ATE255409T1 - Cisplatinhaltige mikrogranulate - Google Patents

Cisplatinhaltige mikrogranulate

Info

Publication number
ATE255409T1
ATE255409T1 AT98908157T AT98908157T ATE255409T1 AT E255409 T1 ATE255409 T1 AT E255409T1 AT 98908157 T AT98908157 T AT 98908157T AT 98908157 T AT98908157 T AT 98908157T AT E255409 T1 ATE255409 T1 AT E255409T1
Authority
AT
Austria
Prior art keywords
cisplates
microgranules containing
microgranules
containing cisplates
Prior art date
Application number
AT98908157T
Other languages
English (en)
Inventor
Patrice Debregeas
Gerard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm Lab Prod Ethiques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Lab Prod Ethiques filed Critical Ethypharm Lab Prod Ethiques
Application granted granted Critical
Publication of ATE255409T1 publication Critical patent/ATE255409T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98908157T 1997-02-11 1998-02-10 Cisplatinhaltige mikrogranulate ATE255409T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9701545A FR2759293B1 (fr) 1997-02-11 1997-02-11 Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
PCT/FR1998/000251 WO1998034599A1 (fr) 1997-02-11 1998-02-10 Microgranules contenant du cisplatine

Publications (1)

Publication Number Publication Date
ATE255409T1 true ATE255409T1 (de) 2003-12-15

Family

ID=9503556

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98908157T ATE255409T1 (de) 1997-02-11 1998-02-10 Cisplatinhaltige mikrogranulate

Country Status (24)

Country Link
US (2) US6458389B1 (de)
EP (1) EP0971702B1 (de)
JP (1) JP4549445B2 (de)
KR (1) KR100471672B1 (de)
AR (1) AR011133A1 (de)
AT (1) ATE255409T1 (de)
BG (1) BG64247B1 (de)
BR (1) BR9807319A (de)
CA (1) CA2282082C (de)
DE (1) DE69820239T2 (de)
DK (1) DK0971702T3 (de)
EA (1) EA001760B1 (de)
ES (1) ES2210726T3 (de)
FR (1) FR2759293B1 (de)
HU (1) HU225425B1 (de)
IL (1) IL131326A (de)
IN (1) IN187998B (de)
NO (1) NO323230B1 (de)
NZ (1) NZ337216A (de)
PL (1) PL191631B1 (de)
PT (1) PT971702E (de)
TW (1) TW561055B (de)
WO (1) WO1998034599A1 (de)
ZA (1) ZA981123B (de)

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US20050096304A1 (en) * 1998-09-08 2005-05-05 David White Method of treating cancer using dithiocarbamate derivatives
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
EP1178778B1 (de) * 1999-05-17 2006-03-01 D.B.F. Pflanzenmaterial enthaltendes granulat und verfahren zur herstellung
CN1874764B (zh) * 2003-10-10 2012-08-01 埃法尔姆公司 含有银杏提取物的持续释放微粒及其制备方法
FR2861990B1 (fr) * 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
KR20070084325A (ko) * 2004-11-18 2007-08-24 브리스톨-마이어스 스큅 컴퍼니 익사베필론을 포함하는 장용성 코팅된 비드 및 그의 제조방법
US20080069901A1 (en) * 2004-12-10 2008-03-20 Tmrc Co. , Ltd. Therapeutic Agent for Metastatic Cancer and Cancer Metastasis Inhibitor
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
CN101801356B (zh) * 2007-09-21 2016-10-19 赢创罗姆有限公司 耐受乙醇影响的非阿片类的pH依赖性受控释放的药物组合物
SI2187876T1 (sl) * 2007-09-21 2012-12-31 Evonik Roehm Gmbh Od pH odvisen opioidni farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanola
KR20100103565A (ko) * 2008-01-10 2010-09-27 에보니크 룀 게엠베하 촉진되고 조절된 활성 물질 방출을 갖는 코팅된 제약학적 또는 건강기능성 제제
PL2230932T3 (pl) * 2008-01-10 2017-09-29 Evonik Röhm Gmbh Powlekany preparat farmaceutyczny lub nutraceutyczny o zwiększonym uwalnianiu substancji aktywnej w jelicie grubym
DK177529B1 (en) * 2009-10-23 2013-09-08 Bio Bedst Aps Liposomes with improved storage stability
CA2688202C (en) * 2009-12-11 2012-11-13 Bj Services Company Viscoelastic fluids containing hydroxyethyl cellulose
EP2371356B1 (de) * 2010-03-12 2012-12-19 Phoeme GmbH Pharmazeutische Mehrfachpartikelformulierung zur Kolonabsorption
US8070047B1 (en) * 2010-12-02 2011-12-06 Rohm And Haas Electronic Materials Llc Flux composition and method of soldering
WO2014039533A2 (en) 2012-09-04 2014-03-13 Eleison Pharmaceuticals, Llc Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin
JP6487534B2 (ja) 2014-09-05 2019-03-20 シンビオミックス セラピューティクス、エルエルシー 細菌性膣炎の治療に使用するためのセクニダゾール
WO2016169042A1 (en) * 2015-04-24 2016-10-27 Genedia Biotech Co. Ltd. Combination therapies for bladder cancer
WO2016196653A1 (en) * 2015-06-01 2016-12-08 Symbiomix Therapeutics, Llc Novel nitroimidazole formulations and uses thereof
EP3791859A1 (de) 2015-06-12 2021-03-17 Vaxart, Inc. Formulierungen zur freisetzung von rsv- und norovirus-antigenen im dünndarm
EP3785716A4 (de) * 2018-04-24 2022-03-02 Shionogi & Co., Ltd Feste formulierung mit ausgezeichneter stabilität
WO2019208540A1 (ja) * 2018-04-24 2019-10-31 塩野義製薬株式会社 安定性に優れた固形製剤

