NO20083175L - Synergistisk analgetisk kombinasjon av opioid analgetikum og cyklooksigenase-2 inhibitor - Google Patents

Synergistisk analgetisk kombinasjon av opioid analgetikum og cyklooksigenase-2 inhibitor

Info

Publication number
NO20083175L
NO20083175L NO20083175A NO20083175A NO20083175L NO 20083175 L NO20083175 L NO 20083175L NO 20083175 A NO20083175 A NO 20083175A NO 20083175 A NO20083175 A NO 20083175A NO 20083175 L NO20083175 L NO 20083175L
Authority
NO
Norway
Prior art keywords
analgesic
inhibitor
cyclooxygenase
combination
synergistic
Prior art date
Application number
NO20083175A
Other languages
English (en)
Other versions
NO335682B1 (no
Inventor
Richard S Sackler
Ronald M Burch
Paul D Goldenheim
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20083175L publication Critical patent/NO20083175L/no
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of NO335682B1 publication Critical patent/NO335682B1/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Det er beskrevet foreliggende oppfinnelse som angår anvendelse av en kombinasjon av et opioid analgetikum sammen med en COX-2 inhibitor.
NO20083175A 1997-09-17 2008-07-16 Farmasøytisk sammensetning omfattende en analgetisk effektiv kombinasjon og anvendelse av nevnte kombinasjon til fremstilling av et farmasøytisk preparat. NO335682B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5919597P 1997-09-17 1997-09-17
PCT/US1998/019516 WO1999013799A1 (en) 1997-09-17 1998-09-17 Synergistic analgesic combination of opioid analgesic and cyclooxygenase-2 inhibitor

Publications (2)

Publication Number Publication Date
NO20083175L true NO20083175L (no) 2000-05-16
NO335682B1 NO335682B1 (no) 2015-01-19

Family

ID=22021415

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20001359A NO325884B1 (no) 1997-09-17 2000-03-15 Enkel farmasoytisk doseringsform med COX-2-inhibitor og oksykodon eller morfin, og anvendelse av COX-2-inhibitor, oksykodon eller morfin, for fremstilling av den samme.
NO20083175A NO335682B1 (no) 1997-09-17 2008-07-16 Farmasøytisk sammensetning omfattende en analgetisk effektiv kombinasjon og anvendelse av nevnte kombinasjon til fremstilling av et farmasøytisk preparat.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20001359A NO325884B1 (no) 1997-09-17 2000-03-15 Enkel farmasoytisk doseringsform med COX-2-inhibitor og oksykodon eller morfin, og anvendelse av COX-2-inhibitor, oksykodon eller morfin, for fremstilling av den samme.

Country Status (27)

Country Link
US (11) US6552031B1 (no)
EP (2) EP1518555B1 (no)
JP (1) JP5077903B2 (no)
KR (1) KR100444195B1 (no)
CN (1) CN1241567C (no)
AT (2) ATE283051T1 (no)
AU (1) AU742097B2 (no)
BR (1) BR9812342A (no)
CA (1) CA2303309C (no)
CY (2) CY1106044T1 (no)
CZ (1) CZ300531B6 (no)
DE (2) DE69827821T2 (no)
DK (1) DK1518555T3 (no)
ES (2) ES2343322T3 (no)
HK (1) HK1030736A1 (no)
HU (2) HU226116B1 (no)
IL (1) IL134987A0 (no)
NO (2) NO325884B1 (no)
NZ (2) NZ503233A (no)
PL (1) PL191966B1 (no)
PT (2) PT1518555E (no)
RS (1) RS49982B (no)
RU (1) RU2232600C2 (no)
SI (1) SI1518555T1 (no)
TR (1) TR200001041T2 (no)
UA (1) UA72193C2 (no)
WO (1) WO1999013799A1 (no)

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