|
CN101304748A
(zh)
|
2005-08-22 |
2008-11-12 |
加利福尼亚大学董事会 |
Tlr激动剂
|
|
EP2029597A4
(en)
*
|
2006-05-31 |
2011-11-23 |
Univ California |
purine analogs
|
|
PL2510946T3
(pl)
|
2007-02-07 |
2015-12-31 |
Univ California |
Koniugaty syntetycznych agonistów tlr i ich zastosowania
|
|
EP2259788A4
(en)
*
|
2008-02-07 |
2011-03-16 |
Univ California |
TREATMENT OF BLADDER DISEASES WITH A TLR7 ACTIVATOR
|
|
TW201639852A
(zh)
|
2008-12-09 |
2016-11-16 |
吉李德科學股份有限公司 |
用於製備可用作類鐸受體調節劑之化合物的中間體化合物
|
|
KR20110117705A
(ko)
*
|
2009-02-11 |
2011-10-27 |
더 리전트 오브 더 유니버시티 오브 캘리포니아 |
톨-유사 수용체 조정제 및 질병의 치료
|
|
CN104945420A
(zh)
|
2009-06-29 |
2015-09-30 |
因塞特公司 |
作为pi3k抑制剂的嘧啶酮类
|
|
NO2491035T3
(cg-RX-API-DMAC10.html)
|
2009-10-22 |
2018-01-27 |
|
|
|
US8759359B2
(en)
*
|
2009-12-18 |
2014-06-24 |
Incyte Corporation |
Substituted heteroaryl fused derivatives as PI3K inhibitors
|
|
AR079529A1
(es)
*
|
2009-12-18 |
2012-02-01 |
Incyte Corp |
Derivados arilo y heteroarilo sustituidos y fundidos como inhibidores de la pi3k
|
|
WO2011130342A1
(en)
|
2010-04-14 |
2011-10-20 |
Incyte Corporation |
FUSED DERIVATIVES AS ΡI3Κδ INHIBITORS
|
|
US9062055B2
(en)
|
2010-06-21 |
2015-06-23 |
Incyte Corporation |
Fused pyrrole derivatives as PI3K inhibitors
|
|
CA2822070C
(en)
|
2010-12-20 |
2019-09-17 |
Incyte Corporation |
N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
|
|
US8754114B2
(en)
|
2010-12-22 |
2014-06-17 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
|
|
US9108984B2
(en)
|
2011-03-14 |
2015-08-18 |
Incyte Corporation |
Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors
|
|
US9126948B2
(en)
|
2011-03-25 |
2015-09-08 |
Incyte Holdings Corporation |
Pyrimidine-4,6-diamine derivatives as PI3K inhibitors
|
|
JP6046694B2
(ja)
|
2011-04-08 |
2016-12-21 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染治療用のピリミジン誘導体
|
|
JP6138764B2
(ja)
|
2011-05-16 |
2017-05-31 |
ロマーク ラボラトリーズ エル.シー. |
ウイルス性疾患、ガンおよび細胞内感染により引き起こされる疾患の予防および処置のためのチアゾリド化合物の使用
|
|
AU2016201747B2
(en)
*
|
2011-05-16 |
2017-06-01 |
Romark Laboratories, L.C. |
Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infections
|
|
AR087760A1
(es)
|
2011-09-02 |
2014-04-16 |
Incyte Corp |
Heterociclilaminas como inhibidores de pi3k
|
|
ES2690082T3
(es)
*
|
2011-11-09 |
2018-11-19 |
Janssen Sciences Ireland Uc |
Derivados de purina para el tratamiento de infecciones virales
|
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
|
CN107652289B
(zh)
|
2012-06-13 |
2020-07-21 |
因塞特控股公司 |
作为fgfr抑制剂的取代的三环化合物
|
|
SI2872515T1
(sl)
|
2012-07-13 |
2016-10-28 |
Janssen Sciences Ireland Uc |
Makrociklični purini za zdravljanje virusnih infekcij
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
TR201807076T4
(tr)
|
2012-10-10 |
2018-06-21 |
Janssen Sciences Ireland Uc |
Viral enfeksiyonların ve diğer hastalıkların tedavisine yönelik pirolo[3,2-d]pirimidin derivatları.
