AR011133A1 - MICROGRÁNULOS DE LIBERACIoN CONTROLADA QUE CONTIENEN CISPLATINO , PROCEDIMIENTO DE SU PREPARACIoN, COMPOSICIoN FARMACÉUTICA Y UTILIZACIoN EN LA FABRICACIoN DE UN MEDICAMENTO POLIQUIMIOTERAPIA O EN ASOCIACIoN CON UNA RADIOTERAPIA. - Google Patents
MICROGRÁNULOS DE LIBERACIoN CONTROLADA QUE CONTIENEN CISPLATINO , PROCEDIMIENTO DE SU PREPARACIoN, COMPOSICIoN FARMACÉUTICA Y UTILIZACIoN EN LA FABRICACIoN DE UN MEDICAMENTO POLIQUIMIOTERAPIA O EN ASOCIACIoN CON UNA RADIOTERAPIA.Info
- Publication number
- AR011133A1 AR011133A1 ARP980100613A ARP980100613A AR011133A1 AR 011133 A1 AR011133 A1 AR 011133A1 AR P980100613 A ARP980100613 A AR P980100613A AR P980100613 A ARP980100613 A AR P980100613A AR 011133 A1 AR011133 A1 AR 011133A1
- Authority
- AR
- Argentina
- Prior art keywords
- association
- manufacture
- controlled release
- procedure
- polychimotherapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se refiere a una nueva formulacion de cisplatina, para administracion oral, en forma de microgránulos de liberacion controlada, así como su procedimientode preparacion por montaje en medio acuoso. La misma se refiere también a una preparacionfarma céutica que contiene los microgránulos de cisplatina deliberacion controlada y un agente anticanceroso como producto de combinacion para una utilizacion simultánea, separada o extendida en el tiempo en terapiaanticancerosa, así como lautilizacion de dichos microgránulos para fabricar un medicamento para administrar por vía oral destinado a ser utilizado enpoliquimioterapia o en asociacion con una radioterapia.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9701545A FR2759293B1 (fr) | 1997-02-11 | 1997-02-11 | Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie |
Publications (1)
Publication Number | Publication Date |
---|---|
AR011133A1 true AR011133A1 (es) | 2000-08-02 |
Family
ID=9503556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980100613A AR011133A1 (es) | 1997-02-11 | 1998-02-11 | MICROGRÁNULOS DE LIBERACIoN CONTROLADA QUE CONTIENEN CISPLATINO , PROCEDIMIENTO DE SU PREPARACIoN, COMPOSICIoN FARMACÉUTICA Y UTILIZACIoN EN LA FABRICACIoN DE UN MEDICAMENTO POLIQUIMIOTERAPIA O EN ASOCIACIoN CON UNA RADIOTERAPIA. |
Country Status (24)
Country | Link |
---|---|
US (2) | US6458389B1 (es) |
EP (1) | EP0971702B1 (es) |
JP (1) | JP4549445B2 (es) |
KR (1) | KR100471672B1 (es) |
AR (1) | AR011133A1 (es) |
AT (1) | ATE255409T1 (es) |
BG (1) | BG64247B1 (es) |
BR (1) | BR9807319A (es) |
CA (1) | CA2282082C (es) |
DE (1) | DE69820239T2 (es) |
DK (1) | DK0971702T3 (es) |
EA (1) | EA001760B1 (es) |
ES (1) | ES2210726T3 (es) |
FR (1) | FR2759293B1 (es) |
HU (1) | HU225425B1 (es) |
IL (1) | IL131326A (es) |
IN (1) | IN187998B (es) |
NO (1) | NO323230B1 (es) |
NZ (1) | NZ337216A (es) |
PL (1) | PL191631B1 (es) |
PT (1) | PT971702E (es) |
TW (1) | TW561055B (es) |
WO (1) | WO1998034599A1 (es) |
ZA (1) | ZA981123B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050096304A1 (en) * | 1998-09-08 | 2005-05-05 | David White | Method of treating cancer using dithiocarbamate derivatives |
FR2790668B1 (fr) * | 1999-03-12 | 2002-07-26 | D B F | Granules contenant une substance vegetale et leur procede de preparation |
