IS7438A - Lyfjablanda úr PDE4 eða PDE3/4 tálma og histamínviðtakamótlyfi - Google Patents

Lyfjablanda úr PDE4 eða PDE3/4 tálma og histamínviðtakamótlyfi

Info

Publication number
IS7438A
IS7438A IS7438A IS7438A IS7438A IS 7438 A IS7438 A IS 7438A IS 7438 A IS7438 A IS 7438A IS 7438 A IS7438 A IS 7438A IS 7438 A IS7438 A IS 7438A
Authority
IS
Iceland
Prior art keywords
pde3
pde4
inhibitor
receptor antagonist
histamine receptor
Prior art date
Application number
IS7438A
Other languages
English (en)
Other versions
IS2536B (is
Inventor
Beume Rolf
Bundschuh Daniela
Weimar Christian
Wollin Stefan-Lutz
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of IS7438A publication Critical patent/IS7438A/is
Publication of IS2536B publication Critical patent/IS2536B/is

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/423Oxazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IS7438A 2002-03-06 2004-09-03 Lyfjablanda úr PDE4 eða PDE3/4 tálma og histamínviðtakamótlyfi IS2536B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02004987 2002-03-06
PCT/EP2003/001876 WO2003074055A1 (en) 2002-03-06 2003-02-25 Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist

Publications (2)

Publication Number Publication Date
IS7438A true IS7438A (is) 2004-09-03
IS2536B IS2536B (is) 2009-08-15

Family

ID=27771841

Family Applications (2)

Application Number Title Priority Date Filing Date
IS7438A IS2536B (is) 2002-03-06 2004-09-03 Lyfjablanda úr PDE4 eða PDE3/4 tálma og histamínviðtakamótlyfi
IS8760A IS8760A (is) 2002-03-06 2008-09-04 Lyfjablanda úr pde4 eða pde3/4 tálma og histamínviðtakamótlyfi

Family Applications After (1)

Application Number Title Priority Date Filing Date
IS8760A IS8760A (is) 2002-03-06 2008-09-04 Lyfjablanda úr pde4 eða pde3/4 tálma og histamínviðtakamótlyfi

Country Status (32)

Country Link
US (1) US20050112069A1 (is)
EP (2) EP1849468B1 (is)
JP (1) JP5150034B2 (is)
KR (1) KR20040095255A (is)
CN (1) CN101257904A (is)
AR (1) AR038858A1 (is)
AT (1) ATE369134T1 (is)
AU (1) AU2003212268B2 (is)
BR (1) BR0308220A (is)
CA (1) CA2478612C (is)
CO (1) CO5611148A2 (is)
CY (2) CY1106927T1 (is)
DE (1) DE60315426T2 (is)
DK (2) DK1482938T3 (is)
EA (2) EA007903B1 (is)
ES (2) ES2400670T3 (is)
HK (1) HK1071308A1 (is)
HR (1) HRP20040909B1 (is)
IL (1) IL163336A (is)
IS (2) IS2536B (is)
MX (1) MXPA04008460A (is)
NO (1) NO335254B1 (is)
NZ (1) NZ535611A (is)
PL (1) PL211574B1 (is)
PT (2) PT1482938E (is)
RS (1) RS51018B (is)
SG (1) SG160197A1 (is)
SI (2) SI1482938T1 (is)
TW (1) TWI347845B (is)
UA (1) UA80117C2 (is)
WO (1) WO2003074055A1 (is)
ZA (1) ZA200407104B (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101355876B (zh) 2005-11-09 2012-09-05 康宾纳特克斯公司 一种适用于眼部给药的组合物
JP2010513393A (ja) * 2006-12-20 2010-04-30 グラクソ グループ リミテッド H1受容体アンタゴニストとしての4−ベンジル−l(2h)−フタラジノン
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
AR066016A1 (es) * 2007-04-11 2009-07-15 Alcon Res Ltd Uso de un inhibidor del tnf alfa junto con una antihistamina para tratar la rinitis alergica y la conjuntivitis alergica
US8877816B2 (en) 2007-11-21 2014-11-04 Decode Genetics Ehf 4-(or 5-) substituted catechol derivatives
KR20090061972A (ko) * 2007-12-12 2009-06-17 한미약품 주식회사 베포타스틴 p-톨루엔술폰산염의 결정형, 이의 제조방법 및이를 포함하는 약학 조성물
LT2672957T (lt) 2011-02-07 2017-02-10 Scipharm Sarl Naujoji kompozicija, skirta cistinės fibrozės gydymui
KR102226833B1 (ko) * 2013-06-28 2021-03-12 한미약품 주식회사 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형
US20170231931A1 (en) * 2014-08-26 2017-08-17 Fundación Para La Investigación Médica Aplicada Products for the treatment and prevention of neurological disorders coursing with a cognition deficit or impairment, and of neurodegenerative diseases
RU2673458C1 (ru) 2014-10-09 2018-11-27 Гуандун Чжуншэн Фармасьютикал Ко., Лтд Гидроксипуриновые соединения и пути их применения
CN109956947A (zh) * 2017-12-25 2019-07-02 江苏恒瑞医药股份有限公司 一种cns抑制剂的新晶型、制备方法及用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2847693A1 (de) * 1978-11-03 1980-05-22 Hoechst Ag Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
DK0706513T3 (da) * 1993-07-02 2002-09-09 Altana Pharma Ag Fluoralkoxysubstituerede benzamider og anvendelse deraf som cyklisk-nukleotid phosphodiesteraseinhibitorer
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
US5990147A (en) * 1997-11-07 1999-11-23 Schering Corporation H3 receptor ligands of the phenyl-alkyl-imidazoles type
BR9804993A (pt) * 1998-11-10 2000-06-06 Panacea Biotec Ltd Composição antialérgica e antiinflamatória
US6174878B1 (en) * 1999-08-31 2001-01-16 Alcon Laboratories, Inc. Topical use of kappa opioid agonists to treat otic pain
TR200201128T2 (tr) * 1999-10-25 2002-08-21 Byk Gulden Lomberg Chemische Fabrik Gmbh PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
US7585847B2 (en) * 2000-02-03 2009-09-08 Coley Pharmaceutical Group, Inc. Immunostimulatory nucleic acids for the treatment of asthma and allergy
GB0115181D0 (en) * 2001-06-20 2001-08-15 Glaxo Group Ltd Novel use

