NO321140B1 - Anvendelse av hydroksylaminderivater som oker den molekylaere chaperonproduksjon, for fremstilling av farmasoytiske preparater, samt nye slike hydroksylaminderivater og farmasoytiske preparater som inneholder de nye hydroksylaminderivater. - Google Patents

Anvendelse av hydroksylaminderivater som oker den molekylaere chaperonproduksjon, for fremstilling av farmasoytiske preparater, samt nye slike hydroksylaminderivater og farmasoytiske preparater som inneholder de nye hydroksylaminderivater. Download PDF

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Publication number
NO321140B1
NO321140B1 NO19973059A NO973059A NO321140B1 NO 321140 B1 NO321140 B1 NO 321140B1 NO 19973059 A NO19973059 A NO 19973059A NO 973059 A NO973059 A NO 973059A NO 321140 B1 NO321140 B1 NO 321140B1
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alkyl
substituted
group
unsubstituted
membered
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NO19973059A
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English (en)
Norwegian (no)
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NO973059L (no
NO973059D0 (no
Inventor
Gyorgy Dorman
Laszlo Jaszlits
Maria Kuerthy
Peter Literati Nagy
Ede Marvanyos
Mihaly Barabas
Laszlo Uerogdi
Katalin Biro
Andrea Jednakovits
Laszlo Vigh
Erzsebet Hegedues
Laszlo Koranyi
Jeno Szulbereky
Gabor Balogh
Ibolya Horvath
Zsolt Torok
Eva Udvardy
Denes Medzihradszky
Bea Mezes
Eszter Kovacs
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Hufarkas Beatrix
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Application filed by Hufarkas Beatrix filed Critical Hufarkas Beatrix
Publication of NO973059D0 publication Critical patent/NO973059D0/no
Publication of NO973059L publication Critical patent/NO973059L/no
Publication of NO321140B1 publication Critical patent/NO321140B1/no

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07C259/02—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by halogen atoms
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    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
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    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
NO19973059A 1995-11-02 1997-07-01 Anvendelse av hydroksylaminderivater som oker den molekylaere chaperonproduksjon, for fremstilling av farmasoytiske preparater, samt nye slike hydroksylaminderivater og farmasoytiske preparater som inneholder de nye hydroksylaminderivater. NO321140B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HU9503141A HU222994B1 (hu) 1995-11-02 1995-11-02 Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására
HU9603919 1996-02-09
HU9629820 1996-10-04
PCT/HU1996/000064 WO1997016439A1 (fr) 1995-11-02 1996-11-01 Derives d'hydroxylamine utilises pour ameliorer la production de chaperons moleculaires et leur preparation

Publications (3)

Publication Number Publication Date
NO973059D0 NO973059D0 (no) 1997-07-01
NO973059L NO973059L (no) 1997-09-02
NO321140B1 true NO321140B1 (no) 2006-03-27

Family

ID=27270113

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19973059A NO321140B1 (no) 1995-11-02 1997-07-01 Anvendelse av hydroksylaminderivater som oker den molekylaere chaperonproduksjon, for fremstilling av farmasoytiske preparater, samt nye slike hydroksylaminderivater og farmasoytiske preparater som inneholder de nye hydroksylaminderivater.

Country Status (31)

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US (4) US6653326B1 (fr)
EP (1) EP0801649B1 (fr)
JP (2) JP4531865B2 (fr)
KR (1) KR19980700976A (fr)
CN (1) CN1152871C (fr)
AT (1) ATE221880T1 (fr)
AU (1) AU720195B2 (fr)
BG (1) BG63944B1 (fr)
BR (1) BR9607565B1 (fr)
CA (1) CA2209167C (fr)
CZ (1) CZ295562B6 (fr)
DE (1) DE69622840T2 (fr)
DK (1) DK0801649T3 (fr)
EE (1) EE04239B1 (fr)
ES (1) ES2176502T3 (fr)
HR (1) HRP960508B1 (fr)
HU (1) HU222994B1 (fr)
IL (1) IL121126A (fr)
MX (1) MX9704988A (fr)
NO (1) NO321140B1 (fr)
NZ (1) NZ320523A (fr)
PL (1) PL195634B1 (fr)
PT (1) PT801649E (fr)
RS (1) RS49981B (fr)
RU (1) RU2206320C2 (fr)
SI (1) SI0801649T1 (fr)
SK (1) SK284823B6 (fr)
TR (1) TR199700574T1 (fr)
UA (1) UA61050C2 (fr)
WO (1) WO1997016439A1 (fr)
ZA (1) ZA969249B (fr)

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HUT78139A (hu) * 1995-12-22 2000-11-28 BIOREX Kutató és Fejlesztő Rt. Készítmény, különösen a bőr öregedési folyamatainak mérséklésére
UA64716C2 (en) * 1996-08-09 2004-03-15 Pharmaceuticals for therapy or prevention of illnesses connected with dysfunction of vascular endothelial cells
AU5296799A (en) * 1998-08-03 2000-02-28 N-Gene Kutato Kft. Pharmaceutical compositions against autoimmune diseases
HU226617B1 (en) * 1998-12-14 2009-04-28 Cytrx Corp Optically active pyridyl-4h-1,2,4-oxadiazine derivatives, and pharmaceutical composition containing the compound as active ingredient
HUP9900475D0 (en) * 1999-02-26 1999-04-28 Biorex Kutato Fejlesztoe Kft O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component
FR2792832B1 (fr) * 1999-04-28 2002-05-10 Codif Internat Sa Procede de protection de la peau pour la prevenir de son vieillissement cellulaire
HUP0001583A2 (hu) * 2000-04-18 2002-11-28 BIOREX Kutató és Fejlesztő Rt. Egy piridin-1-oxid-származék és eljárás annak átalakítására gyógyászati hatású vegyületekké
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