PT1849468E - Composição farmacêutica compreendendo roflumilaste levocetirizina - Google Patents

Composição farmacêutica compreendendo roflumilaste levocetirizina

Info

Publication number
PT1849468E
PT1849468E PT71128235T PT07112823T PT1849468E PT 1849468 E PT1849468 E PT 1849468E PT 71128235 T PT71128235 T PT 71128235T PT 07112823 T PT07112823 T PT 07112823T PT 1849468 E PT1849468 E PT 1849468E
Authority
PT
Portugal
Prior art keywords
levocetirizine
roflumilast
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
PT71128235T
Other languages
English (en)
Inventor
Rolf Beume
Daniela Bundschuh
Christian Weimar
Stefan-Lutz Wollin
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of PT1849468E publication Critical patent/PT1849468E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/423Oxazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PT71128235T 2002-03-06 2003-02-25 Composição farmacêutica compreendendo roflumilaste levocetirizina PT1849468E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02004987 2002-03-06

Publications (1)

Publication Number Publication Date
PT1849468E true PT1849468E (pt) 2013-02-27

Family

ID=27771841

Family Applications (2)

Application Number Title Priority Date Filing Date
PT03708130T PT1482938E (pt) 2002-03-06 2003-02-25 Composição farmacêutica de um inibidor da pde4 ou de um inibidor da pde3/4 e um antagonista dos receptores histamínicos
PT71128235T PT1849468E (pt) 2002-03-06 2003-02-25 Composição farmacêutica compreendendo roflumilaste levocetirizina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT03708130T PT1482938E (pt) 2002-03-06 2003-02-25 Composição farmacêutica de um inibidor da pde4 ou de um inibidor da pde3/4 e um antagonista dos receptores histamínicos

Country Status (32)

Country Link
US (1) US20050112069A1 (pt)
EP (2) EP1849468B1 (pt)
JP (1) JP5150034B2 (pt)
KR (1) KR20040095255A (pt)
CN (1) CN101257904A (pt)
AR (1) AR038858A1 (pt)
AT (1) ATE369134T1 (pt)
AU (1) AU2003212268B2 (pt)
BR (1) BR0308220A (pt)
CA (1) CA2478612C (pt)
CO (1) CO5611148A2 (pt)
CY (2) CY1106927T1 (pt)
DE (1) DE60315426T2 (pt)
DK (2) DK1849468T3 (pt)
EA (2) EA007903B1 (pt)
ES (2) ES2400670T3 (pt)
HK (1) HK1071308A1 (pt)
HR (1) HRP20040909B1 (pt)
IL (1) IL163336A (pt)
IS (2) IS2536B (pt)
MX (1) MXPA04008460A (pt)
NO (1) NO335254B1 (pt)
NZ (1) NZ535611A (pt)
PL (1) PL211574B1 (pt)
PT (2) PT1482938E (pt)
RS (1) RS51018B (pt)
SG (1) SG160197A1 (pt)
SI (2) SI1849468T1 (pt)
TW (1) TWI347845B (pt)
UA (1) UA80117C2 (pt)
WO (1) WO2003074055A1 (pt)
ZA (1) ZA200407104B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1956906A4 (en) * 2005-11-09 2009-12-30 Combinatorx Inc METHODS, COMPOSITIONS AND KITS FOR THE TREATMENT OF PATHOLOGIES
ATE459358T1 (de) * 2006-12-20 2010-03-15 Glaxo Group Ltd 4-benzyl-1(2h)-phthalazinone als h1-rezeptor- antagonisten
RU2009141592A (ru) * 2007-04-11 2011-05-20 Алькон Рисерч, Лтд. (Us) ПРИМЕНЕНИЕ ИНГИБИТОРА TNFα В СОЧЕТАНИИ С АНТИГИСТАМИННЫМ СРЕДСТВОМ ДЛЯ ЛЕЧЕНИЯ АЛЛЕРГИЧЕСКОГО РИНИТА И АЛЛЕРГИЧЕСКОГО КОНЪЮНКТИВИТА
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
WO2009067597A1 (en) * 2007-11-21 2009-05-28 Decode Genetics Ehf 4- (or 5-) substituted catechol derivatives
KR20090061972A (ko) * 2007-12-12 2009-06-17 한미약품 주식회사 베포타스틴 p-톨루엔술폰산염의 결정형, 이의 제조방법 및이를 포함하는 약학 조성물
AU2012215606B2 (en) 2011-02-07 2016-12-22 Scipharm Sarl Novel composition for the treatment of cystic fibrosis
KR102226833B1 (ko) * 2013-06-28 2021-03-12 한미약품 주식회사 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형
CA2993462A1 (en) * 2014-08-26 2016-03-03 Fundacion Para La Investigacion Medica Aplicada Products for the treatment and prevention of neurological disorders coursing with a cognition deficit or impairment, and of neurodegenerative diseases
BR112017007194B1 (pt) 2014-10-09 2023-11-07 Guangdong Raynovent Biotech Co., Ltd Compostos de hidroxil purina e uso dos mesmos
CN109956947A (zh) * 2017-12-25 2019-07-02 江苏恒瑞医药股份有限公司 一种cns抑制剂的新晶型、制备方法及用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2847693A1 (de) * 1978-11-03 1980-05-22 Hoechst Ag Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
ES2176252T3 (es) * 1993-07-02 2002-12-01 Altana Pharma Ag Benzamidas sustituidas con fluoro-alcoxi y su utilizacion como agentes inhibidores de fosfodiesterasas de nucleotidos ciclicos.
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
US5990147A (en) * 1997-11-07 1999-11-23 Schering Corporation H3 receptor ligands of the phenyl-alkyl-imidazoles type
BR9804993A (pt) * 1998-11-10 2000-06-06 Panacea Biotec Ltd Composição antialérgica e antiinflamatória
US6174878B1 (en) * 1999-08-31 2001-01-16 Alcon Laboratories, Inc. Topical use of kappa opioid agonists to treat otic pain
CZ20021457A3 (cs) * 1999-10-25 2002-07-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydrothiopyranové sloučeniny
US7585847B2 (en) * 2000-02-03 2009-09-08 Coley Pharmaceutical Group, Inc. Immunostimulatory nucleic acids for the treatment of asthma and allergy
GB0115181D0 (en) * 2001-06-20 2001-08-15 Glaxo Group Ltd Novel use