Also Published As

Publication number Publication date
EP1482938A1 (en) 2004-12-08
EA200401137A1 (ru) 2005-04-28
UA80117C2 (uk) 2007-08-27
EA007903B1 (ru) 2007-02-27
NO335254B1 (no) 2014-10-27
PT1482938E (pt) 2007-11-15
DE60315426T2 (de) 2008-07-03
EP1482938B1 (en) 2007-08-08
EA010886B1 (ru) 2008-12-30
US20050112069A1 (en) 2005-05-26
EP1849468B1 (en) 2012-12-05
CO5611148A2 (es) 2006-02-28
HRP20040909B1 (en) 2012-11-30
WO2003074055A1 (en) 2003-09-12
JP5150034B2 (ja) 2013-02-20
CN101257904A (zh) 2008-09-03
TW200306855A (en) 2003-12-01
HK1071308A1 (en) 2005-07-15
MXPA04008460A (es) 2004-12-06
NO20044230L (no) 2004-12-06
RS51018B (sr) 2010-10-31
ES2400670T3 (es) 2013-04-11
CY1106927T1 (el) 2012-09-26
BR0308220A (pt) 2005-01-04
AR038858A1 (es) 2005-01-26
ATE369134T1 (de) 2007-08-15
PL371056A1 (en) 2005-06-13
SI1482938T1 (sl) 2007-12-31
IS8760A (is) 2008-09-04
AU2003212268B2 (en) 2008-09-11
IL163336A (en) 2009-02-11
HRP20040909A2 (en) 2005-08-31
NZ535611A (en) 2006-03-31
DK1482938T3 (da) 2007-12-03
PL211574B1 (pl) 2012-05-31
IS2536B (is) 2009-08-15
RS78004A (en) 2006-12-15
JP2005524666A (ja) 2005-08-18
EP1849468A3 (en) 2007-11-07
ZA200407104B (en) 2006-12-27
CY1113894T1 (el) 2016-07-27
EA200601592A1 (ru) 2006-12-29
CA2478612A1 (en) 2003-09-12
EP1849468A2 (en) 2007-10-31
ES2291618T3 (es) 2008-03-01
SI1849468T1 (sl) 2013-03-29
CA2478612C (en) 2013-12-10
AU2003212268A1 (en) 2003-09-16
SG160197A1 (en) 2010-04-29
DE60315426D1 (de) 2007-09-20
PT1849468E (pt) 2013-02-27
KR20040095255A (ko) 2004-11-12
TWI347845B (en) 2011-09-01
DK1849468T3 (da) 2013-02-04

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