BR0010649A (pt) * | 1999-05-17 | 2002-02-19 | D B F | Grãnulos que contêm pelo menos uma substância vegetal e processo de preparação dos mesmos |
JP5171038B2 (ja) * | 2003-10-10 | 2013-03-27 | エティファルム | イチョウ・エキスを含む放出持続性の微小顆粒およびそのような顆粒の製造方法 |
FR2861990B1 (fr) | 2003-11-10 | 2006-02-10 | Nouveaux Produits Pharma | Comprimes faiblement doses a reseau de polymeres |
AR052142A1 (es) * | 2004-11-18 | 2007-03-07 | Bristol Myers Squibb Co | Perla recubierta enterica que comprende ixabepilona, y preparacion y administracion de la misma |
JPWO2006062072A1 (ja) * | 2004-12-10 | 2008-08-07 | テムリック株式会社 | 転移癌治療剤および癌転移抑制剤 |
US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
FR2918566B1 (fr) | 2007-07-11 | 2009-10-09 | Pierre Fabre Medicament Sa | Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine. |
FR2918567B1 (fr) * | 2007-07-11 | 2012-08-03 | Pf Medicament | Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine. |
JP5204846B2 (ja) * | 2007-09-21 | 2013-06-05 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | エタノールの影響に対して耐性を有する非オピオイド薬のpH依存性制御放出医薬組成物 |
CN101801357B (zh) * | 2007-09-21 | 2013-08-07 | 赢创罗姆有限公司 | 耐受乙醇的影响的pH依赖性受控释放的药物组合物 |
MX2010007577A (es) * | 2008-01-10 | 2010-08-04 | Evonik Roehm Gmbh | Preparacion nutriceutica o farmaceutica revestida con una sustancia activa mejorada liberada en el colon. |
BRPI0821985A2 (pt) * | 2008-01-10 | 2015-06-23 | Evonik Roehm Gmbh | Preparacao farmacêutica ou nutracêutica revestida tendo liberação de substância ativa controlada |
DK177529B1 (en) * | 2009-10-23 | 2013-09-08 | Bio Bedst Aps | Liposomes with improved storage stability |
CA2688202C (en) * | 2009-12-11 | 2012-11-13 | Bj Services Company | Viscoelastic fluids containing hydroxyethyl cellulose |
EP2371356B1 (en) * | 2010-03-12 | 2012-12-19 | Phoeme GmbH | Multi-particle pharmaceutical formulation for colon absorption |
US8070047B1 (en) * | 2010-12-02 | 2011-12-06 | Rohm And Haas Electronic Materials Llc | Flux composition and method of soldering |
JP2015530387A (ja) | 2012-09-04 | 2015-10-15 | エライゾン ファーマシューティカルズ, エルエルシー | 脂質複合体化シスプラチンによる肺癌の再発防止 |
CA2959414C (en) | 2014-09-05 | 2023-03-14 | Symbiomix Therapeutics, Llc | Secnidazole for use in the treatment of bacterial vaginosis |
US10238688B2 (en) * | 2015-04-24 | 2019-03-26 | Genedia Biotech Co., Ltd. | Combination therapies for bladder cancer |
WO2016196653A1 (en) * | 2015-06-01 | 2016-12-08 | Symbiomix Therapeutics, Llc | Novel nitroimidazole formulations and uses thereof |
US11433146B2 (en) | 2015-06-12 | 2022-09-06 | Vaxart, Inc. | Formulations for small intestinal delivery of RSV and norovirus antigens |
CN112236146A (zh) * | 2018-04-24 | 2021-01-15 | 盐野义制药株式会社 | 稳定性优良的固体制剂 |
MX2020011130A (es) * | 2018-04-24 | 2022-09-09 | Shionogi & Co | Forma de dosificacion solida que tiene excelente estabilidad. |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0059817B1 (fr) * | 1981-03-11 | 1985-10-09 | Mirko Beljanski | Serpentine; alstonine et sempervirine, médicaments inhibant spécifiquement les cellules cancéreuses et tumorales |
IT1153974B (it) * | 1982-09-23 | 1987-01-21 | Erba Farmitalia | Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento |
