NO20010487D0 - Disubstituert maleimidforbindelse og farmasöytisk anvendelse herav - Google Patents

Disubstituert maleimidforbindelse og farmasöytisk anvendelse herav

Info

Publication number
NO20010487D0
NO20010487D0 NO20010487A NO20010487A NO20010487D0 NO 20010487 D0 NO20010487 D0 NO 20010487D0 NO 20010487 A NO20010487 A NO 20010487A NO 20010487 A NO20010487 A NO 20010487A NO 20010487 D0 NO20010487 D0 NO 20010487D0
Authority
NO
Norway
Prior art keywords
pharmaceutical use
maleimide compound
disubstituted maleimide
disubstituted
compound
Prior art date
Application number
NO20010487A
Other languages
English (en)
Other versions
NO20010487L (no
Inventor
Takashi Inaba
Masahiro Tanaka
Kenji Sakoda
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of NO20010487D0 publication Critical patent/NO20010487D0/no
Publication of NO20010487L publication Critical patent/NO20010487L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20010487A 1998-07-30 2001-01-29 Disubstituert maleimidforbindelse og farmasøytisk anvendelse herav NO20010487L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21507098 1998-07-30
PCT/JP1999/004085 WO2000006564A1 (fr) 1998-07-30 1999-07-28 Composes de maleimide disubstitues et utilisation en medecine de ces derniers

Publications (2)

Publication Number Publication Date
NO20010487D0 true NO20010487D0 (no) 2001-01-29
NO20010487L NO20010487L (no) 2001-03-28

Family

ID=16666269

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20010487A NO20010487L (no) 1998-07-30 2001-01-29 Disubstituert maleimidforbindelse og farmasøytisk anvendelse herav

Country Status (12)

Country Link
EP (1) EP1120414A1 (no)
KR (1) KR20010085305A (no)
CN (1) CN1320123A (no)
AU (1) AU4929999A (no)
BR (1) BR9912612A (no)
CA (1) CA2338866A1 (no)
HU (1) HUP0103381A3 (no)
ID (1) ID27510A (no)
IL (1) IL141080A0 (no)
NO (1) NO20010487L (no)
PE (1) PE20000945A1 (no)
WO (1) WO2000006564A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6719520B2 (en) 1998-10-08 2004-04-13 Smithkline Beecham Corporation Method and compounds
ATE284387T1 (de) * 1998-10-08 2004-12-15 Smithkline Beecham Plc 3-(3-chloro-4-hydroxyphenylamino)-4-(2- nitrophenyl)-1h-pyrrol-2,5-dion als glykogen synthase kinase-3 inhibitor (gsk-3)
AU6593600A (en) * 1999-08-20 2001-03-19 Rei Asakai Drugs inhibiting cell death
GB0008264D0 (en) * 2000-04-04 2000-05-24 Smithkline Beecham Plc Novel method and compounds
ATE326464T1 (de) 2000-12-08 2006-06-15 Ortho Mcneil Pharm Inc Indazolyl-substituierte pyrrolidin-verbindungen als kinase inhibitoren
US6887868B2 (en) 2001-09-21 2005-05-03 Pharmacia & Upjohn Company Therapeutic 5-HT ligand compounds
AR039209A1 (es) * 2002-04-03 2005-02-09 Novartis Ag Derivados de indolilmaleimida
WO2003104222A1 (en) 2002-06-05 2003-12-18 Janssen Pharmaceutica N.V. Bisindolyl-maleimid derivatives as kinase inhibitors
AU2003240517A1 (en) 2002-06-05 2003-12-22 Janssen Pharmaceutica N.V. Substituted pyrrolines as kinase inhibitors
EP1654255B1 (en) 2003-06-13 2008-08-27 Janssen Pharmaceutica N.V. Substituted indazolyl(indolyl)maleimide derivatives as kinase inhibitors
GB0316232D0 (en) 2003-07-11 2003-08-13 Astrazeneca Ab Therapeutic agents
MX2007005199A (es) 2004-11-01 2007-05-11 Wyeth Corp Indolizinas sustituidas y derivados como agentes del sistema nervioso central.
ZA200706530B (en) * 2005-02-09 2009-01-28 Arqule Inc Meleimide derivatives, pharmaceutical compositions and methods for treatment of cancer
CN101801961B (zh) * 2007-06-22 2014-09-24 艾科尔公司 吡咯烷酮、吡咯烷-2,5-二酮、吡咯烷和硫代琥珀酰亚胺衍生物、组合物以及治疗癌症的方法
CA2690782C (en) 2007-06-22 2016-02-02 Arqule, Inc. Compositions and methods for treatment of cancer
AU2008268613A1 (en) 2007-06-22 2008-12-31 Arqule, Inc. Quinazolinone compounds and methods of use thereof
CN101671329B (zh) * 2009-06-17 2012-11-07 东华大学 3-氨基醇取代的吲哚马来酰亚胺化合物、其制备和应用
CN102344443A (zh) * 2011-07-15 2012-02-08 南开大学 点击化学合成开环马来酰亚胺类化合物及其在治疗疾病中的应用
WO2013029043A1 (en) * 2011-08-25 2013-02-28 Reaction Biology Corp. Selective kinase inhibitors
CN112574163B (zh) * 2021-01-29 2023-04-07 山西省肿瘤研究所 巴西苏木素类天然产物(+)-Brazilin的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4005970A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte maleinimide, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
GB9123396D0 (en) * 1991-11-04 1991-12-18 Hoffmann La Roche A process for the manufacture of substituted maleimides

Also Published As

Publication number Publication date
CA2338866A1 (en) 2000-02-10
PE20000945A1 (es) 2000-09-25
AU4929999A (en) 2000-02-21
NO20010487L (no) 2001-03-28
WO2000006564A1 (fr) 2000-02-10
KR20010085305A (ko) 2001-09-07
HUP0103381A3 (en) 2002-07-29
EP1120414A1 (en) 2001-08-01
HUP0103381A2 (hu) 2002-02-28
BR9912612A (pt) 2001-11-20
CN1320123A (zh) 2001-10-31
IL141080A0 (en) 2002-02-10
ID27510A (id) 2001-04-12

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