|
|
CA2886635C
(en)
|
2012-11-16 |
2021-01-05 |
Janssen Sciences Ireland Uc |
Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
EP2958900B1
(en)
|
2013-02-21 |
2019-04-10 |
Janssen Sciences Ireland Unlimited Company |
2-aminopyrimidine derivatives for the treatment of viral infections
|
|
MX366481B
(es)
|
2013-03-29 |
2019-07-09 |
Janssen Sciences Ireland Uc |
Deaza-purinonas macrociclicas para el tratamiento de infecciones virales.
|
|
JP6449244B2
(ja)
|
2013-04-19 |
2019-01-09 |
インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation |
Fgfr抑制剤としての二環式複素環
|
|
EA034674B1
(ru)
|
2013-05-24 |
2020-03-05 |
Янссен Сайенсиз Айрлэнд Юси |
Производные пиридона для лечения нарушений, в которое вовлечены модуляции tlr7 и/или tlr8
|
|
CN109369643B
(zh)
|
2013-06-27 |
2021-05-18 |
爱尔兰詹森科学公司 |
用于治疗病毒感染和其他疾病的吡咯并[3,2-d]嘧啶衍生物
|
|
CN105492446B
(zh)
|
2013-07-30 |
2018-08-03 |
爱尔兰詹森科学公司 |
用于治疗病毒性感染的噻吩并[3,2-d]嘧啶衍生物
|
|
US10077277B2
(en)
|
2014-06-11 |
2018-09-18 |
Incyte Corporation |
Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors
|
|
NZ728072A
(en)
*
|
2014-07-11 |
2018-06-29 |
Gilead Sciences Inc |
Modulators of toll-like receptors for the treatment of hiv
|
|
CA2960436C
(en)
|
2014-09-16 |
2021-01-05 |
Gilead Sciences, Inc. |
Solid forms of a toll-like receptor modulator
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
EP3939985B1
(en)
|
2014-12-26 |
2024-05-08 |
Emory University |
Pharmaceutical compositions comprising n4-hydroxycytidine derivatives for the treatment or prevention of influenza or coronavirus infections
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
ES2751669T3
(es)
|
2015-02-20 |
2020-04-01 |
Incyte Corp |
Heterociclos bicíclicos como inhibidores FGFR
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
PT3831833T
(pt)
|
2015-02-27 |
2023-02-06 |
Incyte Corp |
Processos para a preparação de um inibidor pi3k
|
|
MY188211A
(en)
|
2015-03-04 |
2021-11-24 |
Gilead Sciences Inc |
Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds
|
|
WO2016183060A1
(en)
|
2015-05-11 |
2016-11-17 |
Incyte Corporation |
Process for the synthesis of a phosphoinositide 3-kinase inhibitor
|
|
US9988401B2
(en)
|
2015-05-11 |
2018-06-05 |
Incyte Corporation |
Crystalline forms of a PI3K inhibitor
|
|
JP2018525412A
(ja)
|
2015-08-26 |
2018-09-06 |
ギリアード サイエンシーズ, インコーポレイテッド |
重水素化トール様受容体調節因子
|
|
EA202091898A1
(ru)
|
2015-12-15 |
2021-06-22 |
Джилид Сайэнс, Инк. |
Антитела, нейтрализующие вирус иммунодефицита человека
|
|
BR112017002594A2
(pt)
|
2015-12-17 |
2017-12-19 |
Gilead Sciences Inc |
compostos inibidores de cinase de ligação de tank
|
|
CN109641874A
(zh)
|
2016-05-10 |
2019-04-16 |
C4医药公司 |
用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体
|
|
CN109790143A
(zh)
|
2016-05-10 |
2019-05-21 |
C4医药公司 |
用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体
|
|
CN109562107A
(zh)
|
2016-05-10 |
2019-04-02 |
C4医药公司 |
用于靶蛋白降解的杂环降解决定子体
|
|
ES2990061T3
(es)
|
2016-05-10 |
2024-11-28 |
C4 Therapeutics Inc |