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3172570D1 (en) * 1981-03-11 1985-11-14 Mirko Beljanski Serpentine, alstonine and sempervirine drugs for the specific inhibition of tumurous and cancerous cells
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
DE3523454A1 (de) * 1985-07-01 1987-01-08 Eberhard Prof Dr Nuernberg Formkoerper
US4925674A (en) * 1988-08-25 1990-05-15 Himedics, Inc. Amoxicillin microencapsulated granules
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
JPH05294839A (ja) * 1992-04-20 1993-11-09 Biomaterial Universe Kk シスプラチン含有生体内分解吸収性高分子の微小球お よびその製造法
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
JPH07112932A (ja) * 1993-08-27 1995-05-02 Mitsui Toatsu Chem Inc 徐放性医薬製剤
JPH0789849A (ja) * 1993-09-20 1995-04-04 Fujisawa Pharmaceut Co Ltd 徐放性製剤
JPH0859460A (ja) * 1994-08-22 1996-03-05 Tanaka Kikinzoku Kogyo Kk 抗ガン剤内包キトサンミクロスフェア及びその製造法
US5637319A (en) * 1995-03-01 1997-06-10 Takada; Kanji Controlled-release preparations
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
DK0929293T3 (da) * 1996-08-23 2004-02-02 Sequus Pharm Inc Liposomer indeholdende en cisplatinforbindelse

Also Published As

Publication number Publication date
PL191631B1 (pl) 2006-06-30
HUP0001719A3 (en) 2005-11-28
PL335107A1 (en) 2000-04-10
HUP0001719A2 (hu) 2000-11-28
AU6626798A (en) 1998-08-26
IN187998B (de) 2002-08-03
CA2282082C (fr) 2005-10-18
BG103647A (en) 2000-03-31
NZ337216A (en) 2000-09-29
US6458389B1 (en) 2002-10-01
ES2210726T3 (es) 2004-07-01
AR011133A1 (es) 2000-08-02
ZA981123B (en) 1998-08-20
DK0971702T3 (da) 2004-04-13
FR2759293B1 (fr) 1999-04-30
HU225425B1 (en) 2006-11-28
JP2001512433A (ja) 2001-08-21
PT971702E (pt) 2004-04-30
JP4549445B2 (ja) 2010-09-22
BR9807319A (pt) 2000-04-18
NO323230B1 (no) 2007-02-05
EA001760B1 (ru) 2001-08-27
EP0971702A1 (de) 2000-01-19
NO993881D0 (no) 1999-08-11
NO993881L (no) 1999-09-29
KR100471672B1 (ko) 2005-03-07
FR2759293A1 (fr) 1998-08-14
TW561055B (en) 2003-11-11
KR20000070997A (ko) 2000-11-25
EA199900734A1 (ru) 2000-04-24
CA2282082A1 (fr) 1998-08-13
BG64247B1 (bg) 2004-07-30
WO1998034599A1 (fr) 1998-08-13
EP0971702B1 (de) 2003-12-03
AU744001B2 (en) 2002-02-14
US20030017210A1 (en) 2003-01-23
IL131326A (en) 2005-03-20
DE69820239D1 (de) 2004-01-15
IL131326A0 (en) 2001-01-28
DE69820239T2 (de) 2004-10-07

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