NO993731L - Pyrrolopyrazolopyrimidin-forbindelse og medisin omfattende denne - Google Patents

Pyrrolopyrazolopyrimidin-forbindelse og medisin omfattende denne

Info

Publication number
NO993731L
NO993731L NO993731A NO993731A NO993731L NO 993731 L NO993731 L NO 993731L NO 993731 A NO993731 A NO 993731A NO 993731 A NO993731 A NO 993731A NO 993731 L NO993731 L NO 993731L
Authority
NO
Norway
Prior art keywords
medicine
pyrrolopyrazolopyrimidine
compound
pyrrolopyrazolopyrimidine compound
Prior art date
Application number
NO993731A
Other languages
English (en)
Other versions
NO314404B1 (no
NO993731D0 (no
Inventor
Takayuki Namiki
Masayuki Yuasa
Takako Takakuwa
Satoshi Ichinomiya
Yukio Kawazu
Kenichi Kishii
Norio Funayama
Mariko Harada
Kyoko Taneda
Naoki Hiyama
Tomoaki Yahiro
Mayumi Sugio
Masashi Tamai
Original Assignee
Pola Chem Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Chem Ind Inc filed Critical Pola Chem Ind Inc
Publication of NO993731D0 publication Critical patent/NO993731D0/no
Publication of NO993731L publication Critical patent/NO993731L/no
Publication of NO314404B1 publication Critical patent/NO314404B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19993731A 1997-02-03 1999-08-02 Pyrrolopyrazolopyrimidin-forbindelser og medisin omfattende denne og fremgangsmåte for fremstilling derav NO314404B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9020387A JPH10218881A (ja) 1997-02-03 1997-02-03 新規なピロロピラゾロピリミジン誘導体
PCT/JP1998/000315 WO1998033799A1 (en) 1997-02-03 1998-01-27 Pyrrolopyrazolopyrimidine compound and medicine comprising the same

Publications (3)

Publication Number Publication Date
NO993731D0 NO993731D0 (no) 1999-08-02
NO993731L true NO993731L (no) 1999-09-22
NO314404B1 NO314404B1 (no) 2003-03-17

Family

ID=12025624

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993731A NO314404B1 (no) 1997-02-03 1999-08-02 Pyrrolopyrazolopyrimidin-forbindelser og medisin omfattende denne og fremgangsmåte for fremstilling derav

Country Status (7)

Country Link
US (2) US5942515A (no)
EP (1) EP1021447A1 (no)
JP (1) JPH10218881A (no)
AU (1) AU725356B2 (no)
CA (1) CA2228360A1 (no)
NO (1) NO314404B1 (no)
WO (1) WO1998033799A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4192250B2 (ja) * 1997-02-14 2008-12-10 株式会社ポーラファルマ 呼吸器疾患治療・予防用医薬
US6329382B1 (en) 1997-02-14 2001-12-11 Pola Chemical Industries, Inc. Pyrrolo[3,2-e]pyrazolo[1,5-a]pyrimidine remedies/preventives for respiratory diseases
TWI271406B (en) 1999-12-13 2007-01-21 Eisai Co Ltd Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same
DE10012861C2 (de) * 2000-03-16 2002-07-11 Gsf Forschungszentrum Umwelt Rekombinante HHV8-DNA
US7425559B2 (en) 2001-07-13 2008-09-16 Btg International Limited Medicine containing pyrimidine derivative
US7329668B2 (en) 2003-02-25 2008-02-12 Bristol-Myers Squibb Company Pyrazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
MX2007008999A (es) * 2005-02-16 2007-09-18 Basf Ag 5-alcoxialquil-6-alquil-7-amino-azolopirimidinas, un procedimiento para su obtencion y el uso de las mismas para combatir hongos nocivos, asi como productos que las contienen.
CN102007133B (zh) 2008-04-15 2013-06-12 卫材R&D管理有限公司 3-苯基吡唑并[5,1-b]噻唑化合物
US20130225819A1 (en) * 2010-08-18 2013-08-29 Massachusetts Institute Of Technology Use of azides in synthesis
WO2012027239A1 (en) * 2010-08-23 2012-03-01 Schering Corporation NOVEL PYRAZOLO[1,5-a]PYRROLO[3,2-e]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
EP2723746A1 (en) 2011-06-22 2014-04-30 Vertex Pharmaceuticals Inc. Compounds useful as inhibitors of atr kinase
CN107501275B (zh) 2012-12-07 2019-11-22 沃泰克斯药物股份有限公司 可用作atr激酶抑制剂的化合物
EP2970286A1 (en) 2013-03-15 2016-01-20 Vertex Pharmaceuticals Inc. Fused pyrazolopyrimidine derivatives useful as inhibitors of atr kinase
WO2014143242A1 (en) 2013-03-15 2014-09-18 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of atr kinase
EP2970289A1 (en) 2013-03-15 2016-01-20 Vertex Pharmaceuticals Inc. Compounds useful as inhibitors of atr kinase
RU2720408C2 (ru) 2013-12-06 2020-04-29 Вертекс Фармасьютикалз Инкорпорейтед Способ получения ингибиторов atr киназы (варианты)
AU2015271030B2 (en) 2014-06-05 2019-05-16 Vertex Pharmaceuticals Incorporated Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo [1,5-a] pyrimidin-3-carboxamide compound useful as ATR kinase inhibitor, the preparation of said compound and different solid forms thereof
ES2733847T3 (es) 2014-06-17 2019-12-03 Vertex Pharma Método para tratar cáncer usando una combinación de inhibidores de CHK1 y ATR
WO2017059357A1 (en) 2015-09-30 2017-04-06 Vertex Pharmaceuticals Incorporated Method for treating cancer using a combination of dna damaging agents and atr inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0276880A (ja) * 1988-06-16 1990-03-16 Sankyo Co Ltd 悪液質改善治療剤
CA1330079C (en) * 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
DK69592A (da) * 1992-05-26 1993-11-27 Eskofot As Apparat til eksponering og fremkaldelse af lysfoelsomt materiale, fortrinsvis offsetplader

Also Published As

Publication number Publication date
WO1998033799A1 (en) 1998-08-06
US6057330A (en) 2000-05-02
NO314404B1 (no) 2003-03-17
AU5577798A (en) 1998-08-25
CA2228360A1 (en) 1998-08-03
JPH10218881A (ja) 1998-08-18
US5942515A (en) 1999-08-24
AU725356B2 (en) 2000-10-12
NO993731D0 (no) 1999-08-02
EP1021447A1 (en) 2000-07-26

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Legal Events

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