Degronímeros espirocíclicos para la degradación de proteínas diana
|
|
US11697851B2
(en)
|
2016-05-24 |
2023-07-11 |
The Regents Of The University Of California |
Early ovarian cancer detection diagnostic test based on mRNA isoforms
|
|
BR102017010009A2
(pt)
|
2016-05-27 |
2017-12-12 |
Gilead Sciences, Inc. |
Compounds for the treatment of hepatitis b virus infection
|
|
CN109414508A
(zh)
|
2016-05-27 |
2019-03-01 |
吉利德科学公司 |
使用ns5a、ns5b或ns3抑制剂治疗乙型肝炎病毒感染的方法
|
|
CA3027471A1
(en)
|
2016-07-01 |
2018-01-04 |
Janssen Sciences Ireland Unlimited Company |
Dihydropyranopyrimidines for the treatment of viral infections
|
|
JOP20190024A1
(ar)
|
2016-08-26 |
2019-02-19 |
Gilead Sciences Inc |
مركبات بيروليزين بها استبدال واستخداماتها
|
|
MA46038B1
(fr)
*
|
2016-08-29 |
2021-05-31 |
Hoffmann La Roche |
Composés de sulfonimidoylpurinone substitués dans la position 7 pour le traitement et la prophylaxie d'infection virale
|
|
WO2018045150A1
(en)
|
2016-09-02 |
2018-03-08 |
Gilead Sciences, Inc. |
4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
|
|
MA46093A
(fr)
|
2016-09-02 |
2021-05-19 |
Gilead Sciences Inc |
Composés modulateurs du recepteur de type toll
|
|
CA3031585A1
(en)
*
|
2016-09-09 |
2018-03-15 |
Novartis Ag |
Compounds and compositions as inhibitors of endosomal toll-like receptors
|
|
EA038646B1
(ru)
|
2016-09-29 |
2021-09-28 |
Янссен Сайенсиз Айрлэнд Анлимитед Компани |
Пиримидиновые пролекарства для лечения вирусных инфекций и других заболеваний
|
|
FI3526323T3
(fi)
|
2016-10-14 |
2023-06-06 |
Prec Biosciences Inc |
Hepatiitti B -viruksen genomissa oleville tunnistussekvensseille spesifisiä muokattuja meganukleaaseja
|
|
PT3546457T
(pt)
*
|
2016-11-28 |
2021-08-06 |
Jiangsu Hengrui Medicine Co |
Derivado de pirazolo-heteroarílico, método de preparação e a utilização médica do mesmo
|
|
AR110768A1
(es)
|
2017-01-31 |
2019-05-02 |
Gilead Sciences Inc |
Formas cristalinas de tenofovir alafenamida
|
|
JOP20180008A1
(ar)
|
2017-02-02 |
2019-01-30 |
Gilead Sciences Inc |
مركبات لعلاج إصابة بعدوى فيروس الالتهاب الكبدي b
|
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
CN110769822A
(zh)
|
2017-06-20 |
2020-02-07 |
C4医药公司 |
用于蛋白降解的n/o-连接的降解决定子和降解决定子体
|
|
US10508115B2
(en)
|
2017-08-16 |
2019-12-17 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor
|
|
US10457681B2
(en)
*
|
2017-08-16 |
2019-10-29 |
Bristol_Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor
|
|
US10472361B2
(en)
|
2017-08-16 |
2019-11-12 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor
|
|
US10494370B2
(en)
|
2017-08-16 |
2019-12-03 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor
|
|
US10487084B2
(en)
*
|
2017-08-16 |
2019-11-26 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor
|
|
JP6934562B2
(ja)
|
2017-08-22 |
2021-09-15 |
ギリアード サイエンシーズ, インコーポレイテッド |
治療用複素環式化合物
|
|
WO2019084060A1
(en)
|
2017-10-24 |
2019-05-02 |
Silverback Therapeutics, Inc. |
CONJUGATES AND METHODS OF USE FOR THE SELECTIVE DELIVERY OF IMMUNOMODULATORY AGENTS
