquinate prodrugs
EP3078374B1 (en) 2011-10-17 2019-06-19 Vanderbilt University Indomethacin analogs for the treatment of castrate-resistant prostate cancer
BR112014026535A2 (pt) 2012-04-27 2017-06-27 Nagoya Industrial Science Res Institute derivado de ácido trans-2-decenoico e fármaco contendo o mesmo
CN103450141B (zh) * 2013-08-23 2015-08-26 山东鲁抗舍里乐药业有限公司 一种苯并吡喃酮类化合物、其制备方法及其应用
CA3056810A1 (en) 2017-04-21 2018-10-25 University Of Tasmania Therapeutic compounds and methods
CN111116374B (zh) * 2019-12-04 2020-12-15 北京理工大学 一种氨鲁米特与2-硝基苯甲酸合成π-π键共晶体的方法
JP7231576B2 (ja) 2020-03-09 2023-03-01 株式会社日立ハイテク 電解質濃度測定装置

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2933380A (en) * 1955-06-22 1960-04-19 Du Pont Motor fuels
GB1269942A (en) * 1968-07-25 1972-04-06 Murphy Chemical Ltd Improvements in or relating to pesticides
GB1325797A (en) * 1970-09-24 1973-08-08 Upjohn Co Medicines comprising cytidine derivatives
IT1043956B (it) 1970-10-17 1980-02-29 Isf Spa 21 esteri di acidi grassi insaturi del desa e beta metazone
JPS4882023A (cs) * 1972-02-04 1973-11-02
JPS50129584A (cs) * 1974-03-25 1975-10-13
CA1113486A (en) * 1977-04-01 1981-12-01 Alfred Halpern Ultra-violet filtration with certain aminosalicylic acid esters
FR2485001A1 (fr) * 1980-06-02 1981-12-24 Svatos Antonin Esters de l'acide ricinoleique et de chloroxylenols et compositions antiparasitaires
US4436726A (en) * 1980-12-15 1984-03-13 Fujisawa Pharmaceutical Co., Ltd. N-Acylpeptide compound, processes for the preparation thereof and the pharmaceutical compositions
US4554279A (en) * 1981-01-29 1985-11-19 The United States Of America As Represented By The Secretary Of The Army 5-(Straight chain 3-12 carbon alkoxy)-8-quinolinamines and their use for treatment of malaria
EP0105404A1 (en) * 1982-09-30 1984-04-18 Merck & Co. Inc. Derivatives of steroid compounds linked to cyotoxic agents and process for their preparation
US4551279A (en) * 1984-01-09 1985-11-05 G. D. Searle & Co. Protease inhibitors
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
JPS61204197A (ja) * 1985-03-06 1986-09-10 Yoshikawa Seiyu Kk ステロ−ル脂肪酸エステルの製造方法
ZA852614B (en) * 1985-05-17 1986-10-09 Takeda Chemical Industries, Ltd. Ascorbic acid ethers and their production
GB2178031B (en) * 1985-06-10 1989-07-26 Procter & Gamble Phenylacetic acid amides having anti-inflammatory and analgesic activity
US4722927A (en) * 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
DE3625738A1 (de) * 1986-07-30 1988-02-11 Goedecke Ag 2-acyloxypropylamin-derivate, verfahren zu deren herstellung und deren verwendung
ES2061624T3 (es) * 1987-03-09 1994-12-16 Procter & Gamble Compuestos fenilicos sustituidos con amino-etilo en posicion beta, y composiciones anti-inflamatorias o analgesicas que los contienen.
JPH0196158A (ja) * 1987-10-09 1989-04-14 Santen Pharmaceut Co Ltd 抗炎症剤
US5284876A (en) * 1988-02-26 1994-02-08 Neuromedica, Inc. Method of treating tardive dyskinesia using dopaminergic agents of prodrugs of therapeutic agents
DE3826846A1 (de) * 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
US5135736A (en) * 1988-08-15 1992-08-04 Neorx Corporation Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
JPH02212488A (ja) * 1989-02-13 1990-08-23 Shinichiro Shimizu トリアゾールピリミジン誘導体
JPH0381286A (ja) * 1989-08-22 1991-04-05 Green Cross Corp:The ステロイド外用剤
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
FR2664500B1 (fr) * 1990-07-13 1994-10-28 Lille Ii Universite Droit Sant Procede de preparation d'une lipoproteine modifiee par incorporation d'une substance active lipophile, lipoproteine modifiee ainsi obtenue et composition pharmaceutique ou cosmetique la contenant.
EP0543919B1 (en) * 1990-08-13 1996-04-10 G.D. Searle & Co. Use of heterocyclic amino-alcohol compounds in the manufacture of a medicament for treatment of cns diseases
US5242945A (en) * 1991-04-12 1993-09-07 American Home Products Corporation Tetronic and thiotetronic acid derivatives as phospholipase a2 inhibitors
GB2260319B (en) * 1991-10-07 1995-12-06 Norsk Hydro As Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
US5238933A (en) * 1991-10-28 1993-08-24 Sri International Skin permeation enhancer compositions
WO1993020800A1 (en) * 1992-04-08 1993-10-28 Paavo Kai Johannes Kinnunen Composition for therapeutic or diagnostic use, process for its preparation and its use
US5324747A (en) * 1992-07-15 1994-06-28 Hoffmann-La Roche Inc. N-substituted anilines, inhibitors of phospholipases A2
US5807884A (en) * 1992-10-30 1998-09-15 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
US5466685A (en) * 1993-05-13 1995-11-14 Johnson & Johnson Inhibition of expression of beta-lactamase using esters of fatty acid alcohols
CA2185803C (en) * 1994-03-18 2006-07-11 Edward M. Rudnic Emulsified drug delivery systems
US5447729A (en) * 1994-04-07 1995-09-05 Pharmavene, Inc. Multilamellar drug delivery systems
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
JPH08217787A (ja) * 1995-02-15 1996-08-27 Meiji Seika Kaisha Ltd 脂溶性アントラサイクリン誘導体
JPH08325154A (ja) * 1995-03-31 1996-12-10 Mitsui Toatsu Chem Inc 安息香酸誘導体およびそれを有効成分として含有するホスホリパーゼa2阻害剤
PT771817E (pt) * 1995-10-30 2003-06-30 Oleoyl Estrone Developments S Mono-esteres de oleato de estrogenos para o tratamento da obesidade e/ou excesso de peso

