DK1849468T3 - Farmaceutisk sammensætning omfattende roflumilast og levocetirizin - Google Patents

Farmaceutisk sammensætning omfattende roflumilast og levocetirizin

Info

Publication number
DK1849468T3
DK1849468T3 DK07112823.5T DK07112823T DK1849468T3 DK 1849468 T3 DK1849468 T3 DK 1849468T3 DK 07112823 T DK07112823 T DK 07112823T DK 1849468 T3 DK1849468 T3 DK 1849468T3
Authority
DK
Denmark
Prior art keywords
levocetirizine
roflumilast
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
DK07112823.5T
Other languages
English (en)
Inventor
Christian Weimar
Daniela Bundschuh
Rolf Beume
Stefan-Lutz Wollin
Original Assignee
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Gmbh filed Critical Takeda Gmbh
Application granted granted Critical
Publication of DK1849468T3 publication Critical patent/DK1849468T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/423Oxazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK07112823.5T 2002-03-06 2003-02-25 Farmaceutisk sammensætning omfattende roflumilast og levocetirizin DK1849468T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02004987 2002-03-06
EP03708130A EP1482938B1 (en) 2002-03-06 2003-02-25 Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist

Publications (1)

Publication Number Publication Date
DK1849468T3 true DK1849468T3 (da) 2013-02-04

Family

ID=27771841

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03708130T DK1482938T3 (da) 2002-03-06 2003-02-25 Farmaceutisk præparat af en PDE4 eller en PDE3/4 inhibitor og en histaminreceptorantagonist
DK07112823.5T DK1849468T3 (da) 2002-03-06 2003-02-25 Farmaceutisk sammensætning omfattende roflumilast og levocetirizin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK03708130T DK1482938T3 (da) 2002-03-06 2003-02-25 Farmaceutisk præparat af en PDE4 eller en PDE3/4 inhibitor og en histaminreceptorantagonist

Country Status (32)

Country Link
US (1) US20050112069A1 (da)
EP (2) EP1849468B1 (da)
JP (1) JP5150034B2 (da)
KR (1) KR20040095255A (da)
CN (1) CN101257904A (da)
AR (1) AR038858A1 (da)
AT (1) ATE369134T1 (da)
AU (1) AU2003212268B2 (da)
BR (1) BR0308220A (da)
CA (1) CA2478612C (da)
CO (1) CO5611148A2 (da)
CY (2) CY1106927T1 (da)
DE (1) DE60315426T2 (da)
DK (2) DK1482938T3 (da)
EA (2) EA010886B1 (da)
ES (2) ES2400670T3 (da)
HK (1) HK1071308A1 (da)
HR (1) HRP20040909B1 (da)
IL (1) IL163336A (da)
IS (2) IS2536B (da)
MX (1) MXPA04008460A (da)
NO (1) NO335254B1 (da)
NZ (1) NZ535611A (da)
PL (1) PL211574B1 (da)
PT (2) PT1849468E (da)
RS (1) RS51018B (da)
SG (1) SG160197A1 (da)
SI (2) SI1482938T1 (da)
TW (1) TWI347845B (da)
UA (1) UA80117C2 (da)
WO (1) WO2003074055A1 (da)
ZA (1) ZA200407104B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ568694A (en) * 2005-11-09 2011-09-30 Zalicus Inc Method, compositions, and kits for the treatment of medical conditions
EP2091538B1 (en) * 2006-12-20 2010-03-03 Glaxo Group Limited 4-benzyl-1(2h)-phthalazinones as h1 receptor antagonists
TW200902025A (en) * 2007-04-11 2009-01-16 Alcon Res Ltd Use of an inhibitor of TNF α plus an antihistamine to treat allergic rhinitis and allergic conjunctivitis
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
US8877816B2 (en) 2007-11-21 2014-11-04 Decode Genetics Ehf 4-(or 5-) substituted catechol derivatives
KR20090061972A (ko) * 2007-12-12 2009-06-17 한미약품 주식회사 베포타스틴 p-톨루엔술폰산염의 결정형, 이의 제조방법 및이를 포함하는 약학 조성물
RS55624B1 (sr) 2011-02-07 2017-06-30 Scipharm Sàrl Nova kompozicija za lečenje cistične fibroze
KR102226833B1 (ko) * 2013-06-28 2021-03-12 한미약품 주식회사 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형
JP2017525721A (ja) * 2014-08-26 2017-09-07 ファンダシオン パラ ラ インベスティガシオン メディカ アプリカダFundacion Para La Investigasion Medica Aplicada 認知欠損または認知障害に伴って進行する神経障害のおよび神経変性疾患の処置および予防のための製品
AU2015330490B2 (en) 2014-10-09 2018-08-09 Guangdong Raynovent Biotech Co., Ltd. Hydroxyl purine compounds and applications thereof
CN109956947A (zh) * 2017-12-25 2019-07-02 江苏恒瑞医药股份有限公司 一种cns抑制剂的新晶型、制备方法及用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2847693A1 (de) * 1978-11-03 1980-05-22 Hoechst Ag Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
CZ290266B6 (cs) * 1993-07-02 2002-06-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituované benzamidy, způsob jejich výroby a farmaceutické prostředky s jejich obsahem
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
US5990147A (en) * 1997-11-07 1999-11-23 Schering Corporation H3 receptor ligands of the phenyl-alkyl-imidazoles type
BR9804993A (pt) * 1998-11-10 2000-06-06 Panacea Biotec Ltd Composição antialérgica e antiinflamatória
US6174878B1 (en) * 1999-08-31 2001-01-16 Alcon Laboratories, Inc. Topical use of kappa opioid agonists to treat otic pain
IL148807A0 (en) * 1999-10-25 2002-09-12 Byk Gulden Lomberg Chem Fab Tetrahydrothiopyran derivatives and pharmaceutical compositions containing the same
US7585847B2 (en) * 2000-02-03 2009-09-08 Coley Pharmaceutical Group, Inc. Immunostimulatory nucleic acids for the treatment of asthma and allergy
GB0115181D0 (en) * 2001-06-20 2001-08-15 Glaxo Group Ltd Novel use