|
|
JP2021035910A
(ja)
*
|
2017-11-01 |
2021-03-04 |
大日本住友製薬株式会社 |
置換プリン化合物
|
|
WO2019099564A1
(en)
|
2017-11-14 |
2019-05-23 |
Children's Medical Center Corporation |
Novel imidazopyrimidine compounds and uses thereof
|
|
JP7382316B2
(ja)
*
|
2017-11-14 |
2023-11-16 |
ザ チルドレンズ メディカル センター コーポレーション |
ヒト免疫応答をモジュレートするためのイミダゾピリミジンの使用
|
|
ES2995458T3
(en)
|
2017-12-07 |
2025-02-10 |
Univ Emory |
N4-hydroxycytidine derivative and anti-viral uses related thereto
|
|
AU2018385693A1
(en)
|
2017-12-15 |
2020-06-18 |
Silverback Therapeutics, Inc. |
Antibody construct-drug conjugate for the treatment of hepatitis
|
|
AU2018392212B9
(en)
|
2017-12-20 |
2021-03-18 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
|
|
WO2019123340A1
(en)
|
2017-12-20 |
2019-06-27 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
WO2019155042A1
(en)
|
2018-02-12 |
2019-08-15 |
F. Hoffmann-La Roche Ag |
Novel sulfone compounds and derivatives for the treatment and prophylaxis of virus infection
|
|
KR102708681B1
(ko)
|
2018-02-13 |
2024-09-26 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
|
CA3091142C
(en)
|
2018-02-26 |
2023-04-11 |
Gilead Sciences, Inc. |
Substituted pyrrolizine compounds and uses thereof
|
|
PE20211456A1
(es)
*
|
2018-02-28 |
2021-08-05 |
Hoffmann La Roche |
Compuestos de sulfonimidoilpurinona 7-sustituidos y sus derivados para el tratamiento y prevencion del cancer de higado
|
|
TW202415645A
(zh)
|
2018-03-01 |
2024-04-16 |
愛爾蘭商健生科學愛爾蘭無限公司 |
2,4-二胺基喹唑啉衍生物及其醫學用途
|
|
CN110317202B
(zh)
*
|
2018-03-30 |
2021-12-24 |
江苏恒瑞医药股份有限公司 |
氰基吡咯并杂芳基类衍生物、其制备方法及其在医药上的应用
|
|
WO2019195181A1
(en)
|
2018-04-05 |
2019-10-10 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis b virus protein x
|
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
2,2,─環二核苷酸
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
CN108295060A
(zh)
*
|
2018-04-08 |
2018-07-20 |
王长国 |
一种tlr7激动剂在增强cik细胞对肿瘤细胞杀伤力方面的应用
|
|
US11142750B2
(en)
|
2018-04-12 |
2021-10-12 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome
|
|
WO2019196918A1
(zh)
*
|
2018-04-13 |
2019-10-17 |
罗欣药业(上海)有限公司 |
五元杂环并嘧啶类化合物、药物组合物及用途
|
|
EP3781556B1
(en)
|
2018-04-19 |
2025-06-18 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
|
US11485741B2
(en)
|
2018-04-24 |
2022-11-01 |
Bristol-Myers Squibb Company |
Macrocyclic toll-like receptor 7 (TLR7) agonists
|
|
WO2019211799A1
(en)
|
2018-05-03 |
2019-11-07 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide
|
|
PE20210919A1
(es)
|
2018-05-04 |
2021-05-19 |
Incyte Corp |
Sales de un inhibidor de fgfr
|
|
CN119241541A
(zh)
|
2018-05-04 |
2025-01-03 |
因赛特公司 |
Fgfr抑制剂的固体形式和其制备方法
|
|
CN110526917B
(zh)
*
|
2018-05-25 |
2021-09-03 |
江苏恒瑞医药股份有限公司 |
一种吡唑并杂芳基类衍生物的可药用盐、晶型及其制备方法
|
|
CN110526918B
(zh)
*
|
2018-05-25 |
2021-09-03 |
江苏恒瑞医药股份有限公司 |
一种吡唑并杂芳基类衍生物的晶型及制备方法
|
|
MX2020012651A
(es)
*
|
2018-05-25 |
2021-02-02 |
Jiangsu Hengrui Medicine Co |
Forma de cristal de clorhidrato de derivado de pirazoloheteroarilo, y metodo de preparacion.