Also Published As

Publication number Publication date
NZ336724A (en) 2001-06-29
US20010006962A1 (en) 2001-07-05
US20030153544A1 (en) 2003-08-14
ZA98579B (en) 1998-07-23
JP2009280583A (ja) 2009-12-03
AU5782898A (en) 1998-08-18
EP0977725A1 (en) 2000-02-09
TWI231209B (en) 2005-04-21
NO993563D0 (no) 1999-07-21
JP5232083B2 (ja) 2013-07-10
SK284803B6 (sk) 2005-11-03
PL196831B1 (pl) 2008-02-29
CZ247799A3 (cs) 2000-02-16
GB9701441D0 (en) 1997-03-12
ES2224356T3 (es) 2005-03-01
UA65557C2 (uk) 2004-04-15
DK0977725T3 (da) 2004-09-13
HUP0000937A2 (hu) 2000-09-28
EP0977725B1 (en) 2004-06-16
NO993563L (no) 1999-09-17
JP4698773B2 (ja) 2011-06-08
CA2276694A1 (en) 1998-07-30
DE69824574D1 (de) 2004-07-22
ATE269292T1 (de) 2004-07-15
PL334919A1 (en) 2000-03-27
HU225664B1 (en) 2007-05-29
KR20000070317A (ko) 2000-11-25
AU733370B2 (en) 2001-05-10
KR100546457B1 (ko) 2006-01-26
US6762175B2 (en) 2004-07-13
RU2227794C2 (ru) 2004-04-27
SK100399A3 (en) 2000-01-18
DE69824574T2 (de) 2005-07-14
US20040063677A1 (en) 2004-04-01
CZ299815B6 (cs) 2008-12-03
HUP0000937A3 (en) 2001-01-29
WO1998032718A1 (en) 1998-07-30
IL130853A (en) 2005-03-20
JP2001522351A (ja) 2001-11-13
CA2276694C (en) 2007-05-22
GB2321455A (en) 1998-07-29
IL130853A0 (en) 2001-01-28

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