IL130853A - Fatty acid derivatives - Google Patents

Fatty acid derivatives

Info

Publication number
IL130853A
IL130853A IL13085398A IL13085398A IL130853A IL 130853 A IL130853 A IL 130853A IL 13085398 A IL13085398 A IL 13085398A IL 13085398 A IL13085398 A IL 13085398A IL 130853 A IL130853 A IL 130853A
Authority
IL
Israel
Prior art keywords
nonadecenyl
heptadecenyl
rch
cis
trans
Prior art date
Application number
IL13085398A
Other languages
English (en)
Other versions
IL130853A0 (en
Original Assignee
Conpharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conpharma As filed Critical Conpharma As
Publication of IL130853A0 publication Critical patent/IL130853A0/xx
Publication of IL130853A publication Critical patent/IL130853A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C07C69/72—Acetoacetic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
IL13085398A 1997-01-24 1998-01-23 Fatty acid derivatives IL130853A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9701441A GB2321455A (en) 1997-01-24 1997-01-24 Lipophilic derivatives of biologically active compounds
PCT/NO1998/000021 WO1998032718A1 (en) 1997-01-24 1998-01-23 New fatty acid derivatives

Publications (2)

Publication Number Publication Date
IL130853A0 IL130853A0 (en) 2001-01-28
IL130853A true IL130853A (en) 2005-03-20

Family

ID=10806515

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13085398A IL130853A (en) 1997-01-24 1998-01-23 Fatty acid derivatives

Country Status (23)

Country Link
US (3) US20010006962A1 (xx)
EP (1) EP0977725B1 (xx)
JP (2) JP4698773B2 (xx)
KR (1) KR100546457B1 (xx)
AT (1) ATE269292T1 (xx)
AU (1) AU733370B2 (xx)
CA (1) CA2276694C (xx)
CZ (1) CZ299815B6 (xx)
DE (1) DE69824574T2 (xx)
DK (1) DK0977725T3 (xx)
ES (1) ES2224356T3 (xx)
GB (1) GB2321455A (xx)
HU (1) HU225664B1 (xx)
IL (1) IL130853A (xx)
NO (1) NO325518B1 (xx)
NZ (1) NZ336724A (xx)
PL (1) PL196831B1 (xx)
RU (1) RU2227794C2 (xx)
SK (1) SK284803B6 (xx)
TW (1) TWI231209B (xx)
UA (1) UA65557C2 (xx)
WO (1) WO1998032718A1 (xx)
ZA (1) ZA98579B (xx)

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US6207700B1 (en) * 1999-01-07 2001-03-27 Vanderbilt University Amide derivatives for antiangiogenic and/or antitumorigenic use
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
US7816398B2 (en) * 2001-03-23 2010-10-19 Luitpold Pharmaceuticals, Inc. Fatty alcohol drug conjugates
JP2005500988A (ja) * 2001-03-23 2005-01-13 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪族アミン薬物複合体
AU2003255851B2 (en) * 2002-07-08 2009-07-23 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. New compounds, compositions and methods for treatment of inflammatory diseases and conditions
AU2003255849A1 (en) * 2002-07-08 2004-01-23 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use
ATE429441T1 (de) * 2002-07-08 2009-05-15 Glaxosmithkline Zagreb Hybridmoleküle von makroliden mit steroidalen/nicht-steroidalen antientzündlich aktiven molekülen
WO2004033478A2 (en) 2002-10-08 2004-04-22 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
US7196082B2 (en) * 2002-11-08 2007-03-27 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
GB0304927D0 (en) 2003-03-04 2003-04-09 Resolution Chemicals Ltd Process for the production of tibolone
JP2007534702A (ja) 2004-04-26 2007-11-29 バンダービルト・ユニバーシティ 胃腸毒性の低い治療薬としてのインドール酢酸、及びインデン酢酸誘導体
NO324263B1 (no) 2005-12-08 2007-09-17 Clavis Pharma Asa Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
US8497292B2 (en) 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
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NO331891B1 (no) 2007-03-20 2012-04-30 Clavis Pharma Asa Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS
MX2010003261A (es) 2007-09-26 2010-08-18 Sinai School Medicine Analogos de azacitidina y usos de los mismos.
WO2010028458A1 (en) * 2008-09-12 2010-03-18 Parnell Laboratories (Aust) Pty Ltd Prodrugs of isoxazolyl penicillins and uses thereof
WO2011023573A1 (en) * 2009-08-26 2011-03-03 Basf Se Antimicrobial amino-salicylic acid derivatives
US20130150330A1 (en) * 2011-06-13 2013-06-13 University Of Kansas Decoquinate prodrugs
WO2013059245A1 (en) 2011-10-17 2013-04-25 Vanderbilt University Indomethacin analogs for the treatment of castrate-resistant prostate cancer
US9428477B2 (en) 2012-04-27 2016-08-30 Nippon Zoki Pharmaceutical Co., Ltd. Trans-2-decenoic acid derivative and drug containing same
CN103450141B (zh) * 2013-08-23 2015-08-26 山东鲁抗舍里乐药业有限公司 一种苯并吡喃酮类化合物、其制备方法及其应用
CN110582480B (zh) 2017-04-21 2023-11-10 塔斯马尼亚大学 治疗化合物和方法
CN111116374B (zh) * 2019-12-04 2020-12-15 北京理工大学 一种氨鲁米特与2-硝基苯甲酸合成π-π键共晶体的方法
JP7231576B2 (ja) 2020-03-09 2023-03-01 株式会社日立ハイテク 電解質濃度測定装置

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Also Published As

Publication number Publication date
HUP0000937A2 (hu) 2000-09-28
EP0977725B1 (en) 2004-06-16
KR100546457B1 (ko) 2006-01-26
CA2276694C (en) 2007-05-22
JP5232083B2 (ja) 2013-07-10
SK284803B6 (sk) 2005-11-03
CZ299815B6 (cs) 2008-12-03
DK0977725T3 (da) 2004-09-13
US20010006962A1 (en) 2001-07-05
UA65557C2 (uk) 2004-04-15
NO993563L (no) 1999-09-17
PL334919A1 (en) 2000-03-27
AU733370B2 (en) 2001-05-10
ZA98579B (en) 1998-07-23
PL196831B1 (pl) 2008-02-29
CA2276694A1 (en) 1998-07-30
SK100399A3 (en) 2000-01-18
AU5782898A (en) 1998-08-18
DE69824574T2 (de) 2005-07-14
WO1998032718A1 (en) 1998-07-30
GB9701441D0 (en) 1997-03-12
JP4698773B2 (ja) 2011-06-08
US6762175B2 (en) 2004-07-13
US20030153544A1 (en) 2003-08-14
HU225664B1 (en) 2007-05-29
DE69824574D1 (de) 2004-07-22
JP2001522351A (ja) 2001-11-13
JP2009280583A (ja) 2009-12-03
KR20000070317A (ko) 2000-11-25
NZ336724A (en) 2001-06-29
RU2227794C2 (ru) 2004-04-27
US20040063677A1 (en) 2004-04-01
ES2224356T3 (es) 2005-03-01
ATE269292T1 (de) 2004-07-15
NO993563D0 (no) 1999-07-21
TWI231209B (en) 2005-04-21
IL130853A0 (en) 2001-01-28
HUP0000937A3 (en) 2001-01-29
NO325518B1 (no) 2008-06-02
EP0977725A1 (en) 2000-02-09
CZ247799A3 (cs) 2000-02-16
GB2321455A (en) 1998-07-29

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