|
|
KR102884803B1
(ko)
|
2018-06-01 |
2025-11-12 |
인사이트 코포레이션 |
Pi3k 관련 장애의 치료를 위한 투여 요법
|
|
CA3102859A1
(en)
|
2018-07-03 |
2020-01-09 |
Gilead Sciences, Inc. |
Antibodies that target hiv gp120 and methods of use
|
|
WO2020010200A1
(en)
|
2018-07-06 |
2020-01-09 |
Gilead Sciences, Inc. |
Therapeutic heterocyclic compounds
|
|
US11186579B2
(en)
|
2018-07-06 |
2021-11-30 |
Gilead Sciences, Inc. |
Therapeutic heterocyclic compounds
|
|
PL3820572T3
(pl)
|
2018-07-13 |
2024-02-26 |
Gilead Sciences, Inc. |
Inhibitory pd-1/pd-l1
|
|
WO2020028097A1
(en)
|
2018-08-01 |
2020-02-06 |
Gilead Sciences, Inc. |
Solid forms of (r)-11-(methoxymethyl)-12-(3-methoxypropoxy)-3,3-dimethyl-8-0x0-2,3,8,13b-tetrahydro-1h-pyrido[2,1-a]pyrrolo[1,2-c] phthalazine-7-c arboxylic acid
|
|
US11554120B2
(en)
|
2018-08-03 |
2023-01-17 |
Bristol-Myers Squibb Company |
1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor
|
|
JP2022500414A
(ja)
|
2018-09-12 |
2022-01-04 |
シルバーバック セラピューティックス インコーポレイテッド |
免疫刺激性コンジュゲートにより疾患を処置する方法および組成物
|
|
CN111072667A
(zh)
*
|
2018-10-22 |
2020-04-28 |
罗欣药业(上海)有限公司 |
五元或六元杂环并嘧啶类化合物及其用途
|
|
CA3117199C
(en)
|
2018-10-24 |
2024-03-19 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
|
CR20210215A
(es)
|
2018-10-31 |
2021-06-17 |
Gilead Sciences Inc |
Compuestos de 6-azabencimidazol sustituidos como inhibidores de hpk1
|
|
CN117105933A
(zh)
|
2018-10-31 |
2023-11-24 |
吉利德科学公司 |
具有hpk1抑制活性的取代的6-氮杂苯并咪唑化合物
|
|
WO2020178768A1
(en)
|
2019-03-07 |
2020-09-10 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
|
KR102808642B1
(ko)
|
2019-03-07 |
2025-05-14 |
인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리 에이에스 씨알 브이.브이.아이. |
3'3'-사이클릭 다이뉴클레오티드 및 이의 프로드럭
|
|
CA3129022C
(en)
|
2019-03-07 |
2023-08-01 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotides and prodrugs thereof
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
CN119462659A
(zh)
|
2019-03-22 |
2025-02-18 |
吉利德科学公司 |
桥连三环氨基甲酰基吡啶酮化合物及其药学用途
|
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI751516B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI762925B
(zh)
|
2019-05-21 |
2022-05-01 |
美商基利科學股份有限公司 |
鑑別對使用gp120 v3聚醣導向之抗體的治療敏感之hiv病患的方法
|
|
US11453681B2
(en)
|
2019-05-23 |
2022-09-27 |
Gilead Sciences, Inc. |
Substituted eneoxindoles and uses thereof
|
|
US20220305115A1
(en)
|
2019-06-18 |
2022-09-29 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and pyridopyrimidine derivatives
|
|
WO2020257407A1
(en)
|
2019-06-19 |
2020-12-24 |
Silverback Therapeutics, Inc. |
Anti-mesothelin antibodies and immunoconjugates thereof
|
|
CR20210687A
(es)
|
2019-06-25 |
2022-03-03 |
Gilead Sciences Inc |
PROTEÍNAS DE FUSIÓN FLT3L-Fc Y MÉTODOS DE USO
|
|
TWI879779B
(zh)
|
2019-06-28 |
2025-04-11 |
美商基利科學股份有限公司 |
類鐸受體調節劑化合物的製備方法
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
CN120775062A
(zh)
|
2019-07-16 |
2025-10-14 |
吉利德科学公司 |
Hiv疫苗及其制备和使用方法
|
|
WO2021011891A1