DE3421468A1 (de) * | 1984-06-08 | 1985-12-19 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung |
DE3523454A1 (de) * | 1985-07-01 | 1987-01-08 | Eberhard Prof Dr Nuernberg | Formkoerper |
US4925674A (en) * | 1988-08-25 | 1990-05-15 | Himedics, Inc. | Amoxicillin microencapsulated granules |
US5399363A (en) * | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
JPH05294839A (ja) * | 1992-04-20 | 1993-11-09 | Biomaterial Universe Kk | シスプラチン含有生体内分解吸収性高分子の微小球お よびその製造法 |
US5795882A (en) * | 1992-06-22 | 1998-08-18 | Bone Care International, Inc. | Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations |
JPH07112932A (ja) * | 1993-08-27 | 1995-05-02 | Mitsui Toatsu Chem Inc | 徐放性医薬製剤 |
JPH0789849A (ja) * | 1993-09-20 | 1995-04-04 | Fujisawa Pharmaceut Co Ltd | 徐放性製剤 |
JPH0859460A (ja) * | 1994-08-22 | 1996-03-05 | Tanaka Kikinzoku Kogyo Kk | 抗ガン剤内包キトサンミクロスフェア及びその製造法 |
US5637319A (en) * | 1995-03-01 | 1997-06-10 | Takada; Kanji | Controlled-release preparations |
US5614206A (en) * | 1995-03-07 | 1997-03-25 | Wright Medical Technology, Inc. | Controlled dissolution pellet containing calcium sulfate |
DK0929293T3 (da) * | 1996-08-23 | 2004-02-02 | Sequus Pharm Inc | Liposomer indeholdende en cisplatinforbindelse |
-
1997
- 1997-02-11 FR FR9701545A patent/FR2759293B1/fr not_active Expired - Lifetime
-
1998
- 1998-02-10 EP EP98908157A patent/EP0971702B1/fr not_active Expired - Lifetime
- 1998-02-10 JP JP53389798A patent/JP4549445B2/ja not_active Expired - Lifetime
- 1998-02-10 ES ES98908157T patent/ES2210726T3/es not_active Expired - Lifetime
- 1998-02-10 DE DE69820239T patent/DE69820239T2/de not_active Expired - Lifetime
- 1998-02-10 HU HU0001719A patent/HU225425B1/hu not_active IP Right Cessation
- 1998-02-10 PL PL335107A patent/PL191631B1/pl not_active IP Right Cessation
- 1998-02-10 IN IN337DE1998 patent/IN187998B/en unknown
- 1998-02-10 BR BR9807319-2A patent/BR9807319A/pt not_active Application Discontinuation
- 1998-02-10 IL IL13132698A patent/IL131326A/xx not_active IP Right Cessation
- 1998-02-10 CA CA002282082A patent/CA2282082C/fr not_active Expired - Lifetime
- 1998-02-10 US US09/367,270 patent/US6458389B1/en not_active Expired - Lifetime
- 1998-02-10 AT AT98908157T patent/ATE255409T1/de active
- 1998-02-10 EA EA199900734A patent/EA001760B1/ru not_active IP Right Cessation
- 1998-02-10 PT PT98908157T patent/PT971702E/pt unknown
- 1998-02-10 DK DK98908157T patent/DK0971702T3/da active
- 1998-02-10 TW TW087101722A patent/TW561055B/zh not_active IP Right Cessation
- 1998-02-10 WO PCT/FR1998/000251 patent/WO1998034599A1/fr active IP Right Grant
- 1998-02-10 KR KR10-1999-7007263A patent/KR100471672B1/ko not_active IP Right Cessation
- 1998-02-10 NZ NZ337216A patent/NZ337216A/xx not_active IP Right Cessation
- 1998-02-11 AR ARP980100613A patent/AR011133A1/es active IP Right Grant
- 1998-02-11 ZA ZA981123A patent/ZA981123B/xx unknown
-
1999
- 1999-08-10 BG BG103647A patent/BG64247B1/bg unknown
- 1999-08-11 NO NO19993881A patent/NO323230B1/no not_active IP Right Cessation
-
2002
- 2002-07-25 US US10/200,998 patent/US20030017210A1/en not_active Abandoned
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