Also Published As

Publication number Publication date
MXPA04008460A (es) 2004-12-06
AR038858A1 (es) 2005-01-26
CY1106927T1 (el) 2012-09-26
KR20040095255A (ko) 2004-11-12
ATE369134T1 (de) 2007-08-15
PL211574B1 (pl) 2012-05-31
SI1482938T1 (sl) 2007-12-31
HRP20040909A2 (en) 2005-08-31
UA80117C2 (uk) 2007-08-27
NO335254B1 (no) 2014-10-27
ES2400670T3 (es) 2013-04-11
NO20044230L (no) 2004-12-06
EA007903B1 (ru) 2007-02-27
SI1849468T1 (sl) 2013-03-29
AU2003212268B2 (en) 2008-09-11
DE60315426T2 (de) 2008-07-03
CA2478612A1 (en) 2003-09-12
TW200306855A (en) 2003-12-01
RS78004A (en) 2006-12-15
EA010886B1 (ru) 2008-12-30
EP1849468A2 (en) 2007-10-31
JP2005524666A (ja) 2005-08-18
PL371056A1 (en) 2005-06-13
ZA200407104B (en) 2006-12-27
US20050112069A1 (en) 2005-05-26
IS2536B (is) 2009-08-15
DK1482938T3 (da) 2007-12-03
EP1482938A1 (en) 2004-12-08
HRP20040909B1 (en) 2012-11-30
RS51018B (sr) 2010-10-31
SG160197A1 (en) 2010-04-29
BR0308220A (pt) 2005-01-04
EA200401137A1 (ru) 2005-04-28
HK1071308A1 (en) 2005-07-15
EP1482938B1 (en) 2007-08-08
ES2291618T3 (es) 2008-03-01
NZ535611A (en) 2006-03-31
EA200601592A1 (ru) 2006-12-29
DE60315426D1 (de) 2007-09-20
AU2003212268A1 (en) 2003-09-16
JP5150034B2 (ja) 2013-02-20
WO2003074055A1 (en) 2003-09-12
IL163336A (en) 2009-02-11
EP1849468A3 (en) 2007-11-07
CA2478612C (en) 2013-12-10
CO5611148A2 (es) 2006-02-28
TWI347845B (en) 2011-09-01
CN101257904A (zh) 2008-09-03
PT1482938E (pt) 2007-11-15
PT1849468E (pt) 2013-02-27
IS8760A (is) 2008-09-04
EP1849468B1 (en) 2012-12-05
CY1113894T1 (el) 2016-07-27
IS7438A (is) 2004-09-03

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