(en)
|
2019-07-18 |
2021-01-21 |
Gilead Sciences, Inc. |
Long-acting formulations of tenofovir alafenamide
|
|
WO2021026803A1
(en)
*
|
2019-08-14 |
2021-02-18 |
Novartis Ag |
Piperidinyl-methyl-purineamines as nsd2 inhibitors and anti-cancer agents
|
|
EP4017476A1
(en)
|
2019-08-19 |
2022-06-29 |
Gilead Sciences, Inc. |
Pharmaceutical formulations of tenofovir alafenamide
|
|
AU2020349613B2
(en)
|
2019-09-19 |
2025-11-13 |
Danmarks Tekniske Universitet |
Immune stimulating micelle composition
|
|
SI4037708T1
(sl)
|
2019-09-30 |
2025-01-31 |
Gilead Sciences, Inc. |
Cepiva proti hbv in postopki zdravljenja hbv
|
|
WO2021067644A1
(en)
|
2019-10-01 |
2021-04-08 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
GEP20247679B
(en)
|
2019-10-14 |
2024-10-10 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
ES2973832T3
(es)
|
2019-10-18 |
2024-06-24 |
Forty Seven Inc |
Terapias combinadas para el tratamiento de síndromes mielodisplásicos y leucemia mieloide aguda
|
|
MY209360A
(en)
|
2019-10-31 |
2025-07-03 |
Forty Seven Llc |
Anti-cd47 and anti-cd20 based treatment of blood cancer
|
|
TWI778443B
(zh)
|
2019-11-12 |
2022-09-21 |
美商基利科學股份有限公司 |
Mcl1抑制劑
|
|
CA3163875A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
IL293001A
(en)
|
2019-12-04 |
2022-07-01 |
Incyte Corp |
Derivatives of fgfr repressors
|
|
DK4069729T3
(da)
|
2019-12-06 |
2025-04-07 |
Prec Biosciences Inc |
Optimerede, modificerede meganukleaser med specificitet for en genkendelsessekvens i hepatitis b-virusgenomet
|
|
PL4081305T3
(pl)
|
2019-12-24 |
2025-02-10 |
Carna Biosciences, Inc. |
Związki modulujące kinazę diacyloglicerolową
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021154663A1
(en)
|
2020-01-27 |
2021-08-05 |
Bristol-Myers Squibb Company |
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
|
|
WO2021154666A1
(en)
|
2020-01-27 |
2021-08-05 |
Bristol-Myers Squibb Company |
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
|
|
JP7712941B2
(ja)
|
2020-01-27 |
2025-07-24 |
ブリストル-マイヤーズ スクイブ カンパニー |
トール様受容体7(TLR7)アゴニストとしての1H-ピラゾロ[4,3-d]ピリミジン化合物
|
|
JP7712942B2
(ja)
|
2020-01-27 |
2025-07-24 |
ブリストル-マイヤーズ スクイブ カンパニー |
トール様受容体7(TLR7)アゴニストとしての1H-ピラゾロ[4,3-d]ピリミジン化合物
|
|
EP4097107A1
(en)
|
2020-01-27 |
2022-12-07 |
Bristol-Myers Squibb Company |
C3-substituted 1h-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (tlr7) agonists
|
|
KR20220132590A
(ko)
|
2020-01-27 |
2022-09-30 |
브리스톨-마이어스 스큅 컴퍼니 |
톨-유사 수용체 7 (TLR7) 효능제로서의 1H-피라졸로[4,3-d]피리미딘 화합물
|
|
EP4097108A1
(en)
|
2020-01-27 |
2022-12-07 |
Bristol-Myers Squibb Company |
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
|
|
WO2021154668A1
(en)
|
2020-01-27 |
2021-08-05 |
Bristol-Myers Squibb Company |
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
|
|
US20230131192A1
(en)
|
2020-01-27 |
2023-04-27 |
Bristol-Myers Squibb Company |
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