Also Published As

Publication number Publication date
EA010886B1 (ru) 2008-12-30
PT1482938E (pt) 2007-11-15
NO20044230L (no) 2004-12-06
ATE369134T1 (de) 2007-08-15
AR038858A1 (es) 2005-01-26
SG160197A1 (en) 2010-04-29
DE60315426T2 (de) 2008-07-03
SI1482938T1 (sl) 2007-12-31
ES2291618T3 (es) 2008-03-01
RS51018B (sr) 2010-10-31
JP2005524666A (ja) 2005-08-18
CA2478612A1 (en) 2003-09-12
KR20040095255A (ko) 2004-11-12
DK1849468T3 (da) 2013-02-04
IS7438A (is) 2004-09-03
DE60315426D1 (de) 2007-09-20
SI1849468T1 (sl) 2013-03-29
AU2003212268A1 (en) 2003-09-16
EP1482938A1 (en) 2004-12-08
US20050112069A1 (en) 2005-05-26
HRP20040909A2 (en) 2005-08-31
PL371056A1 (en) 2005-06-13
CY1106927T1 (el) 2012-09-26
EP1849468B1 (en) 2012-12-05
ZA200407104B (en) 2006-12-27
CA2478612C (en) 2013-12-10
AU2003212268B2 (en) 2008-09-11
IS2536B (is) 2009-08-15
EP1849468A2 (en) 2007-10-31
CY1113894T1 (el) 2016-07-27
HK1071308A1 (en) 2005-07-15
DK1482938T3 (da) 2007-12-03
CN101257904A (zh) 2008-09-03
TW200306855A (en) 2003-12-01
TWI347845B (en) 2011-09-01
CO5611148A2 (es) 2006-02-28
IL163336A (en) 2009-02-11
EP1482938B1 (en) 2007-08-08
PL211574B1 (pl) 2012-05-31
HRP20040909B1 (en) 2012-11-30
MXPA04008460A (es) 2004-12-06
EA200601592A1 (ru) 2006-12-29
JP5150034B2 (ja) 2013-02-20
NZ535611A (en) 2006-03-31
EP1849468A3 (en) 2007-11-07
EA200401137A1 (ru) 2005-04-28
RS78004A (en) 2006-12-15
WO2003074055A1 (en) 2003-09-12
ES2400670T3 (es) 2013-04-11
BR0308220A (pt) 2005-01-04
IS8760A (is) 2008-09-04
NO335254B1 (no) 2014-10-27
UA80117C2 (uk) 2007-08-27
EA007903B1 (ru) 2007-02-27

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