NO20044192L - 17alfa-alkyl-17beta-oksy-ostratriener og farmasoytiske preparater - Google Patents

17alfa-alkyl-17beta-oksy-ostratriener og farmasoytiske preparater

Info

Publication number
NO20044192L
NO20044192L NO20044192A NO20044192A NO20044192L NO 20044192 L NO20044192 L NO 20044192L NO 20044192 A NO20044192 A NO 20044192A NO 20044192 A NO20044192 A NO 20044192A NO 20044192 L NO20044192 L NO 20044192L
Authority
NO
Norway
Prior art keywords
ostratrienes
17alpha
17beta
oxy
alkyl
Prior art date
Application number
NO20044192A
Other languages
English (en)
Inventor
Rolf Bohlmann
Orlin Petrov
Nikolaus Heinrich
Jorg Kroll
Jens Hoffmann
Rosemarie Lichtner
Rolf Jautelat
Andreas Reichel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20044192L publication Critical patent/NO20044192L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
NO20044192A 2001-11-27 2004-10-04 17alfa-alkyl-17beta-oksy-ostratriener og farmasoytiske preparater NO20044192L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10159217A DE10159217A1 (de) 2001-11-27 2001-11-27 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
PCT/EP2002/013484 WO2003045972A1 (de) 2001-11-27 2002-11-27 17α-ALKYL-17β-OXY-ESTRATRIENE UND ZWISCHENPRODUKTE ZU DEREN HERSTELLUNG, VERWENDUNG DER 17α-ALKYL-17β-OXY-ESTRATRIENE ZUR HERSTELLUNG VON ARZNEIMITTELN SOWIE PHARMAZEUTISCHE PRÄPARATE

Publications (1)

Publication Number Publication Date
NO20044192L true NO20044192L (no) 2004-10-04

Family

ID=7707804

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20042694A NO326241B1 (no) 2001-11-27 2004-06-25 17 alfa-alkyl-17 beta-oksy-ostratriener og mellomprodukter for fremstilling av disse, anvendelse av 17 alfa-alkyl-17 beta-oksy-ostratrienene til fremstilling av legemidler samt farmasoytiske preparater
NO20044192A NO20044192L (no) 2001-11-27 2004-10-04 17alfa-alkyl-17beta-oksy-ostratriener og farmasoytiske preparater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20042694A NO326241B1 (no) 2001-11-27 2004-06-25 17 alfa-alkyl-17 beta-oksy-ostratriener og mellomprodukter for fremstilling av disse, anvendelse av 17 alfa-alkyl-17 beta-oksy-ostratrienene til fremstilling av legemidler samt farmasoytiske preparater

Country Status (26)

Country Link
US (2) US7018994B2 (no)
EP (2) EP1916254A3 (no)
JP (3) JP2005513039A (no)
KR (1) KR100956912B1 (no)
CN (2) CN1325507C (no)
AR (1) AR037674A1 (no)
AT (1) ATE396198T1 (no)
AU (1) AU2002360949A1 (no)
BR (1) BR0214469A (no)
CA (1) CA2468412C (no)
CY (1) CY1108279T1 (no)
DE (2) DE10159217A1 (no)
DK (1) DK1448591T3 (no)
ES (1) ES2307819T3 (no)
HK (2) HK1077832A1 (no)
IL (2) IL162200A0 (no)
MX (1) MXPA04005015A (no)
NO (2) NO326241B1 (no)
PE (1) PE20030727A1 (no)
PL (1) PL207955B1 (no)
PT (1) PT1448591E (no)
RU (2) RU2285009C2 (no)
TW (1) TWI256891B (no)
UY (1) UY27552A1 (no)
WO (1) WO2003045972A1 (no)
ZA (2) ZA200405029B (no)