|
|
EP4103285A2
(en)
|
2020-02-14 |
2022-12-21 |
Jounce Therapeutics, Inc. |
Antibodies and fusion proteins that bind to ccr8 and uses thereof
|
|
JP7735291B2
(ja)
|
2020-02-21 |
2025-09-08 |
エーアールエス ファーマシューティカルズ、インコーポレイテッド |
ネクチン-4抗体コンジュゲートおよびその使用
|
|
EP4121437A1
(en)
|
2020-03-20 |
2023-01-25 |
Gilead Sciences, Inc. |
Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same
|
|
CA3181922A1
(en)
|
2020-05-01 |
2021-11-04 |
Gilead Sciences, Inc. |
Cd73 inhibiting 2,4-dioxopyrimidine compounds
|
|
WO2021236944A1
(en)
|
2020-05-21 |
2021-11-25 |
Gilead Sciences, Inc. |
Pharmaceutical compositions comprising bictegravir
|
|
CA3183993A1
(en)
|
2020-07-01 |
2022-01-06 |
Peter R. Baum |
Anti-asgr1 antibody conjugates and uses thereof
|
|
JP7712352B2
(ja)
|
2020-08-07 |
2025-07-23 |
ギリアード サイエンシーズ, インコーポレイテッド |
ホスホンアミドヌクレオチド類似体のプロドラッグ及びその薬学的使用
|
|
US20240124486A1
(en)
*
|
2020-09-27 |
2024-04-18 |
Shanghai Visonpharma Co., Ltd. |
Macrocyclic tlr7 agonist, preparation method therefor, pharmaceutical composition and use thereof
|
|
TW202406932A
(zh)
|
2020-10-22 |
2024-02-16 |
美商基利科學股份有限公司 |
介白素2-Fc融合蛋白及使用方法
|
|
KR20230107288A
(ko)
|
2020-11-11 |
2023-07-14 |
길리애드 사이언시즈, 인코포레이티드 |
gp120 CD4 결합 부위-지향 항체를 이용한 요법에 감수성인 HIV 환자를 식별하는 방법
|
|
KR102514860B1
(ko)
*
|
2020-12-01 |
2023-03-29 |
한국과학기술연구원 |
5-ht7 세로토닌 수용체 활성 저해용 바이페닐 피롤리딘 및 바이페닐 다이하이드로이미다졸 유도체 및 이를 유효성분으로 포함하는 약학 조성물
|
|
AU2022253902A1
(en)
|
2021-04-10 |
2023-11-02 |
Genmab A/S |
Folr1 binding agents, conjugates thereof and methods of using the same
|
|
JP2024513575A
(ja)
|
2021-04-12 |
2024-03-26 |
インサイト・コーポレイション |
Fgfr阻害剤及びネクチン-4標的化剤を含む併用療法
|
|
TW202302145A
(zh)
|
2021-04-14 |
2023-01-16 |
美商基利科學股份有限公司 |
CD47/SIRPα結合及NEDD8活化酶E1調節次單元之共抑制以用於治療癌症
|
|
WO2022226317A1
(en)
|
2021-04-23 |
2022-10-27 |
Profoundbio Us Co. |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
|
US20240269142A1
(en)
|
2021-05-13 |
2024-08-15 |
Gilead Sciences, Inc. |
COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS
|
|
US20220389394A1
(en)
|
2021-05-18 |
2022-12-08 |
Gilead Sciences, Inc. |
METHODS OF USING FLT3L-Fc FUSION PROTEINS
|
|
WO2022261160A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
AR126101A1
(es)
|
2021-06-09 |
2023-09-13 |
Incyte Corp |
Heterociclos tricíclicos como inhibidores de fgfr
|
|
EP4359411A1
(en)
|
2021-06-23 |
2024-05-01 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
JP7686086B2
(ja)
|
2021-06-23 |
2025-05-30 |
ギリアード サイエンシーズ, インコーポレイテッド |
ジアシルグリエルコール(diacylglyercol)キナーゼ調節化合物
|
|
WO2022271684A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
CN117396478A
(zh)
|
2021-06-23 |
2024-01-12 |
吉利德科学公司 |
二酰基甘油激酶调节化合物
|
|
TW202320857A
(zh)
|
2021-07-06 |
2023-06-01 |
美商普方生物製藥美國公司 |
連接子、藥物連接子及其結合物及其使用方法
|
|
TWI857377B
(zh)
|
2021-10-28 |
2024-10-01 |
美商基利科學股份有限公司 |
嗒-3(2h)-酮衍生物
|
|
MX2024005066A
(es)
|
2021-10-29 |
2024-05-24 |
Gilead Sciences Inc |
Compuestos de cd73.
