NO309238B1 - Fremstilling av proteiner ved bruk av homolog rekombinasjon - Google Patents
Fremstilling av proteiner ved bruk av homolog rekombinasjon Download PDFInfo
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- NO309238B1 NO309238B1 NO912642A NO912642A NO309238B1 NO 309238 B1 NO309238 B1 NO 309238B1 NO 912642 A NO912642 A NO 912642A NO 912642 A NO912642 A NO 912642A NO 309238 B1 NO309238 B1 NO 309238B1
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- gene
- cells
- amplifiable
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- host cells
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Classifications
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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- C12N2800/00—Nucleic acids vectors
- C12N2800/20—Pseudochromosomes, minichrosomosomes
- C12N2800/206—Pseudochromosomes, minichrosomosomes of yeast origin, e.g. YAC, 2u
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- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
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- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US43206989A | 1989-11-06 | 1989-11-06 | |
PCT/US1990/006436 WO1991006667A1 (en) | 1989-11-06 | 1990-11-06 | Production of proteins using homologous recombination |
Publications (3)
Publication Number | Publication Date |
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NO912642D0 NO912642D0 (no) | 1991-07-05 |
NO912642L NO912642L (no) | 1991-09-05 |
NO309238B1 true NO309238B1 (no) | 2001-01-02 |
Family
ID=23714629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO912642A NO309238B1 (no) | 1989-11-06 | 1991-07-05 | Fremstilling av proteiner ved bruk av homolog rekombinasjon |
Country Status (14)
Country | Link |
---|---|
US (3) | US5578461A (ja) |
EP (3) | EP0452484B2 (ja) |
JP (2) | JPH04505104A (ja) |
KR (1) | KR100233781B1 (ja) |
AT (2) | ATE139574T1 (ja) |
AU (1) | AU635844B2 (ja) |
CA (1) | CA2045175C (ja) |
DE (2) | DE69027526T3 (ja) |
DK (2) | DK0747485T3 (ja) |
ES (2) | ES2090297T5 (ja) |
GR (2) | GR3021105T3 (ja) |
NO (1) | NO309238B1 (ja) |
SG (2) | SG122763A1 (ja) |
WO (2) | WO1991006666A1 (ja) |
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ES2090297T5 (es) * | 1989-11-06 | 2005-03-01 | Cell Genesys, Inc. | Produccion de proteinas que utilizan recombinacion homologa. |
US5272071A (en) * | 1989-12-22 | 1993-12-21 | Applied Research Systems Ars Holding N.V. | Method for the modification of the expression characteristics of an endogenous gene of a given cell line |
EP0779362B2 (en) * | 1989-12-22 | 2012-06-13 | Laboratoires Serono SA | DNA constructs for endogenous gene activation and expression modification |
PT101031B (pt) * | 1991-11-05 | 2002-07-31 | Transkaryotic Therapies Inc | Processo para o fornecimento de proteinas por terapia genetica |
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1990
- 1990-11-06 ES ES91900640T patent/ES2090297T5/es not_active Expired - Lifetime
- 1990-11-06 JP JP3500807A patent/JPH04505104A/ja active Pending
- 1990-11-06 DE DE69027526T patent/DE69027526T3/de not_active Expired - Fee Related
- 1990-11-06 AU AU77407/91A patent/AU635844B2/en not_active Ceased
- 1990-11-06 AT AT91900640T patent/ATE139574T1/de not_active IP Right Cessation
- 1990-11-06 WO PCT/US1990/006425 patent/WO1991006666A1/en unknown
- 1990-11-06 SG SG200205236A patent/SG122763A1/en unknown
- 1990-11-06 EP EP91900640A patent/EP0452484B2/en not_active Expired - Lifetime
- 1990-11-06 WO PCT/US1990/006436 patent/WO1991006667A1/en active IP Right Grant
- 1990-11-06 ES ES95119039T patent/ES2127458T3/es not_active Expired - Lifetime
- 1990-11-06 EP EP95119039A patent/EP0747485B1/en not_active Revoked
- 1990-11-06 DE DE69032809T patent/DE69032809T2/de not_active Revoked
- 1990-11-06 AT AT95119039T patent/ATE174058T1/de not_active IP Right Cessation
- 1990-11-06 CA CA002045175A patent/CA2045175C/en not_active Expired - Lifetime
- 1990-11-06 EP EP98115060A patent/EP0945515A3/en not_active Withdrawn
- 1990-11-06 KR KR1019910700717A patent/KR100233781B1/ko not_active IP Right Cessation
- 1990-11-06 DK DK95119039T patent/DK0747485T3/da active
- 1990-11-06 DK DK91900640.3T patent/DK0452484T3/da active
- 1990-11-06 SG SG9604355A patent/SG88714A1/en unknown
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1991
- 1991-07-05 NO NO912642A patent/NO309238B1/no unknown
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1993
- 1993-08-05 US US08/102,567 patent/US5578461A/en not_active Expired - Lifetime
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1995
- 1995-06-05 US US08/462,947 patent/US6015708A/en not_active Expired - Fee Related
- 1995-06-06 US US08/467,244 patent/US5981214A/en not_active Expired - Lifetime
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1996
- 1996-09-19 GR GR960402466T patent/GR3021105T3/el unknown
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1999
- 1999-02-10 GR GR990400414T patent/GR3029328T3/el unknown
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2000
- 2000-12-06 JP JP2000371763A patent/JP2001186897A/ja not_active Withdrawn
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