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US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
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DE102007049630A1 (de) 2007-10-11 2009-10-29 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
DE102007023614A1 (de) 2007-05-21 2008-11-27 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
AU2008244523B2 (en) 2007-04-23 2012-02-16 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
DE102007032800A1 (de) 2007-07-10 2009-01-15 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
EP2033948A1 (en) * 2007-08-30 2009-03-11 Bayer Schering Pharma Aktiengesellschaft Process for preparing Estrogen-antagonistic 11beta-Fluoro-17alpha-alkylestra-1,3,5 (10)-triene-3, 17-diols having a 7alpha-(xi-Alkylamino-omega-perfluoroalkyl)alkyl side chain and alpha-Alkyl(amino)-omega-perfluoro(alkyl)alkanes and processes for their preparation
DE102007058747A1 (de) 2007-12-05 2009-06-10 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
EP2070942A1 (de) 2007-12-13 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Verfahren zur Aromatisierung von 19-Nor-androst-4-en-3-onen zu Estra-1,3,5(10)-trienen
EP2070941A1 (en) 2007-12-14 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Stereoselective synthesis of selective estrogen receptor down-regulators
EP2070909A1 (de) 2007-12-15 2009-06-17 Bayer Schering Pharma AG Nichtsteroidale Progesteronrezeptor-Modulatoren
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
DE102008057230A1 (de) * 2008-11-11 2010-05-12 Bayer Schering Pharma Aktiengesellschaft Synergistische pharmazeutische Kombination mit einem Estrogenrezeptorantagonisten und einem Progestin
EP2258375A1 (de) * 2009-06-04 2010-12-08 Bayer Schering Pharma Aktiengesellschaft 17B-alkyl-17alpha-oxy-estratriene
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
WO2011037623A1 (en) 2009-09-28 2011-03-31 Intarcia Therapeutics, Inc. Rapid establishment and/or termination of substantial steady-state drug delivery
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007719A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
KR20170127044A (ko) 2010-06-16 2017-11-20 앙도르쉐르슈 인코포레이티드 에스트로겐-관련 질병의 치료 또는 예방 방법
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
DE102011004899A1 (de) 2011-03-01 2012-09-06 Bayer Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
PT2983671T (pt) 2013-04-11 2019-02-25 Bayer Pharma AG Forma farmacêutica de antagonista de recetor de progesterona
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
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RU2750488C1 (ru) * 2020-06-03 2021-06-28 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) 1,2,4-Оксадиазольные производные дезоксихолевой кислоты, обладающие простатопротекторным действием, гипохолестеринемической и противовоспалительной активностями
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Also Published As

Publication number Publication date
ATE396198T1 (de) 2008-06-15
CN1637015A (zh) 2005-07-13
AR037674A1 (es) 2004-12-01
US20060009436A1 (en) 2006-01-12
CA2468412A1 (en) 2003-06-05
TWI256891B (en) 2006-06-21
CA2468412C (en) 2010-01-12
TW200305426A (en) 2003-11-01
JP2005513039A (ja) 2005-05-12
CY1108279T1 (el) 2014-02-12
RU2285009C2 (ru) 2006-10-10
IL162200A0 (en) 2005-11-20
ZA200405029B (en) 2009-07-29
EP1916254A2 (de) 2008-04-30
MXPA04005015A (es) 2005-04-08
RU2006120215A (ru) 2008-01-10
US7538100B2 (en) 2009-05-26
HK1079215A1 (en) 2006-03-31
EP1448591A1 (de) 2004-08-25
KR20040063158A (ko) 2004-07-12
CN100558741C (zh) 2009-11-11
DE10159217A1 (de) 2003-06-05
CN1617879A (zh) 2005-05-18
NO20042694L (no) 2004-07-22
NO326241B1 (no) 2008-10-27
EP1916254A3 (de) 2012-11-14
WO2003045972A1 (de) 2003-06-05
RU2339643C2 (ru) 2008-11-27
ZA200407868B (en) 2005-04-26
KR100956912B1 (ko) 2010-05-11
PE20030727A1 (es) 2003-09-18
UY27552A1 (es) 2003-06-30
JP2005120110A (ja) 2005-05-12
PT1448591E (pt) 2008-09-19
PL207955B1 (pl) 2011-02-28
US7018994B2 (en) 2006-03-28
EP1448591B1 (de) 2008-05-21
JP2006306896A (ja) 2006-11-09
IL162200A (en) 2010-06-30
BR0214469A (pt) 2004-10-13
DK1448591T3 (da) 2008-09-29
HK1077832A1 (en) 2006-02-24
AU2002360949A1 (en) 2003-06-10
CN1325507C (zh) 2007-07-11
RU2004119437A (ru) 2005-07-10
ES2307819T3 (es) 2008-12-01
DE50212302D1 (de) 2008-07-03
PL369171A1 (en) 2005-04-18
US20030191099A1 (en) 2003-10-09
JP4335820B2 (ja) 2009-09-30

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