|
|
FI4445900T3
(fi)
|
2021-12-03 |
2025-08-05 |
Gilead Sciences Inc |
Terapeuttisia yhdisteitä hiv-virusinfektiota varten
|
|
TW202342448A
(zh)
|
2021-12-03 |
2023-11-01 |
美商基利科學股份有限公司 |
用於hiv病毒感染之治療性化合物
|
|
JP7736929B2
(ja)
|
2021-12-03 |
2025-09-09 |
ギリアード サイエンシーズ, インコーポレイテッド |
Hivウイルス感染症のための治療化合物
|
|
US20230203202A1
(en)
|
2021-12-08 |
2023-06-29 |
Dragonfly Therapeutics, Inc. |
Proteins binding nkg2d, cd16 and 5t4
|
|
WO2023107954A1
(en)
|
2021-12-08 |
2023-06-15 |
Dragonfly Therapeutics, Inc. |
Antibodies targeting 5t4 and uses thereof
|
|
US12122764B2
(en)
|
2021-12-22 |
2024-10-22 |
Gilead Sciences, Inc. |
IKAROS zinc finger family degraders and uses thereof
|
|
WO2023122581A2
(en)
|
2021-12-22 |
2023-06-29 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
|
TW202340168A
(zh)
|
2022-01-28 |
2023-10-16 |
美商基利科學股份有限公司 |
Parp7抑制劑
|
|
EP4487845A4
(en)
*
|
2022-03-03 |
2025-02-19 |
Seoul National University Hospital |
Composition for preventing, alleviating or treating dry eye syndrome or meibomian gland dysfunction
|
|
PE20242225A1
(es)
|
2022-03-17 |
2024-11-19 |
Gilead Sciences Inc |
Degradadores de dedos de zinc de la familia ikaros y usos de estos
|
|
JP2025509662A
(ja)
|
2022-03-24 |
2025-04-11 |
ギリアード サイエンシーズ, インコーポレイテッド |
Trop-2発現がんを治療するための併用療法
|
|
TWI876305B
(zh)
|
2022-04-05 |
2025-03-11 |
美商基利科學股份有限公司 |
用於治療結腸直腸癌之組合療法
|
|
TWI856796B
(zh)
|
2022-04-06 |
2024-09-21 |
美商基利科學股份有限公司 |
橋聯三環胺甲醯基吡啶酮化合物及其用途
|
|
AU2023256670A1
(en)
|
2022-04-21 |
2024-10-17 |
Gilead Sciences, Inc. |
Kras g12d modulating compounds
|
|
WO2024006982A1
(en)
|
2022-07-01 |
2024-01-04 |
Gilead Sciences, Inc. |
Therapeutic compounds useful for the prophylactic or therapeutic treatment of an hiv virus infection
|
|
CA3260083A1
(en)
|
2022-07-01 |
2024-01-04 |
Gilead Sciences, Inc. |
CD73 COMPOUNDS
|
|
CN119677546A
(zh)
|
2022-07-12 |
2025-03-21 |
吉利德科学公司 |
Hiv免疫原性多肽和疫苗及其用途
|
|
EP4577242A1
(en)
|
2022-08-26 |
2025-07-02 |
Gilead Sciences, Inc. |
Dosing and scheduling regimen for broadly neutralizing antibodies
|
|
US20240091351A1
(en)
|
2022-09-21 |
2024-03-21 |
Gilead Sciences, Inc. |
FOCAL IONIZING RADIATION AND CD47/SIRPa DISRUPTION ANTICANCER COMBINATION THERAPY
|
|
US20240226130A1
(en)
|
2022-10-04 |
2024-07-11 |
Gilead Sciences, Inc. |
4'-thionucleoside analogues and their pharmaceutical use
|
|
KR20250122479A
(ko)
|
2022-12-22 |
2025-08-13 |
길리애드 사이언시즈, 인코포레이티드 |
Prmt5 억제제 및 이의 용도
|
|
AU2024252725A1
(en)
|
2023-04-11 |
2025-11-06 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
|
AU2024259111A1
(en)
|
2023-04-19 |
2025-10-16 |
Gilead Sciences, Inc. |
Dosing regimen of capsid inhibitor
|
|
KR20250175331A
(ko)
|
2023-04-21 |
2025-12-16 |
길리애드 사이언시즈, 인코포레이티드 |
Prmt5 억제제 및 이의 용도
|
|
US20250011352A1
(en)
|
2023-05-31 |
2025-01-09 |
Gilead Sciences, Inc. |
Solid forms
|
|
US20250042926A1
(en)
|
2023-05-31 |
2025-02-06 |
Gilead Sciences, Inc. |
Therapeutic compounds for hiv
|
|
CN116444522B
(zh)
*
|
2023-06-14 |
2023-08-25 |
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|
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|
|
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|
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|
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|
|
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|
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|
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|
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|
|
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|
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|
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|
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|
|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
|
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|
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|
|
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|
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|
|
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|
|
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|
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|